LOCUS       NP_001178742             672 aa            linear   ROD 28-JUL-2024
DEFINITION  Holliday junction recognition protein [Rattus norvegicus].
ACCESSION   NP_001178742 XP_237403
VERSION     NP_001178742.1
DBSOURCE    REFSEQ: accession NM_001191813.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (residues 1 to 672)
  AUTHORS   Zasadzinska,E., Barnhart-Dailey,M.C., Kuich,P.H. and Foltz,D.R.
  TITLE     Dimerization of the CENP-A assembly factor HJURP is required for
            centromeric nucleosome deposition
  JOURNAL   EMBO J 32 (15), 2113-2124 (2013)
   PUBMED   23771058
REFERENCE   2  (residues 1 to 672)
  AUTHORS   Burgess,R.J. and Zhang,Z.
  TITLE     Histone chaperones in nucleosome assembly and human disease
  JOURNAL   Nat Struct Mol Biol 20 (1), 14-22 (2013)
   PUBMED   23288364
  REMARK    Review article
REFERENCE   3  (residues 1 to 672)
  AUTHORS   Kim,I.S., Lee,M., Park,K.C., Jeon,Y., Park,J.H., Hwang,E.J.,
            Jeon,T.I., Ko,S., Lee,H., Baek,S.H. and Kim,K.I.
  TITLE     Roles of Mis18alpha in epigenetic regulation of centromeric
            chromatin and CENP-A loading
  JOURNAL   Mol Cell 46 (3), 260-273 (2012)
   PUBMED   22516971
REFERENCE   4  (residues 1 to 672)
  AUTHORS   Hu,H., Liu,Y., Wang,M., Fang,J., Huang,H., Yang,N., Li,Y., Wang,J.,
            Yao,X., Shi,Y., Li,G. and Xu,R.M.
  TITLE     Structure of a CENP-A-histone H4 heterodimer in complex with
            chaperone HJURP
  JOURNAL   Genes Dev 25 (9), 901-906 (2011)
   PUBMED   21478274
REFERENCE   5  (residues 1 to 672)
  AUTHORS   Dunleavy,E.M., Roche,D., Tagami,H., Lacoste,N., Ray-Gallet,D.,
            Nakamura,Y., Daigo,Y., Nakatani,Y. and Almouzni-Pettinotti,G.
  TITLE     HJURP is a cell-cycle-dependent maintenance and deposition factor
            of CENP-A at centromeres
  JOURNAL   Cell 137 (3), 485-497 (2009)
   PUBMED   19410545
REFERENCE   6  (residues 1 to 672)
  AUTHORS   Foltz,D.R., Jansen,L.E., Bailey,A.O., Yates,J.R. 3rd, Bassett,E.A.,
            Wood,S., Black,B.E. and Cleveland,D.W.
  TITLE     Centromere-specific assembly of CENP-a nucleosomes is mediated by
            HJURP
  JOURNAL   Cell 137 (3), 472-484 (2009)
   PUBMED   19410544
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000009.1.
            
            On Jul 17, 2010 this sequence version replaced XP_237403.4.
            
            Sequence Note:.
            
            ##Evidence-Data-START##
            RNAseq introns :: partial sample support SAMN12840107 [ECO:0000350]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..672
                     /organism="Rattus norvegicus"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="9"
                     /map="9q35"
     Protein         1..672
                     /product="Holliday junction recognition protein"
                     /calculated_mol_wt=74703
     Region          254..373
                     /region_name="HJURP_mid"
                     /note="Holliday junction recognition protein-associated
                     repeat; pfam12346"
                     /db_xref="CDD:463542"
     Region          392..453
                     /region_name="HJURP_C"
                     /note="Holliday junction regulator protein family
                     C-terminal repeat; pfam12347"
                     /db_xref="CDD:463543"
     Region          533..589
                     /region_name="HJURP_C"
                     /note="Holliday junction regulator protein family
                     C-terminal repeat; pfam12347"
                     /db_xref="CDD:463543"
     CDS             1..672
                     /gene="Hjurp"
                     /gene_synonym="RGD1305846"
                     /coded_by="NM_001191813.2:96..2114"
                     /db_xref="GeneID:316602"
                     /db_xref="RGD:1305846"
ORIGIN      
        1 mesmnlrdrp ldqrlkessr rfqtymqrli akynqpfedd plvqmatlty etpqglrvwg
       61 gklikeedee htqvigglse qapggdsdss gadtsleeae wpscnltrea sgdtgkhqlt
      121 vpgntlktdl rrkyltqvdi llqdaeyfkn tqkgdgkdtv ttcfpswtsp vtpapgcqdg
      181 ipaksfggpe gsasscgdqa ssypcpadmt ivtrndsfsl lgassnsvsn qcpevddisn
      241 vtisdlyegm mhsmsrllrs kpsciistkt sinrnwklkr rlsrkhgvhk nttychrskp
      301 fqrssrkgpl hcseprkear vlrdsknlph vdphktdktg lelesvpleg sklqvhklsp
      361 awkelqglpq kylglstvnh lgredrvkal qwlispvkma prlrvppgqv enwyrevkik
      421 feklhqeccp spekrlrltg ptqswaadmy rggskspgsr qsvethklss plsrekterp
      481 geafedlrgr svktnscllr rgpspedsps qspghsqqrs ghlqehnsep irkaawpsta
      541 isapdfpdcg ghydelkkef nrlyqkyclv sprhakvtlc grlspvkaaa avpgqtehlk
      601 rlnpdsplqs sqkwspspdw riripqdsta veghrsaqta savvrgpwls tkrrklsypa
      661 kspdssgaag rl
//
