LOCUS       NP_077051               2437 aa            linear   ROD 30-JUL-2024
DEFINITION  human immunodeficiency virus type I enhancer-binding protein 2
            homolog [Rattus norvegicus].
ACCESSION   NP_077051 XP_346527
VERSION     NP_077051.1
DBSOURCE    REFSEQ: accession NM_024137.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (residues 1 to 2437)
  AUTHORS   Dorflinger,U., Pscherer,A., Moser,M., Rummele,P., Schule,R. and
            Buettner,R.
  TITLE     Activation of somatostatin receptor II expression by transcription
            factors MIBP1 and SEF-2 in the murine brain
  JOURNAL   Mol Cell Biol 19 (5), 3736-3747 (1999)
   PUBMED   10207097
REFERENCE   2  (residues 1 to 2437)
  AUTHORS   Makino,R., Akiyama,K., Yasuda,J., Mashiyama,S., Honda,S., Sekiya,T.
            and Hayashi,K.
  TITLE     Cloning and characterization of a c-myc intron binding protein
            (MIBP1)
  JOURNAL   Nucleic Acids Res 22 (25), 5679-5685 (1994)
   PUBMED   7838722
REFERENCE   3  (residues 1 to 2437)
  AUTHORS   Ron,D., Brasier,A.R. and Habener,J.F.
  TITLE     Angiotensinogen gene-inducible enhancer-binding protein 1, a member
            of a new family of large nuclear proteins that recognize nuclear
            factor kappa B-binding sites through a zinc finger motif
  JOURNAL   Mol Cell Biol 11 (5), 2887-2895 (1991)
   PUBMED   2017183
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from D37951.1.
            
            On Jan 12, 2005 this sequence version replaced XP_346527.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: D37951.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132266, SAMD00132281
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..2437
                     /organism="Rattus norvegicus"
                     /strain="Sprague-Dawley"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1p13"
     Protein         1..2437
                     /product="human immunodeficiency virus type I
                     enhancer-binding protein 2 homolog"
                     /note="MIBP-1; DNA-binding protein AGIE-BP1; myc
                     intron-binding protein 1; angiotensinogen gene-inducible
                     enhancer-binding protein 1; human immunodeficiency virus
                     type 1 enhancer-binding protein 2; c-myc intron binding
                     protein 1; human immunodeficiency virus type I enhancer
                     binding protein 2"
                     /calculated_mol_wt=267296
     Region          1..121
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (Q00900.2)"
     Region          189..211
                     /region_name="zf-C2H2"
                     /note="Zinc finger, C2H2 type; pfam00096"
                     /db_xref="CDD:395048"
     Region          191..211
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          204..228
                     /region_name="zf-H2C2_2"
                     /note="Zinc-finger double domain; pfam13465"
                     /db_xref="CDD:463886"
     Region          219..239
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          271..304
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (Q00900.2)"
     Region          340..416
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (Q00900.2)"
     Region          717..1002
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (Q00900.2)"
     Site            816
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0007744|PubMed:22673903; propagated from
                     UniProtKB/Swiss-Prot (Q00900.2)"
     Region          <824..>935
                     /region_name="PTZ00441"
                     /note="sporozoite surface protein 2 (SSP2); Provisional"
                     /db_xref="CDD:240420"
     Region          934..940
                     /region_name="Nuclear localization signal.
                     /evidence=ECO:0000255"
                     /note="propagated from UniProtKB/Swiss-Prot (Q00900.2)"
     Site            947
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0000250|UniProtKB:Q3UHF7; propagated from
                     UniProtKB/Swiss-Prot (Q00900.2)"
     Site            952
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0000250|UniProtKB:Q3UHF7; propagated from
                     UniProtKB/Swiss-Prot (Q00900.2)"
     Site            1045
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0000250|UniProtKB:Q3UHF7; propagated from
                     UniProtKB/Swiss-Prot (Q00900.2)"
     Region          1284..1305
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (Q00900.2)"
     Site            1438
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0007744|PubMed:22673903; propagated from
                     UniProtKB/Swiss-Prot (Q00900.2)"
     Site            1442
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0000250|UniProtKB:Q3UHF7; propagated from
                     UniProtKB/Swiss-Prot (Q00900.2)"
     Region          1480..1591
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (Q00900.2)"
     Region          1790..1812
                     /region_name="zf-C2H2"
                     /note="Zinc finger, C2H2 type; pfam00096"
                     /db_xref="CDD:395048"
     Region          1792..1812
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275370"
     Site            order(1797,1799,1801,1803..1804,1807..1808,1811,1825,
                     1827..1829,1831..1832,1836)
                     /site_type="other"
                     /note="putative nucleic acid binding site [nucleotide
                     binding]"
                     /db_xref="CDD:275370"
     Region          1804..1829
                     /region_name="zf-H2C2_2"
                     /note="Zinc-finger double domain; pfam13465"
                     /db_xref="CDD:463886"
     Region          1820..1838
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275370"
     Region          1843..1877
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275371"
     Region          1855..1938
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (Q00900.2)"
     Region          1993..2125
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (Q00900.2)"
     Region          <2024..>2167
                     /region_name="PTZ00449"
                     /note="104 kDa microneme/rhoptry antigen; Provisional"
                     /db_xref="CDD:185628"
     Region          2044..2139
                     /region_name="10 X 4 AA tandem repeats of
                     S-P-[RGMKC]-[RK]"
                     /note="propagated from UniProtKB/Swiss-Prot (Q00900.2)"
     Site            2109
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0000250|UniProtKB:P31629; propagated from
                     UniProtKB/Swiss-Prot (Q00900.2)"
     Region          2233..2316
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (Q00900.2)"
     Site            2288
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0000250|UniProtKB:P31629; propagated from
                     UniProtKB/Swiss-Prot (Q00900.2)"
     Site            2292
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0000250|UniProtKB:P31629; propagated from
                     UniProtKB/Swiss-Prot (Q00900.2)"
     Region          2364..2437
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (Q00900.2)"
     Site            2420
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0000250|UniProtKB:Q3UHF7; propagated from
                     UniProtKB/Swiss-Prot (Q00900.2)"
     Site            2422
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0000250|UniProtKB:Q3UHF7; propagated from
                     UniProtKB/Swiss-Prot (Q00900.2)"
     CDS             1..2437
                     /gene="Hivep2"
                     /gene_synonym="MIBP1"
                     /coded_by="NM_024137.1:767..8080"
                     /db_xref="GeneID:29721"
                     /db_xref="RGD:61988"
ORIGIN      
        1 mdtgdtalgq katsrsgetd svsgrwrqeq saglkmstfs sqegqrqpqi dpdqignvas
       61 aqlfgsgkla spgegvhqvt ekqypphrps pypcqhslsf pqhslpqgmm hsnkphqsle
      121 gppwlfsgpl psvasedlfp fpmhghssgy prkkisslnp aysqysqksi eqaedahkke
      181 hkpkkpgkyi cpycsracak psvlkkhirs htgerpypci pcgfsfktks nlykhrksha
      241 haikaglvpf tessvskldl eagfidveae ihsdgeqstd tdeesslfae asdkvspgpp
      301 ipldiasrgg ypgsleeslg gpmkvpilii pksgiplpne gsqylgpdml pnpslnakad
      361 dshtvkqkla lrlsekkgqd sepslnllsp hskgstdsgy fsrsesaeqq isppntnaks
      421 yeeiifgkyc rlsprntlsv tptgqertam grrglveplp hvntrlevkm fedpitqlip
      481 skgemdpsqv nmlkttkfns ecrqpqamaa svrnegkpyp gsfpgsnpil leapvdsspl
      541 irsnsmptss atnlsippsl rgshsfderm tgsddvfypg tvgippqrml rrqaafelps
      601 vqeghmefeh parvpkilag sslkekklvp gdrsgydyda crkpykkwed petpkqsyrd
      661 isclstfkhg geyfmdpsvp lpgvptmfgt tcenrkrrke ksvgdeedtp micggmgsap
      721 gsmmsseyds klqdggrsgf tmtgheslph gysdrldlar pqlpsrspsl gsedlpsagd
      781 pdkmtdlgkk ppgnvisviq htnslsrpns fersestema vstqdktpsp semgdsevle
      841 gpvspewapp gdgaesgsrp tpsqqvpqhs yhgqprlvrq hniqvpeirv teepdkpeke
      901 keaptkepek pveefqwpqr setlsqlpae klppkkkrlr ladmehssge ssfestgtgl
      961 srspsqesnl shsssfsmsf drdetvklta ppkqdesgkh sefltvpags yslsvpghhh
     1021 qkemrrcsse qmpcphptev peirsksfdy gnlshapvag aspstlspsr erkkcflvrq
     1081 asfsgspeia qgeagmdpsv kqeqleqlha glraawttvl pplpgddpgk qvvgpcgqls
     1141 sgpplhlaqq qimhmdsqes lrnpliqpts ymtgkhlpeq phlfphqdav pfspiqnalf
     1201 qfqyptvcmv hlpaqqppww qahfphpftp hpqnsyskpp fqadihssys lehvaehtgk
     1261 ksadyphake qtypcysgas glhsknlppk fpsdpgskst eappteqllr edfasenagp
     1321 lqslpgtvvp vriqthvpsy gsvmytsisq ilgqnspaiv ickvdenmtq rtlvtnaamq
     1381 gigfniaqvl gqrtglekyp lwkvpqtlpl glessiplcl pstsdsaasl ggskrmlspa
     1441 sslelfmetk qqkrvkeekm ygqiveelsa veltnsdikk glsrpqkpql vrqgcasepk
     1501 dgssqsrsss fsslspsssq dhpaasgpfp pnreilsgsr apprrkfsgp sesressdel
     1561 didetssdms mspqssslpt ggsqqedegk arklpvsmlv hmasgpggnv anstllftdv
     1621 adfqqilqfp slrttttvsw cflnytkpnf vqqatfkssv yaswcisscn pnpsglntkt
     1681 tlallrskqk itaeiytlaa mhrpgtgklt sssawkqfaq mkpdapflfg nklerklggn
     1741 vlkergkgei hgdkdlgskq tepirikife ggyksnedyv yvrgrgrgky iceecgirck
     1801 kpsmlkkhir thtdvrpyvc klcnfafktk gnltkhmksk ahmkkclelg vsmtsvdete
     1861 teeaenmedl hktsekhsms gistdhqfsd aeesdgedgd dndeddeddd dfddqgdltp
     1921 ktrsrstspq pprfsslpvn vgavahgvps dsslghssli sylvtlpsiq vtqlmtpsds
     1981 cedtqmteyq rlfqskstds epdkdrldip ssmdeeamls sepsssprdf spssyrsspg
     2041 ydsspcrdns pkrylipkgd lsprrhlspr rdlspmrhls prkeaalrre msqgdasprr
     2101 hlsprrplsp gkdittrrdl sprrerrymt tirapsprra lyhnpplpmg qylqtepivl
     2161 gppnlrrglp qvpyfslygd qegayehhgs slfpegptdy vfshlplhsq qqvrapipmv
     2221 pvggiqmvhs lppaisglhp pptlplpteg seekkgapge altqdpytls rrhekqaphv
     2281 lqssglpssp ssprllmkqs tsedslnste reqeeniqtc tkaiaslria teeaallgad
     2341 qptwvqespq kplesahisi rhfsgpepgq lctsaahpdl hdgekdtfgt sqtavahptf
     2401 yskgsvdekq vdfqsskels lsteegneps seknrlh
//
