LOCUS       NM_001100825             960 bp    mRNA    linear   ROD 20-SEP-2024
DEFINITION  Rattus norvegicus histidine triad nucleotide binding protein 3
            (Hint3), transcript variant 1, mRNA.
ACCESSION   NM_001100825 XM_001055373 XM_341742
VERSION     NM_001100825.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 960)
  AUTHORS   Morgenstern,M., Peikert,C.D., Lubbert,P., Suppanz,I., Klemm,C.,
            Alka,O., Steiert,C., Naumenko,N., Schendzielorz,A., Melchionda,L.,
            Muhlhauser,W.W.D., Knapp,B., Busch,J.D., Stiller,S.B.,
            Dannenmaier,S., Lindau,C., Licheva,M., Eickhorst,C., Galbusera,R.,
            Zerbes,R.M., Ryan,M.T., Kraft,C., Kozjak-Pavlovic,V., Drepper,F.,
            Dennerlein,S., Oeljeklaus,S., Pfanner,N., Wiedemann,N. and
            Warscheid,B.
  TITLE     Quantitative high-confidence human mitochondrial proteome and its
            dynamics in cellular context
  JOURNAL   Cell Metab 33 (12), 2464-2483 (2021)
   PUBMED   34800366
REFERENCE   2  (bases 1 to 960)
  AUTHORS   Chou,T.F., Cheng,J., Tikh,I.B. and Wagner,C.R.
  TITLE     Evidence that human histidine triad nucleotide binding protein 3
            (Hint3) is a distinct branch of the histidine triad (HIT)
            superfamily
  JOURNAL   J Mol Biol 373 (4), 978-989 (2007)
   PUBMED   17870088
REFERENCE   3  (bases 1 to 960)
  AUTHORS   Brenner,C.
  TITLE     Hint, Fhit, and GalT: function, structure, evolution, and mechanism
            of three branches of the histidine triad superfamily of nucleotide
            hydrolases and transferases
  JOURNAL   Biochemistry 41 (29), 9003-9014 (2002)
   PUBMED   12119013
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000001.1 and CB741212.1.
            
            On or before Feb 16, 2013 this sequence version replaced
            XM_341742.3, XM_001055373.3.
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes the longer isoform (1).
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: FQ215151.1, AY040767.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-143               JAXUCZ010000001.1  28854860-28855002
            144-598             CB741212.1         1-455
            599-960             JAXUCZ010000001.1  28864362-28864723
FEATURES             Location/Qualifiers
     source          1..960
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1p11"
     gene            1..960
                     /gene="Hint3"
                     /gene_synonym="HINT-3; HINT-4; Hint4"
                     /note="histidine triad nucleotide binding protein 3"
                     /db_xref="GeneID:246769"
                     /db_xref="RGD:621603"
     exon            1..210
                     /gene="Hint3"
                     /gene_synonym="HINT-3; HINT-4; Hint4"
                     /inference="alignment:Splign:2.1.0"
     CDS             31..558
                     /gene="Hint3"
                     /gene_synonym="HINT-3; HINT-4; Hint4"
                     /EC_number="3.-.-.-"
                     /note="isoform 1 is encoded by transcript variant 1;
                     histidine triad nucleotide binding protein 4; adenosine
                     5'-monophosphoramidase HINT3"
                     /codon_start=1
                     /product="adenosine 5'-monophosphoramidase HINT3 isoform
                     1"
                     /protein_id="NP_001094295.1"
                     /db_xref="GeneID:246769"
                     /db_xref="RGD:621603"
                     /translation="MAEKQAGLAGEPNPDCTVTAKAGPEVSSPGTSESRDYDSNCVFC
                     RVAAGQEPETELLYCENKDLVCFKDIKPAALHHYLVVPKKHIGSCKDLNKDHIEMVES
                     MVTVGKTILERNNFTDFTDVRMGFHVPPFCSVSHLHLHVIAPAKEFGFLSRVVYRRDS
                     YWFITVDYLLEKLRK"
     exon            211..328
                     /gene="Hint3"
                     /gene_synonym="HINT-3; HINT-4; Hint4"
                     /inference="alignment:Splign:2.1.0"
     exon            329..398
                     /gene="Hint3"
                     /gene_synonym="HINT-3; HINT-4; Hint4"
                     /inference="alignment:Splign:2.1.0"
     exon            399..525
                     /gene="Hint3"
                     /gene_synonym="HINT-3; HINT-4; Hint4"
                     /inference="alignment:Splign:2.1.0"
     exon            526..960
                     /gene="Hint3"
                     /gene_synonym="HINT-3; HINT-4; Hint4"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agctgatcct caggtcgcct ctcggccgcc atggctgaaa agcaagcggg cttagctgga
       61 gagccgaatc ccgactgtac ggtcactgcc aaagcaggac ctgaggtgtc ctcgcctggg
      121 acctcggagt ccagggacta tgacagtaac tgcgtgttct gccgcgtcgc ggcgggtcag
      181 gaacccgaaa ctgaactctt atactgtgag aacaaagacc tggtttgttt caaagatatc
      241 aaaccagcag cacttcacca ttacctcgtg gtgccaaaaa agcatattgg aagttgcaag
      301 gatctaaaca aagatcacat agaaatggtt gagagcatgg tcactgttgg aaaaaccatt
      361 cttgagagga ataatttcac agacttcaca gatgtgagaa tgggcttcca tgtgcctccg
      421 ttctgctccg tctctcatct gcaccttcat gtcatagcgc ccgccaaaga gttcggcttc
      481 ctatcgaggg tggtttacag gcgggattcc tactggttta tcacggttga ttatttgctt
      541 gaaaagctaa gaaaataaag atgtgaacca tggacaagtt ctttccctga ctcagagcag
      601 ccgttggttt gctctctgaa ggctaattgc agcctgaagg ttgctggctc acatgtaaca
      661 ctaccactgg ggagccttac atttttttct gaataattat tttctgacat gtcatagtta
      721 tgtgagaatt ttctcactga cttcagtcca tctaatacaa attctgctaa tcaagatgca
      781 tcctgtattt ttttaaagtt caagtttcat ttattaatag tcttaataat aatttgtggt
      841 gaataaattg gcataaaaat tttgaacctt tattatagta aaagagaaaa attagccatt
      901 ttatgacagt tgtatagtct tacacataaa tattcaaaat aaagaatacc atgccactaa
//
