LOCUS       NM_001107955             604 bp    mRNA    linear   ROD 30-MAR-2024
DEFINITION  Rattus norvegicus histidine triad nucleotide binding protein 2
            (Hint2), mRNA.
ACCESSION   NM_001107955 XM_001070128 XM_233377
VERSION     NM_001107955.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 604)
  AUTHORS   Martin,J., Balmer,M.L., Rajendran,S., Maurhofer,O., Dufour,J.F. and
            St-Pierre,M.V.
  TITLE     Nutritional stress exacerbates hepatic steatosis induced by
            deletion of the histidine nucleotide-binding (Hint2) mitochondrial
            protein
  JOURNAL   Am J Physiol Gastrointest Liver Physiol 310 (7), G497-G509 (2016)
   PUBMED   26767982
REFERENCE   2  (bases 1 to 604)
  AUTHORS   Mootha,V.K., Bunkenborg,J., Olsen,J.V., Hjerrild,M.,
            Wisniewski,J.R., Stahl,E., Bolouri,M.S., Ray,H.N., Sihag,S.,
            Kamal,M., Patterson,N., Lander,E.S. and Mann,M.
  TITLE     Integrated analysis of protein composition, tissue diversity, and
            gene regulation in mouse mitochondria
  JOURNAL   Cell 115 (5), 629-640 (2003)
   PUBMED   14651853
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000005.1 and BI282127.1.
            
            On Jan 10, 2008 this sequence version replaced NM_001107955.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BI282127.1, FM049322.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN12840115 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: inferred from homology
            RefSeq Select criteria             :: based on single
                                                  protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..604
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="5"
                     /map="5q22"
     gene            1..604
                     /gene="Hint2"
                     /note="histidine triad nucleotide binding protein 2"
                     /db_xref="GeneID:313491"
                     /db_xref="RGD:1308910"
     CDS             1..492
                     /gene="Hint2"
                     /note="histidine triad nucleotide-binding protein 2,
                     mitochondrial"
                     /codon_start=1
                     /product="adenosine 5'-monophosphoramidase HINT2"
                     /protein_id="NP_001101425.2"
                     /db_xref="GeneID:313491"
                     /db_xref="RGD:1308910"
                     /translation="MAAAVLLAVGMRAAHRTLAAAGSRGAQVRGNAGMSDGSEVAKAQ
                     KAVPGGAAPTIFSRILDRSLPADILYEDQQCLVFRDVAPQAPVHFLVIPRKPIPRISQ
                     AEEDDQQLLGHLLLVAKKIAQAEGLKDGYRLVVNDGKMGAQSVYHLHIHVLGGRQLQW
                     PPG"
     exon            1..81
                     /gene="Hint2"
                     /inference="alignment:Splign:2.1.0"
     exon            82..222
                     /gene="Hint2"
                     /inference="alignment:Splign:2.1.0"
     exon            223..327
                     /gene="Hint2"
                     /inference="alignment:Splign:2.1.0"
     exon            328..400
                     /gene="Hint2"
                     /inference="alignment:Splign:2.1.0"
     exon            401..587
                     /gene="Hint2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atggctgctg ctgtgctgct ggccgtgggt atgcgcgccg cgcacagaac cctagcggcc
       61 gcggggtccc ggggggcgca ggtccgagga aatgcaggta tgtctgacgg gagtgaagtg
      121 gccaaggccc agaaagcagt tcctggagga gcggcgccaa ccatcttctc ccggattttg
      181 gaccggagcc tcccagctga cattctatat gaagatcagc agtgcctagt gttccgagat
      241 gtagcccctc aggctcctgt gcacttcctg gtcattccta gaaagcccat tcctcgaatt
      301 agccaggctg aagaagacga ccaacagctt ctaggacact tactcctcgt ggccaagaag
      361 atagcacagg cggagggtct gaaagatggg tatcgacttg tggttaacga tgggaagatg
      421 ggcgcacaat ctgtgtacca cctgcacatt cacgtactcg gaggccggca actgcagtgg
      481 ccacctggtt aaacctgcca gctgccctgg gaccgcgggc ctggatgctt ggatggagaa
      541 ccggaaaagg gatcctgtga tgttaataaa cgtatttccc cctccgaaaa aaaaaaaaaa
      601 aaaa
//
