LOCUS       NM_001398731            1535 bp    mRNA    linear   ROD 28-MAR-2024
DEFINITION  Rattus norvegicus heat shock protein nuclear import factor hikeshi
            (Hikeshi), transcript variant 1, mRNA.
ACCESSION   NM_001398731 XM_006229662
VERSION     NM_001398731.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1535)
  AUTHORS   Song,J., Kose,S., Watanabe,A., Son,S.Y., Choi,S., Hong,H.,
            Yamashita,E., Park,I.Y., Imamoto,N. and Lee,S.J.
  TITLE     Structural and functional analysis of Hikeshi, a new nuclear
            transport receptor of Hsp70s
  JOURNAL   Acta Crystallogr D Biol Crystallogr 71 (Pt 3), 473-483 (2015)
   PUBMED   25760597
REFERENCE   2  (bases 1 to 1535)
  AUTHORS   Kose,S., Furuta,M. and Imamoto,N.
  TITLE     Hikeshi, a nuclear import carrier for Hsp70s, protects cells from
            heat shock-induced nuclear damage
  JOURNAL   Cell 149 (3), 578-589 (2012)
   PUBMED   22541429
REFERENCE   3  (bases 1 to 1535)
  AUTHORS   Fernandez-Valdivia,R., Zhang,Y., Pai,S., Metzker,M.L. and
            Schumacher,A.
  TITLE     l7Rn6 encodes a novel protein required for clara cell function in
            mouse lung development
  JOURNAL   Genetics 172 (1), 389-399 (2006)
   PUBMED   16157679
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000001.1.
            
            On Dec 22, 2021 this sequence version replaced XM_006229662.4.
            
            ##Evidence-Data-START##
            Transcript exon combination :: FQ216668.1, FQ216759.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760386,
                                           SAMEA5760389 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-183               JAXUCZ010000001.1  153261674-153261856 c
            184-421             JAXUCZ010000001.1  153256764-153257001 c
            422-573             JAXUCZ010000001.1  153243445-153243596 c
            574-692             JAXUCZ010000001.1  153239945-153240063 c
            693-1535            JAXUCZ010000001.1  153237948-153238790 c
FEATURES             Location/Qualifiers
     source          1..1535
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q32"
     gene            1..1535
                     /gene="Hikeshi"
                     /gene_synonym="l7Rn6"
                     /note="heat shock protein nuclear import factor hikeshi"
                     /db_xref="GeneID:293103"
                     /db_xref="RGD:1359455"
     exon            1..183
                     /gene="Hikeshi"
                     /gene_synonym="l7Rn6"
                     /inference="alignment:Splign:2.1.0"
     CDS             154..747
                     /gene="Hikeshi"
                     /gene_synonym="l7Rn6"
                     /note="isoform 1 is encoded by transcript variant 1;
                     protein Hikeshi; Hikeshi, heat shock protein nuclear
                     import factor; lethal, Chr 7, Rinchik 6; uncharacterized
                     protein C11orf73 homolog"
                     /codon_start=1
                     /product="protein Hikeshi isoform 1"
                     /protein_id="NP_001385660.1"
                     /db_xref="GeneID:293103"
                     /db_xref="RGD:1359455"
                     /translation="MFGCLVAGRLVQTAAQQVAEDKFVFDLPDYENINHVVVFMLGTI
                     PFPEGMGGSVYFSYPDSNGVPVWQLLGFVTNGKPSAIFKISGLKSGEGSQHPFGAMNI
                     VRTPSVAQIGISVELLDSLAQQTPVGSAAVSSVDSFTQFTQKMLDNFYNFASSFALSQ
                     AQMTPNPSEMFIPANVVLKWYENFQRRLAQNPLFWKT"
     exon            184..421
                     /gene="Hikeshi"
                     /gene_synonym="l7Rn6"
                     /inference="alignment:Splign:2.1.0"
     exon            422..573
                     /gene="Hikeshi"
                     /gene_synonym="l7Rn6"
                     /inference="alignment:Splign:2.1.0"
     exon            574..692
                     /gene="Hikeshi"
                     /gene_synonym="l7Rn6"
                     /inference="alignment:Splign:2.1.0"
     exon            693..1535
                     /gene="Hikeshi"
                     /gene_synonym="l7Rn6"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agatgcgttc ccgtgttgct atgtagtgga ggggcacgtt ccttcctgca aattctggaa
       61 ggttcttgag ttcaattagg acagtggctg cggaattcct ggtgtccggc ctgaggtgcc
      121 cgctggccga gcagaggcgc cgagggcgct gccatgtttg gctgcctggt ggcggggagg
      181 ctggtgcaaa cagctgcaca gcaagtggca gaggataaat ttgtttttga cttgcctgat
      241 tatgaaaata tcaaccatgt tgtggttttt atgctgggaa caatcccatt tcctgagggg
      301 atgggaggat ctgtctactt ttcctatcct gattcaaatg gggtgccagt atggcagctc
      361 ctaggatttg tcacgaatgg gaagccaagt gccatcttca aaatatcagg tcttaaatct
      421 ggagaaggaa gccagcaccc atttggagcc atgaatattg tgcgaacccc atctgttgcc
      481 cagattggaa tctcggtgga gttgttggac agtttggctc agcagactcc cgtaggcagt
      541 gccgctgtgt cctcggttga ctccttcaca cagttcacac agaagatgtt ggacaacttc
      601 tacaattttg cttcatcatt tgctctctct caggcccaga tgacaccaaa tccatcggaa
      661 atgttcatcc cagcaaatgt ggttctgaaa tggtatgaaa actttcaaag acgactagca
      721 cagaaccctc tcttttggaa aacataattt gaataaaata atttgtcatg tcatgtaaag
      781 gcacgaagtc aaatgggtca tgaagcctac ctttcaaaaa gaacctgctt agtgactatg
      841 agacttataa aacccttata aaaattagaa ccgttgaaca aggaaaatgt tcaatattaa
      901 ttaccttttc ccttgtaagt atgacatact tcttggaggc aaacattttg tatcagctgt
      961 cgttcatttc ttaaaataaa tcctactcac agcagtagca tttgaaatgc catcgcctgt
     1021 gtaacctttc gtttattctc acagtacttt gctggagtag ctaacttgtt tgttgcttgg
     1081 ttttaagggt ctcatgtggc ccagggtggc tagtaactag tgctgtgatc acaggccttc
     1141 tccatcaggc cctgcctaat gtaggtaact ttaaatcaac tctcataatt gggggacttt
     1201 tggaaaacat gtcaaatatg tgttttaaga tagaaaaatt atcttcaggg agtatttctt
     1261 ttctttcttt tttgtgtttt gtttttgaga cagggcctca tgtggcccag gctagactca
     1321 cactccctct gtagctaaga atacgttgtc ctgatgccca gttctggctc ctgagtgctg
     1381 gtattacaga atgcaccacc acattgtttt aggaaatatt ttttaagatt agcaagtttg
     1441 ttgtttttca atcaagaaag gtaggttgtg agtttttatg tctgcagatt gatatgtttt
     1501 tatttaataa attttctatg tttaatacca gtgaa
//
