LOCUS       NM_053320               2067 bp    mRNA    linear   ROD 20-MAR-2023
DEFINITION  Rattus norvegicus HGF activator (Hgfac), mRNA.
ACCESSION   NM_053320 XM_341240
VERSION     NM_053320.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2067)
  AUTHORS   Iida I, Johkura K, Teng R, Kubota S, Cui L, Zhao X, Ogiwara N,
            Okouchi Y, Asanuma K, Nakayama J and Sasaki K.
  TITLE     Immunohistochemical localization of hepatocyte growth factor
            activator (HGFA) in developing mouse liver tissues. Heterogeneous
            distribution of HGFA protein
  JOURNAL   J Histochem Cytochem 51 (9), 1139-1149 (2003)
   PUBMED   12923239
REFERENCE   2  (bases 1 to 2067)
  AUTHORS   Kaibori M, Inoue T, Oda M, Naka D, Kawaguchi T, Kitamura N,
            Miyazawa K, Kwon AH, Kamiyama Y and Okumura T.
  TITLE     Exogenously administered HGF activator augments liver regeneration
            through the production of biologically active HGF
  JOURNAL   Biochem Biophys Res Commun 290 (1), 475-481 (2002)
   PUBMED   11779195
REFERENCE   3  (bases 1 to 2067)
  AUTHORS   Tapper J, Kettunen E, El-Rifai W, Seppala M, Andersson LC and
            Knuutila S.
  TITLE     Changes in gene expression during progression of ovarian carcinoma
  JOURNAL   Cancer Genet Cytogenet 128 (1), 1-6 (2001)
   PUBMED   11454421
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC089871.1.
            
            On Apr 19, 2005 this sequence version replaced XM_341240.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC089871.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760494 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2067
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="14"
                     /map="14q21"
     gene            1..2067
                     /gene="Hgfac"
                     /note="HGF activator"
                     /db_xref="GeneID:58947"
                     /db_xref="RGD:70909"
     exon            1..119
                     /gene="Hgfac"
                     /inference="alignment:Splign:2.1.0"
     CDS             12..1973
                     /gene="Hgfac"
                     /note="hepatocyte growth factor activator"
                     /codon_start=1
                     /product="hepatocyte growth factor activator precursor"
                     /protein_id="NP_445772.1"
                     /db_xref="GeneID:58947"
                     /db_xref="RGD:70909"
                     /translation="MRQRAWLPSVSSRPCPFLLLLLLLVVPRVAQPQAGRNHTEPPGP
                     NVTATRMTPMIPATSGNFSTSIGSDPEGEAETEGPQSERYLLSSSSSPLGGQVLTESG
                     QPCRFPFRYGGRMLHSCSSEGSAYRKWCATTHNYDRDRAWGYCAEATLPVEGPAVLDP
                     CASGPCLNGGTCSSTQDHVSYHCACPLAFTGKDCGTEKCFDETRYEYFEVGDHWARVS
                     EGHVEQCSCIEGQARCEDTHHTACLSSPCLNGGTCHLIVGTGTSICACPLGYAGRFCN
                     IVPTERCFLGNGTEYRGVASTSASGLSCLAWNSDLLYQELHVDSVGAAALLGLGPHAY
                     CRNPDKDERPWCYVVKDSALSWEYCRLAACESLARVHSRIPEVLATLPESTSTARPTC
                     GKRHKKRTFLRPRIIGGSSSLPGSHPWLAAIYIGNGFCAGSLVHTCWVVSAAHCFSSS
                     PPRDSITVVLGQHFFNRTTDVTQTFAIEKYVPYTLYSVFNPNDHDLVLIRLKKKGERC
                     AVRSQFVQPICLPEAGSSFPTGHKCQIAGWGHMDENVSGYSNSLLEALVPLVADHKCS
                     SPEVYGADISPNMLCAGYFDCKSDACQGDSGGPLVCEKNGVAYLYGIISWGDGCGRLN
                     KPGVYTRVSNYVDWINDRIRPPKRPAAAS"
     exon            120..300
                     /gene="Hgfac"
                     /inference="alignment:Splign:2.1.0"
     exon            301..397
                     /gene="Hgfac"
                     /inference="alignment:Splign:2.1.0"
     exon            398..477
                     /gene="Hgfac"
                     /inference="alignment:Splign:2.1.0"
     exon            478..600
                     /gene="Hgfac"
                     /inference="alignment:Splign:2.1.0"
     exon            601..732
                     /gene="Hgfac"
                     /inference="alignment:Splign:2.1.0"
     exon            733..843
                     /gene="Hgfac"
                     /inference="alignment:Splign:2.1.0"
     exon            844..1018
                     /gene="Hgfac"
                     /inference="alignment:Splign:2.1.0"
     exon            1019..1104
                     /gene="Hgfac"
                     /inference="alignment:Splign:2.1.0"
     exon            1105..1360
                     /gene="Hgfac"
                     /inference="alignment:Splign:2.1.0"
     exon            1361..1500
                     /gene="Hgfac"
                     /inference="alignment:Splign:2.1.0"
     exon            1501..1641
                     /gene="Hgfac"
                     /inference="alignment:Splign:2.1.0"
     exon            1642..1790
                     /gene="Hgfac"
                     /inference="alignment:Splign:2.1.0"
     exon            1791..2042
                     /gene="Hgfac"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 caggaggagc catgcggcaa cgggcctggc tccctagtgt ctcttccagg ccatgtccct
       61 tcctgctgct cctgctactg ctggtggtgc ctcgggtggc ccagccccag gctggcagga
      121 accacacaga gcccccagga cctaatgtta cagccacccg catgactccc atgatccctg
      181 cgacctctgg caacttcagc acctcaatag gaagtgatcc agagggagag gcagagaccg
      241 agggacccca aagtgagagg tatctccttt cctccagcag cagccctctc gggggccaag
      301 tgctcaccga gtccggacag ccgtgcaggt tccctttccg ctatggtggc cgcatgctgc
      361 actcctgttc ctctgaggga agtgcctaca ggaagtggtg tgctacgaca cacaactacg
      421 acagagaccg ggcctggggc tactgtgcag aggccaccct gcctgtggaa ggcccagctg
      481 tccttgatcc ttgtgcctct gggccctgcc tcaatggagg cacatgttcc agtacccagg
      541 accatgtgtc ctaccactgt gcttgcccgc tggccttcac aggcaaggac tgtggcacag
      601 agaagtgctt tgatgaaaca cgctacgagt attttgaggt gggcgaccac tgggcccgtg
      661 tgagcgaggg acatgtggag cagtgcagct gtatcgaggg gcaggcccgg tgtgaagaca
      721 cccaccacac agcttgcctg agcagcccat gtctgaatgg aggaacctgc cacctgattg
      781 tgggcacagg gaccagcatc tgcgcctgcc cgttgggtta tgctgggcgg ttctgcaaca
      841 ttgttcccac tgagcgctgc ttcctgggca atggaacaga gtaccgcggt gtggccagca
      901 cctctgcctc gggcctgagc tgcctggcct ggaattccga cctgctctac caggagctcc
      961 atgtagactc agtgggtgct gctgccctgc ttggcctggg ccctcatgct tactgccgga
     1021 acccagacaa ggacgagagg ccttggtgct atgtggtgaa ggacagcgcg ctgtcatggg
     1081 agtattgtcg cctggcagct tgtgaatcct tggccagagt ccattcccga atcccggagg
     1141 tcctagcgac cctgcctgag tcgacctcaa ctgcacgtcc gacctgtggc aagaggcaca
     1201 agaagaggac attcttgagg ccacgcatca ttggtggctc atcgtctttg cccggctcac
     1261 acccctggct ggccgccatc tacattggga acggcttctg tgctgggagc ctcgtccaca
     1321 cctgctgggt agtgtctgca gcccactgct tctccagcag cccccccagg gacagcatca
     1381 cagtggtact gggtcagcac ttcttcaacc gcacgacgga tgtgacacag acctttgcca
     1441 ttgagaagta cgtgccctac accctctact cggtgttcaa ccccaacgac catgaccttg
     1501 tcttgatccg gctgaagaag aagggggagc gctgtgctgt ccgctcccag ttcgttcagc
     1561 ccatctgcct ccctgaggca ggcagctctt tccctacagg acacaagtgt cagattgcag
     1621 gctggggtca catggacgag aatgtgagtg gatattccaa ctccctgctg gaggcactgg
     1681 tccccctggt tgctgaccac aagtgcagca gccctgaggt gtatggtgcc gacatcagcc
     1741 ccaacatgct ctgtgctgga tactttgact gcaagtctga tgcctgccag ggggactcgg
     1801 gtgggccctt ggtctgtgag aagaatggtg tggcttacct gtatggcatc atcagctggg
     1861 gtgatggctg tgggaggctc aacaagccag gagtctacac ccgtgtgtcc aattatgtgg
     1921 actggatcaa cgaccgcatt cggccaccca agcgacctgc agctgcctcc tgaaccatgg
     1981 tctccaagga gaggatgctc acaattccct ttctactacc aataataaaa gtgttgccta
     2041 gaaaaaaaaa aaaaaaaaaa aaaaaaa
//
