LOCUS       XM_039088492            1545 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus homogentisate 1, 2-dioxygenase (Hgd),
            transcript variant X1, mRNA.
ACCESSION   XM_039088492
VERSION     XM_039088492.1
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051346.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1545
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="11"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..1545
                     /gene="Hgd"
                     /note="homogentisate 1, 2-dioxygenase; Derived by
                     automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 9 ESTs, 1 long SRA read, and 98% coverage of the
                     annotated genomic feature by RNAseq alignments, including
                     5 samples with support for all annotated introns"
                     /db_xref="GeneID:360719"
                     /db_xref="RGD:1308757"
     CDS             435..1352
                     /gene="Hgd"
                     /codon_start=1
                     /product="homogentisate 1,2-dioxygenase isoform X1"
                     /protein_id="XP_038944420.1"
                     /db_xref="GeneID:360719"
                     /db_xref="RGD:1308757"
                     /translation="MGLLCISSCVTPPWRTVPQKGKLLIYTEFGKMFLQPNEICVIQR
                     GMRFSVDVFEETRGYILEVYGVHFELPDLGPIGANGLANPRDFLIPVAWYEDRQVPGG
                     FTVINKYQGKLFASKQDVSPFNVVAWHGNYTPYKYNLENFMVINAVAFDHADPSIFTV
                     LTAKSLRPGVAIADFVIFPPRWGVADKTFRPPYYHRNCMSEFMGLIKGHYEAKQGGFL
                     PGGGSLHSAMTPHGPDADCFEKASKAKLEPERIADGTMAFMFESSLSLAVTKWGLKTC
                     GCLDEDYYKCWEPLQAHFTPTSRSPTEPK"
ORIGIN      
        1 cattcgtacc tcagctcctt ggcctgagtt tccttccagc agaagggaaa tggcagagtt
       61 aaagtacatt tctggatttg ggaatgagtg tgcttcagag gatcctcgct gcccaggctc
      121 cctgccgaaa ggacagaata atcctcagat ctgcccctac aatctctacg ctgagcagct
      181 ctcgggatcg gccttcactt gtccacggaa caccaataag agaagctggc tatacagaat
      241 tctcccttca gtttctcaca agccatttgc gtccattgac caaggccaca tcaaccacaa
      301 ctgggatgaa gttggccctg atcctaacca gcttagatgg aaaccgtttg agattccaaa
      361 agcatgtcag aagaaagtgg actttgtgag tggcttgcac accttatgtg gagcaggaga
      421 catcaggtct aacaatgggc ttgctgtgca tatcttcctg tgtaactcct ccatggagaa
      481 cagttcccca gaaagggaag cttctcatct acacagagtt tggcaagatg ttcctgcagc
      541 ccaatgagat ctgcgtcatt cagagaggaa tgagattcag tgttgatgtc ttcgaggaga
      601 ccaggggtta catcctggaa gtctacggtg tccacttcga gctacctgac ctaggaccca
      661 tcggagcaaa tggcttggcc aatcctcgag atttcttgat ccctgttgct tggtatgaag
      721 atcgtcaagt gccgggtggt ttcaccgtga ttaataaata ccagggaaag ctgtttgctt
      781 ccaaacagga tgtctccccc ttcaatgtcg tggcctggca tggaaactat acaccctaca
      841 agtacaacct cgagaacttc atggtcatca atgcggtggc ctttgaccat gcagatcctt
      901 ccattttcac agtgctgacc gccaagtctc tccgacctgg agtggccatt gctgactttg
      961 tgatcttccc acctcggtgg ggggttgcag ataaaacctt cagacctcct tattaccaca
     1021 ggaactgcat gagtgagttc atgggactca tcaaaggtca ctatgaggca aagcaaggtg
     1081 gattcctgcc agggggaggc agtctgcaca gtgccatgac ccctcatggc cccgacgcag
     1141 actgctttga gaaggccagc aaggccaaac tggaacctga gaggatagca gacggcacca
     1201 tggcatttat gtttgaatct tccttgagtt tggcagtcac caagtgggga ctcaagacct
     1261 gtggttgttt ggatgaggac tactacaaat gctgggagcc tctccaggcc cacttcaccc
     1321 ccacttccag gagcccaaca gagcctaagt gagaccggag ccctctacag taattgagaa
     1381 caggctcgca tggcttcctc gagagcctca cacctctggc gctatcaggg actgcgatta
     1441 gaatgagatt tactcatcat attcaagaaa ctcacaatga ctgtggacat gaattcagaa
     1501 gtgcctatgg ctctctaatc catcaataaa tttgtgtttc tgtgg
//
