LOCUS       NM_001037655            1693 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus HEN methyltransferase 1 (Henmt1), mRNA.
ACCESSION   NM_001037655 XM_345272
VERSION     NM_001037655.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1693)
  AUTHORS   Kirino,Y. and Mourelatos,Z.
  TITLE     The mouse homolog of HEN1 is a potential methylase for
            Piwi-interacting RNAs
  JOURNAL   RNA 13 (9), 1397-1401 (2007)
   PUBMED   17652135
REFERENCE   2  (bases 1 to 1693)
  AUTHORS   Kirino,Y. and Mourelatos,Z.
  TITLE     2'-O-methyl modification in mouse piRNAs and its methylase
  JOURNAL   Nucleic Acids Symp Ser (Oxf) (51), 417-418 (2007)
   PUBMED   18029764
REFERENCE   3  (bases 1 to 1693)
  AUTHORS   Florea,L., Di Francesco,V., Miller,J., Turner,R., Yao,A.,
            Harris,M., Walenz,B., Mobarry,C., Merkulov,G.V., Charlab,R.,
            Dew,I., Deng,Z., Istrail,S., Li,P. and Sutton,G.
  TITLE     Gene and alternative splicing annotation with AIR
  JOURNAL   Genome Res 15 (1), 54-66 (2005)
   PUBMED   15632090
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC107926.1.
            
            On Dec 9, 2005 this sequence version replaced XM_345272.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC107926.1, CK600750.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132294, SAMD00132297
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1693              BC107926.1         1-1693
FEATURES             Location/Qualifiers
     source          1..1693
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="2"
                     /map="2q41"
     gene            1..1693
                     /gene="Henmt1"
                     /gene_synonym="RGD1306230"
                     /note="HEN methyltransferase 1"
                     /db_xref="GeneID:100363095"
                     /db_xref="RGD:1306230"
     exon            1..90
                     /gene="Henmt1"
                     /gene_synonym="RGD1306230"
                     /inference="alignment:Splign:2.1.0"
     CDS             49..1251
                     /gene="Henmt1"
                     /gene_synonym="RGD1306230"
                     /EC_number="2.1.1.386"
                     /note="HEN1 methyltransferase homolog 1"
                     /codon_start=1
                     /product="small RNA 2'-O-methyltransferase"
                     /protein_id="NP_001032744.2"
                     /db_xref="GeneID:100363095"
                     /db_xref="RGD:1306230"
                     /translation="MEVENQMETAENIPCSMLGDNFKEVCAEKVIRFRPPLYKQRYQF
                     VRDLVDRHEPKKVADLGCGDTKLLKLLKIYPCIQLLVGVDINEEKLHSNGHRLSPYLG
                     EFVKPRDLDLTVTLYHGSVVERDSRLLGFDLITCIELIEHLDSDDLARFPEVVFGYLS
                     PAMVVISTPNAEFNPLFPTVTLRDADHKFEWSRMEFQTWASQVANCYNYCVEFTGVGT
                     PPAGSEHVGYCTQIGVFRKNGGKLSEPSASQQRDQHVYKAVYTTSYPSLQQEKVLKFV
                     LVGELLIQVDRLRLRHQRMLREQEKERGPKPWYTDSSPAPHLLLGAVFTEAEKARIEN
                     SPKPFCEGEKFYIPLQRLLTYPKLHRLCADEDRMRSLIADSVCLSSDGSAVVVDLHNS
                     WDYRPEDN"
     exon            91..216
                     /gene="Henmt1"
                     /gene_synonym="RGD1306230"
                     /inference="alignment:Splign:2.1.0"
     exon            217..329
                     /gene="Henmt1"
                     /gene_synonym="RGD1306230"
                     /inference="alignment:Splign:2.1.0"
     exon            330..464
                     /gene="Henmt1"
                     /gene_synonym="RGD1306230"
                     /inference="alignment:Splign:2.1.0"
     exon            465..644
                     /gene="Henmt1"
                     /gene_synonym="RGD1306230"
                     /inference="alignment:Splign:2.1.0"
     exon            645..822
                     /gene="Henmt1"
                     /gene_synonym="RGD1306230"
                     /inference="alignment:Splign:2.1.0"
     exon            823..1672
                     /gene="Henmt1"
                     /gene_synonym="RGD1306230"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ctgatacaga gcccagagga taaatctgga tttttacttt ttgtcacaat ggaagtcgaa
       61 aaccaaatgg aaacggcaga aaacataccg tgcagtatgc ttggtgataa tttcaaagaa
      121 gtttgtgcag agaaggtaat taggttcagg ccgccattat acaaacaacg gtaccagttc
      181 gttagagatt tagtggatcg ccatgaaccc aagaaggttg cagacctggg atgtggtgat
      241 accaagctcc taaagctgct aaaaatctac ccatgcattc agctgcttgt tggggtggat
      301 atcaatgagg aaaaattgca ttcaaatggg catcgcttgt ctccctattt gggggagttc
      361 gtaaaacccc gagatctaga tttgactgtc accttgtatc atggctctgt tgtggagaga
      421 gactcgcgct tgcttggatt cgatttgata acatgcattg aattaataga acatctggat
      481 tcagatgatc tggccagatt tcctgaagtg gtttttggat acctgtcacc agccatggtt
      541 gtcatcagca caccaaatgc tgagttcaac cccctgtttc ctacagtgac cctgagggac
      601 gccgatcata agtttgagtg gagcagaatg gagtttcaga cctgggcttc acaggtggca
      661 aactgctaca attactgtgt ggagttcact ggggtgggga cacccccagc tggatctgag
      721 catgttggat attgcaccca gataggtgtc tttaggaaaa acggtgggaa gctctctgag
      781 ccctctgctt cccagcagcg tgaccagcat gtttataaag ctgtttatac aacctcctac
      841 ccgagtttac agcaggagaa ggtgctcaag tttgtactgg ttggggaact cctgatacaa
      901 gtggaccgcc tgaggctgag acaccagaga atgctgcggg aacaggagaa ggagcggggc
      961 cctaagccct ggtacacgga ctcctcccca gccccccacc tactgttggg agcagtcttc
     1021 acagaggccg agaaggccag gatagaaaat tctcccaaac ccttctgtga aggagagaag
     1081 ttttacatac ccctgcagag actgctcact taccccaaac tgcaccggct gtgtgctgac
     1141 gaagacagga tgcggtccct catcgctgac tcggtgtgct taagcagtga tggttccgca
     1201 gtcgtggttg acctccataa ttcttgggat tatcggcctg aggataactg agccatccgg
     1261 atttcctgaa gctcggacac tggctgatag ttgggttcgt ttagaattcg cacttttttt
     1321 gttttagtgg tgctgggact caaacccttg ctcatggtaa gcaagcactc tgcctctcgg
     1381 ctacatcctc agccccagaa tttaagcttt gtacagtcat cattcaagaa gtgtttcgag
     1441 agttacacag atcgggtcct gatctggatg gcagctctgc ctgacacaca gactgctctt
     1501 gggcttaacc aaaccaagtt gctttccttt aaaattagat ttttttttaa aaattttttt
     1561 ggtgtttaca acaatataga aattggatgt ggtaatgtgt taattttgtc ctcacccata
     1621 ttttggtgtt agagccgtat gttgtatgtg acattaaaac atttaaatgt aaaaaaaaaa
     1681 aaaaaaaaaa aaa
//
