LOCUS       NM_001106853            1553 bp    mRNA    linear   ROD 24-JAN-2025
DEFINITION  Rattus norvegicus HemK methyltransferase family member 1 (Hemk1),
            mRNA.
ACCESSION   NM_001106853 XM_001074150 XM_217259
VERSION     NM_001106853.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1553)
  AUTHORS   Morgenstern,M., Peikert,C.D., Lubbert,P., Suppanz,I., Klemm,C.,
            Alka,O., Steiert,C., Naumenko,N., Schendzielorz,A., Melchionda,L.,
            Muhlhauser,W.W.D., Knapp,B., Busch,J.D., Stiller,S.B.,
            Dannenmaier,S., Lindau,C., Licheva,M., Eickhorst,C., Galbusera,R.,
            Zerbes,R.M., Ryan,M.T., Kraft,C., Kozjak-Pavlovic,V., Drepper,F.,
            Dennerlein,S., Oeljeklaus,S., Pfanner,N., Wiedemann,N. and
            Warscheid,B.
  TITLE     Quantitative high-confidence human mitochondrial proteome and its
            dynamics in cellular context
  JOURNAL   Cell Metab 33 (12), 2464-2483 (2021)
   PUBMED   34800366
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473954.2.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_001074150.1, XM_217259.4.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC161944.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMD00132261,
                                           SAMD00132262 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: inferred from homology
            RefSeq Select criteria             :: based on conservation,
                                                  expression, longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1553
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="8"
                     /map="8q32"
     gene            1..1553
                     /gene="Hemk1"
                     /gene_synonym="RGD1308293"
                     /note="HemK methyltransferase family member 1"
                     /db_xref="GeneID:300989"
                     /db_xref="RGD:1308293"
     exon            1..36
                     /gene="Hemk1"
                     /gene_synonym="RGD1308293"
                     /inference="alignment:Splign:2.1.0"
     exon            37..416
                     /gene="Hemk1"
                     /gene_synonym="RGD1308293"
                     /inference="alignment:Splign:2.1.0"
     CDS             186..1208
                     /gene="Hemk1"
                     /gene_synonym="RGD1308293"
                     /EC_number="2.1.1.297"
                     /codon_start=1
                     /product="MTRF1L release factor glutamine
                     methyltransferase"
                     /protein_id="NP_001100323.1"
                     /db_xref="GeneID:300989"
                     /db_xref="RGD:1308293"
                     /translation="MKFWGQILWTLLSGPRGRRGAPQGWAFNSWKTYSSPAGLSSATG
                     IVNHWTRVFEERGIPEARESSEYIVAHVLGAKTFQSLRPALWTKPLTPQQLECIQELC
                     NHRLQRMPVQYILGEWDFQGLNLKMAPPVFIPRPETEELVEWVLEEVAQRPPAVRAQD
                     GPLILEVGCGSGAIALSLLSQLPKTQVIAVDKEEAAVSLTLENAQRLQLQDRIRIIHL
                     DITSEGCCTHLLPWGPMDLVVSNPPYIFRKDMEQLAPEIRSYEDLVALDGGDEGMDII
                     THILTLAPWLLNASGSIFLEVDPRHPELVSSWLQSQPDLHLSLVGVREDFCGRPRFLH
                     VQKSAP"
     exon            417..508
                     /gene="Hemk1"
                     /gene_synonym="RGD1308293"
                     /inference="alignment:Splign:2.1.0"
     exon            509..602
                     /gene="Hemk1"
                     /gene_synonym="RGD1308293"
                     /inference="alignment:Splign:2.1.0"
     exon            603..737
                     /gene="Hemk1"
                     /gene_synonym="RGD1308293"
                     /inference="alignment:Splign:2.1.0"
     exon            738..802
                     /gene="Hemk1"
                     /gene_synonym="RGD1308293"
                     /inference="alignment:Splign:2.1.0"
     exon            803..852
                     /gene="Hemk1"
                     /gene_synonym="RGD1308293"
                     /inference="alignment:Splign:2.1.0"
     exon            853..961
                     /gene="Hemk1"
                     /gene_synonym="RGD1308293"
                     /inference="alignment:Splign:2.1.0"
     exon            962..1057
                     /gene="Hemk1"
                     /gene_synonym="RGD1308293"
                     /inference="alignment:Splign:2.1.0"
     exon            1058..1171
                     /gene="Hemk1"
                     /gene_synonym="RGD1308293"
                     /inference="alignment:Splign:2.1.0"
     exon            1172..1553
                     /gene="Hemk1"
                     /gene_synonym="RGD1308293"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tgtgtgggca gagcaagcgt gcatgccctc ttgcaggttg acagcaacat cttagaaaca
       61 aaacgatgga gaactggaac ccatgactga ttcttcttca cccagctcag ggatcattcc
      121 cagcccctac ctcagtgact gatagcacaa gagagactca ggagcttgga aagctttctc
      181 caagaatgaa gttctgggga caaatacttt ggacccttct atctggtccc cgaggaagga
      241 ggggagcccc ccagggctgg gcctttaact catggaagac ttattcatct ccagctgggc
      301 tgtcgagtgc cacagggata gtcaaccact ggacacgggt ctttgaggaa agaggcatcc
      361 cagaggcccg ggaatccagt gagtacatcg tggctcatgt ccttggagcc aaaacatttc
      421 agagcctgag accagcactt tggaccaaac cattgacccc tcaacagctg gagtgcatcc
      481 aggagctgtg taaccataga ttacaaagga tgccggtgca gtatatcctt ggggaatggg
      541 actttcaggg gctcaatctg aagatggcac ccccagtgtt cattcctcgg ccagagacag
      601 aagaactggt tgaatgggtt ttagaggaag tggcccagag gccccctgca gtgagagccc
      661 aagatggtcc cctcattctg gaggtgggct gtggatcagg agccattgct ctcagcctgc
      721 tgagccagct ccctaagact caagtcattg ctgtggataa ggaagaagct gcagtgagtc
      781 tgacccttga gaatgctcag aggcttcagc tgcaggacag gattcggatt atccaccttg
      841 atataacctc agaggggtgc tgcacacacc tcttaccctg gggccccatg gacttggtgg
      901 tgagcaaccc tccctacatc ttccgcaagg acatggaaca gctggctccc gagatccgca
      961 gttacgaaga tctggtggca ctggatggtg gtgacgaagg catggacatc atcacccaca
     1021 tcttgacctt ggcaccctgg ctcttgaatg cctctggaag catcttttta gaagtggacc
     1081 caagacaccc agagcttgtc agcagttggc ttcagagcca gcctgacctg caccttagtc
     1141 ttgtgggtgt ccgtgaagac ttctgcggga gaccccggtt cctgcatgtc cagaagtctg
     1201 caccatagtg tggctactct gtgaacacct ggccaggatg ctagcctgct gggtgcctga
     1261 ctcaccctgc atggagtgct gcccaggggg aggtgtacaa cgctttcctg aacccctggc
     1321 acggcccatg gttctgtgat tccccatcat ggatatttct aggagactca gaaacacaga
     1381 tggagagttc ttctgggtca gcaaagaaca gagactcaag agctgggttt ccagccgagc
     1441 tctgtcacct cagtgtagca ggctacttgg tattcctctt ggtgaaattg ctgtgtagat
     1501 gttgggaagt gtggcaagta aggtattgag agagcaataa atggtgaacc agt
//
