LOCUS       NM_001105848            6193 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus helicase with zinc finger (Helz), mRNA.
ACCESSION   NM_001105848 XM_001081620 XM_001081621 XM_001081622 XM_001081623
            XM_237808
VERSION     NM_001105848.2
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 6193)
  AUTHORS   Baltz,A.G., Munschauer,M., Schwanhausser,B., Vasile,A.,
            Murakawa,Y., Schueler,M., Youngs,N., Penfold-Brown,D., Drew,K.,
            Milek,M., Wyler,E., Bonneau,R., Selbach,M., Dieterich,C. and
            Landthaler,M.
  TITLE     The mRNA-bound proteome and its global occupancy profile on
            protein-coding transcripts
  JOURNAL   Mol Cell 46 (5), 674-690 (2012)
   PUBMED   22681889
REFERENCE   2  (bases 1 to 6193)
  AUTHORS   Castello,A., Fischer,B., Eichelbaum,K., Horos,R., Beckmann,B.M.,
            Strein,C., Davey,N.E., Humphreys,D.T., Preiss,T., Steinmetz,L.M.,
            Krijgsveld,J. and Hentze,M.W.
  TITLE     Insights into RNA biology from an atlas of mammalian mRNA-binding
            proteins
  JOURNAL   Cell 149 (6), 1393-1406 (2012)
   PUBMED   22658674
REFERENCE   3  (bases 1 to 6193)
  AUTHORS   Ghosh,D., Lippert,D., Krokhin,O., Cortens,J.P. and Wilkins,J.A.
  TITLE     Defining the membrane proteome of NK cells
  JOURNAL   J Mass Spectrom 45 (1), 1-25 (2010)
   PUBMED   19946888
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000010.1.
            
            On Jan 12, 2008 this sequence version replaced NM_001105848.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMEA5760383,
                              SAMEA5760389 [ECO:0000348]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-56                JAXUCZ010000010.1  93001158-93001213
            57-284              JAXUCZ010000010.1  93025692-93025919
            285-321             JAXUCZ010000010.1  93028793-93028829
            322-446             JAXUCZ010000010.1  93045671-93045795
            447-503             JAXUCZ010000010.1  93047802-93047858
            504-555             JAXUCZ010000010.1  93049798-93049849
            556-631             JAXUCZ010000010.1  93051297-93051372
            632-830             JAXUCZ010000010.1  93053403-93053601
            831-938             JAXUCZ010000010.1  93054015-93054122
            939-1236            JAXUCZ010000010.1  93055296-93055593
            1237-1504           JAXUCZ010000010.1  93064993-93065260
            1505-1838           JAXUCZ010000010.1  93071873-93072206
            1839-1969           JAXUCZ010000010.1  93072983-93073113
            1970-2149           JAXUCZ010000010.1  93078093-93078272
            2150-2254           JAXUCZ010000010.1  93078920-93079024
            2255-2433           JAXUCZ010000010.1  93084352-93084530
            2434-2552           JAXUCZ010000010.1  93086973-93087091
            2553-2698           JAXUCZ010000010.1  93088159-93088304
            2699-2846           JAXUCZ010000010.1  93089733-93089880
            2847-3030           JAXUCZ010000010.1  93098073-93098256
            3031-3259           JAXUCZ010000010.1  93100661-93100889
            3260-3464           JAXUCZ010000010.1  93107788-93107992
            3465-3516           JAXUCZ010000010.1  93112591-93112642
            3517-3707           JAXUCZ010000010.1  93113386-93113576
            3708-3915           JAXUCZ010000010.1  93115154-93115361
            3916-3995           JAXUCZ010000010.1  93117289-93117368
            3996-4629           JAXUCZ010000010.1  93121189-93121822
            4630-4864           JAXUCZ010000010.1  93122408-93122642
            4865-5381           JAXUCZ010000010.1  93123790-93124306
            5382-5634           JAXUCZ010000010.1  93136292-93136544
            5635-6193           JAXUCZ010000010.1  93137459-93138017
FEATURES             Location/Qualifiers
     source          1..6193
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="10"
                     /map="10q32.1"
     gene            1..6193
                     /gene="Helz"
                     /note="helicase with zinc finger"
                     /db_xref="GeneID:287773"
                     /db_xref="RGD:1307049"
     exon            1..56
                     /gene="Helz"
                     /inference="alignment:Splign:2.1.0"
     exon            57..284
                     /gene="Helz"
                     /inference="alignment:Splign:2.1.0"
     CDS             75..5969
                     /gene="Helz"
                     /note="helicase with zinc finger domain"
                     /codon_start=1
                     /product="probable helicase with zinc finger domain"
                     /protein_id="NP_001099318.2"
                     /db_xref="GeneID:287773"
                     /db_xref="RGD:1307049"
                     /translation="MEDRRAERSCEQACASLQRQDYDMALQHCTDALLSLGQYSMTDF
                     AGPCPVEIERIKIESLLYRIASFLQLKNYGQADEDCRHVLGEGLAKGESAFRAVLCCM
                     QLKGKLQPVSSILAQSLSGESLNGMVTKDLTRLKTLLAETETATSNAPSGCHVEDLDE
                     GSCNGWHFRPPPRGITSSEEYTLCKRFLEQGICRYGAQCTSAHSQEELAEWQKRYASR
                     LIKLKQQSENKQLSGSYMETLIEKWMSSLSPEKVLSECLEGVQVEHSPDLSVTVNTKK
                     SHQTWTFALTCKPARMLCRVALLYDAHRPHFSIIAISAGDSTAQVSQEVPENCQEWIG
                     GEMAQNGLDHYVYKVGIAFNTEIFGTFRQTIVFDFGLEPVLMQRVMIDAASTEDLEYL
                     MHAKQQLVTTARRWEPSSKTIVDFEPNETTDWEKSLLIRYQIPLSADQLFTQSVLDKS
                     LTKTNYQSRLHDLLYIEEIAQYKEVSRFNLKVQLQILASFMLTGVSGGAKYAQNGQLF
                     GRFKLTETLSEDTLAGRLVMTRVNAVYLLPVPKEKLVQSQGTKEKVYEATIEEKTKDY
                     VFLRISRECCEELSLRPDCDTQVELQFQLNRLPLCEMHYALDRIKDNGVLFPDISMTP
                     TIPWSPNRQWDEQLDPRLNAKQKEAVLAITTPLCIQLPPVLIIGPYGTGKTFTLAQAV
                     KHILQQQETSRILICTHSNSAADLYIKDYLHPYVEAGNAQARPLRVYFRNRWVKTVHP
                     VVHQYCLISSAHSTFQMPQKEDILKHRVVVVTLNTSQYLCQLDLEPGFFTHILLDEAA
                     QAMECETIMPLALATKNTRIVLAGDHMQLSPFVYSEFARERNLHVSLLDRLYEHYPAE
                     FPCRILLCENYRSHEAIINYTSELFYEGKLMASGKQPAHKDFYPLTFFTARGEDVQEK
                     NSTAFYNNAEVFEVVERVEELRRKWPVAWGKLDDGSIGVVTPYADQVFRIRAELRKKR
                     LSDVNVERVLNVQGKQFRVLFLSTVRTRHTCKHKQTPIKKKEQLLEDSTEDLDYGFLS
                     NYKLLNTAITRAQSLVAVVGDPVALCSIGRCRKFWERFIALCHENHSLHGITFEQIKA
                     QLEALELKKTYVLNPLAPEFIPRAFRLQHSGNSSRQQQSPPKVKSLHHPQNDHFQNDG
                     IVQPNPSVLIGNPIRAYTPPPPLGPHPNLGKSPSPVQRIDPHTGTSILYVPAVYGGNV
                     VMSVPLPVPWTGYQGRFAVDPRIITHQAAMAYNMNLLHTHGRGSPIPYGLGHHPPVNL
                     GQPQNQHAEKDQQEQNRNGKTDTNNPGPEINKIRTPEKKPTEPKQIDLESNPQNRSPE
                     SRPGVVYSNTKFPRKDNLNPRHINLPLPAPHTQYAIPSRHFHPLPQLPRPPFPISQQH
                     TLLNQQQNNLPEQPNQMTPQPNQVAPQPNQMAPQPNQMAPQPNQVVQQQNQAPPQAPQ
                     PAPQLSPAFQAGPTNAFFNNAVAHRPQSPAAEAVGPEQQVPPGLSDGHSPLRAITQPG
                     PILASPLNNFVDESSPGLPIEEALDRVHGSVALETLRQQQARLQQWSEHHAYLSQGGI
                     PYSHHHHPHLAHLPQTPISLHQPPVRAEWKVAGRADDETETTFSRFQDLLRELSHRDQ
                     GDTGELAEMPPPQSRLLQYRQVQPRSPPAVPSPPSSTDHSSHFANFNDNSRDIEVANS
                     PAFPQRLPPQLFGPPYSLQSEHLAPPPLKYLAPEGAWNFANLQQNHLIGPGFPYGLPP
                     LPPRPPQNPFIHIQNHQHAVGQEPFHPLPSRAVSSSSLPSLEEYEPRGPGRPLYQRRI
                     SSGAAQPCVEEASTPQDSLAQGKEPQDHSNPPGFGFPAPESWANTTSSAPYQNIPCNG
                     SSRTSQPRELIVPPKTVKPPEDQLKPDSGEVSSSFNYSVLQHLGQFPPLMPNKQIAES
                     ANSSSQQSPAGSKPAMSYASALRAPPKPRPPPEQAKKGSDPLSLFQELSLGSSPGSNG
                     FYSYFK"
     exon            285..321
                     /gene="Helz"
                     /inference="alignment:Splign:2.1.0"
     exon            322..446
                     /gene="Helz"
                     /inference="alignment:Splign:2.1.0"
     exon            447..503
                     /gene="Helz"
                     /inference="alignment:Splign:2.1.0"
     exon            504..555
                     /gene="Helz"
                     /inference="alignment:Splign:2.1.0"
     exon            556..631
                     /gene="Helz"
                     /inference="alignment:Splign:2.1.0"
     exon            632..830
                     /gene="Helz"
                     /inference="alignment:Splign:2.1.0"
     exon            831..938
                     /gene="Helz"
                     /inference="alignment:Splign:2.1.0"
     exon            939..1236
                     /gene="Helz"
                     /inference="alignment:Splign:2.1.0"
     exon            1237..1504
                     /gene="Helz"
                     /inference="alignment:Splign:2.1.0"
     exon            1505..1838
                     /gene="Helz"
                     /inference="alignment:Splign:2.1.0"
     exon            1839..1969
                     /gene="Helz"
                     /inference="alignment:Splign:2.1.0"
     exon            1970..2149
                     /gene="Helz"
                     /inference="alignment:Splign:2.1.0"
     exon            2150..2254
                     /gene="Helz"
                     /inference="alignment:Splign:2.1.0"
     exon            2255..2433
                     /gene="Helz"
                     /inference="alignment:Splign:2.1.0"
     exon            2434..2552
                     /gene="Helz"
                     /inference="alignment:Splign:2.1.0"
     exon            2553..2698
                     /gene="Helz"
                     /inference="alignment:Splign:2.1.0"
     exon            2699..2846
                     /gene="Helz"
                     /inference="alignment:Splign:2.1.0"
     exon            2847..3030
                     /gene="Helz"
                     /inference="alignment:Splign:2.1.0"
     exon            3031..3259
                     /gene="Helz"
                     /inference="alignment:Splign:2.1.0"
     exon            3260..3464
                     /gene="Helz"
                     /inference="alignment:Splign:2.1.0"
     exon            3465..3516
                     /gene="Helz"
                     /inference="alignment:Splign:2.1.0"
     exon            3517..3707
                     /gene="Helz"
                     /inference="alignment:Splign:2.1.0"
     exon            3708..3915
                     /gene="Helz"
                     /inference="alignment:Splign:2.1.0"
     exon            3916..3995
                     /gene="Helz"
                     /inference="alignment:Splign:2.1.0"
     exon            3996..4629
                     /gene="Helz"
                     /inference="alignment:Splign:2.1.0"
     exon            4630..4864
                     /gene="Helz"
                     /inference="alignment:Splign:2.1.0"
     exon            4865..5381
                     /gene="Helz"
                     /inference="alignment:Splign:2.1.0"
     exon            5382..5634
                     /gene="Helz"
                     /inference="alignment:Splign:2.1.0"
     exon            5635..6193
                     /gene="Helz"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gaattggatg aagtaattga tcactaatga actacagagc cggtgagatg tacaaggatt
       61 tttgtccctg agtcatggaa gacagaagag ctgaaaggtc atgtgaacaa gcgtgcgcgt
      121 cactgcagag gcaggactat gacatggccc tccagcattg cacagacgcc ctgctctctc
      181 ttggccagta ctccatgaca gacttcgcag ggccgtgccc agtggagatt gagcgcatca
      241 aaatcgagag tcttctgtac agaattgcct cattcttgca gttgaaaaac tacgggcaag
      301 ctgatgaaga ttgtaggcat gtgctggggg aaggactggc caagggagag agcgccttcc
      361 gggcagtgct gtgctgcatg cagctgaagg ggaagctcca gcctgtgtcc tccatccttg
      421 cccagtcact gtcaggggag tctctgaatg ggatggtaac gaaggatttg acaagactca
      481 agacacttct cgcagagaca gagacagcaa caagtaatgc cccctctggc tgtcatgtgg
      541 aagacttaga tgaagggtct tgtaatggtt ggcatttccg cccaccgccc agggggatca
      601 ccagcagtga ggagtacacc ttgtgtaaaa ggtttttaga gcaagggatc tgtaggtacg
      661 gtgcccagtg tacttcagca cattcccagg aagaactagc agaatggcag aagagatatg
      721 cctcgcggct gataaaactg aagcagcaga gtgagaacaa acagctctca ggcagctaca
      781 tggagacctt gatagaaaag tggatgagct cactgtcccc tgagaaagtg cttagcgaat
      841 gcctagaggg agtccaggtg gagcacagcc ctgacctgtc agtcaccgtc aacaccaaaa
      901 agtcccacca gacatggacc tttgctctga cctgtaagcc tgcaagaatg ctgtgtcggg
      961 tagccttgct ctatgatgct catcgtcctc attttagtat cattgccata tctgccggag
     1021 atagtactgc ccaggtatca caagaagtcc ccgagaactg tcaagaatgg ataggaggag
     1081 agatggccca aaatggatta gatcattacg tgtataaagt cgggatagca tttaacacag
     1141 aaatatttgg aacttttcgc caaaccatag ttttcgactt tggattggag ccagtactca
     1201 tgcaaagagt aatgattgac gcagcttcta cagaagatct tgagtacctg atgcatgcca
     1261 agcagcagct ggtaaccaca gccaggcgct gggagccttc ctccaagact attgtagact
     1321 ttgaacctaa cgagactact gattgggaga agagcctttt gatcagatac caaattcctc
     1381 tctctgctga ccagctgttt acacagtccg ttttagacaa atccttgacc aagactaact
     1441 atcagtcacg gctacacgac ctgctttata ttgaggagat agcccagtat aaagaagtca
     1501 gcaggttcaa ccttaaggtg cagctgcaga tcttagcaag cttcatgctc actggagttt
     1561 ctgggggtgc aaagtatgct cagaatggac aactttttgg tcgttttaaa cttactgaaa
     1621 ccctgtctga agacactttg gctggacgac tggtgatgac cagggtcaat gctgtttatt
     1681 tattaccagt ccctaaagag aagctcgtcc agtcccaggg aaccaaagag aaggtttatg
     1741 aagctactat tgaagaaaaa acaaaagact atgtattttt aaggatatcc agggaatgct
     1801 gtgaagagct cagtctgcgg cctgactgtg acacccaggt tgagcttcag tttcagttga
     1861 accgattacc cctctgtgaa atgcattatg cactagacag gattaaggac aatggtgttt
     1921 tgtttccaga catcagtatg actcccacta taccttggag tcccaacaga cagtgggatg
     1981 agcagttgga tcctcgacta aatgcaaagc agaaagaagc tgtgctggcc atcaccactc
     2041 cgctctgcat ccagctgccc cccgttctta tcattggacc ctacgggacg ggtaaaacct
     2101 tcactctggc tcaggccgtc aagcacatac tgcagcagca ggagacgagc aggattctca
     2161 tttgcaccca ttctaatagt gctgctgacc tctacataaa ggattattta catccctatg
     2221 tagaagcagg caatgcccag gcaagacctc tcagggtgta tttccgaaat cgctgggtga
     2281 agactgttca cccggttgtg catcagtact gtttgatctc aagcgcacac tccacctttc
     2341 agatgcccca gaaggaagat attcttaaac atcgagtggt ggtggtcaca ctgaacactt
     2401 cccagtacct ctgccagctg gaccttgaac ctgggttctt cacgcacatt ctgttagatg
     2461 aagctgccca ggccatggag tgtgagacca ttatgcctct agccttagca actaaaaaca
     2521 cacggattgt tttggctggt gaccatatgc agctcagtcc ttttgtttac agcgagtttg
     2581 ccagggagag aaaccttcat gtttcattac ttgatcgact ctacgagcat taccctgccg
     2641 agtttccatg caggatcctc ctctgtgaga actatcgctc ccatgaagct atcatcaact
     2701 atacctctga gctcttctat gagggtaaac tgatggccag tggaaagcag ccagcacaca
     2761 aggacttcta cccactgacg ttctttacag cacgagggga ggacgtccaa gagaagaaca
     2821 gcacggcatt ctataacaat gcagaggtat ttgaagtggt ggagcgtgtg gaagagctaa
     2881 gacggaagtg gccagtggca tgggggaagt tagacgacgg cagcattggt gtggtgacac
     2941 catacgctga tcaggtgttc agaatacgag ctgaacttcg gaagaagagg ctctcggacg
     3001 tgaatgtaga aagggtgctc aatgtccaag gaaagcaatt cagagttctg tttcttagca
     3061 cagtgcgtac acgccacact tgcaagcata agcagacgcc aattaaaaag aaagagcaac
     3121 ttctggaaga ctccaccgag gacttagatt acgggtttct atccaactac aaacttctca
     3181 ataccgccat taccagagca cagtccctgg ttgctgtggt gggcgacccc gttgctctgt
     3241 gctctattgg aaggtgtaga aagttttggg agcggtttat tgccctgtgt catgaaaacc
     3301 acagcttgca cgggatcaca ttcgaacaga tcaaggccca gttagaggct ttagagctca
     3361 agaagactta cgtgttgaac ccactggctc ctgaatttat tccccgggct ttcagactgc
     3421 agcattcagg aaacagtagc agacagcagc agtcaccacc caaggtgaaa agcctccatc
     3481 atccccagaa tgaccatttc cagaatgatg gaattgttca gcccaaccct tccgtactta
     3541 ttggcaatcc tattagagca tatactcctc caccccctct tggaccgcac ccaaacttgg
     3601 ggaaatctcc aagccccgtt caaagaatag accctcacac tgggactagt attctttacg
     3661 ttcctgctgt ctatggaggg aatgtagtta tgtcggtgcc tttacctgtg ccgtggacag
     3721 ggtaccaggg taggtttgca gttgatcctc ggattattac acaccaggca gcgatggcct
     3781 acaatatgaa tttgttacac acacatgggc gtgggtcgcc aatcccttat ggtcttggac
     3841 atcacccacc tgtcaaccta ggccagccac agaatcagca cgcagagaag gatcaacagg
     3901 agcaaaatcg aaacggtaaa actgatacaa ataacccagg acctgaaatt aataagatcc
     3961 gaacaccaga gaaaaaacct acagaaccca aacagattga tttggaatca aatccacaga
     4021 acagaagtcc tgaatcccgt cctggtgttg tttattccaa tactaaattt cctcgaaaag
     4081 ataatctcaa cccaagacac ataaatcttc ctcttcctgc gccacataca cagtatgcaa
     4141 tccctagccg ccattttcat ccgcttcctc agctacccag gccaccattt cccatttccc
     4201 agcagcacac cttattaaat cagcagcaga ataatttgcc tgaacaacca aatcagatga
     4261 cacctcagcc aaatcaggtg gcaccccagc caaatcagat ggcaccccag ccaaatcaga
     4321 tggcacccca gccaaatcag gtggtccagc agcagaacca ggcacctcca caggctccac
     4381 agccagcacc tcaactctct cctgcatttc aggcggggcc caccaatgca tttttcaata
     4441 atgcagttgc tcatcgacca cagtctcctg ctgcagaggc tgtgggtcct gagcagcagg
     4501 tgcctcctgg gctgtccgac ggccacagtc cactgagagc catcacacag cctggcccca
     4561 tcctagcatc acctttgaac aactttgttg atgagagctc tccaggattg cctatagaag
     4621 aagctttgga tcgagtgcat ggaagtgtag ctctggagac actgaggcag cagcaggcac
     4681 ggctacagca gtggagtgag caccatgcct acctgagcca gggtggcatc ccgtattcac
     4741 accatcacca tcctcacctc gcccatcttc cccagactcc cattagcctc caccagccac
     4801 cagtgagagc agagtggaaa gtcgccggca gggctgacga tgaaacagag acaacattct
     4861 caaggtttca agacttactc agagagctgt cccatcggga tcaaggtgac actggagagc
     4921 tagctgaaat gccaccgcct cagtcaagac ttctgcagta cagacaagtg cagcctcgaa
     4981 gcccaccagc agtcccgtcg cccccttcct ctacagacca cagtagccac tttgctaact
     5041 ttaatgacaa cagcagagac atcgaagtag ccaacagccc agcattccca cagcgcctcc
     5101 cacctcagct attcggcccc ccttattcgt tgcaatctga acaccttgcc cctccccctc
     5161 tgaaatacct ggctccggaa ggagcatgga attttgctaa cttgcagcag aatcatttaa
     5221 tagggccggg ctttccctat ggcctacctc cattgcctcc ccggccacca cagaaccctt
     5281 ttatacacat ccagaaccat caacacgctg ttggtcaaga gccatttcac ccactgccat
     5341 ctcgagcagt gtcttcttct tcgctcccca gcctagaaga gtatgagccc agaggacctg
     5401 gtcggccctt gtaccaaaga agaatctcat ctggcgcagc ccagccttgt gtggaagagg
     5461 ccagcactcc ccaagacagc ctggctcagg gcaaagaacc gcaggaccac agtaacccac
     5521 ctgggttcgg cttcccagcc cccgagtcct gggccaacac cacctcatct gccccctacc
     5581 agaacattcc atgcaatgga tccagcagga caagtcagcc cagagagttg atagttccac
     5641 ccaagactgt caaaccccct gaggatcagc tgaagcctga cagtggggag gtgtccagtt
     5701 ccttcaacta ctcggtgctg cagcacctcg gccagttccc acccctcatg cccaacaagc
     5761 agatcgcgga gtctgccaac agcagcagcc agcagagccc ggcagggagc aagcccgcca
     5821 tgtcctatgc cagtgcgcta cgggccccgc ccaagcccag gcctccgccc gagcaggcca
     5881 agaagggcag cgacccactg tccctgttcc aggagctcag cttgggcagc agcccgggaa
     5941 gcaatggctt ctactcctac ttcaagtgac ccggctcgcg ctctcctcag agaatgtgca
     6001 gttcctgttc agtctgcagg attgaggtgg cggctctgtc tgtgtgcagc cctccataac
     6061 gttcactgcg ctctcagtcc ccttgctgct agacctgcgc ctacgtttaa aagtatattc
     6121 cattattttg catttttgat gtgagtcaga attttgacag cttttatgta gaataaaaat
     6181 atttttaaat ttg
//
