LOCUS       NM_001107515            2550 bp    mRNA    linear   ROD 21-MAR-2023
DEFINITION  Rattus norvegicus heme binding protein 2 (Hebp2), mRNA.
ACCESSION   NM_001107515 XM_001072434 XM_218664
VERSION     NM_001107515.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2550)
  AUTHORS   Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta
            R, Wang NS and Knepper MA.
  TITLE     Large-scale proteomics and phosphoproteomics of urinary exosomes
  JOURNAL   J Am Soc Nephrol 20 (2), 363-379 (2009)
   PUBMED   19056867
REFERENCE   2  (bases 1 to 2550)
  AUTHORS   Szigeti A, Bellyei S, Gasz B, Boronkai A, Hocsak E, Minik O, Bognar
            Z, Varbiro G, Sumegi B and Gallyas F Jr.
  TITLE     Induction of necrotic cell death and mitochondrial permeabilization
            by heme binding protein 2/SOUL
  JOURNAL   FEBS Lett 580 (27), 6447-6454 (2006)
   PUBMED   17098234
REFERENCE   3  (bases 1 to 2550)
  AUTHORS   Zylka MJ and Reppert SM.
  TITLE     Discovery of a putative heme-binding protein family (SOUL/HBP) by
            two-tissue suppression subtractive hybridization and database
            searches
  JOURNAL   Brain Res Mol Brain Res 74 (1-2), 175-181 (1999)
   PUBMED   10640688
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JACYVU010000008.1.
            
            [WARNING] On Apr 1, 2024 this sequence was replaced by
            NM_001107515.3.
            
            On Nov 27, 2020 this sequence version replaced NM_001107515.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: CA339565.1, CB584706.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN12840117 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-401               JACYVU010000008.1  11270524-11270924   c
            402-537             JACYVU010000008.1  11269953-11270088   c
            538-718             JACYVU010000008.1  11269072-11269252   c
            719-2550            JACYVU010000008.1  11264129-11265960   c
FEATURES             Location/Qualifiers
     source          1..2550
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1p12"
     gene            1..2550
                     /gene="Hebp2"
                     /note="heme binding protein 2"
                     /db_xref="GeneID:308632"
                     /db_xref="RGD:1311553"
     exon            1..401
                     /gene="Hebp2"
                     /inference="alignment:Splign:2.1.0"
     CDS             306..917
                     /gene="Hebp2"
                     /codon_start=1
                     /product="heme-binding protein 2"
                     /protein_id="NP_001100985.1"
                     /db_xref="GeneID:308632"
                     /db_xref="RGD:1311553"
                     /translation="MAEEPDLGVAEGSEEQAMEMPSWKAPENIDPQPGSYEIRHYGPA
                     KWVSTCVESLDWDSAIQTGFTKLNGYIQGKNEKEMKIKLTAPVMSFVEPGSGPFSEST
                     ITISLYIPSEQQHDPPRPSESDVFIEDRGEMTVFVRSFDGFSSGQKNQEQLLTLANIL
                     REEGKVFNEKVFYTAGYSSPFRLLDRNNEVWLIQRNEPSDEDK"
     exon            402..537
                     /gene="Hebp2"
                     /inference="alignment:Splign:2.1.0"
     exon            538..718
                     /gene="Hebp2"
                     /inference="alignment:Splign:2.1.0"
     exon            719..2550
                     /gene="Hebp2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gagggactct gcagaggacc cgggtgaccc agggccagcc tgcggatcct gatcagtctg
       61 accagaggcg gattctgacc acaccccaca cccctgcaga agggtgtggt tagggctggc
      121 gcaagcccgg ggtgggcact cagctccctt tagatcgcga cgccgccttg tggctcaaac
      181 tgagaatgtc ctagagatcc gcagtaaggg tttcagggcc gtgcgtgcgc cggtggggca
      241 ggtactcaga acaaagtggc cggtggacat agacagggcg cgacccttgc aagctgccct
      301 agcccatggc agaagagcca gacctcgggg tggctgaggg ctcagaggag caggccatgg
      361 agatgccgag ctggaaggct ccagagaaca tagaccccca gccaggaagt tatgagatcc
      421 gacactacgg accagctaag tgggtcagca cttgcgtgga gtctctggac tgggattcag
      481 ccatccaaac tggtttcaca aagttgaatg gctacattca aggcaaaaat gagaaagaga
      541 tgaaaatcaa actgacagct ccggtgatga gcttcgtgga gcccggctca ggtcctttta
      601 gtgagtctac cattaccatt tccctgtata tcccctctga gcagcaacat gatccaccca
      661 ggccttcgga gtcagatgtc ttcattgaag atagaggtga aatgactgtg tttgtgcggt
      721 ctttcgatgg attctccagt ggccaaaaga atcaagagca acttttgacc ttggcaaaca
      781 ttctgaggga agaaggaaaa gtcttcaacg agaaggtctt ttatactgca ggctacagca
      841 gtccgttccg gttacttgac agaaataacg aagtatggct gattcagaga aacgagccct
      901 ccgatgaaga caagtaagga aaggaagatc actggcaggg gcagaccttc tgctgagtgc
      961 agacattgat agcgctccta ggtgacgcat gtcgtgtcct tggcttgagc taccactgta
     1021 taccatgctt attcccagtg tgcctttgta agtagcttta tttagataca gggtataaac
     1081 acaaacccgg aaatgagtca taactcaggt ggcctctatt tccgagagga tccgagacaa
     1141 tgcgtggcat ttccctctca ttggccctag cactgttgtc ttgcctctct acttggactt
     1201 agggcatttg aatgctctcc cttccttata atagcagcga aaatgttaaa aatgtactct
     1261 gtgtggaagt aaaattatgt tggctacaaa aataacctta ccgcctctcc tgttgaattt
     1321 ttccattgga tccatgtctt catccaactg ttgctccctg aacaaagaaa gttcttacct
     1381 taatgcgctg acagaatttg gaggcagaag ataagtttga caagatgatg agacttccta
     1441 tgctacttga caaaaaaaaa aaaaaaaaaa aaaaaaaaaa caaaaaacaa aacaaaacaa
     1501 aaaaacccac acagatacct aattgtaaca ttcgcttgaa tttttaaaga actgtatata
     1561 gtctagtcgt tctagatgta tggaaactct tacgctttcc aaaagtgggt tgctgcaaga
     1621 tcaaggaggt tagaaagcct agcctccttg tattgtttac tcttattctt cagaagatca
     1681 agtcacactc agatccctgg cagctgtcat agaaatggct ctcactctaa ttcagactcc
     1741 cagaacgctg gctctgagag cagagagtag agcaggctag atctcaggaa cctcgtgata
     1801 attaatgccc ctcacaagtg gcatggtttc cacttcgatg tatgcagaga ccacacggtt
     1861 gcttcttgag aaatgaccat gaagtcagct gagggtacaa tagattgcat aaggctaaat
     1921 gatacatgaa atccctccaa cttcaatgtg tctttgtaaa attaaactct ccagaccagt
     1981 ggttctcagt cttcctaatg ctttgataca gttcctcatg ttgtggtgac cctcggccat
     2041 aagattgtct ttcttctgct acttcataac tgtaattttt cttctctttt tgagttgcag
     2101 tatagatatc tgtgttttcc aatggtctta ggcatctcct gtgaaagggt cattcagccc
     2161 caaagggctc atgacccaca ggttgagaac cactgctcta gccacatctg tccccatagt
     2221 tgaagactgt cctgagtatt tcacctggat cttcagtcaa gcttcagaat aatccacagc
     2281 tgagcaccac tgttttgtag aggaagaaac tggggcatgg ggttctcggg caacttttgc
     2341 cccagacaaa actgtaaggg cagaggctga cctggttttt ccattcattc cactctgact
     2401 atggtaataa gcacagaaac ctttaagatg gtcagttttg atacagaaca agctatattt
     2461 ctggttctga aattgttgca gatataagaa tctttaattc tcagcattac ttgcttgagt
     2521 tgcatgttaa tttttttact tttatagcat
//
