LOCUS       NM_001398876            1034 bp    mRNA    linear   ROD 22-SEP-2024
DEFINITION  Rattus norvegicus heme binding protein 1 (Hebp1), transcript
            variant 1, mRNA.
ACCESSION   NM_001398876 XM_006237529
VERSION     NM_001398876.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1034)
  AUTHORS   Morgenstern,M., Peikert,C.D., Lubbert,P., Suppanz,I., Klemm,C.,
            Alka,O., Steiert,C., Naumenko,N., Schendzielorz,A., Melchionda,L.,
            Muhlhauser,W.W.D., Knapp,B., Busch,J.D., Stiller,S.B.,
            Dannenmaier,S., Lindau,C., Licheva,M., Eickhorst,C., Galbusera,R.,
            Zerbes,R.M., Ryan,M.T., Kraft,C., Kozjak-Pavlovic,V., Drepper,F.,
            Dennerlein,S., Oeljeklaus,S., Pfanner,N., Wiedemann,N. and
            Warscheid,B.
  TITLE     Quantitative high-confidence human mitochondrial proteome and its
            dynamics in cellular context
  JOURNAL   Cell Metab 33 (12), 2464-2483 (2021)
   PUBMED   34800366
REFERENCE   2  (bases 1 to 1034)
  AUTHORS   Gonzales,P.A., Pisitkun,T., Hoffert,J.D., Tchapyjnikov,D.,
            Star,R.A., Kleta,R., Wang,N.S. and Knepper,M.A.
  TITLE     Large-scale proteomics and phosphoproteomics of urinary exosomes
  JOURNAL   J Am Soc Nephrol 20 (2), 363-379 (2009)
   PUBMED   19056867
REFERENCE   3  (bases 1 to 1034)
  AUTHORS   Dias,J.S., Macedo,A.L., Ferreira,G.C., Peterson,F.C., Volkman,B.F.
            and Goodfellow,B.J.
  TITLE     The first structure from the SOUL/HBP family of heme-binding
            proteins, murine P22HBP
  JOURNAL   J Biol Chem 281 (42), 31553-31561 (2006)
   PUBMED   16905545
  REMARK    Erratum:[J Biol Chem. 2006 Dec 15;281(50):38966]
REFERENCE   4  (bases 1 to 1034)
  AUTHORS   Mootha,V.K., Bunkenborg,J., Olsen,J.V., Hjerrild,M.,
            Wisniewski,J.R., Stahl,E., Bolouri,M.S., Ray,H.N., Sihag,S.,
            Kamal,M., Patterson,N., Lander,E.S. and Mann,M.
  TITLE     Integrated analysis of protein composition, tissue diversity, and
            gene regulation in mouse mitochondria
  JOURNAL   Cell 115 (5), 629-640 (2003)
   PUBMED   14651853
REFERENCE   5  (bases 1 to 1034)
  AUTHORS   Jacob Blackmon,B., Dailey,T.A., Lianchun,X. and Dailey,H.A.
  TITLE     Characterization of a human and mouse tetrapyrrole-binding protein
  JOURNAL   Arch Biochem Biophys 407 (2), 196-201 (2002)
   PUBMED   12413491
REFERENCE   6  (bases 1 to 1034)
  AUTHORS   Zylka,M.J. and Reppert,S.M.
  TITLE     Discovery of a putative heme-binding protein family (SOUL/HBP) by
            two-tissue suppression subtractive hybridization and database
            searches
  JOURNAL   Brain Res Mol Brain Res 74 (1-2), 175-181 (1999)
   PUBMED   10640688
REFERENCE   7  (bases 1 to 1034)
  AUTHORS   Taketani,S., Adachi,Y., Kohno,H., Ikehara,S., Tokunaga,R. and
            Ishii,T.
  TITLE     Molecular characterization of a newly identified heme-binding
            protein induced during differentiation of urine erythroleukemia
            cells
  JOURNAL   J Biol Chem 273 (47), 31388-31394 (1998)
   PUBMED   9813049
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000004.1.
            
            On Dec 27, 2021 this sequence version replaced XM_006237529.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC168221.1, FQ229464.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN16676786, SAMN16676787
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-166               JAXUCZ010000004.1  169735015-169735180 c
            167-305             JAXUCZ010000004.1  169724806-169724944 c
            306-486             JAXUCZ010000004.1  169722636-169722816 c
            487-1034            JAXUCZ010000004.1  169705665-169706212 c
FEATURES             Location/Qualifiers
     source          1..1034
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="4"
                     /map="4q43"
     gene            1..1034
                     /gene="Hebp1"
                     /note="heme binding protein 1"
                     /db_xref="GeneID:362454"
                     /db_xref="RGD:1304581"
     exon            1..166
                     /gene="Hebp1"
                     /inference="alignment:Splign:2.1.0"
     CDS             89..661
                     /gene="Hebp1"
                     /note="isoform 1 is encoded by transcript variant 1"
                     /codon_start=1
                     /product="heme-binding protein 1 isoform 1"
                     /protein_id="NP_001385805.1"
                     /db_xref="GeneID:362454"
                     /db_xref="RGD:1304581"
                     /translation="MLGMIRNSLFGSVETWPWQVLSTGGKEDVSYEERACEGGKFATV
                     EVTDKPVDEALREAMPKIMKYVGGTNDKGVGMGMTVPISFAVFPNEDGSLQKKLKVWF
                     RIPNQFQGSPPTPSDQSVKIEEREGITVYSTQFGGYAKEADYVAHATQLRTTLEGTPA
                     TYQGDVYYCAGYDPPMKPYGRRNEVWLVKV"
     exon            167..305
                     /gene="Hebp1"
                     /inference="alignment:Splign:2.1.0"
     exon            306..486
                     /gene="Hebp1"
                     /inference="alignment:Splign:2.1.0"
     exon            487..1034
                     /gene="Hebp1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gtctactcac gcgctcactg ccgctcgccc tgtggacctt gctgccagtg agtggtacgc
       61 tcgatcgtcc agaccccacg gcgtcaccat gctgggcatg atcaggaact cactgttcgg
      121 gagcgtggag acgtggcctt ggcaggttct aagcaccggg ggcaaggaag acgtctccta
      181 tgaggaaaga gcctgcgaag ggggaaagtt tgctactgtg gaagtgacag acaaacctgt
      241 ggatgaggct ctccgggaag caatgcccaa gatcatgaag tacgtggggg gcaccaatga
      301 caaaggagtc ggcatgggaa tgacagtccc tatctctttt gccgtgtttc ccaacgaaga
      361 tggctccctg cagaagaagc tgaaagtctg gttccggatt ccgaaccaat ttcaaggcag
      421 cccgccaacg cccagtgacc agagcgtgaa aatcgaggag cgggagggca tcactgtcta
      481 ttctacgcaa ttcggtggtt atgccaagga agccgactat gttgctcacg ccacccagct
      541 acgtaccacc ctggagggca caccagccac ctaccagggt gatgtctact actgcgccgg
      601 gtatgaccct cccatgaagc cctatggacg tcgtaatgag gtctggcttg tgaaggtgtg
      661 agtcactggc tgaactgaga acatcgtgga agagtgccat gtgtcccctg acttggggtc
      721 aagaaggggc agtacttctt cagttccagc tttccttcaa aaatccctcg ctgccggttt
      781 tctgaaataa gtgaagactg gcagcattgt tctcaagtta ggatgttctg cgtcagatca
      841 ggaaaaaaaa aaatgccaag cagcatttcc tcagccatct gggtcactga aaactgatct
      901 ttttaaaatt atcaattttg tatttttgtt agtgaggaaa tatgtgattt atgcatgagc
      961 tttcgtctgt gattctttta agaactttgt ctagaaagaa cccaaaaata taaatctttg
     1021 acttatgcag taga
//
