LOCUS       XM_006256758            4075 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus histone deacetylase 6 (Hdac6),
            transcript variant X1, mRNA.
ACCESSION   XM_006256758
VERSION     XM_006256758.3
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051356.1) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Jan 9, 2024 this sequence was replaced by
            NM_001427029.1.
            
            On Jan 21, 2021 this sequence version replaced XM_006256758.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4075
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="X"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..4075
                     /gene="Hdac6"
                     /note="histone deacetylase 6; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 2
                     mRNAs, 41 ESTs, 4 long SRA reads, 8 Proteins, and 100%
                     coverage of the annotated genomic feature by RNAseq
                     alignments, including 217 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:108348065"
                     /db_xref="RGD:619981"
     CDS             277..3735
                     /gene="Hdac6"
                     /codon_start=1
                     /product="histone deacetylase 6"
                     /protein_id="XP_006256820.1"
                     /db_xref="GeneID:108348065"
                     /db_xref="RGD:619981"
                     /translation="MTSTGQDSSTRQRKSRHNPQSPLQDSSATLKRGGKKGAVPHSSP
                     NLAEVKKKGKMKKLSQPAEEDLIVGLQGLDLNSETRVPVGTGLVFDEQLNDFHCLWDD
                     SFPENPERLHAIKEQLILEGLLGRCVSFQARFAEKEELMLVHSLEYIDLMETTQYMNE
                     GELRVLAGTYDSVYLHPNSYSCACLATGSVLRLVDAVMGAEIRNGMAVIRPPGHHAQR
                     SLMDGYCMFNHLAVAARYAQKKHRIQRILIVDWDVHHGQGTQFIFDQDPSVLYFSIHR
                     YEHGRFWPHLKASNWSTTGFGQGQGYTINVPWNQVGMRDADYIAAFLHILLPVAFEFQ
                     PQLVLVAAGFDALHGDPKGEMSATPAGFAHLTHFLMGLAGGKLILSLEGGYNLHALAK
                     GVSGSLHTLLGDPCPMLESPVAPCASAQTSISCTLEALEPFWEVLERSVEPQDEDEVE
                     GDMLEDEEEEGHWEATALPMDTWPLLQNRTGLVYDERMMSHCNLWDNHHPETPQRILR
                     IMCHLEEVGLAARCLILPARPALDSELLTCHSAEYVERLRATEKMKTRDLHREGANFE
                     SIYICPSTFACAQLATGAACRLVEAVLSGEVLNGIAIVRPPGHHAEPDAACGFCFFNS
                     VAVAARHAQVIAGRALRILIVDWDVHHGNGTQHIFEEDPSVLYVSLHRYDRGTFFPMG
                     DEGASSQVGRAAGTGFTVNVPWNGPRMGDADYLATWHRLVLPIAYEFNPELVLISAGF
                     DAAQGDPLGGCQVTPEGYAHLTHLLMGLAGGRIILILEGGYNLTSISESMAACTHSLL
                     GDPPPQLTSLRPPQSGALASISEVIQVHRKYWRSLRLMKMEDKEERSSSRLVIKKLPQ
                     SASPVSAKGMTTPKGKVLEAGMRKPTAALPTKESTLGQAKAKTAKALLAQGQSSEQAA
                     KGTTLDLATSKDTVGGATTDQCASVAATENSANQTTSGEEASGETESFGTSPSSNASK
                     QTTGASPLHGAAAQQSPELGLSSTLELSSEAQEVQESEEGLLGEAAGGQDMNSLMLTQ
                     GFGDFNTQDVFYAVTPLSWCPHLMAVCPIPAAGLDVSQPCKTCGSVQENWVCLTCYQV
                     YCSRYVNAHMVCHHEASEHPLVLSCVDLSTWCYLCQAYVHHEDLQDVKNAAHQNKFGE
                     GMPHLQ"
ORIGIN      
        1 aaggattctg ctcgaaaggg gcagtcctct gagcagcggg gcaaagggga aagctggggg
       61 cgagatctgt gagagaggaa ggtgcgggct cggccctaca ggaggtggag ttgagtgagt
      121 ctttgagggt gctgccgagg ccgcggcagc ctggtctggc ggacgagaaa ggtgggtgat
      181 ttatctgggg agctaggctg aagcgggcag gttgcagaag ccaagcgttc cgagcgcaga
      241 ttagagagcc gttccaggag caaaggctct tcagccatga cctccaccgg ccaagattct
      301 tctaccaggc agcgaaagag taggcacaat ccccaatcgc cccttcagga ctccagcgcc
      361 accttgaagc gtggtgggaa gaagggtgct gtaccccact ccagccccaa tctagcggag
      421 gtaaagaaga aaggcaaaat gaagaagctc agccaaccag ctgaagaaga cctaatcgtt
      481 gggcttcaag ggctggatct gaactctgag acaagagtac cagttggtac tggattggta
      541 tttgatgaac agctaaatga cttccactgc ctttgggatg acagcttccc tgaaaaccct
      601 gagcggctcc atgccatcaa agagcagctg atcctggagg gcctcctggg ccgctgtgtg
      661 tcctttcagg cccggttcgc cgagaaggag gaactgatgt tggttcacag cctggaatac
      721 attgatctga tggagacaac ccagtacatg aatgaaggag aacttcgagt tcttgcaggc
      781 acctatgatt ccgtttatct gcatccgaac tcatattcat gtgcctgcct agctacaggc
      841 tctgtcctca ggctggtaga tgcagttatg ggggctgaga ttcggaatgg catggccgtc
      901 atcaggcctc ctggacacca tgctcagcgc agtcttatgg atgggtattg catgttcaac
      961 cacctggctg tggctgcccg ctatgcacaa aagaagcacc gcattcagag gattctcatc
     1021 gtggactggg atgtgcacca tggtcaagga acacagttca tcttcgacca ggaccccagt
     1081 gtactctatt tctccatcca ccgctatgag catggtcggt tctggcccca ccttaaggct
     1141 tctaactggt ccactacagg ctttggccaa ggccaaggat ataccatcaa tgtaccttgg
     1201 aaccaagtgg ggatgcggga tgccgactac attgctgctt tcctgcacat cctgctgcca
     1261 gttgcctttg agtttcagcc tcaactggtc ctggtggccg ctggatttga tgccctccat
     1321 ggagacccca agggagagat gtctgccact ccagcaggat ttgcccacct gacccatttc
     1381 cttatgggtt tggcaggagg caagttgatt ctgtctctgg agggtggcta taacctccat
     1441 gccttggcta agggcgtcag tggctcactc cacacccttc ttggagatcc ttgccccatg
     1501 ttggagtccc ctgttgcacc ttgtgcaagc gcccagactt ctatctcctg cactctagaa
     1561 gcccttgaac ccttctggga agtccttgag agatcagttg agccccagga tgaagatgaa
     1621 gtggaaggag acatgctaga ggatgaagag gaggaaggcc actgggaggc cactgctcta
     1681 ccaatggata catggccact gctccagaac cgcactgggc tggtctatga cgaaagaatg
     1741 atgagtcact gcaacctgtg ggacaatcat catcctgaga cacctcagcg catcctacgc
     1801 atcatgtgtc acctggagga ggtgggcctt gcagcacgct gtctcatcct acctgctcgg
     1861 cctgccctgg attctgaact ccttacgtgc cacagtgcgg agtatgtgga acgtcttcgg
     1921 gccacagaaa agatgaaaac tcgggatctg caccgtgaag gtgccaactt tgagtccatc
     1981 tacatctgcc ccagcacctt tgcctgcgca cagcttgcca caggcgctgc ctgccgcctg
     2041 gtggaagccg tgctttcagg agaggttttg aatggcattg caatagtgcg ccctccagga
     2101 caccatgcgg agccagatgc tgcttgtggt ttctgctttt tcaattctgt agctgtagct
     2161 gctcgccatg cccaagtcat tgctggacgt gccctgagga tcctaatcgt ggattgggat
     2221 gttcaccatg ggaatggaac tcagcacata tttgaggaag accccagtgt attatacgtg
     2281 tccctgcacc ggtatgaccg tggtactttc ttccccatgg gggatgaggg tgccagtagc
     2341 caagtagggc gagctgcagg tacaggcttc actgtcaatg tgccctggaa tgggccccgc
     2401 atgggggatg ctgattacct ggctacgtgg catcggctgg tacttcccat cgcctatgag
     2461 tttaacccag agctggtgct gatatcagct ggctttgatg ctgcccaagg ggacccactg
     2521 ggaggctgcc aagtgacacc tgagggttat gcccacctca cccacctgct gatgggcctt
     2581 gctggtggcc gtattattct tattctggag ggtggctaca acttgacatc catctctgaa
     2641 tctatggctg cctgcaccca ttccctcctt ggagacccac caccccagct tacttcgctc
     2701 cgacctcccc agtcaggagc cctggcttca atcagtgagg tcatccaagt gcatcgcaaa
     2761 tactggcgca gtttgcggtt aatgaagatg gaagacaagg aagaacgctc tagttctagg
     2821 cttgtcatca agaagctgcc ccagtcagct agtcctgtgt ccgctaaggg aatgaccaca
     2881 ccaaaaggaa aggttctcga agcaggcatg aggaagccca cagcggcatt acctacaaaa
     2941 gagtcgactc taggccaggc taaagcaaag acagctaagg cattgctcgc ccagggccag
     3001 tcctcagaac aagctgctaa gggaactaca ctggatctgg ccacctcaaa ggacactgtg
     3061 ggaggtgcca caactgacca gtgtgcttca gtagcagcta cagaaaactc agctaaccag
     3121 accacgtcag gggaggaggc ttcaggagaa actgagtcat tcggaacttc tccatcctca
     3181 aatgccagca agcagaccac aggagcttca cctctgcacg gagccgcagc ccagcagtcc
     3241 cccgagcttg ggctttccag cactttggag ctaagcagtg aagctcagga agtccaagaa
     3301 tccgaggagg gcctactagg agaagcagct ggaggtcagg acatgaacag cttgatgctg
     3361 acacaaggat ttggggactt taatacccag gatgtatttt atgccgtgac tccactatcc
     3421 tggtgtcccc acttgatggc ggtgtgcccc attcctgcag caggcctaga tgtgtcccaa
     3481 ccttgtaaga cctgtggatc ggttcaggag aactgggtgt gtctgacttg ttatcaggtg
     3541 tactgcagtc gctatgtcaa tgcccatatg gtctgccacc atgaagcctc tgaacaccct
     3601 ctggtcctca gctgtgttga cctgtctacc tggtgttacc tctgtcaggc ctatgtccac
     3661 cacgaggatc tccaagatgt gaagaacgct gcccaccaga acaagtttgg ggagggcatg
     3721 ccgcacttgc agtaaatccc agaccatgct gcctgtttac cttctgaggc cccacacaga
     3781 gcagcttagc tcactgcagt ctgtaccttg gatggggtgg cctcactttg acccgtcttg
     3841 aatatccttt gcaaggtgct tatttaagtg caaatccttt tcagaggact ctaatgtttg
     3901 gttttagatg tgcccctgcc cactgcctgc atgaccgttc tacccagatg ggaagaggga
     3961 caacttagta gccctaggaa ggagctgaga tcacaaggat gatgttgaag gagacaagtg
     4021 gcagtggtgg caggcctgca tatttaataa agttgaagtt gttacaaaac ctgaa
//
