LOCUS       NM_001106610            2529 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus histone deacetylase 11 (Hdac11), mRNA.
ACCESSION   NM_001106610 XM_001073226 XM_238362
VERSION     NM_001106610.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2529)
  AUTHORS   Peserico,A. and Simone,C.
  TITLE     Physical and functional HAT/HDAC interplay regulates protein
            acetylation balance
  JOURNAL   J Biomed Biotechnol 2011, 371832 (2011)
   PUBMED   21151613
  REMARK    Review article
REFERENCE   2  (bases 1 to 2529)
  AUTHORS   Liu,H., Hu,Q., D'ercole,A.J. and Ye,P.
  TITLE     Histone deacetylase 11 regulates oligodendrocyte-specific gene
            expression and cell development in OL-1 oligodendroglia cells
  JOURNAL   Glia 57 (1), 1-12 (2009)
   PUBMED   18627006
  REMARK    GeneRIF: Interaction of HDAC11 with acetylated histone H3 markedly
            increases oligodendrocyte-specific gene expression in developing
            cells.
REFERENCE   3  (bases 1 to 2529)
  AUTHORS   Gao,L., Cueto,M.A., Asselbergs,F. and Atadja,P.
  TITLE     Cloning and functional characterization of HDAC11, a novel member
            of the human histone deacetylase family
  JOURNAL   J Biol Chem 277 (28), 25748-25755 (2002)
   PUBMED   11948178
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC166430.1 and CN540732.1.
            
            On Oct 1, 2011 this sequence version replaced NM_001106610.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC166430.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132291, SAMD00132292
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-2500              BC166430.1         1-2500
            2501-2529           CN540732.1         1-29                c
FEATURES             Location/Qualifiers
     source          1..2529
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="Sprague-Dawley"
                     /db_xref="taxon:10116"
                     /chromosome="4"
                     /map="4q34"
     gene            1..2529
                     /gene="Hdac11"
                     /note="histone deacetylase 11"
                     /db_xref="GeneID:297453"
                     /db_xref="RGD:1311706"
     exon            1..72
                     /gene="Hdac11"
                     /inference="alignment:Splign:2.1.0"
     CDS             71..1114
                     /gene="Hdac11"
                     /EC_number="3.5.1.98"
                     /codon_start=1
                     /product="histone deacetylase 11"
                     /protein_id="NP_001100080.2"
                     /db_xref="GeneID:297453"
                     /db_xref="RGD:1311706"
                     /translation="MPHATQLYQHVPEKRWPIVYSPRYNITFMGLEKLHPFDAGKWGK
                     VINFLKEEKLLSDGMLVEAREASEEDLLVVHTRRYLNELKWSFVVATITEIPPVIFLP
                     NFLVQRKVLRPLRTQTGGTIMAGKLAVERGWAINVGGGFHHCSSDRGGGFCAYADITL
                     AIKFLFERVEGISRATIIDLDAHQGNGHERDFMGDKRVYIMDVYNRHIYPGDRFAKEA
                     IRRKVELEWGTEDEEYLEKVERNVRRSLQEHLPDVVVYNAGTDVLEGDRLGGLSISPA
                     GIVKRDEVVFRVVRAHDIPILMVTSGGYQKRTARIIADSILNLHDLGLIGPEFPYVPA
                     RNSSIPLLSRAVP"
     exon            73..221
                     /gene="Hdac11"
                     /inference="alignment:Splign:2.1.0"
     exon            222..322
                     /gene="Hdac11"
                     /inference="alignment:Splign:2.1.0"
     exon            323..439
                     /gene="Hdac11"
                     /inference="alignment:Splign:2.1.0"
     exon            440..482
                     /gene="Hdac11"
                     /inference="alignment:Splign:2.1.0"
     exon            483..559
                     /gene="Hdac11"
                     /inference="alignment:Splign:2.1.0"
     exon            560..622
                     /gene="Hdac11"
                     /inference="alignment:Splign:2.1.0"
     exon            623..719
                     /gene="Hdac11"
                     /inference="alignment:Splign:2.1.0"
     exon            720..898
                     /gene="Hdac11"
                     /inference="alignment:Splign:2.1.0"
     exon            899..2513
                     /gene="Hdac11"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ctccccgcta cacccctccc aaccctcccc gtgcggagtg gtgtccagag caggcagggc
       61 cggctgcggg atgcctcacg caacacagct gtaccagcat gtaccagaga aacgctggcc
      121 catcgtgtac tctccacgtt acaacatcac cttcatgggc ctagagaagc tgcacccctt
      181 tgatgctggg aaatggggca aggtgatcaa cttcctgaaa gaagagaagc tgctgtctga
      241 tggcatgctg gtggaggcga gggaggcctc ggaggaggac ctgctggtgg tgcacacaag
      301 gcgctatctc aacgagctga agtggtcctt tgtggtggct accatcactg agatcccccc
      361 tgtcatcttt ctccccaact tccttgtgca gaggaaggtg ttgaggcccc tgcggaccca
      421 gactggaggc accatcatgg cggggaagct ggctgtggaa cgaggctggg ccatcaatgt
      481 tggtggtggc ttccaccact gctccagtga ccgtggtggg ggcttctgtg cctatgcaga
      541 catcacactg gctatcaagt tcctgtttga acgtgtggaa ggcatttcca gagctaccat
      601 cattgatctg gatgcccacc agggcaatgg gcacgagcga gacttcatgg gcgacaagcg
      661 tgtatatatc atggatgttt acaaccgcca catctacccc ggggatcgct ttgctaaaga
      721 ggccatcagg cggaaggtgg agttggagtg gggcacagaa gatgaggagt atctggagaa
      781 ggtggagagg aatgtgagga ggtccctcca ggagcacctg cctgatgttg tggtgtacaa
      841 cgccggcaca gacgtcctgg agggagaccg ccttggcggg ctgtccatca gcccagcggg
      901 cattgtgaag agggatgaag tggttttccg ggtggtccga gcccatgata tacccatcct
      961 catggtgacc tcgggtgggt accagaagcg cacagcccgc attatcgccg actccatcct
     1021 caatttgcat gacctggggc tcattgggcc tgagtttccc tatgtcccgg cacggaactc
     1081 aagcatcccc ctgctttccc gtgctgtgcc ttgacggcta ctcacagaac attatcatac
     1141 ctgccccccc accccatcca cccgcccacc cgcctgtgtt tgttgctgtc aagacagctg
     1201 ccagtgagca tggaggggca ggaagagcag gagccagcct tgctggccat tcctccactc
     1261 cccaccaggt gcccaagggt ctctgggcct tggggtggaa gagctgagtc ccggggagga
     1321 gcccactggg atgcaagcag gtcatcagga gtcagggaag acagcttagc tgcagccaca
     1381 gggaggacct ctgggatggg gtgcctgctg tccagatcag ccagaagaag ggccctccct
     1441 gacccagttg gcttacttcc tcccttcagt ctggagaggg tcccctcctg gatgatggtg
     1501 cccataggtc tgaggaaagt ttccatagcc agcctccagg gggcactggg ttctcagcta
     1561 acaggtaata gtctctgata gagatttgga ggtctgaaga aggaagctag gattttccag
     1621 tttgggttcc ctcaatagat caagcccccc tatgttgatg gggtgggaca ttgagaatgc
     1681 ccaaggcccc caactttggc agtaatctcc tctgttcagc atggaaacaa gtttgggatg
     1741 agtgtttagc tcaggagtga ctctccaagc tggagtttat aatgggctgc tcaccaggat
     1801 ggagagaagg tgaggcctag cagacaggaa tgagatggag actggcagcc aagctagccc
     1861 taggtagggc ttgctggagg gagggcagcc aaggtaacat ttaggtacag tggccatgca
     1921 gaccttgggt gagctgcagt ctccagtggc ctcacccaaa gtgcccaatt ttcatctctg
     1981 gggccccaag gtctacctgc cctccggcca ttctaccctg aagggacagc cagggccctc
     2041 catgatgtag gcaggaaagc acccacccct agccagtgat tggcagcata accaaaggca
     2101 cagggggtaa gaggatgtgg gccagctggg cttcctcctg ccctggatct gccccaacta
     2161 caggactcat attcattacc atgtgggtat tcccacagcc ttcatggcgt ccttcatgct
     2221 ccctctgctg gagttgggag gatgccaaag tcaccagttg tctaaaccac tgacctagac
     2281 caaaccccac agtactaatg cagctccaca cccctctgcc atgacctctc tgcatctgac
     2341 tggaggttcc tcccaggaca ctggggagtg gtgacagcag tctgttactg tggagtttct
     2401 ctctgagtac catacaggct ccaggttgtt gctgtgtgtt ctgaggtaga cagacctgcc
     2461 tcctgaggac cactggaaat aaagattcaa aattcaccaa tccagacacc gaaaaaaaaa
     2521 aaaaaaaaa
//
