LOCUS       NM_001008357            2384 bp    mRNA    linear   ROD 04-DEC-2024
DEFINITION  Rattus norvegicus host cell factor C2 (Hcfc2), mRNA.
ACCESSION   NM_001008357 XM_235011
VERSION     NM_001008357.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2384)
  AUTHORS   Spedale,G., Timmers,H.T. and Pijnappel,W.W.
  TITLE     ATAC-king the complexity of SAGA during evolution
  JOURNAL   Genes Dev 26 (6), 527-541 (2012)
   PUBMED   22426530
  REMARK    Review article
REFERENCE   2  (bases 1 to 2384)
  AUTHORS   Rizki,G., Iwata,T.N., Li,J., Riedel,C.G., Picard,C.L., Jan,M.,
            Murphy,C.T. and Lee,S.S.
  TITLE     The evolutionarily conserved longevity determinants HCF-1 and
            SIR-2.1/SIRT1 collaborate to regulate DAF-16/FOXO
  JOURNAL   PLoS Genet 7 (9), e1002235 (2011)
   PUBMED   21909281
REFERENCE   3  (bases 1 to 2384)
  AUTHORS   Johnson,K.M., Mahajan,S.S. and Wilson,A.C.
  TITLE     Herpes simplex virus transactivator VP16 discriminates between
            HCF-1 and a novel family member, HCF-2
  JOURNAL   J Virol 73 (5), 3930-3940 (1999)
   PUBMED   10196288
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC085951.1.
            
            On Dec 16, 2004 this sequence version replaced XM_235011.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC085951.1, SRR8487231.21566.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760389 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2384
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="7"
                     /map="7q13"
     gene            1..2384
                     /gene="Hcfc2"
                     /note="host cell factor C2"
                     /db_xref="GeneID:314704"
                     /db_xref="RGD:1307385"
     exon            1..169
                     /gene="Hcfc2"
                     /inference="alignment:Splign:2.1.0"
     CDS             7..2178
                     /gene="Hcfc2"
                     /note="HCF-2; C2 factor"
                     /codon_start=1
                     /product="host cell factor 2"
                     /protein_id="NP_001008358.1"
                     /db_xref="GeneID:314704"
                     /db_xref="RGD:1307385"
                     /translation="MAAPSLLNWRRVSSFTGPVPRARHGHRAVAIRELMIIFGGGNEG
                     IADELHVYNTVTNQWFLPAVRGDIPPGCAAHGFVCDGTRILVFGGMVEYGRYSNELYE
                     LQASRWLWKKVKPQPPPSGLPPCPRLGHSFSLYGNKCYLFAGLANESEDSNNNVPRYL
                     NDFYELELQHGSGVVGWSVPATKGTVPSPRESHTAVIYCKRDSGSPKMYVFGGMCGAR
                     LDDLWQLDLETMSWSKPETKGTVPLPRSLHTASVIGNKMYIFGGWVPHKGENTENSPH
                     DCEWRCTSSFSYLNLDTAEWTTLVSDSQEDKKNSRPRPRAGHCAVAIGTRLYFWSGRD
                     GYKKALNSQVCCKDLWYLDTEKPPAPSQVQLIKATTNSFHVKWDEVPTVEGYLLQLNT
                     DLTHQAASPDASAAPNTLGGRTDPHRQGSNSILHNSVSDPANCTKPEHTAVAARGMSL
                     KSKPDSRAADSSVALHSPLAPNTSNNNSCMADMLWKSEVDEICALPATKISRVEAHAA
                     ATPFSKETPSNPVAILKAEQWCDVGIFKNNTALVSQFYLLPKGKQSMSKVGNADVPDY
                     SLLKKQDLVPGTVYKFRVAAINGCGIGPFSKLSEFKTCIPGFPGAPSTVRISKNVEGI
                     HLSWEPPTSPSGNILEYSAYLAIRTAQVQDNPSQLVFMRIYCGLKTSCIVTAGQLANA
                     HIDYTSRPAIVFRISAKNEKGYGPATQVRWLQGNSKKAPLS"
     exon            170..318
                     /gene="Hcfc2"
                     /inference="alignment:Splign:2.1.0"
     exon            319..479
                     /gene="Hcfc2"
                     /inference="alignment:Splign:2.1.0"
     exon            480..688
                     /gene="Hcfc2"
                     /inference="alignment:Splign:2.1.0"
     exon            689..773
                     /gene="Hcfc2"
                     /inference="alignment:Splign:2.1.0"
     exon            774..880
                     /gene="Hcfc2"
                     /inference="alignment:Splign:2.1.0"
     exon            881..1069
                     /gene="Hcfc2"
                     /inference="alignment:Splign:2.1.0"
     exon            1070..1237
                     /gene="Hcfc2"
                     /inference="alignment:Splign:2.1.0"
     exon            1238..1290
                     /gene="Hcfc2"
                     /inference="alignment:Splign:2.1.0"
     exon            1291..1471
                     /gene="Hcfc2"
                     /inference="alignment:Splign:2.1.0"
     exon            1472..1545
                     /gene="Hcfc2"
                     /inference="alignment:Splign:2.1.0"
     exon            1546..1677
                     /gene="Hcfc2"
                     /inference="alignment:Splign:2.1.0"
     exon            1678..1863
                     /gene="Hcfc2"
                     /inference="alignment:Splign:2.1.0"
     exon            1864..2360
                     /gene="Hcfc2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gggaagatgg cggctcccag cctcctcaac tggaggcggg tttcctcctt caccgggccg
       61 gtgccccgcg cccggcacgg acaccgagcg gtggccatcc gggagctgat gatcatcttc
      121 ggcgggggca acgagggcat cgcggacgag ctgcacgtct acaacaccgt taccaatcag
      181 tggttcctac cagctgtccg aggagacatc cccccaggct gcgcggccca cggttttgtc
      241 tgtgacggta ctagaatcct agtatttggg ggaatggttg aatatggaag atacagcaat
      301 gagttgtatg agttacaagc aagccgttgg ttatggaaaa aagtgaaacc ccagccccct
      361 ccttccggtt tacctccttg tcctcggctt ggacatagct tctctttata tggtaacaaa
      421 tgctatttgt ttgctggttt ggcaaatgaa agtgaagatt caaataataa tgtccccagg
      481 tatctcaatg atttctatga gttggagctg cagcatggct ctggtgttgt gggctggagc
      541 gttccagcca ccaaaggcac tgtgccttct ccacgggaat cccacactgc tgttatatac
      601 tgtaaaagag actctgggag tcctaagatg tatgtctttg gtgggatgtg cggtgctcgt
      661 ctggatgacc tatggcagct tgatttagaa actatgtcat ggtcaaaacc agaaactaaa
      721 gggacagtac cactcccacg aagccttcac acagccagtg ttataggaaa caagatgtac
      781 atttttggtg gatgggttcc acataaaggt gaaaacactg agaattctcc ccatgattgt
      841 gagtggaggt gcaccagctc gttttcgtac ctaaatctag atacagcaga gtggactact
      901 ctggtgtcag attcccagga agataaaaaa aactcaaggc caagaccgag agcaggacac
      961 tgtgccgttg cgatcggcac tcgactgtac ttctggagtg gaagagacgg ctacaaaaaa
     1021 gcccttaaca gtcaggtgtg ctgcaaggac ctgtggtatc ttgataccga gaaacctcca
     1081 gcaccatcac aagtccagtt aatcaaagct actaccaact ctttccatgt caagtgggat
     1141 gaagtgccta cggtcgaggg ctatcttctg cagttaaaca ctgacctgac gcaccaagcg
     1201 gcatcgcctg acgcttcagc agcaccaaat acgctaggag gcaggacgga ccctcacaga
     1261 caaggcagta atagcatcct tcataacagt gttagtgatc cagcaaactg tacaaaacct
     1321 gaacacacgg ctgtggctgc gagaggaatg tcactgaaga gcaaaccaga ctcaagagca
     1381 gcagactcca gtgttgcttt gcactcgcca ttggcgccta acacttccaa caacaacagc
     1441 tgtatggcgg acatgctgtg gaagagcgaa gttgacgaaa tatgtgctct gcctgcaact
     1501 aagatcagcc gtgtagaggc acatgctgca gcaacaccat tttctaaaga gacaccttca
     1561 aatccagtgg ccattttgaa agcagagcaa tggtgtgatg tggggatttt taaaaacaat
     1621 acagctttgg tgagccaatt ttatttgcta ccaaaaggaa aacaaagtat gtcaaaggta
     1681 ggaaatgcag acgtacccga ctacagtttg cttaagaaac aggaccttgt tccaggaaca
     1741 gtctataaat tcagggttgc tgcaatcaat ggttgtggaa taggcccttt cagtaaactc
     1801 agtgaattta aaacatgtat ccctggtttc cctggagctc cttctacagt ccgcatttct
     1861 aagaatgttg aaggtatcca cctttcctgg gagcctccaa cgtcaccctc tggaaatatt
     1921 ctggaatact cagcttactt ggctatccgc acagcacagg tgcaagacaa tcccagccaa
     1981 ctcgtgttca tgaggatcta ctgtggtctg aagacctcgt gcatagtgac tgctggacag
     2041 ctggcaaacg cgcacattga ttacacgtcc agacctgcca ttgtgttcag aatatcagca
     2101 aagaatgaaa agggctacgg acccgccacg caagtccgat ggcttcaagg taacagtaaa
     2161 aaagcccctt tgagttgagt tgtttttact aaagctgttg taatcgttat ttattagaaa
     2221 ctgttataaa catctgttct ttgagagtat tccctgactg tacttctagc agttatgaat
     2281 ttgagtttgt aagttgttct taaaatgtat ttgctcactt ctagatccaa ataaagatag
     2341 aaagaagcaa agactgaaaa aaaaaaaaaa aaaaaaaaaa aaaa
//
