LOCUS       NM_001100492             629 bp    mRNA    linear   ROD 07-FEB-2025
DEFINITION  Rattus norvegicus host cell factor C1 regulator 1 (Hcfc1r1),
            transcript variant 2, mRNA.
ACCESSION   NM_001100492 XM_001055621 XM_002724660 XM_002724661 XM_573052
VERSION     NM_001100492.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 629)
  AUTHORS   Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
            Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
            Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
            Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
            Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
            Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
            Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
            Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
            Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
            McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
            Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
            Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
            Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
            Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
            Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
            Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
            Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
            Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
  CONSRTM   Mammalian Gene Collection Program Team
  TITLE     Generation and initial analysis of more than 15,000 full-length
            human and mouse cDNA sequences
  JOURNAL   Proc Natl Acad Sci U S A 99 (26), 16899-16903 (2002)
   PUBMED   12477932
REFERENCE   2  (bases 1 to 629)
  AUTHORS   Bonaldo,M.F., Lennon,G. and Soares,M.B.
  TITLE     Normalization and subtraction: two approaches to facilitate gene
            discovery
  JOURNAL   Genome Res 6 (9), 791-806 (1996)
   PUBMED   8889548
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            FM050402.1, AY245001.1, BC168753.1 and BG373213.1.
            
            On or before May 30, 2010 this sequence version replaced
            XM_002724660.1, XM_001055621.2, XM_002724661.1, XM_573052.4.
            
            Transcript Variant: This variant (2) differs in the 5' UTR,
            compared to variant 1. Both variants 1 and 2 encode the same
            protein.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMD00132261,
                              SAMD00132262 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-62                FM050402.1         1-62
            63-412              AY245001.1         1-350
            413-609             BC168753.1         280-476
            610-629             BG373213.1         1-20                c
FEATURES             Location/Qualifiers
     source          1..629
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="10"
                     /map="10q12"
     gene            1..629
                     /gene="Hcfc1r1"
                     /gene_synonym="Hpip"
                     /note="host cell factor C1 regulator 1"
                     /db_xref="GeneID:287097"
                     /db_xref="RGD:727975"
     exon            1..134
                     /gene="Hcfc1r1"
                     /gene_synonym="Hpip"
                     /inference="alignment:Splign:2.1.0"
     CDS             49..399
                     /gene="Hcfc1r1"
                     /gene_synonym="Hpip"
                     /note="HCF-1 beta-propeller-interacting protein; inhibitor
                     of four 2; host cell factor C1 regulator 1
                     (XPO1-dependent)"
                     /codon_start=1
                     /product="host cell factor C1 regulator 1"
                     /protein_id="NP_001093962.1"
                     /db_xref="GeneID:287097"
                     /db_xref="RGD:727975"
                     /translation="MILQQPLERGPPGRDPRATTGVTLGLDTREPLHKHFLSEENMAT
                     HFSRLSLHNDHPYCSPPVTFPEALPPLRSPCPELLLWRYPGSLIPEALRLLRLGDNPS
                     PYYSASPAGEIMEL"
     exon            135..263
                     /gene="Hcfc1r1"
                     /gene_synonym="Hpip"
                     /inference="alignment:Splign:2.1.0"
     exon            264..613
                     /gene="Hcfc1r1"
                     /gene_synonym="Hpip"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ctctgctgct tgaatcccac ccctctatct gcaggacccc gagccgtaat gatcctgcaa
       61 cagcccctgg agcgaggccc cccagggcgg gacccacggg ccaccactgg ggtgactctt
      121 ggcctggata ccagggaacc cttgcacaag cacttcctgt ctgaggagaa catggccacc
      181 catttctccc gactcagcct acataatgac cacccctatt gcagtccccc tgtgactttt
      241 cccgaagccc tgccaccact caggagccct tgccccgagc tgcttctctg gcgctatccc
      301 gggagcctga ttcctgaggc cctccggctg ctgaggctgg gggataaccc cagtccctac
      361 tactctgcgt ccccagctgg ggagatcatg gagctctgag tgtcgatgac ctgtgtccct
      421 ccccaccttc ttcctgacta tagagaccag caactcccag aaagggatga aggccttctc
      481 caaacccggt gcctggccac caggaccttc ccctgacagg aggacactga gctcggtgga
      541 acgttagatt cgaagcagcc tgggaagaga aggtgtcacc ccattagtga ataaagacct
      601 gtgagcagtt gaaaaaaaaa aaaaaaaaa
//
