LOCUS       NM_001414734            8808 bp    mRNA    linear   ROD 18-FEB-2024
DEFINITION  Rattus norvegicus host cell factor C1 (Hcfc1), mRNA.
ACCESSION   NM_001414734 XM_006229597
VERSION     NM_001414734.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 8808)
  AUTHORS   Cui,W., Dai,X., Marcho,C., Han,Z., Zhang,K., Tremblay,K.D. and
            Mager,J.
  TITLE     Towards Functional Annotation of the Preimplantation Transcriptome:
            An RNAi Screen in Mammalian Embryos
  JOURNAL   Sci Rep 6, 37396 (2016)
   PUBMED   27869233
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8808)
  AUTHORS   Guo,Z., Neilson,L.J., Zhong,H., Murray,P.S., Zanivan,S. and
            Zaidel-Bar,R.
  TITLE     E-cadherin interactome complexity and robustness resolved by
            quantitative proteomics
  JOURNAL   Sci Signal 7 (354), rs7 (2014)
   PUBMED   25468996
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 8808)
  AUTHORS   Iwata,T.N., Cowley,T.J., Sloma,M., Ji,Y., Kim,H., Qi,L. and
            Lee,S.S.
  TITLE     The transcriptional co-regulator HCF-1 is required for INS-1
            beta-cell glucose-stimulated insulin secretion
  JOURNAL   PLoS One 8 (11), e78841 (2013)
   PUBMED   24250814
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 8808)
  AUTHORS   Zhou,P., Wang,Z., Yuan,X., Zhou,C., Liu,L., Wan,X., Zhang,F.,
            Ding,X., Wang,C., Xiong,S., Wang,Z., Yuan,J., Li,Q. and Zhang,Y.
  TITLE     Mixed lineage leukemia 5 (MLL5) protein regulates cell cycle
            progression and E2F1-responsive gene expression via association
            with host cell factor-1 (HCF-1)
  JOURNAL   J Biol Chem 288 (24), 17532-17543 (2013)
   PUBMED   23629655
REFERENCE   5  (bases 1 to 8808)
  AUTHORS   Shilatifard,A.
  TITLE     The COMPASS family of histone H3K4 methylases: mechanisms of
            regulation in development and disease pathogenesis
  JOURNAL   Annu Rev Biochem 81, 65-95 (2012)
   PUBMED   22663077
  REMARK    Review article
REFERENCE   6  (bases 1 to 8808)
  AUTHORS   Vogel,J.L. and Kristie,T.M.
  TITLE     The novel coactivator C1 (HCF) coordinates multiprotein enhancer
            formation and mediates transcription activation by GABP
  JOURNAL   EMBO J 19 (4), 683-690 (2000)
   PUBMED   10675337
REFERENCE   7  (bases 1 to 8808)
  AUTHORS   Lu,R. and Misra,V.
  TITLE     Potential role for luman, the cellular homologue of herpes simplex
            virus VP16 (alpha gene trans-inducing factor), in herpesvirus
            latency
  JOURNAL   J Virol 74 (2), 934-943 (2000)
   PUBMED   10623756
REFERENCE   8  (bases 1 to 8808)
  AUTHORS   Kristie,T.M., Vogel,J.L. and Sears,A.E.
  TITLE     Nuclear localization of the C1 factor (host cell factor) in sensory
            neurons correlates with reactivation of herpes simplex virus from
            latency
  JOURNAL   Proc Natl Acad Sci U S A 96 (4), 1229-1233 (1999)
   PUBMED   9990006
REFERENCE   9  (bases 1 to 8808)
  AUTHORS   Lai,J.S. and Herr,W.
  TITLE     Interdigitated residues within a small region of VP16 interact with
            Oct-1, HCF, and DNA
  JOURNAL   Mol Cell Biol 17 (7), 3937-3946 (1997)
   PUBMED   9199328
REFERENCE   10 (bases 1 to 8808)
  AUTHORS   Kristie,T.M., Pomerantz,J.L., Twomey,T.C., Parent,S.A. and
            Sharp,P.A.
  TITLE     The cellular C1 factor of the herpes simplex virus enhancer complex
            is a family of polypeptides
  JOURNAL   J Biol Chem 270 (9), 4387-4394 (1995)
   PUBMED   7876203
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JACYVU010000491.1.
            
            [WARNING] On Apr 3, 2024 this sequence was replaced by
            NM_001414734.2.
            
            On Dec 9, 2022 this sequence version replaced XM_006229597.3.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            RNAseq introns :: mixed sample support SAMD00132261, SAMD00132262
                              [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            inferred exon combination :: based on alignments, homology
            RefSeq Select criteria    :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1159              JACYVU010000491.1  777616-778774       c
            1160-1308           JACYVU010000491.1  771448-771596       c
            1309-1469           JACYVU010000491.1  770979-771139       c
            1470-1678           JACYVU010000491.1  770136-770344       c
            1679-1763           JACYVU010000491.1  769237-769321       c
            1764-1870           JACYVU010000491.1  768608-768714       c
            1871-2050           JACYVU010000491.1  767365-767544       c
            2051-2410           JACYVU010000491.1  766923-767282       c
            2411-2571           JACYVU010000491.1  766489-766649       c
            2572-2769           JACYVU010000491.1  764734-764931       c
            2770-2994           JACYVU010000491.1  764240-764464       c
            2995-3099           JACYVU010000491.1  763978-764082       c
            3100-3319           JACYVU010000491.1  763539-763758       c
            3320-3462           JACYVU010000491.1  763297-763439       c
            3463-3601           JACYVU010000491.1  763025-763163       c
            3602-3822           JACYVU010000491.1  762613-762833       c
            3823-5326           JACYVU010000491.1  760583-762086       c
            5327-5490           JACYVU010000491.1  760288-760451       c
            5491-5935           JACYVU010000491.1  759217-759661       c
            5936-6259           JACYVU010000491.1  758572-758895       c
            6260-6378           JACYVU010000491.1  758313-758431       c
            6379-6516           JACYVU010000491.1  758087-758224       c
            6517-6702           JACYVU010000491.1  757552-757737       c
            6703-7003           JACYVU010000491.1  756576-756876       c
            7004-7067           JACYVU010000491.1  755970-756033       c
            7068-8808           JACYVU010000491.1  754060-755800       c
FEATURES             Location/Qualifiers
     source          1..8808
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="X"
                     /map="Xq37"
     gene            1..8808
                     /gene="Hcfc1"
                     /gene_synonym="HCF; HCF-1; RGD1563804"
                     /note="host cell factor C1"
                     /db_xref="GeneID:363519"
                     /db_xref="RGD:1563804"
     exon            1..1159
                     /gene="Hcfc1"
                     /gene_synonym="HCF; HCF-1; RGD1563804"
                     /inference="alignment:Splign:2.1.0"
     CDS             967..7107
                     /gene="Hcfc1"
                     /gene_synonym="HCF; HCF-1; RGD1563804"
                     /note="host cell factor 1-like; C1 factor"
                     /codon_start=1
                     /product="host cell factor 1"
                     /protein_id="NP_001401663.1"
                     /db_xref="GeneID:363519"
                     /db_xref="RGD:1563804"
                     /translation="MASAVSPANLPAVLLQPRWKRVVGWSGPVPRPRHGHRAVAIKEL
                     IVVFGGGNEGIVDELHVYNTATNQWFIPAVRGDIPPGCAAYGFVCDGTRLLVFGGMVE
                     YGKYSNDLYELQASRWEWKRLKAKTPKNGPPPCPRLGHSFSLVGNKCYLFGGLANDSE
                     DPKNNIPRYLNDLYILELRPGSGVVAWDIPITYGVLPPPRESHTAVVYTEKDNKKSKL
                     VIYGGMSGCRLGDLWTLDIETLTWNKPSLSGVAPLPRSLHSATTIGNKMYVFGGWVPL
                     VMDDVKVATHEKEWKCTNTLACLNLDTMAWETILMDTLEDNIPRARAGHCAVAINTRL
                     YIWSGRDGYRKAWNNQVCCKDLWYLETEKPPPPARVQLVRANTNSLEVSWGAVATADS
                     YLLQLQKYDIPATAATATSPTPNPVPSVPANPPKSPAPAAAAPAVQPLTQVGITLVPQ
                     AAAAPPSTTTIQVLPTVPGSSISVPTAARTQGVPAVLKVTGPQATTGTPLVTMRPASQ
                     AGKAPVTVTSLPASVRMVVPTQSAQGTVIGSNPQMSGMAALAAAAAATQKIPPSSAPT
                     VLSVPAGTTIVKTVAVTPGTTTLPATVKVASSPVMVSNPATRMLKTAAAQVGTSVSSA
                     ANTSTRPIITVHKSGTVTVAQQAQVVTTVVGGVTKTITLVKSPISVPGGSALISNLGK
                     VMSVVQTKPVQTSAVTGQASTGPVTQIIQTKGPLPAGTILKLVTSADGKPTTIITTTQ
                     ASGAGTKPTILGISSVSPSTTKPGTTTIIKTIPMSAIITQAGATGVTSSPGIKSPITI
                     ITTKVMTSGTGAPAKIITAVPKIATGHGQQGVTQVVLKGAPGQPGTILRTVPMGGVRL
                     VTPVTVSAVKPAVTTLVVKGTTGVTTLGTVTGTVSTSLAGAGAHSTSASLATPITTLG
                     TIATLSSQVINPTAITVSAAQTTLTAAGGLTTPTITMQPVSQPTQVTLITAPSGVEAQ
                     PVHDLPVSILASPTTEQPTATVTIADSGQGDVQPGTVTLVCSNPPCETHETGTTNTAT
                     TTVVANLGGHPQPTQVQFVCDRQEAAASLVTSAVGQQNGNVVRVCSNPPCETHETGTT
                     NTATTATSNMAGQHGCSNPPCETHETGTTSTATTAMSSMGTGQQRDARRATNTPTVVR
                     ITVAPGALERAQGTVKPPCQTQQTNMTSTTMTVQATGAPCSAGPLLRPSVALETGSHS
                     PAFVQLALPSVRVGLSGPSSKDVPTGRQPETYHTYTTNTPTTARSIMVAGELGTARVV
                     PTSQYDCLQASSPSSTMTMTALEALLCPSATVTQVCSNPPCETHETGTTNTATTSNAG
                     SAQRVCSNPPCETHETGTTHTATTATSNGGAGQPEGGQQPASGHPCETHQTTSTGTTM
                     SVSVGALIPDATPSHGTLESGLEVVAVPTVTSQAGATLLASFSTQRVCSNPPCETHET
                     GTTHTATTVTSNMSSNQDPPPAASDQGEVASTQGDSTNITSASAITTTVSSTLPRAVT
                     TVTQSTPVPGPSVPPPEELQVSPGPRQQLPPRQLLQSASTPLMGESAEVLSASQTPEL
                     QAAVDLSSTGDPSSVQEPTTSAVVATVVVQPPQPTQSEVDQLSLPQELMAEAQAGTTT
                     LMVTGLTPEELAVTAAAEAAAQAAATEEAQALAIQAVLQAAQQAVMGTGEPMDTSEAA
                     AAVTQAELGHLSAEGQEGQATTIPIVLTQQELAALVQQQQQLQEAQAQAQQQHHLPTE
                     ALAPADSLNDPSIESNCLNELASAVPSTVALLPSTATESLAPSNTFVAPQPVVVASPA
                     KMQAAATLTEVANGIESLGVKPDLPPPPSKAPIKKENQWFDVGVIKGTSVMVTHYFLP
                     PDDAVQSDDDSGTVPDYNQLKKQELQPGTAYKFRVAGINACGRGPFSEISAFKTCLPG
                     FPGAPCAIKISKSPDGAHLTWEPPSVTSGKIIEYSVYLAIQSSQASGEPKSSTPAQLA
                     FMRVYCGPSPSCLVQSSSLSNAHIDYTTKPAIIFRIAARNEKGYGPATQVRWLQETSK
                     DSSGTKPASKRPMSSPEMKSAPKKSKADGQ"
     exon            1160..1308
                     /gene="Hcfc1"
                     /gene_synonym="HCF; HCF-1; RGD1563804"
                     /inference="alignment:Splign:2.1.0"
     exon            1309..1469
                     /gene="Hcfc1"
                     /gene_synonym="HCF; HCF-1; RGD1563804"
                     /inference="alignment:Splign:2.1.0"
     exon            1470..1678
                     /gene="Hcfc1"
                     /gene_synonym="HCF; HCF-1; RGD1563804"
                     /inference="alignment:Splign:2.1.0"
     exon            1679..1763
                     /gene="Hcfc1"
                     /gene_synonym="HCF; HCF-1; RGD1563804"
                     /inference="alignment:Splign:2.1.0"
     exon            1764..1870
                     /gene="Hcfc1"
                     /gene_synonym="HCF; HCF-1; RGD1563804"
                     /inference="alignment:Splign:2.1.0"
     exon            1871..2050
                     /gene="Hcfc1"
                     /gene_synonym="HCF; HCF-1; RGD1563804"
                     /inference="alignment:Splign:2.1.0"
     exon            2051..2410
                     /gene="Hcfc1"
                     /gene_synonym="HCF; HCF-1; RGD1563804"
                     /inference="alignment:Splign:2.1.0"
     exon            2411..2571
                     /gene="Hcfc1"
                     /gene_synonym="HCF; HCF-1; RGD1563804"
                     /inference="alignment:Splign:2.1.0"
     exon            2572..2769
                     /gene="Hcfc1"
                     /gene_synonym="HCF; HCF-1; RGD1563804"
                     /inference="alignment:Splign:2.1.0"
     exon            2770..2994
                     /gene="Hcfc1"
                     /gene_synonym="HCF; HCF-1; RGD1563804"
                     /inference="alignment:Splign:2.1.0"
     exon            2995..3099
                     /gene="Hcfc1"
                     /gene_synonym="HCF; HCF-1; RGD1563804"
                     /inference="alignment:Splign:2.1.0"
     exon            3100..3319
                     /gene="Hcfc1"
                     /gene_synonym="HCF; HCF-1; RGD1563804"
                     /inference="alignment:Splign:2.1.0"
     exon            3320..3462
                     /gene="Hcfc1"
                     /gene_synonym="HCF; HCF-1; RGD1563804"
                     /inference="alignment:Splign:2.1.0"
     exon            3463..3601
                     /gene="Hcfc1"
                     /gene_synonym="HCF; HCF-1; RGD1563804"
                     /inference="alignment:Splign:2.1.0"
     exon            3602..3822
                     /gene="Hcfc1"
                     /gene_synonym="HCF; HCF-1; RGD1563804"
                     /inference="alignment:Splign:2.1.0"
     exon            3823..5326
                     /gene="Hcfc1"
                     /gene_synonym="HCF; HCF-1; RGD1563804"
                     /inference="alignment:Splign:2.1.0"
     exon            5327..5490
                     /gene="Hcfc1"
                     /gene_synonym="HCF; HCF-1; RGD1563804"
                     /inference="alignment:Splign:2.1.0"
     exon            5491..5935
                     /gene="Hcfc1"
                     /gene_synonym="HCF; HCF-1; RGD1563804"
                     /inference="alignment:Splign:2.1.0"
     exon            5936..6259
                     /gene="Hcfc1"
                     /gene_synonym="HCF; HCF-1; RGD1563804"
                     /inference="alignment:Splign:2.1.0"
     exon            6260..6378
                     /gene="Hcfc1"
                     /gene_synonym="HCF; HCF-1; RGD1563804"
                     /inference="alignment:Splign:2.1.0"
     exon            6379..6516
                     /gene="Hcfc1"
                     /gene_synonym="HCF; HCF-1; RGD1563804"
                     /inference="alignment:Splign:2.1.0"
     exon            6517..6702
                     /gene="Hcfc1"
                     /gene_synonym="HCF; HCF-1; RGD1563804"
                     /inference="alignment:Splign:2.1.0"
     exon            6703..7003
                     /gene="Hcfc1"
                     /gene_synonym="HCF; HCF-1; RGD1563804"
                     /inference="alignment:Splign:2.1.0"
     exon            7004..7067
                     /gene="Hcfc1"
                     /gene_synonym="HCF; HCF-1; RGD1563804"
                     /inference="alignment:Splign:2.1.0"
     exon            7068..8808
                     /gene="Hcfc1"
                     /gene_synonym="HCF; HCF-1; RGD1563804"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 acacaagatg gcggctccca gggaggaggc atgatcgccc tgccgttacc gcttctcctg
       61 ccgtacaatt gtcacttcgg gtcttaactc ctgctctttc gagcggctcc tgtgggaagg
      121 agtcttaagg agggaagcga ggattggacg ctgccttttg tttggtttgc tgtggaagaa
      181 ctgtccagga agaagagaat aggggggggg ggagaagcta gtctcaagat ggcggctccc
      241 agggcggccg gcgcagcctg aattcagagg cggactcaag ggagaggtgc taaaccttac
      301 gagccatacg gctcgggacc ccgaacaaca cccgggagtt cgagtccgtt tcgccagctt
      361 ctgacacgcc tttattattt aggaacgttg gggttctgcg gtcggtgtct taagtgctgg
      421 gtggggaagc aggacggtct caagatggcg gcttccacaa ttgtggtctg actgccgacg
      481 gagctgagac aaccgcggca tttgtggctc ttttccaccc gccccggaag ccagccagtg
      541 ctggggacgg ggggtgtggg aaccgggccg gggctccgcc atttccggcg ggggagggct
      601 acgactgagg aagggaggag agagaggcgg ctcaagatgg cggctcccag agcctcctgc
      661 tcgagcttct aagcgggaac acccaggcaa atagttagag cgacggcgct cggtggcctc
      721 cagcttctcg gaaataggtg ctctgcagtt ttgagaagct tttaaggata cgagccgagt
      781 gagaaggggg gggaaagagc caaaggaagg aggatagtta agatggcggc ctccatggag
      841 tcgtccaccg ctgtgtaagg agccgcttct tcgtgagagc tgccttagac gaaagggggt
      901 gtgtgaagaa ttaagggtat ccctcccgtt cagtgacttc ttcccactgc atccttaacc
      961 ggaactatgg cttcggctgt gtcccccgct aacttgccag cggtgcttct acagccccgc
     1021 tggaaacggg tggtgggttg gtcgggtccc gtgccgcgac cccgccacgg ccaccgtgca
     1081 gtagctatca aggagcttat agtggtgttt ggcggcggca atgaggggat agtggacgaa
     1141 ctacacgtgt acaacactgc gaccaaccag tggttcatcc cagctgtgag aggggatatc
     1201 cctccagggt gtgcagccta tggctttgta tgtgatggta ctcgcctgct ggtgtttggt
     1261 ggaatggtag agtatggaaa atacagcaac gacctctatg agctccaggc aagtcgctgg
     1321 gaatggaaga gactgaaggc aaagacaccc aaaaacgggc ctcctccgtg tcctcggctt
     1381 ggacacagtt tctcccttgt gggcaacaaa tgttacctgt ttgggggtct ggccaatgat
     1441 agtgaggacc ccaagaacaa cattccgagg tacctgaatg acttatatat tctcgaacta
     1501 cggccaggct ctggagtggt agcttgggac attcccatca cttatggtgt ccttcctcca
     1561 ccccgggagt cacatactgc tgtggtctac actgaaaaag ataacaagaa atccaagctg
     1621 gtgatctatg gagggatgag tggctgcagg ctaggggacc tttggaccct ggacattgag
     1681 acactgacat ggaataagcc cagccttagt ggggtggcac cccttcctcg cagcctccac
     1741 tctgcaacca ccataggaaa caaaatgtat gtatttggtg gctgggtgcc ccttgtcatg
     1801 gacgatgtca aagtggccac acacgagaag gaatggaagt gtaccaacac actggcttgt
     1861 ctcaacctgg ataccatggc ctgggaaacc atcctgatgg atacactgga ggacaacatt
     1921 cctcgagctc gagcaggcca ctgtgctgtt gccatcaata ctcgcctgta tatttggagt
     1981 ggccgtgatg gctatcgcaa ggcctggaac aatcaggtct gctgcaagga cctgtggtat
     2041 ctggagacag aaaagccacc acccccagcc cgagttcaac tagtacgagc caacaccaac
     2101 tcactggagg ttagctgggg tgcagtggca acagccgaca gttaccttct acaactccag
     2161 aaatatgaca ttcctgccac agctgctacg gctacctccc ccactcccaa tccagtcccg
     2221 tctgtgcctg ccaaccctcc caagagccct gcgccagcag cagctgcacc tgctgtacaa
     2281 ccactgaccc aagtaggcat cacacttgtg ccccaggctg ccgctgcacc cccaagcaca
     2341 accaccatcc aggtcttgcc gacagtgcca ggcagctcta tttctgtgcc cactgcagcc
     2401 aggactcaag gtgtccctgc tgttctcaaa gtgactggtc ctcaagctac aacaggaaca
     2461 ccactggtca ccatgagacc tgcaagccag gctggaaaag ctcctgtcac tgtgacttcc
     2521 ctgcctgcca gtgtgagaat ggttgtaccc actcagagtg cccagggcac ggtgattggc
     2581 agcaacccac agatgagtgg gatggctgca ttggctgctg ctgctgctgc cacacagaaa
     2641 atccctcctt cctcagcacc cacagtgcta agtgtcccag caggcaccac cattgtcaag
     2701 acagtggctg tgacacctgg tacaaccact cttccagcca ctgtgaaggt ggcctcctca
     2761 cctgttatgg tgagcaaccc agctactcga atgctaaaga ctgcagctgc ccaagtgggg
     2821 acatctgtgt cctctgctgc caacacatct acccgcccta tcatcacagt acataaatca
     2881 gggactgtaa cagtggccca gcaagcccag gtggtgacca cggtggtagg cggagtcacc
     2941 aagaccatca ctctagtgaa gagccccatc tctgtcccgg gaggcagtgc tctgatttcc
     3001 aatcttggaa aagtgatgtc agtggtccag accaaaccag ttcagacttc agcagtgaca
     3061 ggccaagcat ctacaggtcc tgtgactcag atcatccaga ccaaaggacc cctgccagca
     3121 gggactatcc tgaagttggt gacatcagca gatggcaagc ccacaaccat catcaccacc
     3181 acacaggcta gtggggcagg gaccaagccc actatcctgg gcatcagtag tgtctctcct
     3241 agcaccacca aacccggcac aactaccatc attaagacca ttcccatgtc agcaattatc
     3301 acccaggcag gcgccacagg tgttaccagc agtcctggca ttaagtcccc catcacaatt
     3361 atcaccacca aggtgatgac ttcaggaaca ggagcacctg ccaaaatcat cactgctgtc
     3421 cccaagattg ctactggcca tgggcaacaa ggagtgaccc aggtggtgct aaagggggcc
     3481 cctggacagc caggcaccat cctccgcact gtgcccatgg gcggcgttcg cctggtcacc
     3541 cctgtcaccg tctccgctgt caagccagct gtcaccacat tggttgtgaa gggcaccaca
     3601 ggtgttacaa cactaggcac agtgacaggc actgtctcca ccagccttgc cggagctggg
     3661 gcacatagca ccagtgcttc tctggctaca cctatcacta ctttgggcac cattgctact
     3721 ctctcaagtc aggtgatcaa ccctactgct atcacagtgt cagctgcaca gactacacta
     3781 acagctgctg gtggactcac cacacctaca atcacaatgc agcctgtctc ccagcctacc
     3841 caggtgactc tgatcacagc acctagcggg gttgaggccc aacctgtaca tgaccttcct
     3901 gtgtccattt tggcctcacc tactacagag caacccacag caacagtcac tatcgctgac
     3961 tcaggccagg gtgatgtaca acctggcact gtgacactgg tgtgttccaa cccaccctgt
     4021 gaaacccatg aaacaggcac caccaacaca gctaccacca ctgttgtggc taaccttggg
     4081 ggacatcctc agcctaccca ggtgcagttt gtttgtgaca gacaggaggc agctgcttca
     4141 cttgtgacct cagctgtggg acaacagaat ggtaatgtgg tccgtgtctg ttcaaacccc
     4201 ccctgtgaaa cccatgagac aggcaccacc aacactgcca caacagccac ctcaaacatg
     4261 gctgggcagc atggctgctc gaatcctccc tgcgagactc atgagacagg taccaccagc
     4321 actgccacta cagcaatgtc cagcatgggc actgggcagc agcgagacgc tcgtcgtgcc
     4381 actaacaccc ccactgtagt gcggatcact gtggctcctg gggcattgga aagagcccag
     4441 ggtactgtga agcctccgtg ccaaacccag cagaccaaca tgaccagcac caccatgact
     4501 gtgcaggcca ctggagctcc atgctcagct ggcccactgc tcaggccaag tgtggcactg
     4561 gagactggga gccatagccc tgccttcgtg caactagccc ttccaagtgt cagagttggg
     4621 ctaagtggcc ccagcagcaa ggacgtgccc acagggcgcc aaccagagac atatcatact
     4681 tacacaacca ataccccaac cacagcccgt tctatcatgg ttgctgggga gcttggtaca
     4741 gctcgggtgg tccccacatc tcaatatgat tgcctccagg caagctctcc cagtagcacc
     4801 atgactatga cagccctaga ggccctgctg tgcccttcag ctactgtgac ccaagtctgc
     4861 tccaacccac catgtgagac ccatgagacg ggtaccacca acaccgccac tacctccaat
     4921 gcgggcagtg ctcagcgagt atgctctaac ccaccttgtg agactcatga gacgggcacc
     4981 acacacacag ctaccactgc cacatcaaat ggaggcgcag gccagcctga gggtggacaa
     5041 cagcctgcca gtggccatcc ctgcgagaca caccagacca cttccactgg caccactatg
     5101 tcagtcagtg tgggtgccct gattcctgat gccactccct ctcatgggac cctggagtct
     5161 ggtttagagg tggtagcagt gcccactgtc acctcccagg ctggtgccac attgctggcc
     5221 tctttctcaa cacagagggt atgctccaat cctccttgcg agacccacga gacaggtaca
     5281 acgcacacag ccaccactgt cacctctaac atgagctcaa accaagaccc tccaccagct
     5341 gccagtgacc aaggagaagt ggcgagtacc caaggtgaca gcacaaatat caccagtgcc
     5401 agtgctatca ctacaactgt gtcttctaca ctgccaagag cagtgaccac tgtgacacag
     5461 tctacaccag tcccaggtcc ttctgtgccg cccccagagg aactccaggt ctcaccaggg
     5521 cctcgccagc agctgcctcc aaggcaactc ctgcagtctg cctccacacc cctgatgggg
     5581 gagtccgccg aggtcctgtc agcctcccag acccctgagc tccaggccgc cgtggatctg
     5641 agcagcactg gggacccatc ttcagtccag gagcctacca cctctgctgt tgtggccact
     5701 gtggtggtcc aaccacccca acccacacag tctgaagtag accagttatc acttccccaa
     5761 gagctgatgg ctgaagccca ggcgggcacc acaaccctta tggtaacagg gctcactcca
     5821 gaggagctgg cagtgactgc tgctgctgaa gcagctgctc aagctgcagc cactgaagaa
     5881 gctcaagcct tggccatcca ggctgtgctc caggctgcac agcaggctgt catgggcact
     5941 ggggagccca tggatacatc tgaagcagca gcagcagtga cacaagcaga actgggtcat
     6001 ctttcagctg aaggccaaga gggtcaggct accaccatac ccattgtgct gacacagcag
     6061 gagcttgcag ctcttgtaca gcagcagcag cagctccagg aggctcaagc ccaagcccag
     6121 caacagcacc accttcccac tgaggctctg gccccagctg acagtctcaa tgacccatcc
     6181 atcgagagca actgcctcaa tgagttagct agtgctgtcc ccagcactgt ggccttgcta
     6241 ccctcaacag ctactgagag tttggctcca tctaacacat ttgtggctcc tcagcctgtt
     6301 gttgtagcca gtccagcaaa gatgcaggct gcagcaaccc ttactgaagt ggcaaatggc
     6361 attgagtccc tgggtgtgaa accggacttg ccacccccac ccagcaaagc ccctataaaa
     6421 aaggagaacc agtggtttga tgtgggggtc attaaaggta ccagtgtaat ggtgacacac
     6481 tattttctgc caccagatga tgctgttcag tcagatgatg actcaggcac cgttccagac
     6541 tataaccagc taaagaagca ggagctgcag ccaggcacag cttataaatt tcgagttgct
     6601 ggaatcaatg cttgtggccg gggccccttc agtgagatct cagcctttaa gacttgtctg
     6661 cctggttttc caggggctcc ttgtgctatt aaaatcagca agagcccaga tggtgctcac
     6721 ctcacctggg agccaccctc tgtgacctcc ggcaagatta tcgagtactc tgtgtacctg
     6781 gccatccaga gctcacaggc cagtggtgag cccaagagct ctaccccagc ccagctggcc
     6841 ttcatgcgag tatactgtgg gcctagccct tcctgccttg tgcagtcctc cagcctctcc
     6901 aacgcccaca ttgactatac tacaaagcct gccatcatct tccgcattgc tgcccgcaat
     6961 gaaaagggct acggccctgc cacacaagtg aggtggttac aagaaaccag taaagacagc
     7021 tctggcacca agccagctag caagcggccc atgtcgtctc cagaaatgaa atctgctcca
     7081 aagaagtcta aggctgatgg tcagtgagga agctggccag catctggatc ctccagaccc
     7141 ctctgcttca ggaatgccct atagggccca ccttcccgcc ctgcccacct ggcctttgca
     7201 cttcaccctc accagctact ggccaccatt cagtctcccc ctttccctct gtttttacaa
     7261 taaagaaagc acattttacc attgctgttg ggaggaagca gaaggcagat tggaaagaac
     7321 ggcgagtaag tgcaagttgt gctccttcct tttccctacc tgatgccctc cctgggttga
     7381 gtatgactgg acagttcaga gactttggga aaagaaatta aaactgaaaa caaaagagat
     7441 agttcccata cttaagcctg cactcgtttg tagttcattt cccttggcct gagagacagc
     7501 caagggctgg agggggaagg gcatccccca agttctctca gaggcttttc ccagcaggta
     7561 cccatcctgg gtatctgtct ggctctgttt tgttttgtta ctatccttgt atttccagcc
     7621 acctcccatc ccttcttcaa gcttagccag acctatctcg cccagcaaag tcacaggaag
     7681 cttaagtatc tcagaggcct ttgagtttcc cactcaacac ctctctctcc tttcaaaaga
     7741 gggagggggg gagccttggt tggtctgagc agtggctgtg aaatcctccc aatgggcaca
     7801 gaatggcccc cagtaaccct ggctttggcc tacctttttg agcctggggg ccacatcacc
     7861 aactgctgca tttgttgtat tttttaagtt gaaattaatg aagttaacat ttttattgta
     7921 attttagcct tagcgtgtgg gggtttatcc ctttttgtta gctgtgtaca gaatgtgtat
     7981 cctatctcct cccccaccct ccatcctatc ccacccctca tccccttacc cccccccccc
     8041 agctaatcat tggcaggggt cttcctgggg aaaggctaaa agagcagcta gagtaggaga
     8101 gaaacagagt gtcttgggtg ggacttggta gacactgccc caatatccta ttgctagccc
     8161 ctgcctgctt ctggaacagt gtgagaccat taaacttcat tccttgtggg ttagcactta
     8221 acatgtagag gcttgggctt aaaggtggtg tccaccttaa tcagcatcac tttcagagac
     8281 tgaccctaaa caacacagca ggaacaggga acaggtggga ctttgacccc cttggaggca
     8341 gcccaggatg gcagtggggt atgccatatc tatccacaga ggctatgggt aggtaccaaa
     8401 taccaactca gtaattaatt ttgtagcatt gtccccaagc tctggatttt ttttttctct
     8461 ccaggaccca agttttaggc aatgagtaat gcttgcaagc aagttactga aggatttaaa
     8521 aatggacagc caatgtgttc agcagctctg gcttgtaccc cctgggcctc tagtgtattg
     8581 tattatattt ctctgtggaa agtcatgttt agtcaaattc gaacccactc gcctgttccc
     8641 tttgttttcc ctatcccttc tcctgagcac cctttgattt ctgaggacag tactacccat
     8701 tcatctattg tagagtaacc cttgtgactc aatattacca tagtgcgatg ttgttttgtg
     8761 ctattttgaa caattaaaaa agactttttt tgaaataacc atctggta
//
