LOCUS       NM_001172845             589 bp    mRNA    linear   ROD 27-MAR-2024
DEFINITION  Rattus norvegicus hemoglobin subunit zeta (Hbz), mRNA.
ACCESSION   NM_001172845 XM_002724665 XM_002727757
VERSION     NM_001172845.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 589)
  AUTHORS   Bithell,A., Alberta,J., Hornby,F., Stiles,C.D. and Williams,B.P.
  TITLE     Expression of the guanine nucleotide exchange factor, mr-gef, is
            regulated during the differentiation of specific subsets of
            telencephalic neurons
  JOURNAL   Brain Res Dev Brain Res 146 (1-2), 107-118 (2003)
   PUBMED   14643017
REFERENCE   2  (bases 1 to 589)
  AUTHORS   Weiss,M.J., Keller,G. and Orkin,S.H.
  TITLE     Novel insights into erythroid development revealed through in vitro
            differentiation of GATA-1 embryonic stem cells
  JOURNAL   Genes Dev 8 (10), 1184-1197 (1994)
   PUBMED   7926723
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000010.1.
            
            On or before May 13, 2010 this sequence version replaced
            XM_002724665.1, XM_002727757.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: CD373355.1, CD372785.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN06680426, SAMN06680436
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-145               JAXUCZ010000010.1  15849613-15849757   c
            146-350             JAXUCZ010000010.1  15848623-15848827   c
            351-589             JAXUCZ010000010.1  15848279-15848517   c
FEATURES             Location/Qualifiers
     source          1..589
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="10"
                     /map="10q12"
     gene            1..589
                     /gene="Hbz"
                     /gene_synonym="Glne1; RGD1307486"
                     /note="hemoglobin subunit zeta"
                     /db_xref="GeneID:287168"
                     /db_xref="RGD:1307486"
     exon            1..145
                     /gene="Hbz"
                     /gene_synonym="Glne1; RGD1307486"
                     /inference="alignment:Splign:2.1.0"
     CDS             51..479
                     /gene="Hbz"
                     /gene_synonym="Glne1; RGD1307486"
                     /note="zeta-globin; hemoglobin, zeta; globin e1"
                     /codon_start=1
                     /product="hemoglobin subunit zeta"
                     /protein_id="NP_001166316.1"
                     /db_xref="GeneID:287168"
                     /db_xref="RGD:1307486"
                     /translation="MSLMKNERAIIMSMWDKMAPHAEPIGTETLERLFSSYPQTKTYF
                     PHFDLHHGSQQLRAHGSKILAAVGDAVKNIDNLSGALTKLSELHAYILRVDPVNFKLL
                     SHCLLVTLAAHFPADFTPEVHEAWDKFMSILSSVLTEKYR"
     exon            146..350
                     /gene="Hbz"
                     /gene_synonym="Glne1; RGD1307486"
                     /inference="alignment:Splign:2.1.0"
     exon            351..589
                     /gene="Hbz"
                     /gene_synonym="Glne1; RGD1307486"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cttgagttca ttcagctcta gcacagcctc cagcctttac cgccgccacc atgtctctga
       61 tgaagaatga gagagctatc atcatgtcca tgtgggacaa aatggcgcct catgcagagc
      121 ccattggcac tgagactctg gagaggctct tcagcagcta cccccagacg aagacctact
      181 tcccacactt cgacctgcac catgggtctc agcagttgcg tgcccacggc tccaagatct
      241 tggccgctgt gggtgatgcg gttaagaaca tcgacaacct ctctggtgct ttgactaagt
      301 tgagcgagct acacgcctac atcctgcgtg tggacccggt caacttcaag ctcctgtctc
      361 actgtctgct ggtcacactg gctgcacact tccccgccga ctttacccct gaggtccacg
      421 aagcttggga caagttcatg tccatcctgt cttctgtcct gactgagaag taccgctaag
      481 tgccatcgcc gcgagtccaa gaccagctat gacctctttc ctccccttca ttgaaccctc
      541 cctgaggtct ttcccagaat ccccaataaa tggttgacga aagaaataa
//
