LOCUS       NM_001024805             444 bp    mRNA    linear   ROD 21-MAR-2023
DEFINITION  Rattus norvegicus hemoglobin, epsilon 2 (Hbe2), mRNA.
ACCESSION   NM_001024805 XM_577830
VERSION     NM_001024805.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Satoh H, Inokuchi N, Nagae Y and Okazaki T.
  TITLE     Molecular cloning and characterization of two sets of alpha-theta
            genes in the rat alpha-like globin gene cluster
  JOURNAL   Gene 230 (1), 91-99 (1999)
   PUBMED   10196478
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Iwahara SI, Abe Y and Okazaki T.
  TITLE     Identification of five embryonic hemoglobins of rat and ontogeny of
            their constituent globins during fetal development
  JOURNAL   J Biochem 119 (2), 360-366 (1996)
   PUBMED   8882731
REFERENCE   3  (bases 1 to 444)
  AUTHORS   Kohli-Kumar M, Zwerdling T and Rucknagel DL.
  TITLE     Hemoglobin F-Cincinnati, alpha 2G gamma 2 41(C7) Phe-->Ser in a
            newborn with cyanosis
  JOURNAL   Am J Hematol 49 (1), 43-47 (1995)
   PUBMED   7741137
REFERENCE   4  (bases 1 to 444)
  AUTHORS   Miller,B.A., Olivieri,N., Salameh,M., Ahmed,M., Antognetti,G.,
            Huisman,T.H., Nathan,D.G. and Orkin,S.H.
  TITLE     Molecular analysis of the high-hemoglobin-F phenotype in Saudi
            Arabian sickle cell anemia
  JOURNAL   N Engl J Med 316 (5), 244-250 (1987)
   PUBMED   2432426
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from X56327.1.
            
            On Jun 10, 2005 this sequence version replaced XM_577830.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMN06680427,
                              SAMN06680431 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="W"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q32"
     gene            1..444
                     /gene="Hbe2"
                     /gene_synonym="Glnb3"
                     /note="hemoglobin, epsilon 2"
                     /db_xref="GeneID:502359"
                     /db_xref="RGD:1564524"
     CDS             1..444
                     /gene="Hbe2"
                     /gene_synonym="Glnb3"
                     /note="epsilon 2 globin; globin b3"
                     /codon_start=1
                     /product="hemoglobin subunit epsilon"
                     /protein_id="NP_001019976.1"
                     /db_xref="GeneID:502359"
                     /db_xref="RGD:1564524"
                     /translation="MVHFTAEEKAAIISIWEKVDLEKLGGETLGRLLIVYPWTQRFFD
                     KFGNLSSAPAIMGNPQIRAHGKKVLVSLGLAVENMDNLKETFAHLSELHCDKLHVDPE
                     NFKLLGNVLVIVLSSYFGKEFTAEVQAAWQKLVAGVATALSHKYH"
     exon            1..92
                     /gene="Hbe2"
                     /gene_synonym="Glnb3"
                     /inference="alignment:Splign:2.1.0"
     exon            93..315
                     /gene="Hbe2"
                     /gene_synonym="Glnb3"
                     /inference="alignment:Splign:2.1.0"
     exon            316..444
                     /gene="Hbe2"
                     /gene_synonym="Glnb3"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atggttcact tcacagctga ggagaaggct gctatcataa gcatatggga aaaagtggac
       61 ttggaaaaac ttggaggaga aaccctggga aggctcctca ttgtatatcc atggactcag
      121 agattctttg acaagtttgg aaacctctct tctgctccgg ccatcatggg taatccccag
      181 atcagagccc atggcaagaa agtgctggtg tccctaggct tggcagttga gaacatggac
      241 aacctcaagg agacctttgc tcatctgagt gagctgcact gtgacaagct tcacgtggat
      301 cccgagaact ttaagctcct gggtaacgtg ctggtgattg ttctttcttc ttacttcggc
      361 aaagaattca cagctgaggt gcaggctgcc tggcagaagc tggtggctgg ggtggccact
      421 gctctgtccc acaagtacca ctga
//
