LOCUS       NM_198776                623 bp    mRNA    linear   ROD 29-MAR-2024
DEFINITION  Rattus norvegicus hemoglobin, beta adult major chain (Hbb-b1),
            mRNA.
ACCESSION   NM_198776 XM_341897
VERSION     NM_198776.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 623)
  AUTHORS   Bastos-Amador,P., Royo,F., Gonzalez,E., Conde-Vancells,J.,
            Palomo-Diez,L., Borras,F.E. and Falcon-Perez,J.M.
  TITLE     Proteomic analysis of microvesicles from plasma of healthy donors
            reveals high individual variability
  JOURNAL   J Proteomics 75 (12), 3574-3584 (2012)
   PUBMED   22516433
REFERENCE   2  (bases 1 to 623)
  AUTHORS   Au,D.M., Wong,W.M., Tam,J.W., Cheng,L.Y. and Lam,V.M.
  TITLE     Genomic organization and characterization of a three-gene rat adult
            beta-globin haplotype
  JOURNAL   Gene 165 (2), 261-266 (1995)
   PUBMED   8522187
REFERENCE   3  (bases 1 to 623)
  AUTHORS   Inokuchi,N.
  TITLE     [Isolation and characterization of three rat adult type beta-globin
            genes]
  JOURNAL   Nihon Ika Daigaku Zasshi 61 (6), 620-632 (1994)
   PUBMED   7829656
REFERENCE   4  (bases 1 to 623)
  AUTHORS   Paunesku,T., Stevanovic,M., Radosavljevic,D., Drmanac,R. and
            Crkvenjakov,R.
  TITLE     Origin of rat beta-globin haplotypes containing three and five
            genes
  JOURNAL   Mol Biol Evol 7 (5), 407-422 (1990)
   PUBMED   2263193
REFERENCE   5  (bases 1 to 623)
  AUTHORS   Crkvenjakov,R., Bucan,M., Konstantinovic,M., Fogel,M., Savic,A. and
            Glisin,V.
  TITLE     Characterization of two rat globin cDNA clones
  JOURNAL   Hemoglobin 8 (6), 597-611 (1984)
   PUBMED   6098570
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000001.1.
            
            On Nov 27, 2020 this sequence version replaced NM_198776.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC058502.1, CB567270.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN16676784, SAMN16676785
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-144               JAXUCZ010000001.1  167643377-167643520 c
            145-367             JAXUCZ010000001.1  167643035-167643257 c
            368-623             JAXUCZ010000001.1  167636064-167636319 c
FEATURES             Location/Qualifiers
     source          1..623
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q32"
     gene            1..623
                     /gene="Hbb-b1"
                     /gene_synonym="Glna1"
                     /note="hemoglobin, beta adult major chain"
                     /db_xref="GeneID:361619"
                     /db_xref="RGD:1595848"
     exon            1..144
                     /gene="Hbb-b1"
                     /gene_synonym="Glna1"
                     /inference="alignment:Splign:2.1.0"
     CDS             53..496
                     /gene="Hbb-b1"
                     /gene_synonym="Glna1"
                     /note="hemoglobin beta-chain; beta-glo; globin a1;
                     hemoglobin subunit beta-2-like"
                     /codon_start=1
                     /product="hemoglobin, beta adult major chain"
                     /protein_id="NP_942071.2"
                     /db_xref="GeneID:361619"
                     /db_xref="RGD:1595848"
                     /translation="MVHLTDAEKATVNGLWGKVNPVEIGAESLASLLIVYPWTQRYFS
                     KFGDLSSVSAIMGNPQVKAHGKKVINAFDDGLKHLDNLKGTFGSLSELHCDKLHVDPE
                     NFRLLGNMIVIMMGHHLGKEFTPSAQAAFQKVVAGVASALAHKYH"
     exon            145..367
                     /gene="Hbb-b1"
                     /gene_synonym="Glna1"
                     /inference="alignment:Splign:2.1.0"
     exon            368..623
                     /gene="Hbb-b1"
                     /gene_synonym="Glna1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atatttgctt ctgatactgt tgtgttgact cgcaacctca ggaacagaca ccatggtgca
       61 cctaactgat gctgagaagg ctactgttaa tggcctgtgg ggaaaggtga accctgttga
      121 aattggcgct gagtcccttg ccagtctgct tattgtctac ccttggaccc agaggtactt
      181 ttctaaattt ggggacctgt cctctgtctc tgctatcatg ggtaaccccc aggtgaaggc
      241 ccatggcaaa aaggtgataa acgccttcga tgatggcctg aaacacttgg acaacctcaa
      301 gggcaccttt ggcagcctca gtgaactcca ctgtgacaag ctgcatgtgg atcctgagaa
      361 cttcaggctc ctgggcaata tgattgtgat tatgatgggc caccacctgg gcaaagaatt
      421 caccccgagt gcacaggctg ccttccagaa ggtggtggct ggagtggcca gtgccctggc
      481 tcacaagtac cactaaacct cttttcctgc tcttgtcttt gttcaatggt caattgttcc
      541 caagagagct tctgtcagtt gttgtcaaaa tgacaaagac ctttgaaaat ctgtcctact
      601 aattaaaggc atttactttc act
//
