LOCUS       NM_138864               1598 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus HAUS augmin-like complex, subunit 1 (Haus1),
            mRNA.
ACCESSION   NM_138864
VERSION     NM_138864.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1598)
  AUTHORS   Jakobsen,L., Vanselow,K., Skogs,M., Toyoda,Y., Lundberg,E.,
            Poser,I., Falkenby,L.G., Bennetzen,M., Westendorf,J., Nigg,E.A.,
            Uhlen,M., Hyman,A.A. and Andersen,J.S.
  TITLE     Novel asymmetrically localizing components of human centrosomes
            identified by complementary proteomics methods
  JOURNAL   EMBO J 30 (8), 1520-1535 (2011)
   PUBMED   21399614
REFERENCE   2  (bases 1 to 1598)
  AUTHORS   Lawo,S., Bashkurov,M., Mullin,M., Ferreria,M.G., Kittler,R.,
            Habermann,B., Tagliaferro,A., Poser,I., Hutchins,J.R., Hegemann,B.,
            Pinchev,D., Buchholz,F., Peters,J.M., Hyman,A.A., Gingras,A.C. and
            Pelletier,L.
  TITLE     HAUS, the 8-subunit human Augmin complex, regulates centrosome and
            spindle integrity
  JOURNAL   Curr Biol 19 (10), 816-826 (2009)
   PUBMED   19427217
REFERENCE   3  (bases 1 to 1598)
  AUTHORS   Uehara,R., Nozawa,R.S., Tomioka,A., Petry,S., Vale,R.D., Obuse,C.
            and Goshima,G.
  TITLE     The augmin complex plays a critical role in spindle microtubule
            generation for mitotic progression and cytokinesis in human cells
  JOURNAL   Proc Natl Acad Sci U S A 106 (17), 6998-7003 (2009)
   PUBMED   19369198
REFERENCE   4  (bases 1 to 1598)
  AUTHORS   Einarson,M.B., Cukierman,E., Compton,D.A. and Golemis,E.A.
  TITLE     Human enhancer of invasion-cluster, a coiled-coil protein required
            for passage through mitosis
  JOURNAL   Mol Cell Biol 24 (9), 3957-3971 (2004)
   PUBMED   15082789
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC127484.1.
            
            On Jun 10, 2007 this sequence version replaced NM_138864.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC127484.1, AF092207.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760389
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1598
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="18"
                     /map="18q12.3"
     gene            1..1598
                     /gene="Haus1"
                     /gene_synonym="Ccdc5"
                     /note="HAUS augmin-like complex, subunit 1"
                     /db_xref="GeneID:192228"
                     /db_xref="RGD:619909"
     exon            1..45
                     /gene="Haus1"
                     /gene_synonym="Ccdc5"
                     /inference="alignment:Splign:2.1.0"
     CDS             16..852
                     /gene="Haus1"
                     /gene_synonym="Ccdc5"
                     /note="coiled-coil domain-containing protein 5;
                     coiled-coil domain containing 5; HAUS augmin-like complex
                     subunit 1-like"
                     /codon_start=1
                     /product="HAUS augmin-like complex subunit 1"
                     /protein_id="NP_620219.2"
                     /db_xref="GeneID:192228"
                     /db_xref="RGD:619909"
                     /translation="MAALEEKASQVAEWLKKIFGDHPIPQYEMNARTTEILYHLSERN
                     RVRDRDVNLVIEDLRQKASEYESEAKRLEDFLMESVNFSPANLSNTGSRFLNALVDSA
                     IALEIKDTSLASFIPAVNDLTSDLFRTKSKSEEIKLELGKLEKNLTATLVLEKCLRED
                     LKKADVHLSAERAKAEGRLQNMDFLKAKAAEFRFGIRAAEEQLSSRGMDASLSHRSLV
                     ALSDKLSELKQQTIPLKKKLESYLDLMPNPSLAQVKIEEAKRELDAIEAELTKKVDMM
                     EL"
     exon            46..220
                     /gene="Haus1"
                     /gene_synonym="Ccdc5"
                     /inference="alignment:Splign:2.1.0"
     exon            221..356
                     /gene="Haus1"
                     /gene_synonym="Ccdc5"
                     /inference="alignment:Splign:2.1.0"
     exon            357..491
                     /gene="Haus1"
                     /gene_synonym="Ccdc5"
                     /inference="alignment:Splign:2.1.0"
     exon            492..615
                     /gene="Haus1"
                     /gene_synonym="Ccdc5"
                     /inference="alignment:Splign:2.1.0"
     exon            616..681
                     /gene="Haus1"
                     /gene_synonym="Ccdc5"
                     /inference="alignment:Splign:2.1.0"
     exon            682..753
                     /gene="Haus1"
                     /gene_synonym="Ccdc5"
                     /inference="alignment:Splign:2.1.0"
     exon            754..801
                     /gene="Haus1"
                     /gene_synonym="Ccdc5"
                     /inference="alignment:Splign:2.1.0"
     exon            802..1574
                     /gene="Haus1"
                     /gene_synonym="Ccdc5"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcgggagcgg cggctatggc ggcgctggag gagaaagcat cacaggtcgc tgagtggttg
       61 aaaaagatat ttggagacca tcccattcca caatatgaga tgaacgcacg gacgacagaa
      121 attttatatc acctttcaga acgcaacagg gtccgggaca gggacgtcaa cctggtaata
      181 gaggacttaa gacagaaagc gagtgaatat gagtcggaag ccaaacgtct tgaagacttt
      241 ctcatggaga gtgtgaattt ttcccctgcc aatctgtcaa acactggttc ccggtttctg
      301 aatgcattgg tggacagtgc aattgccctg gaaataaaag atacgtcact agcaagtttt
      361 atccccgcag tgaacgattt gacttctgac ctttttcgta ccaaatccaa aagtgaagaa
      421 atcaagcttg aactggggaa acttgaaaag aatctgacgg caacgttggt gttagaaaaa
      481 tgtctccgag aagacctcaa gaaagcagat gtgcacctgt ctgcagaaag ggccaaagcc
      541 gagggccgcc tccagaacat ggacttcctg aaagccaagg cggcggagtt ccggtttggg
      601 atccgagctg cagaggagca actttcatcc agaggcatgg acgcgtccct gtctcatcgg
      661 tcactagtgg cactttcaga caaactttcg gaattaaaac agcagactat ccctctgaag
      721 aagaaattgg agtcctattt agatctaatg ccgaatccat ctcttgctca ggtgaaaatt
      781 gaagaggcaa agagagaatt agatgccatc gaggctgaac tcacaaagaa agtagatatg
      841 atggagctgt gaggacgcca agtagatgcc tctcctgaga aggagatgac agttcttaga
      901 gacaataatg tctttattgg taaaataaca gggcttggtt ctgcatttac attttgtggc
      961 ctgaatacag ttttcctatg aaaaggcact ttctttctgt tacctgctac ttcctgcaca
     1021 cctcgcagtt aagaatcttc ccgaaagcgg gtaggggctg gggcaacggc tctgcatttt
     1081 agagcacttt ttgctcttgc tgaagacctg ggttctattc tcagcgccca tatggtgagg
     1141 cttgaaaaca cctatgacta gtgccacaca cacaccctcc tctagcatct gcaagcgcca
     1201 ggcacacatg tggcacacag acgtacgtac aggcagaata ctcacatgca taaacacttt
     1261 ttaattgaga aaaaggaatc cgtcagcagc tccgttaggt ggccgacgtg acagtactgc
     1321 agacgcacaa tctaggccag tagacagttt gtgtggctcc agtttgtcta cctccttctc
     1381 ttgggctcac gggcctgtct cccaacgtta atacgttatc tcgtgaaaaa agcagccttt
     1441 aagccagtgg cagcaagaga aataataaag caagcatatg gtgctaaatt tatatttcat
     1501 gccttctatt aggataaccc aaagaaatca aagaagacca atataaaaat ttaaataaag
     1561 atactgaact gggaaaaaaa aaaaaaaaaa aaaaaaaa
//
