LOCUS       NM_001009657            1500 bp    mRNA    linear   ROD 01-JUN-2024
DEFINITION  Rattus norvegicus histone acetyltransferase 1 (Hat1), mRNA.
ACCESSION   NM_001009657 XM_215982
VERSION     NM_001009657.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1500)
  AUTHORS   Demyanenko,S.V., Dzreyan,V.A. and Uzdensky,A.B.
  TITLE     The Expression and Localization of Histone Acetyltransferases HAT1
            and PCAF in Neurons and Astrocytes of the Photothrombotic
            Stroke-Induced Penumbra in the Rat Brain Cortex
  JOURNAL   Mol Neurobiol 57 (7), 3219-3227 (2020)
   PUBMED   32506381
  REMARK    GeneRIF: The Expression and Localization of Histone
            Acetyltransferases HAT1 and PCAF in Neurons and Astrocytes of the
            Photothrombotic Stroke-Induced Penumbra in the Rat Brain Cortex.
REFERENCE   2  (bases 1 to 1500)
  AUTHORS   Wu,H., Moshkina,N., Min,J., Zeng,H., Joshua,J., Zhou,M.M. and
            Plotnikov,A.N.
  TITLE     Structural basis for substrate specificity and catalysis of human
            histone acetyltransferase 1
  JOURNAL   Proc Natl Acad Sci U S A 109 (23), 8925-8930 (2012)
   PUBMED   22615379
  REMARK    Erratum:[Proc Natl Acad Sci U S A. 2013 Nov 5;110(45):18339]
REFERENCE   3  (bases 1 to 1500)
  AUTHORS   Peserico,A. and Simone,C.
  TITLE     Physical and functional HAT/HDAC interplay regulates protein
            acetylation balance
  JOURNAL   J Biomed Biotechnol 2011, 371832 (2011)
   PUBMED   21151613
  REMARK    Review article
REFERENCE   4  (bases 1 to 1500)
  AUTHORS   Dejardin,J. and Kingston,R.E.
  TITLE     Purification of proteins associated with specific genomic Loci
  JOURNAL   Cell 136 (1), 175-186 (2009)
   PUBMED   19135898
REFERENCE   5  (bases 1 to 1500)
  AUTHORS   Pogribny,I.P., Tryndyak,V.P., Muskhelishvili,L., Rusyn,I. and
            Ross,S.A.
  TITLE     Methyl deficiency, alterations in global histone modifications, and
            carcinogenesis
  JOURNAL   J Nutr 137 (1 Suppl), 216S-222S (2007)
   PUBMED   17182829
REFERENCE   6  (bases 1 to 1500)
  AUTHORS   Tagami,H., Ray-Gallet,D., Almouzni,G. and Nakatani,Y.
  TITLE     Histone H3.1 and H3.3 complexes mediate nucleosome assembly
            pathways dependent or independent of DNA synthesis
  JOURNAL   Cell 116 (1), 51-61 (2004)
   PUBMED   14718166
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC087663.1.
            
            On Jan 13, 2005 this sequence version replaced XM_215982.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC087663.1, SRR8487226.199664.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1500
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="3"
                     /map="3q23"
     gene            1..1500
                     /gene="Hat1"
                     /note="histone acetyltransferase 1"
                     /db_xref="GeneID:296501"
                     /db_xref="RGD:1305716"
     exon            1..45
                     /gene="Hat1"
                     /inference="alignment:Splign:2.1.0"
     CDS             39..1298
                     /gene="Hat1"
                     /EC_number="2.3.1.48"
                     /note="histone aminotransferase 1"
                     /codon_start=1
                     /product="histone acetyltransferase type B catalytic
                     subunit"
                     /protein_id="NP_001009657.1"
                     /db_xref="GeneID:296501"
                     /db_xref="RGD:1305716"
                     /translation="MAGFGAMEKFLVEYKSAVEKKLAEYKCNTNTAIELKLVRFPEDL
                     ENDIRTFFPEYTHQLFGDDETAFGYKGLKILLYYIAGSLSTMFRVEYASKVDENFDCV
                     EADDVEGKIRQIIPPGFCTNTNDFLSLLEKEADFKPFGTLLHTYSVPSPTGGENFTFQ
                     IYKADMTCRGFREYHERLQTFLMWFIETASFIDVDDERWHYFLVFEKYNKDGATLFAT
                     VGYMTVYNYYVYPDKTRPRVSQMLILTPFQGQGHGAQLLETVHRYYIASSSVLDITAE
                     DPSKSYVKLRDFVLVKLCQDLPCFSRERLLQGFNEDMAIQAQQKFKINKQHARRVYEI
                     LRLLVTDMSDAEQCRSYRLDIKRRLISPYKKKQTDLAKMRKCLRPEELTNQMNQIEIS
                     VQHEQLEEQFQELVEDYRRVIERLAQE"
     exon            46..150
                     /gene="Hat1"
                     /inference="alignment:Splign:2.1.0"
     exon            151..226
                     /gene="Hat1"
                     /inference="alignment:Splign:2.1.0"
     exon            227..347
                     /gene="Hat1"
                     /inference="alignment:Splign:2.1.0"
     exon            348..527
                     /gene="Hat1"
                     /inference="alignment:Splign:2.1.0"
     exon            528..649
                     /gene="Hat1"
                     /inference="alignment:Splign:2.1.0"
     exon            650..754
                     /gene="Hat1"
                     /inference="alignment:Splign:2.1.0"
     exon            755..861
                     /gene="Hat1"
                     /inference="alignment:Splign:2.1.0"
     exon            862..1013
                     /gene="Hat1"
                     /inference="alignment:Splign:2.1.0"
     exon            1014..1130
                     /gene="Hat1"
                     /inference="alignment:Splign:2.1.0"
     exon            1131..1477
                     /gene="Hat1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tttgtccttc ctcagccgcg ggcgctcaga gctcggaaat ggcggggttt ggtgcaatgg
       61 agaaatttct agtggaatat aagagtgcgg tggagaagaa actggctgag tacaagtgta
      121 acaccaacac agcaatcgag ctgaaactgg ttcgttttcc tgaagatctt gagaatgaca
      181 ttagaacttt ctttcctgaa tatacccatc aactctttgg ggatgatgaa actgcttttg
      241 gttacaaggg cctgaagatc ttgttgtact atattgctgg tagcctgtca actatgttcc
      301 gtgttgaata tgcatctaaa gttgatgaga actttgattg tgtggaggca gatgacgttg
      361 aaggcaaaat cagacaaatc attccacctg ggttttgcac aaacacaaat gattttcttt
      421 ccttgctgga aaaggaagct gatttcaagc catttggaac cctcctccat acatactcag
      481 ttcctagtcc aacaggagga gaaaacttta cttttcagat atacaaggct gacatgacat
      541 gtagaggctt tcgagaatat catgaaaggc ttcagacctt tttgatgtgg tttattgaaa
      601 ctgctagctt tattgacgtg gatgatgaaa gatggcacta ctttctagta tttgagaagt
      661 ataataagga tggagctacg ctctttgcga ccgtaggcta catgacagtc tataattact
      721 atgtgtaccc agacaaaacc cggccacgtg taagtcagat gctgatactg actccatttc
      781 aaggtcaggg ccatggtgct caacttcttg aaacagttca tagatactac attgcatctt
      841 cttcagttct tgatattaca gcggaagatc catccaaaag ctatgtgaaa ctaagagact
      901 ttgtacttgt gaaactttgt caagatttgc cctgtttctc ccgggaaaga ttactgcaag
      961 gattcaatga agatatggcg atacaggcac agcagaagtt caaaataaat aagcaacatg
     1021 ctagacgggt ttatgaaatt ctccgactgc tggtgactga catgagtgac gcggagcagt
     1081 gcagaagcta cagactggat attaaaagga gactaatcag cccttacaag aaaaagcaga
     1141 cagatcttgc caagatgagg aaatgcctga gaccagaaga gctgacgaat cagatgaacc
     1201 agatagagat aagtgtgcag cacgagcagc tggaggagca gtttcaggag ctggtggagg
     1261 actaccggcg tgtcattgag cgccttgctc aagagtgaag cccttgttcc ctggatacct
     1321 gcgatttctg tgcattgtgc tgtgaaacct ctgatgaccc taaagttatc tatgttctcc
     1381 ttagtggaat atttcctttt gagagattgt atattttaaa atactgtcta gagtttatga
     1441 acatatattg cattaataaa agatggcttg tgaaataaaa aaaaaaaaaa aaaaaaaaaa
//
