LOCUS       NM_001008559            1338 bp    mRNA    linear   ROD 29-MAR-2024
DEFINITION  Rattus norvegicus hyaluronan and proteoglycan link protein 3
            (Hapln3), mRNA.
ACCESSION   NM_001008559 XM_218832
VERSION     NM_001008559.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1338)
  AUTHORS   Palmer,D.J., Kelly,V.C., Smit,A.M., Kuy,S., Knight,C.G. and
            Cooper,G.J.
  TITLE     Human colostrum: identification of minor proteins in the aqueous
            phase by proteomics
  JOURNAL   Proteomics 6 (7), 2208-2216 (2006)
   PUBMED   16502470
REFERENCE   2  (bases 1 to 1338)
  AUTHORS   Ogawa,H., Oohashi,T., Sata,M., Bekku,Y., Hirohata,S., Nakamura,K.,
            Yonezawa,T., Kusachi,S., Shiratori,Y. and Ninomiya,Y.
  TITLE     Lp3/Hapln3, a novel link protein that co-localizes with versican
            and is coordinately up-regulated by platelet-derived growth factor
            in arterial smooth muscle cells
  JOURNAL   Matrix Biol 23 (5), 287-298 (2004)
   PUBMED   15464361
  REMARK    GeneRIF: Lp3/Hapln3 is involved, together with versican and
            hyaluronan, in the formation of the pericellular matrix of vascular
            smooth muscle cells.
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000001.1.
            
            On Nov 27, 2020 this sequence version replaced NM_001008559.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AB186131.1, SRR26360190.2381592.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760389
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-189               JAXUCZ010000001.1  142463512-142463700 c
            190-558             JAXUCZ010000001.1  142460211-142460579 c
            559-861             JAXUCZ010000001.1  142457000-142457302 c
            862-1338            JAXUCZ010000001.1  142455828-142456304 c
FEATURES             Location/Qualifiers
     source          1..1338
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q31"
     gene            1..1338
                     /gene="Hapln3"
                     /note="hyaluronan and proteoglycan link protein 3"
                     /db_xref="GeneID:308773"
                     /db_xref="RGD:1308098"
     exon            1..189
                     /gene="Hapln3"
                     /inference="alignment:Splign:2.1.0"
     CDS             66..1145
                     /gene="Hapln3"
                     /EC_number="3.1.2.15"
                     /codon_start=1
                     /product="hyaluronan and proteoglycan link protein 3
                     precursor"
                     /protein_id="NP_001008559.1"
                     /db_xref="GeneID:308773"
                     /db_xref="RGD:1308098"
                     /translation="MGLLFLVLLSPLSCVLGLPFYNGFYYSNGLHGRTLGNGYGEGLF
                     NGVKLVVETTEESLFSHQGASVTLPCHYHYEPALASPRHVRIKWWKLSENGTPEQDVL
                     VAIGQRHRSFGDYQGRVQLRQDKEQEVSLELRDLRLEDSGRYRCEVIDGLEDESGLVE
                     LELRGVVFPYQPREGRYQLNFHEAQQVCQEQDAVVATFEQLFRAWEEGLDWCNAGWLQ
                     DASVQYPIVLPRQPCGGLGLAPGVRSYGQRHHRLHRYDVFCFAAALKGRVYYLENPEK
                     LTLLEAREACQEDGAQISTVGQLFAAWKFRGLDRCDAGWLADGSARYPIIHPRPNCGP
                     PEPGVRTFGFPDPNTRYGVYCYHQH"
     exon            190..558
                     /gene="Hapln3"
                     /inference="alignment:Splign:2.1.0"
     exon            559..861
                     /gene="Hapln3"
                     /inference="alignment:Splign:2.1.0"
     exon            862..1338
                     /gene="Hapln3"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tctgcagttt tcccagggcc cagcctcatc caagataccc tggcattgcc accatcccgg
       61 ccaggatggg cctgctgttc cttgtccttc tttcaccact ttcctgtgtt ttgggacttc
      121 cgttctacaa cggcttctac tattccaacg gtctgcatgg caggaccctg ggcaatggct
      181 atggagaagg cctattcaat ggcgtgaagt tagtggtgga gaccaccgag gagtcgttgt
      241 tcagtcacca aggagccagt gtgaccctgc cctgccacta ccactatgag ccagccctgg
      301 catctccgag acatgtgcgt attaagtggt ggaagttgtc agagaatgga accccggagc
      361 aagacgtgct ggtggccatc gggcagaggc accgctcctt tggggactac caagggcgag
      421 ttcaattgag gcaggacaag gagcaggagg tctcactgga gcttcgagac ctgcggctgg
      481 aggactctgg gcgctaccgc tgtgaggtca ttgacggtct ggaagatgag agtggcctgg
      541 tagagctgga gctgcggggt gtggtttttc cctaccagcc ccgagaaggg cgctaccagc
      601 tcaatttcca tgaggcccaa caggtctgcc aggagcagga tgctgtggta gccacttttg
      661 agcagctttt ccgagcgtgg gaggaaggcc tagactggtg caatgcaggc tggctacagg
      721 atgcctccgt gcagtaccct atagtgctgc cccggcagcc ctgtggaggc ctgggtctgg
      781 cacctggggt tcgcagctac ggccagcgcc atcaccgcct gcatcgctat gacgtgttct
      841 gctttgctgc tgccctcaag gggcgagtgt actacctgga gaaccctgag aaactgacgc
      901 tgctggaggc cagggaggcc tgtcaggaag atggtgcgca gatctctacg gtgggtcagc
      961 tctttgctgc ttggaagttc cgtggcctgg atcgttgtga tgctggctgg ctggcagacg
     1021 gaagtgcccg ctaccccatc attcaccccc gacccaactg cggcccacct gaacctggag
     1081 tacgaacctt tggcttccca gaccccaaca cccgctacgg tgtctactgt taccaccagc
     1141 actagcagag tgacaagctg tatatctgcc ctgcccctaa ctttcgggac ttagtgttta
     1201 tcaggtggac cattgtccct tgtgggttgg ggaacttctt ggattgtttt tatacttccc
     1261 aacttaaaca tttaaagtta ttattattat tattattatt attattatta ttattattat
     1321 tacaggacca actcttaa
//
