LOCUS       NM_022285               1384 bp    mRNA    linear   ROD 30-MAR-2024
DEFINITION  Rattus norvegicus hyaluronan and proteoglycan link protein 2
            (Hapln2), mRNA.
ACCESSION   NM_022285 XM_342274
VERSION     NM_022285.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1384)
  AUTHORS   Bekku,Y., Vargova,L., Goto,Y., Vorisek,I., Dmytrenko,L.,
            Narasaki,M., Ohtsuka,A., Fassler,R., Ninomiya,Y., Sykova,E. and
            Oohashi,T.
  TITLE     Bral1: its role in diffusion barrier formation and conduction
            velocity in the CNS
  JOURNAL   J Neurosci 30 (8), 3113-3123 (2010)
   PUBMED   20181608
REFERENCE   2  (bases 1 to 1384)
  AUTHORS   Oohashi,T., Hirakawa,S., Bekku,Y., Rauch,U., Zimmermann,D.R.,
            Su,W.D., Ohtsuka,A., Murakami,T. and Ninomiya,Y.
  TITLE     Bral1, a brain-specific link protein, colocalizing with the
            versican V2 isoform at the nodes of Ranvier in developing and adult
            mouse central nervous systems
  JOURNAL   Mol Cell Neurosci 19 (1), 43-57 (2002)
   PUBMED   11817897
REFERENCE   3  (bases 1 to 1384)
  AUTHORS   Hirakawa,S., Oohashi,T., Su,W.D., Yoshioka,H., Murakami,T.,
            Arata,J. and Ninomiya,Y.
  TITLE     The brain link protein-1 (BRAL1): cDNA cloning, genomic structure,
            and characterization as a novel link protein expressed in adult
            brain
  JOURNAL   Biochem Biophys Res Commun 276 (3), 982-989 (2000)
   PUBMED   11027579
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000002.1.
            
            On Nov 27, 2020 this sequence version replaced NM_022285.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AB049056.1, SRR26643298.11733.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760389 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-74                JAXUCZ010000002.1  175794365-175794438 c
            75-130              JAXUCZ010000002.1  175793950-175794005 c
            131-272             JAXUCZ010000002.1  175790974-175791115 c
            273-626             JAXUCZ010000002.1  175790409-175790762 c
            627-743             JAXUCZ010000002.1  175790169-175790285 c
            744-926             JAXUCZ010000002.1  175789854-175790036 c
            927-1384            JAXUCZ010000002.1  175789009-175789466 c
FEATURES             Location/Qualifiers
     source          1..1384
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="2"
                     /map="2q34"
     gene            1..1384
                     /gene="Hapln2"
                     /gene_synonym="Bral1"
                     /note="hyaluronan and proteoglycan link protein 2"
                     /db_xref="GeneID:64057"
                     /db_xref="RGD:621854"
     exon            1..74
                     /gene="Hapln2"
                     /gene_synonym="Bral1"
                     /inference="alignment:Splign:2.1.0"
     exon            75..130
                     /gene="Hapln2"
                     /gene_synonym="Bral1"
                     /inference="alignment:Splign:2.1.0"
     exon            131..272
                     /gene="Hapln2"
                     /gene_synonym="Bral1"
                     /inference="alignment:Splign:2.1.0"
     CDS             185..1210
                     /gene="Hapln2"
                     /gene_synonym="Bral1"
                     /note="brain link protein 1"
                     /codon_start=1
                     /product="hyaluronan and proteoglycan link protein 2
                     precursor"
                     /protein_id="NP_071621.2"
                     /db_xref="GeneID:64057"
                     /db_xref="RGD:621854"
                     /translation="MPSWIPLPAFCCLLLPWAFTVFHKTLGNPAPHPGPHYLLPPIHE
                     VIHSRRGATATLPCVLGTSPPSYKVRWSKVEPGELRETLILITNGLHARDYGLLGGRA
                     SLRRGHRLDASLIIKNVRLEDEGRYRCELINGIEDESVALTLRLEGVVFPYQPSRGRY
                     QFNYFEAKRACEEQDGRLATYSQLYQAWTEGLDWCNAGWLLEGSVRYPVLNARAPCGG
                     HGRPGIRSYGPRDRSRDRYDAFCFTSALAGQVFFVPGRLTLSEAHAACRRRGAVVAKV
                     GHLYAAWKFSGLDRCDGGWLADGSVRFPITTPRPRCGGLPDPGVRSFGFPRPQQAAYG
                     TYCYAEK"
     exon            273..626
                     /gene="Hapln2"
                     /gene_synonym="Bral1"
                     /inference="alignment:Splign:2.1.0"
     exon            627..743
                     /gene="Hapln2"
                     /gene_synonym="Bral1"
                     /inference="alignment:Splign:2.1.0"
     exon            744..926
                     /gene="Hapln2"
                     /gene_synonym="Bral1"
                     /inference="alignment:Splign:2.1.0"
     exon            927..1384
                     /gene="Hapln2"
                     /gene_synonym="Bral1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 catcctgaaa gtctgattcc catcttgaga gcctcttccg aaaggccata tgtggcctgg
       61 cacagagggc acaggacagg aagctgctga gcactgctcc ctttgcctct gaggagagat
      121 catcttgcag tactaaggcg tgcctatcaa ctgtgccctg cagacagtgc ttgctgacat
      181 caccatgcca agctggatcc ctctccctgc gttctgctgc ctccttctcc cctgggcctt
      241 caccgtcttt cacaaaaccc tggggaaccc cgccccccat ccgggtcccc actacctcct
      301 gccccccatc cacgaggtca ttcactctcg tcgtggggcc acggccacac tgccctgcgt
      361 cctgggcacc tcgcctccca gctacaaagt acgctggagc aaagtggagc ccggggagct
      421 ccgggaaacg ctaatcctca tcaccaacgg actgcacgcc cgggactacg ggctcctggg
      481 agggcgcgcc agcttgcgga gagggcatcg gctggacgcc tccctgatca tcaagaacgt
      541 gcgtctggaa gatgagggtc ggtaccgctg cgagctcatc aatggcatcg aggacgagag
      601 cgtggcactg accctgcgcc tggagggtgt ggtgtttccg taccaaccca gccggggccg
      661 ctaccagttc aattacttcg aggcgaagcg ggcgtgtgag gagcaggacg gacgcctggc
      721 cacttacagc caactctacc aggcgtggac cgaggggctg gactggtgca acgccggttg
      781 gttgctcgag ggctccgtgc gctaccctgt gctcaacgcg cgggctccat gcggcggcca
      841 cgggcggcca ggcatccgca gctacgggcc ccgcgaccgc agccgcgacc gctacgacgc
      901 cttctgcttc acctcggccc tggcaggcca ggtcttcttc gtgcctggac ggctgacgtt
      961 gtccgaagcc cacgcggctt gccggcggcg cggagctgta gtagccaagg tcgggcacct
     1021 ctacgccgcc tggaagttct cggggctgga tcggtgcgac ggaggctggc tggcggacgg
     1081 cagcgttcgc ttccccatca ccacgccgcg gccgcgctgc gggggtctcc ctgaccccgg
     1141 ggtgcgcagc ttcggctttc cccggcccca gcaggcggcc tacgggacct actgctatgc
     1201 cgaaaagtag cagtgcattg ccctgccacg cgcgacagag tggcgggtcc cctctggaca
     1261 gacgagggct gagcccccct cacctgcctt cccaggcagc gagatgctct gggctcctgg
     1321 gtaaaggggc ttcctgggca ttaactgacc aataaaataa catggcacct tctttgttcg
     1381 ataa
//
