LOCUS       NM_001402103            1010 bp    mRNA    linear   ROD 01-APR-2024
DEFINITION  Rattus norvegicus 3-hydroxyacyl-CoA dehydratase 2 (Hacd2),
            transcript variant 1, mRNA.
ACCESSION   NM_001402103 XM_039088913
VERSION     NM_001402103.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1010)
  AUTHORS   Ikeda,M., Kanao,Y., Yamanaka,M., Sakuraba,H., Mizutani,Y.,
            Igarashi,Y. and Kihara,A.
  TITLE     Characterization of four mammalian 3-hydroxyacyl-CoA dehydratases
            involved in very long-chain fatty acid synthesis
  JOURNAL   FEBS Lett 582 (16), 2435-2440 (2008)
   PUBMED   18554506
REFERENCE   2  (bases 1 to 1010)
  AUTHORS   Florea,L., Di Francesco,V., Miller,J., Turner,R., Yao,A.,
            Harris,M., Walenz,B., Mobarry,C., Merkulov,G.V., Charlab,R.,
            Dew,I., Deng,Z., Istrail,S., Li,P. and Sutton,G.
  TITLE     Gene and alternative splicing annotation with AIR
  JOURNAL   Genome Res 15 (1), 54-66 (2005)
   PUBMED   15632090
REFERENCE   3  (bases 1 to 1010)
  AUTHORS   Wang,B., Pelletier,J., Massaad,M.J., Herscovics,A. and Shore,G.C.
  TITLE     The yeast split-ubiquitin membrane protein two-hybrid screen
            identifies BAP31 as a regulator of the turnover of endoplasmic
            reticulum-associated protein tyrosine phosphatase-like B
  JOURNAL   Mol Cell Biol 24 (7), 2767-2778 (2004)
   PUBMED   15024066
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000011.1.
            
            On Mar 4, 2022 this sequence version replaced XM_039088913.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: DY471500.1, CO392805.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN12840105,
                                           SAMN12840107 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-219               JAXUCZ010000011.1  79267908-79268126   c
            220-337             JAXUCZ010000011.1  79264623-79264740   c
            338-356             JAXUCZ010000011.1  79247115-79247133   c
            357-445             JAXUCZ010000011.1  79206617-79206705   c
            446-567             JAXUCZ010000011.1  79182173-79182294   c
            568-746             JAXUCZ010000011.1  79179973-79180151   c
            747-1010            JAXUCZ010000011.1  79175470-79175733   c
FEATURES             Location/Qualifiers
     source          1..1010
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="11"
                     /map="11q22"
     gene            1..1010
                     /gene="Hacd2"
                     /gene_synonym="Ptplb"
                     /note="3-hydroxyacyl-CoA dehydratase 2"
                     /db_xref="GeneID:102551408"
                     /db_xref="RGD:1306337"
     exon            1..219
                     /gene="Hacd2"
                     /gene_synonym="Ptplb"
                     /inference="alignment:Splign:2.1.0"
     CDS             65..829
                     /gene="Hacd2"
                     /gene_synonym="Ptplb"
                     /EC_number="4.2.1.134"
                     /note="very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase
                     2-like; very-long-chain (3R)-3-hydroxyacyl-[acyl-carrier
                     protein] dehydratase 2-like; protein tyrosine
                     phosphatase-like (proline instead of catalytic arginine),
                     member b; protein-tyrosine phosphatase-like member B"
                     /codon_start=1
                     /product="very-long-chain (3R)-3-hydroxyacyl-CoA
                     dehydratase 2"
                     /protein_id="NP_001389032.1"
                     /db_xref="GeneID:102551408"
                     /db_xref="RGD:1306337"
                     /translation="MAAAAATATTKGNGGGSGRAGAGDSSGSRKKKGPGPVATAYLVI
                     YNVVMTAGWLVIAVGLVRAYLAKGSYHSLYYSIEKPLKFFQTGALLEILHCAIGIVPS
                     SVVLTSFQVMSRVFLIWAVTHSVKEVQSEDSVLLFVIAWTITEIIRYSFYTFSLLNHL
                     PYIIKWARYTLFIVLYPMGVTGELLTIYAALPYVRQAGLYSISLPNKYNFSFDYHAFL
                     ILVMISYIPLFPQLYFHMIQQRRKVLSHTEEHKKLE"
     exon            220..337
                     /gene="Hacd2"
                     /gene_synonym="Ptplb"
                     /inference="alignment:Splign:2.1.0"
     exon            338..356
                     /gene="Hacd2"
                     /gene_synonym="Ptplb"
                     /inference="alignment:Splign:2.1.0"
     exon            357..445
                     /gene="Hacd2"
                     /gene_synonym="Ptplb"
                     /inference="alignment:Splign:2.1.0"
     exon            446..567
                     /gene="Hacd2"
                     /gene_synonym="Ptplb"
                     /inference="alignment:Splign:2.1.0"
     exon            568..746
                     /gene="Hacd2"
                     /gene_synonym="Ptplb"
                     /inference="alignment:Splign:2.1.0"
     exon            747..1010
                     /gene="Hacd2"
                     /gene_synonym="Ptplb"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cccctcgcag tacccagtgg gtctgaggtg cacgcgtgag gagagcgggc tgcaggcgct
       61 tgacatggcg gcagcggcgg cgactgcaac gaccaagggg aatgggggcg gcagtggacg
      121 agccggggct ggcgacagca gcggctcccg gaagaagaag ggccccgggc ctgtggccac
      181 ggcgtacctg gtcatctaca atgtggtgat gacggcgggg tggctggtga tagcggttgg
      241 gctggtgaga gcatacctgg ctaaggggag ctaccatagt ctttattatt caatagaaaa
      301 gcctttgaag ttcttccaga caggagcctt actggagatt ttacattgtg ctatagggat
      361 tgtgccatct tctgttgtcc tgacttcttt ccaggtgatg tcaagagttt tcctaatatg
      421 ggcagtgacc catagtgtca aagaggtgca gagtgaagac agtgtacttc tgtttgtcat
      481 tgcctggaca atcacggaaa ttatccgtta ctccttttac acattcagtc tattaaacca
      541 tttgccttac atcatcaagt gggccaggta cacacttttc atcgtgctgt acccaatggg
      601 agtgacggga gagttactca caatatatgc agctctgccc tatgtccggc aggccggcct
      661 gtactccatc agcctaccta acaaatacaa cttctccttt gactaccatg cattcctgat
      721 tctggtcatg atctcctaca ttccactttt cccccagttg tacttccaca tgatacagca
      781 gagaagaaag gtcctttctc acaccgaaga acacaagaag cttgagtagc tctccacacc
      841 accccaaacc aaacttttca atgatcaaaa aatgctgcag actttttgag ttccttagta
      901 agaactattt ttaaaatatt aaatacaaaa gaaaataaaa accaaaatcc agtgtcacat
      961 gggcctggga ttttataaaa aataaaagtg aaaagattaa aaatgcaaaa
//
