LOCUS       NM_022643                470 bp    mRNA    linear   ROD 01-JUN-2024
DEFINITION  Rattus norvegicus H2B clustered histone 1 (H2bc1), mRNA.
ACCESSION   NM_022643
VERSION     NM_022643.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 470)
  AUTHORS   Mahadevan,I.A., Pentakota,S., Roy,R., Bhaduri,U. and Satyanarayana
            Rao,M.R.
  TITLE     TH2BS11ph histone mark is enriched in the unsynapsed axes of the XY
            body and predominantly associates with H3K4me3-containing genomic
            regions in mammalian spermatocytes
  JOURNAL   Epigenetics Chromatin 12 (1), 53 (2019)
   PUBMED   31493790
  REMARK    GeneRIF: TH2BS11ph is predominantly associated with H3K4me3
            positive genomic regions like gene promoters, etc. TH2BS11ph
            modification could act alone or in concert with other histone
            modifications to recruit the appropriate transcription or XY body
            recombination protein machinery at specific genomic loci.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 470)
  AUTHORS   Barral,S., Morozumi,Y., Tanaka,H., Montellier,E., Govin,J., de
            Dieuleveult,M., Charbonnier,G., Coute,Y., Puthier,D., Buchou,T.,
            Boussouar,F., Urahama,T., Fenaille,F., Curtet,S., Hery,P.,
            Fernandez-Nunez,N., Shiota,H., Gerard,M., Rousseaux,S.,
            Kurumizaka,H. and Khochbin,S.
  TITLE     Histone Variant H2A.L.2 Guides Transition Protein-Dependent
            Protamine Assembly in Male Germ Cells
  JOURNAL   Mol Cell 66 (1), 89-101 (2017)
   PUBMED   28366643
REFERENCE   3  (bases 1 to 470)
  AUTHORS   Pentakota,S.K., Sandhya,S., P Sikarwar,A., Chandra,N. and
            Satyanarayana Rao,M.R.
  TITLE     Mapping post-translational modifications of mammalian testicular
            specific histone variant TH2B in tetraploid and haploid germ cells
            and their implications on the dynamics of nucleosome structure
  JOURNAL   J Proteome Res 13 (12), 5603-5617 (2014)
   PUBMED   25252820
  REMARK    GeneRIF: Testis specific histone TH2B undergoes multiple post
            translational amino acid modification, suggesting the possibility
            of chromatin regulation.
REFERENCE   4  (bases 1 to 470)
  AUTHORS   Urahama,T., Horikoshi,N., Osakabe,A., Tachiwana,H. and
            Kurumizaka,H.
  TITLE     Structure of human nucleosome containing the testis-specific
            histone variant TSH2B
  JOURNAL   Acta Crystallogr F Struct Biol Commun 70 (Pt 4), 444-449 (2014)
   PUBMED   24699735
REFERENCE   5  (bases 1 to 470)
  AUTHORS   Shinagawa,T., Takagi,T., Tsukamoto,D., Tomaru,C., Huynh,L.M.,
            Sivaraman,P., Kumarevel,T., Inoue,K., Nakato,R., Katou,Y., Sado,T.,
            Takahashi,S., Ogura,A., Shirahige,K. and Ishii,S.
  TITLE     Histone variants enriched in oocytes enhance reprogramming to
            induced pluripotent stem cells
  JOURNAL   Cell Stem Cell 14 (2), 217-227 (2014)
   PUBMED   24506885
REFERENCE   6  (bases 1 to 470)
  AUTHORS   Golebiowski,F. and Kasprzak,K.S.
  TITLE     Inhibition of core histones acetylation by carcinogenic nickel(II)
  JOURNAL   Mol Cell Biochem 279 (1-2), 133-139 (2005)
   PUBMED   16283522
REFERENCE   7  (bases 1 to 470)
  AUTHORS   Walter,L., Klinga-Levan,K., Helou,K., Albig,W., Drabent,B.,
            Doenecke,D., Gunther,E. and Levan,G.
  TITLE     Chromosome mapping of rat histone genes H1fv, H1d, H1t, Th2a and
            Th2b
  JOURNAL   Cytogenet Cell Genet 75 (2-3), 136-139 (1996)
   PUBMED   9040779
REFERENCE   8  (bases 1 to 470)
  AUTHORS   Huh,N.E., Hwang,I.W., Lim,K., You,K.H. and Chae,C.B.
  TITLE     Presence of a bi-directional S phase-specific transcription
            regulatory element in the promoter shared by testis-specific TH2A
            and TH2B histone genes
  JOURNAL   Nucleic Acids Res 19 (1), 93-98 (1991)
   PUBMED   2011515
REFERENCE   9  (bases 1 to 470)
  AUTHORS   Hwang,I. and Chae,C.B.
  TITLE     S-phase-specific transcription regulatory elements are present in a
            replication-independent testis-specific H2B histone gene
  JOURNAL   Mol Cell Biol 9 (3), 1005-1013 (1989)
   PUBMED   2725487
REFERENCE   10 (bases 1 to 470)
  AUTHORS   Kim,Y.J., Hwang,I., Tres,L.L., Kierszenbaum,A.L. and Chae,C.B.
  TITLE     Molecular cloning and differential expression of somatic and
            testis-specific H2B histone genes during rat spermatogenesis
  JOURNAL   Dev Biol 124 (1), 23-34 (1987)
   PUBMED   3666307
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from M18046.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript is intronless :: M18046.1, M18045.1 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..470
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="Sprague-Dawley"
                     /db_xref="taxon:10116"
                     /chromosome="17"
                     /map="17p11"
     gene            1..470
                     /gene="H2bc1"
                     /gene_synonym="Hist1h2ba; histone; Th2b"
                     /note="H2B clustered histone 1"
                     /db_xref="GeneID:24829"
                     /db_xref="RGD:3855"
     exon            1..470
                     /gene="H2bc1"
                     /gene_synonym="Hist1h2ba; histone; Th2b"
                     /inference="alignment:Splign:2.1.0"
     CDS             42..425
                     /gene="H2bc1"
                     /gene_synonym="Hist1h2ba; histone; Th2b"
                     /note="histone H2B, testis; testis-specific histone H2B;
                     testis-specific histone 2b; histone 1, H2ba; histone
                     cluster 1, H2ba; histone cluster 1 H2B family member a"
                     /codon_start=1
                     /product="histone H2B type 1-A"
                     /protein_id="NP_072169.1"
                     /db_xref="GeneID:24829"
                     /db_xref="RGD:3855"
                     /translation="MPEVSAKGTTISKKGFKKAVTKTQKKEGRKRKRCREESYSIYIY
                     KVLKQVHPDTGISSKAMSIMNSFVTDIFERIAGEASRLAHYNKRSTITSREIQTAVRL
                     LLPGELAKHAVSEGTKAVTKYTSSK"
ORIGIN      
        1 ctgttttgag acgttggagt ggacaaactt atttttccac gatgccggag gtgtcggcaa
       61 aggggactac tatttccaag aaagggttca agaaagcagt caccaagacc cagaagaagg
      121 agggccggaa acgtaagaga tgccgcgaag agagttactc catctacatt tataaggtgc
      181 tgaagcaagt gcacccggac accggcatct cttccaaggc catgagcatc atgaactcct
      241 tcgtgacaga catcttcgag cgcatcgcgg gcgaggcatc gcgcctggcg cattacaaca
      301 agcgctcgac catcacgtcc cgggagatcc agacggctgt ccgcctgctg ctgcccgggg
      361 agctggccaa gcacgctgtg tccgagggca ccaaggcggt caccaagtac accagctcca
      421 agtgagccca cagagctcac aacagaccca aaggctcttt tcagagccac
//
