LOCUS       NM_001106019            1892 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus H2A.Z variant histone 2 (H2az2), mRNA.
ACCESSION   NM_001106019 XM_001069685
VERSION     NM_001106019.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1892)
  AUTHORS   de Mateo,S., Castillo,J., Estanyol,J.M., Ballesca,J.L. and Oliva,R.
  TITLE     Proteomic characterization of the human sperm nucleus
  JOURNAL   Proteomics 11 (13), 2714-2726 (2011)
   PUBMED   21630459
REFERENCE   2  (bases 1 to 1892)
  AUTHORS   Dryhurst,D., Ishibashi,T., Rose,K.L., Eirin-Lopez,J.M.,
            McDonald,D., Silva-Moreno,B., Veldhoen,N., Helbing,C.C.,
            Hendzel,M.J., Shabanowitz,J., Hunt,D.F. and Ausio,J.
  TITLE     Characterization of the histone H2A.Z-1 and H2A.Z-2 isoforms in
            vertebrates
  JOURNAL   BMC Biol 7, 86 (2009)
   PUBMED   20003410
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1892)
  AUTHORS   Sigal,A., Milo,R., Cohen,A., Geva-Zatorsky,N., Klein,Y., Alaluf,I.,
            Swerdlin,N., Perzov,N., Danon,T., Liron,Y., Raveh,T.,
            Carpenter,A.E., Lahav,G. and Alon,U.
  TITLE     Dynamic proteomics in individual human cells uncovers widespread
            cell-cycle dependence of nuclear proteins
  JOURNAL   Nat Methods 3 (7), 525-531 (2006)
   PUBMED   16791210
REFERENCE   4  (bases 1 to 1892)
  AUTHORS   Boyne,M.T. 2nd, Pesavento,J.J., Mizzen,C.A. and Kelleher,N.L.
  TITLE     Precise characterization of human histones in the H2A gene family
            by top down mass spectrometry
  JOURNAL   J Proteome Res 5 (2), 248-253 (2006)
   PUBMED   16457589
REFERENCE   5  (bases 1 to 1892)
  AUTHORS   Florea,L., Di Francesco,V., Miller,J., Turner,R., Yao,A.,
            Harris,M., Walenz,B., Mobarry,C., Merkulov,G.V., Charlab,R.,
            Dew,I., Deng,Z., Istrail,S., Li,P. and Sutton,G.
  TITLE     Gene and alternative splicing annotation with AIR
  JOURNAL   Genome Res 15 (1), 54-66 (2005)
   PUBMED   15632090
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000014.1.
            
            On Nov 4, 2022 this sequence version replaced NM_001106019.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BQ210311.1, SRR26643285.39293.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN16676789, SAMN16676807
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-92                JAXUCZ010000014.1  85525977-85526068   c
            93-170              JAXUCZ010000014.1  85520891-85520968   c
            171-284             JAXUCZ010000014.1  85514289-85514402   c
            285-414             JAXUCZ010000014.1  85509460-85509589   c
            415-1892            JAXUCZ010000014.1  85507228-85508705   c
FEATURES             Location/Qualifiers
     source          1..1892
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="14"
                     /map="14q21"
     gene            1..1892
                     /gene="H2az2"
                     /gene_synonym="H2A.Z-2; H2afv"
                     /note="H2A.Z variant histone 2"
                     /db_xref="GeneID:685909"
                     /db_xref="RGD:1587865"
     exon            1..92
                     /gene="H2az2"
                     /gene_synonym="H2A.Z-2; H2afv"
                     /inference="alignment:Splign:2.1.0"
     CDS             90..476
                     /gene="H2az2"
                     /gene_synonym="H2A.Z-2; H2afv"
                     /note="H2A histone family, member V"
                     /codon_start=1
                     /product="H2A.Z variant histone 2"
                     /protein_id="NP_001099489.1"
                     /db_xref="GeneID:685909"
                     /db_xref="RGD:1587865"
                     /translation="MAGGKAGKDSGKAKAKAVSRSQRAGLQFPVGRIHRHLKTRTTSH
                     GRVGATAAVYSAAILEYLTAEVLELAGNASKDLKVKRITPRHLQLAIRGDEELDSLIK
                     ATIAGGGVIPHIHKSLIGKKGQQKTA"
     exon            93..170
                     /gene="H2az2"
                     /gene_synonym="H2A.Z-2; H2afv"
                     /inference="alignment:Splign:2.1.0"
     exon            171..284
                     /gene="H2az2"
                     /gene_synonym="H2A.Z-2; H2afv"
                     /inference="alignment:Splign:2.1.0"
     exon            285..414
                     /gene="H2az2"
                     /gene_synonym="H2A.Z-2; H2afv"
                     /inference="alignment:Splign:2.1.0"
     exon            415..1892
                     /gene="H2az2"
                     /gene_synonym="H2A.Z-2; H2afv"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gggcattgtc cggctctagc tgcggcggtc cgactgcgag agcagcggcg gcggcgcggg
       61 gctgcagtgg gcgtcgcgcg gccgagacca tggctggagg caaagctgga aaagacagcg
      121 ggaaggccaa ggctaaggca gtgtctcgct cacagagagc tgggctccag tttcctgtgg
      181 gccgcatcca cagacacttg aagactcgca ccacaagcca tggacgggtg ggcgccactg
      241 ctgctgtgta cagtgctgca attctggagt acctcacagc tgaggtgttg gagttggcag
      301 gtaatgcttc taaagatctc aaagtaaagc gcatcacccc acgtcactta cagcttgcaa
      361 tccgaggtga cgaagagttg gattcactga tcaaggctac catagccggg ggcggtgtga
      421 ttccgcacat ccacaagtct ctgatcggaa agaaggggca gcagaaaact gcttaggacg
      481 tgagtcactg acctgctgtc ctcactgtgt gtgactgggc agagggtacc agtcggtgtg
      541 tgggaaagca tagacaattg ctgtagacag aagacacatt tgtatgtttt tagactctcg
      601 aagtttgata aactcctttc cctgtggtca gtcatgtgtt gactggccag gtctctccct
      661 tgtgttttat acaaaaatag aattgataaa cattttttac aaaaggaatt tgtctcagta
      721 tttcttcatg atgtgttaga aatacttttt tttttttttg acactccgtc agtaaattaa
      781 acgcttaaag tacgcagatc cacccccaga ttgcgattta agactgtttc ctgcatggtt
      841 tgtctcctca gtcacggtcc acaggactct gagaagtcgt aggaatatgc aggcgcagac
      901 tcgaagcccc gcttcatctc caatgttgtg gaaagggact gtacatcatc gggcagtacc
      961 ctatgctccc gtgtgttaga aatactttgt tttacctggg catggccgtg ttgcttgcga
     1021 ccccagcatt tgggaggagt gggcaggacc ttcagagttg gtgctgatct ttgcctacac
     1081 tccaagttct ttgacaacct agactacaag agactctgtc tcaaaagaaa aaacattgtt
     1141 tgttcagaca ttgacatttt aagttgcaaa ttagttattc agaattatct tgaggcaaaa
     1201 attaggatgt aatgtacctt gattggtata gtttttgttt gaatctcgga tataatcaat
     1261 ttttagaaat atgtatttat taatgtatac agtgttctgc ctccatgtat gcctgcaggc
     1321 cataagaagg aacaaggtct cttaacagat ggttgtgagc caccatgtgg ttgctgggaa
     1381 ttgaactcag gacctctgga agagcagtca gtgctcttaa ctgctgagcc atctctccgg
     1441 tcctcatcaa ggagtgttac tacccctctt tatgggcatg tgcgcccatt gtccacagga
     1501 attaatgatc tgctgagaag acagtcgagc tggcagaaac gacagtggag tcaggacaca
     1561 aacctgggtc tttctggctt cagagtgccc cctgacctag aaatgatact actgagttag
     1621 acttttctga ttgggtcctg gaattctaac tttgtggtca ctcactgatc ccactaacct
     1681 gcagtaactg tataaagatg atgtctacgt gactgcaaga tgtaagttaa ttcactagta
     1741 aatgtgacag ccaaaatttt atttttcatc aatgtctttg tgagaaattg atattttata
     1801 acataacagt atcaaaacag ttcatttttg aagaaatatt ttattatggg aattctgaca
     1861 agtgcacaga aataaagaga atagcactag cg
//
