LOCUS       NM_012579                745 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus H1.6 linker histone, cluster member (H1f6), mRNA.
ACCESSION   NM_012579
VERSION     NM_012579.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 745)
  AUTHORS   de Mateo,S., Castillo,J., Estanyol,J.M., Ballesca,J.L. and Oliva,R.
  TITLE     Proteomic characterization of the human sperm nucleus
  JOURNAL   Proteomics 11 (13), 2714-2726 (2011)
   PUBMED   21630459
REFERENCE   2  (bases 1 to 745)
  AUTHORS   Sarg,B., Chwatal,S., Talasz,H. and Lindner,H.H.
  TITLE     Testis-specific linker histone H1t is multiply phosphorylated
            during spermatogenesis. Identification of phosphorylation sites
  JOURNAL   J Biol Chem 284 (6), 3610-3618 (2009)
   PUBMED   19043117
  REMARK    GeneRIF: it appears that not the order of up-phosphorylation but
            the number of the phosphate groups is necessary for regulated
            chromatin decondensation, thus facilitating the substitution of H1t
            by transition proteins and protamines.
REFERENCE   3  (bases 1 to 745)
  AUTHORS   VanWert,J.M., Wolfe,S.A. and Grimes,S.R.
  TITLE     Binding of RFX2 and NF-Y to the testis-specific histone H1t
            promoter may be required for transcriptional activation in primary
            spermatocytes
  JOURNAL   J Cell Biochem 104 (3), 1087-1101 (2008)
   PUBMED   18247329
  REMARK    GeneRIF: RFX2 and NF-Y binding to the testis-specific histone H1t
            promoter may be required for transcriptional activation in primary
            spermatocytes
REFERENCE   4  (bases 1 to 745)
  AUTHORS   Yang,F., Gell,K., van der Heijden,G.W., Eckardt,S., Leu,N.A.,
            Page,D.C., Benavente,R., Her,C., Hoog,C., McLaughlin,K.J. and
            Wang,P.J.
  TITLE     Meiotic failure in male mice lacking an X-linked factor
  JOURNAL   Genes Dev 22 (5), 682-691 (2008)
   PUBMED   18316482
REFERENCE   5  (bases 1 to 745)
  AUTHORS   Yang,F., Eckardt,S., Leu,N.A., McLaughlin,K.J. and Wang,P.J.
  TITLE     Mouse TEX15 is essential for DNA double-strand break repair and
            chromosomal synapsis during male meiosis
  JOURNAL   J Cell Biol 180 (4), 673-679 (2008)
   PUBMED   18283110
REFERENCE   6  (bases 1 to 745)
  AUTHORS   Walter,L., Klinga-Levan,K., Helou,K., Albig,W., Drabent,B.,
            Doenecke,D., Gunther,E. and Levan,G.
  TITLE     Chromosome mapping of rat histone genes H1fv, H1d, H1t, Th2a and
            Th2b
  JOURNAL   Cytogenet Cell Genet 75 (2-3), 136-139 (1996)
   PUBMED   9040779
REFERENCE   7  (bases 1 to 745)
  AUTHORS   Wolfe,S.A. and Grimes,S.R.
  TITLE     Protein-DNA interactions within the rat histone H4t promoter
  JOURNAL   J Biol Chem 266 (10), 6637-6643 (1991)
   PUBMED   1706721
REFERENCE   8  (bases 1 to 745)
  AUTHORS   Lindner,H., Helliger,W. and Puschendorf,B.
  TITLE     Separation of rat tissue histone H1 subtypes by reverse-phase
            h.p.l.c. Identification and assignment to a standard H1
            nomenclature
  JOURNAL   Biochem J 269 (2), 359-363 (1990)
   PUBMED   2386482
  REMARK    Erratum:[Biochem J 1990 Nov 1;271(3):842]
REFERENCE   9  (bases 1 to 745)
  AUTHORS   Cole,K.D., Kandala,J.C. and Kistler,W.S.
  TITLE     Isolation of the gene for the testis-specific H1 histone variant
            H1t
  JOURNAL   J Biol Chem 261 (16), 7178-7183 (1986)
   PUBMED   2423516
REFERENCE   10 (bases 1 to 745)
  AUTHORS   Cole,K.D., York,R.G. and Kistler,W.S.
  TITLE     Sequence of the amino terminal half of rat testis-specific histone
            variant H1t
  JOURNAL   Biochim Biophys Acta 869 (3), 223-229 (1986)
   PUBMED   3947637
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from M13170.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..745
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="17"
                     /map="17p11"
     gene            1..745
                     /gene="H1f6"
                     /gene_synonym="H1-6; H1.3; H1D; H1f3; H1ft; H1s-4; H1t;
                     Hist1h1t"
                     /note="H1.6 linker histone, cluster member"
                     /db_xref="GeneID:24438"
                     /db_xref="RGD:2778"
     exon            1..745
                     /gene="H1f6"
                     /gene_synonym="H1-6; H1.3; H1D; H1f3; H1ft; H1s-4; H1t;
                     Hist1h1t"
                     /inference="alignment:Splign:2.1.0"
     CDS             70..696
                     /gene="H1f6"
                     /gene_synonym="H1-6; H1.3; H1D; H1f3; H1ft; H1s-4; H1t;
                     Hist1h1t"
                     /note="histone 1, H1t; histone 1, family 3; H1 histone
                     family, member 3; H1 histone family, member T
                     (testis-specific); testis-specific histone 1, probably
                     same as Hh1tts; histone 1t; histone 1 a family 3; histone
                     cluster 1 H1 family member t; histone cluster 1, H1t"
                     /codon_start=1
                     /product="histone H1t"
                     /protein_id="NP_036711.1"
                     /db_xref="GeneID:24438"
                     /db_xref="RGD:2778"
                     /translation="MSETAPAASSTLVPAPVEKPATKRRGKKPGMATARKPRGFSVSK
                     LIPEALSMSQERAGMSLAALKKALAAAGYDVEKNNSRIKLALKRLVNKGVLVQTKGTG
                     ASGSFKLSKKAASGNDKGKGKKSASAKAKKLGLSRASRSPKSSKTKVVKKPKATPTKG
                     SGSRRKTKGAKGLQQRKSPAKARATNSNSGKSKMVMQKTDLRKAAGRK"
ORIGIN      
        1 actccagcgc tgttcgctct cctgtacttt tttttttaat tgggtgtagt tcttgaccag
       61 ctcttgacta tgtcggaaac ggctcctgca gcctcaagta ctcttgttcc agctcctgta
      121 gagaaacctg caactaaaag gcgagggaag aagcctggca tggccactgc tcgcaaacct
      181 cggggtttct cggtttccaa gttgattcct gaggcccttt ccatgtctca ggaacgggca
      241 ggaatgtccc ttgctgccct gaagaaagcc ctggctgcgg ctggctatga cgtggagaag
      301 aacaacagtc gtatcaagct ggccctcaag agacttgtga ataagggagt cctggtgcag
      361 accaagggca ccggagcctc aggctccttc aagcttagca agaaggcagc ttcaggcaac
      421 gacaagggca agggcaagaa atctgcttct gccaaggcta agaaactggg cttgtccagg
      481 gcctcgagat cccccaagag tagtaagacc aaggttgtca agaagccaaa agctacgccc
      541 acaaagggtt ctgggagcag aaggaagacc aaaggggcca agggcttgca acagcgcaaa
      601 agccccgcca aagcgagggc aaccaactcc aactctggga agtcaaagat ggtcatgcag
      661 aagaccgacc taaggaaggc agcaggaaga aagtgagttt caaagccagt tttcaaaaac
      721 ccaaaggctc ttttaagagc cactt
//
