LOCUS       NM_017119                882 bp    mRNA    linear   ROD 01-JUN-2024
DEFINITION  Rattus norvegicus granzyme K (Gzmk), mRNA.
ACCESSION   NM_017119
VERSION     NM_017119.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 882)
  AUTHORS   Sayers,T.J., Wiltrout,T.A., Smyth,M.J., Ottaway,K.S., Pilaro,A.M.,
            Sowder,R., Henderson,L.E., Sprenger,H. and Lloyd,A.R.
  TITLE     Purification and cloning of a novel serine protease, RNK-Tryp-2,
            from the granules of a rat NK cell leukemia
  JOURNAL   J Immunol 152 (5), 2289-2297 (1994)
   PUBMED   8133042
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from L19694.1.
            
            On Feb 21, 2013 this sequence version replaced NM_017119.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: L19694.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760386 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-882               L19694.1           1-882
FEATURES             Location/Qualifiers
     source          1..882
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="F344"
                     /db_xref="taxon:10116"
                     /chromosome="2"
                     /map="2q14"
     gene            1..882
                     /gene="Gzmk"
                     /note="granzyme K"
                     /db_xref="GeneID:29165"
                     /db_xref="RGD:68401"
     exon            1..85
                     /gene="Gzmk"
                     /inference="alignment:Splign:2.1.0"
     CDS             25..801
                     /gene="Gzmk"
                     /EC_number="3.4.21.-"
                     /note="NK-Tryp-2; NK-tryptase-2; RNK-Tryp-2"
                     /codon_start=1
                     /product="granzyme K precursor"
                     /protein_id="NP_058815.1"
                     /db_xref="GeneID:29165"
                     /db_xref="RGD:68401"
                     /translation="MSFSSSALVFLVAGIYMSSESFHTEIIGGREVQPHSRPFMASIQ
                     YRGKHICGGVLIHPQWVLTAAHCYSRGHSPTVVLGAHSLSKNEPMKQTFEIKEFIPFS
                     GFKSGTNDIMLIKLRTAAELNKHVQLLHLRSKNYIRDGTKCQVTGWGSTKPDVLTTSD
                     TLQEVTVTIISRKRCNSQSYYNHKPVITKDMICAGDRRGEKDSCKGDSGGPLICKGVF
                     HALVSGGYKCGISNKPGVYTLLTKKYQTWIKSKLAPSSAH"
     exon            86..233
                     /gene="Gzmk"
                     /inference="alignment:Splign:2.1.0"
     exon            234..369
                     /gene="Gzmk"
                     /inference="alignment:Splign:2.1.0"
     exon            370..639
                     /gene="Gzmk"
                     /inference="alignment:Splign:2.1.0"
     exon            640..882
                     /gene="Gzmk"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cctcgacacc gaggccctgt aattatgagc ttttcttcat ctgctctggt tttccttgtg
       61 gccgggattt atatgtcttc agagagtttc catactgaaa ttattggagg gagagaagta
      121 cagccacatt ccaggccttt tatggcttcc atccagtacc gcggcaagca tatttgtgga
      181 ggagtcctga tccatccgca gtgggtgcta acagccgccc actgctactc tcgaggccac
      241 tctcccacgg ttgttttagg agcacattct ctttcaaaga atgagcccat gaaacagaca
      301 tttgagatta aggaattcat cccgttctca ggatttaagt ctggaacgaa tgacatcatg
      361 ctgataaagc ttcgcacggc tgcagaactg aacaagcatg tccaactgct tcacctgaga
      421 tccaaaaact atattagaga tggaactaaa tgccaggtta ctggctgggg atccaccaag
      481 ccagatgtgt taaccacctc tgatacactg caggaagtca ctgttaccat cataagtaga
      541 aaacgctgca acagccagag ctactacaac cataaacctg ttataaccaa ggacatgatc
      601 tgtgcagggg atcgcagagg cgaaaaggat tcctgcaagg gtgactctgg tggtcctttg
      661 atctgcaaag gtgtcttcca tgccctagtc tctgggggct ataaatgtgg catctccaac
      721 aagcctggag tctacaccct gttgactaag aaatatcaga cctggatcaa aagcaagctt
      781 gccccgtcga gtgcacattg agatgacaag tggttttctt ggatctgcca gtcacttgct
      841 tctttttcca ggacaagctt gcagactggc tttctcttcg gg
//
