LOCUS       NM_153466                872 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus granzyme F (Gzmf), mRNA.
ACCESSION   NM_153466
VERSION     NM_153466.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 872)
  AUTHORS   Ewoldt,G.R., Smyth,M.J., Darcy,P.K., Harris,J.L., Craik,C.S.,
            Horowitz,B., Woodard,S.L., Powers,J.C. and Hudig,D.
  TITLE     P-4 and RNKP-7, new granzyme-like serine proteases expressed in
            activated rat lymphocytes
  JOURNAL   J Immunol 158 (10), 4574-4583 (1997)
   PUBMED   9144469
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000015.1.
            
            On Mar 18, 2021 this sequence version replaced NM_153466.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: U57063.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-62                JAXUCZ010000015.1  33988826-33988887   c
            63-213              JAXUCZ010000015.1  33979717-33979867   c
            214-349             JAXUCZ010000015.1  33978609-33978744   c
            350-610             JAXUCZ010000015.1  33978147-33978407   c
            611-872             JAXUCZ010000015.1  33977505-33977766   c
FEATURES             Location/Qualifiers
     source          1..872
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="15"
                     /map="15p12"
     gene            1..872
                     /gene="Gzmf"
                     /gene_synonym="Gzmg; Rnkp7"
                     /note="granzyme F"
                     /db_xref="GeneID:266704"
                     /db_xref="RGD:628603"
     exon            1..62
                     /gene="Gzmf"
                     /gene_synonym="Gzmg; Rnkp7"
                     /inference="alignment:Splign:2.1.0"
     CDS             8..754
                     /gene="Gzmf"
                     /gene_synonym="Gzmg; Rnkp7"
                     /note="granzyme G; natural killer cell protease 7;
                     granzyme H; granzyme G-like"
                     /codon_start=1
                     /product="granzyme H precursor"
                     /protein_id="NP_703196.2"
                     /db_xref="GeneID:266704"
                     /db_xref="RGD:628603"
                     /translation="MLPVLILMTILLPLEAGAEEIIGGHEVKPHSRPYMAHVKFVKVD
                     GNRSVCGGFLVQDYFVLTAAHCTGRSMKVILGAHNLHVQEKTQQIIPVKRAIPHPAYN
                     REDHINDIMLLKLESKAKKTRAVRPLNLPRPNDMVKPGDVCRVAGWGQMSVDVTKRTS
                     RLQEAKLIIQEDKECKKLFHHYSETTEICAGDPKKIQAAYKGDSGGPLVCENRAYGVV
                     SYGKNGTISSGVFTKVVYFLPWISRNMKLL"
     exon            63..213
                     /gene="Gzmf"
                     /gene_synonym="Gzmg; Rnkp7"
                     /inference="alignment:Splign:2.1.0"
     exon            214..349
                     /gene="Gzmf"
                     /gene_synonym="Gzmg; Rnkp7"
                     /inference="alignment:Splign:2.1.0"
     exon            350..610
                     /gene="Gzmf"
                     /gene_synonym="Gzmg; Rnkp7"
                     /inference="alignment:Splign:2.1.0"
     exon            611..872
                     /gene="Gzmf"
                     /gene_synonym="Gzmg; Rnkp7"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tgggaagatg ctaccagttc tcattctcat gaccatactt ctgcctcttg aagctggagc
       61 agaggagatt atcgggggcc atgaggtcaa gccccactcc cgcccttaca tggcacatgt
      121 gaaatttgtg aaagttgatg ggaatagaag tgtctgcgga ggcttcctgg ttcaagacta
      181 ctttgtgctg acggctgctc actgcactgg aagatcaatg aaagtcatac taggggccca
      241 caatctccat gtgcaggaga agactcagca gatcatccct gtgaaaaggg ctattcctca
      301 cccggcctat aatcgtgagg accacattaa tgacatcatg ctattaaagt tggagagtaa
      361 ggccaagaag actagagctg tgaggcctct caatttgccc aggcccaatg acatggtgaa
      421 gccaggggat gtgtgtcgtg ttgctggctg gggccaaatg tccgtcgatg tcactaaaag
      481 aacttcccgc ctacaagagg ctaaactgat catccaggag gacaaggaat gcaaaaaact
      541 cttccatcac tactctgaga ccacggagat ttgtgctgga gacccaaaga aaatacaggc
      601 tgcgtacaag ggtgactctg ggggacccct tgtgtgtgaa aacagagctt atggagttgt
      661 atcctatggg aaaaatggga caatctcttc aggagtcttc accaaggttg tgtacttcct
      721 gccatggata agcagaaaca tgaagctcct ctaacaggtt aacacctgtg cccaaccagc
      781 ctttctgacc tcaggcaaga accacgatga gtgtgcgtca aaggctgaaa atccgtaata
      841 aataaccccc agtgtgcatg taatttaagt ac
//
