LOCUS       NM_031043               1621 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus glycogenin 1 (Gyg1), mRNA.
ACCESSION   NM_031043
VERSION     NM_031043.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1621)
  AUTHORS   Bilyard,M.K., Bailey,H.J., Raich,L., Gafitescu,M.A., Machida,T.,
            Iglesias-Fernandez,J., Lee,S.S., Spicer,C.D., Rovira,C., Yue,W.W.
            and Davis,B.G.
  TITLE     Palladium-mediated enzyme activation suggests multiphase initiation
            of glycogenesis
  JOURNAL   Nature 563 (7730), 235-240 (2018)
   PUBMED   30356213
REFERENCE   2  (bases 1 to 1621)
  AUTHORS   Chaikuad,A., Froese,D.S., Berridge,G., von Delft,F., Oppermann,U.
            and Yue,W.W.
  TITLE     Conformational plasticity of glycogenin and its maltosaccharide
            substrate during glycogen biogenesis
  JOURNAL   Proc Natl Acad Sci U S A 108 (52), 21028-21033 (2011)
   PUBMED   22160680
REFERENCE   3  (bases 1 to 1621)
  AUTHORS   Moslemi,A.R., Lindberg,C., Nilsson,J., Tajsharghi,H., Andersson,B.
            and Oldfors,A.
  TITLE     Glycogenin-1 deficiency and inactivated priming of glycogen
            synthesis
  JOURNAL   N Engl J Med 362 (13), 1203-1210 (2010)
   PUBMED   20357282
REFERENCE   4  (bases 1 to 1621)
  AUTHORS   Ghosh,D., Lippert,D., Krokhin,O., Cortens,J.P. and Wilkins,J.A.
  TITLE     Defining the membrane proteome of NK cells
  JOURNAL   J Mass Spectrom 45 (1), 1-25 (2010)
   PUBMED   19946888
REFERENCE   5  (bases 1 to 1621)
  AUTHORS   Hansen,B.F., Derave,W., Jensen,P. and Richter,E.A.
  TITLE     No limiting role for glycogenin in determining maximal attainable
            glycogen levels in rat skeletal muscle
  JOURNAL   Am J Physiol Endocrinol Metab 278 (3), E398-E404 (2000)
   PUBMED   10710493
REFERENCE   6  (bases 1 to 1621)
  AUTHORS   Pak,B.J., Sangaralingham,S.J. and Pang,S.C.
  TITLE     Molecular cloning and developmental expression of rat glycogenin in
            cardiac tissue
  JOURNAL   Mol Cell Biochem 194 (1-2), 117-123 (1999)
   PUBMED   10391131
REFERENCE   7  (bases 1 to 1621)
  AUTHORS   Barbetti,F., Rocchi,M., Bossolasco,M., Cordera,R., Sbraccia,P.,
            Finelli,P. and Consalez,G.G.
  TITLE     The human skeletal muscle glycogenin gene: cDNA, tissue expression
            and chromosomal localization
  JOURNAL   Biochem Biophys Res Commun 220 (1), 72-77 (1996)
   PUBMED   8602861
REFERENCE   8  (bases 1 to 1621)
  AUTHORS   Lomako,J., Lomako,W.M., Whelan,W.J., Dombro,R.S., Neary,J.T. and
            Norenberg,M.D.
  TITLE     Glycogen synthesis in the astrocyte: from glycogenin to proglycogen
            to glycogen
  JOURNAL   FASEB J 7 (14), 1386-1393 (1993)
   PUBMED   8224611
REFERENCE   9  (bases 1 to 1621)
  AUTHORS   Viskupic,E., Cao,Y., Zhang,W., Cheng,C., DePaoli-Roach,A.A. and
            Roach,P.J.
  TITLE     Rabbit skeletal muscle glycogenin. Molecular cloning and production
            of fully functional protein in Escherichia coli
  JOURNAL   J Biol Chem 267 (36), 25759-25763 (1992)
   PUBMED   1281472
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AF021343.1.
            
            On Aug 31, 2012 this sequence version replaced NM_031043.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AF021343.1, BC070944.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN12840115, SAMN16093046
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1621              AF021343.1         4-1624
FEATURES             Location/Qualifiers
     source          1..1621
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="W"
                     /db_xref="taxon:10116"
                     /chromosome="2"
                     /map="2q24"
     gene            1..1621
                     /gene="Gyg1"
                     /gene_synonym="Gyg"
                     /note="glycogenin 1"
                     /db_xref="GeneID:81675"
                     /db_xref="RGD:621785"
     exon            1..11
                     /gene="Gyg1"
                     /gene_synonym="Gyg"
                     /inference="alignment:Splign:2.1.0"
     CDS             5..1006
                     /gene="Gyg1"
                     /gene_synonym="Gyg"
                     /EC_number="2.4.1.186"
                     /note="GN1; GN-1"
                     /codon_start=1
                     /product="glycogenin-1"
                     /protein_id="NP_112305.1"
                     /db_xref="GeneID:81675"
                     /db_xref="RGD:621785"
                     /translation="MTDQAFVTLTTNDAYAKGALVLGSSLKQHRTTRRTVVLASPQVS
                     DSMRKVLETVFDEVIMVDVLDSGDSAHLTLMKRPELGITLTKLHCWSLTQYSKCVFMD
                     ADTLVLSNIDDLFEREELSAAPDPGWPDCFNSGVFVYQPSIETYNQLLHLASEQGSFD
                     GGDQGLLNTYFSGWATTDITKHLPFVYNLSSLSIYSYLPAFKAFGKNAKVVHFLGRTK
                     PWNYTYNPQTKSVKCESQDPIVSHPEFLNLWWDTFTTNVLPLLQHHGLVKDAGSYLMM
                     EHVTGALSDLSFGEAPPASQPSLSSEERKERWEQGQADYMGADSFDNIKRKLDTYLQ"
     exon            12..147
                     /gene="Gyg1"
                     /gene_synonym="Gyg"
                     /inference="alignment:Splign:2.1.0"
     exon            148..322
                     /gene="Gyg1"
                     /gene_synonym="Gyg"
                     /inference="alignment:Splign:2.1.0"
     exon            323..485
                     /gene="Gyg1"
                     /gene_synonym="Gyg"
                     /inference="alignment:Splign:2.1.0"
     exon            486..612
                     /gene="Gyg1"
                     /gene_synonym="Gyg"
                     /inference="alignment:Splign:2.1.0"
     exon            613..832
                     /gene="Gyg1"
                     /gene_synonym="Gyg"
                     /inference="alignment:Splign:2.1.0"
     exon            833..1612
                     /gene="Gyg1"
                     /gene_synonym="Gyg"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 caccatgaca gatcaggctt ttgtgacgct caccacaaac gatgcctatg ccaaaggggc
       61 gctggtcctg ggctcatctt tgaaacagca caggactact aggaggacgg ttgtactcgc
      121 cagcccacag gtttcagact ccatgagaaa agttttagag actgtctttg atgaagtcat
      181 catggtagat gtcttggaca gtggtgattc tgctcatcta accttaatga agaggcctga
      241 gttgggcatc acgttgacta aactccactg ctggtcactc actcagtatt ccaaatgtgt
      301 gttcatggat gcagatactc tggttctctc aaatattgat gatctttttg aaagagaaga
      361 attgtcagca gcaccagacc cagggtggcc tgactgtttc aattctggag tctttgtcta
      421 tcaaccctca attgaaacgt ataaccagct gttgcatctt gcttctgagc aaggtagttt
      481 tgatggtggg gaccagggcc tactgaatac atattttagt ggctgggcaa cgacagatat
      541 cacaaaacac ttgccatttg tgtataacct gagcagcctc tcaatatact cctacctccc
      601 ggcatttaaa gcgtttggta aaaatgccaa agttgtgcac ttcctgggac gaaccaagcc
      661 atggaattac acgtacaatc cccaaacaaa aagtgtcaaa tgtgaatccc aggacccaat
      721 tgtgagtcac ccagagtttc tgaacctgtg gtgggacacc ttcaccacca atgtcttacc
      781 cctgctccaa caccatggcc ttgtcaaaga tgccggttcc tatctaatga tggaacatgt
      841 cacaggagcc ttgtcagacc tgtcctttgg ggaggcccca cctgcatcac agccttcttt
      901 gtcctcagaa gaaaggaagg aacggtggga acagggccag gctgattata tgggagcaga
      961 ttcttttgat aacatcaaga gaaaacttga cacttaccta cagtagaagc actgccattt
     1021 tcttgtggac acatccatgt cttaggcacg tttcgataca tagtatgtga agtctgttac
     1081 aattgttaga ggctttcact aaacctcagc agatgagggg tttgggcagg acaacaggtg
     1141 agaactgggc aaatgttatt aagtaataat tctattatgt ggacaagtgt tgtgtttaac
     1201 cctagacttt ttcaaaaact ctaaattctt aaattgccaa tgtgtgataa agaaaagcca
     1261 acattgagct actaaattag gctctttcaa atggtgcaga acttgactct ccatcttcaa
     1321 aacaaggtat gagattctcc aatatttgct tgttgtatcc ttcactagac ctgcaatgta
     1381 gaattgttca aagcctgtca gagaagtagc cttctagact aaagtggcct ttattaacac
     1441 tgcggagtga ttcataagcc taccagctag tgttagttca ccagttttct atgcaccatg
     1501 aaggcggcat gcagacctgc tctttctcag ttatctactt gaaaattgca gtgtgctctc
     1561 tgatggtagc tgtggaagca ctgtgtataa caaataaaga cttattgaca taaaaaaaaa
     1621 a
//
