LOCUS       NM_001100887            6718 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus glucoside xylosyltransferase 1 (Gxylt1), mRNA.
ACCESSION   NM_001100887 XM_001057023 XM_001057074 XM_217027
VERSION     NM_001100887.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 6718)
  AUTHORS   Pandey,A., Li-Kroeger,D., Sethi,M.K., Lee,T.V., Buettner,F.F.,
            Bakker,H. and Jafar-Nejad,H.
  TITLE     Sensitized genetic backgrounds reveal differential roles for EGF
            repeat xylosyltransferases in Drosophila Notch signaling
  JOURNAL   Glycobiology 28 (11), 849-859 (2018)
   PUBMED   30169771
REFERENCE   2  (bases 1 to 6718)
  AUTHORS   Sethi,M.K., Buettner,F.F., Krylov,V.B., Takeuchi,H.,
            Nifantiev,N.E., Haltiwanger,R.S., Gerardy-Schahn,R. and Bakker,H.
  TITLE     Identification of glycosyltransferase 8 family members as
            xylosyltransferases acting on O-glucosylated notch epidermal growth
            factor repeats
  JOURNAL   J Biol Chem 285 (3), 1582-1586 (2010)
   PUBMED   19940119
REFERENCE   3  (bases 1 to 6718)
  AUTHORS   Iwanaga,R., Komori,H., Ishida,S., Okamura,N., Nakayama,K.,
            Nakayama,K.I. and Ohtani,K.
  TITLE     Identification of novel E2F1 target genes regulated in cell
            cycle-dependent and independent manners
  JOURNAL   Oncogene 25 (12), 1786-1798 (2006)
   PUBMED   16288221
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000007.1.
            
            On or before Nov 22, 2008 this sequence version replaced
            XM_001057074.1, XM_001057023.1, XM_217027.4.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR21887620.1139472.1,
                                           SRR26643288.32042.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760386 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-255               JAXUCZ010000007.1  126313833-126314087 c
            256-348             JAXUCZ010000007.1  126305212-126305304 c
            349-520             JAXUCZ010000007.1  126300630-126300801 c
            521-646             JAXUCZ010000007.1  126298965-126299090 c
            647-898             JAXUCZ010000007.1  126293486-126293737 c
            899-1022            JAXUCZ010000007.1  126288813-126288936 c
            1023-1195           JAXUCZ010000007.1  126288325-126288497 c
            1196-6718           JAXUCZ010000007.1  126280349-126285871 c
FEATURES             Location/Qualifiers
     source          1..6718
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="7"
                     /map="7q35"
     gene            1..6718
                     /gene="Gxylt1"
                     /gene_synonym="Glt8d3"
                     /note="glucoside xylosyltransferase 1"
                     /db_xref="GeneID:300173"
                     /db_xref="RGD:1563062"
     exon            1..255
                     /gene="Gxylt1"
                     /gene_synonym="Glt8d3"
                     /inference="alignment:Splign:2.1.0"
     CDS             50..1357
                     /gene="Gxylt1"
                     /gene_synonym="Glt8d3"
                     /EC_number="2.4.2.42"
                     /note="glycosyltransferase 8 domain-containing protein 3;
                     S33-D; glycosyltransferase 8 domain containing 3"
                     /codon_start=1
                     /product="glucoside xylosyltransferase 1"
                     /protein_id="NP_001094357.1"
                     /db_xref="GeneID:300173"
                     /db_xref="RGD:1563062"
                     /translation="MRRYLRVVGLCLACGFCSLLYAFSQLAVSLEEGAAVGRRPQAAV
                     ASWLADGGRGTGRGAGSAGPGRTGRCKEVSLSYWNPYWMLPSDVCGVNCFWEAAFRYG
                     LKTRPTEKMHLAVVACGDRLEETVTMLKSALIFSIKPLHVHIFAEDQLHDSFKDRLDS
                     WSFLQRFNYSLYPITFPSDSAMEWKKLFKPCASQRLFLPLILKGVDSLLYVDTDVLFL
                     RPVDDIWSLLERFNSTQIAAMAPEHEEPRVGWYNRFARHPYYGRTGVNSGVMLMNMTR
                     MRRKYFKNDMTTARLQWGDILMPLLKKYKLNITWGDQDLLNIMFYHNPESLFVFPCQW
                     NYRPDHCIYGSNCREAEEEGVFILHGNRGVYHDDKQPAFRAMYEALRNCSLEDDSVRS
                     LLKPLELELQKTVHTYCGKTYKIFIKQLAKSIRNRYDTPPKER"
     exon            256..348
                     /gene="Gxylt1"
                     /gene_synonym="Glt8d3"
                     /inference="alignment:Splign:2.1.0"
     exon            349..520
                     /gene="Gxylt1"
                     /gene_synonym="Glt8d3"
                     /inference="alignment:Splign:2.1.0"
     exon            521..646
                     /gene="Gxylt1"
                     /gene_synonym="Glt8d3"
                     /inference="alignment:Splign:2.1.0"
     exon            647..898
                     /gene="Gxylt1"
                     /gene_synonym="Glt8d3"
                     /inference="alignment:Splign:2.1.0"
     exon            899..1022
                     /gene="Gxylt1"
                     /gene_synonym="Glt8d3"
                     /inference="alignment:Splign:2.1.0"
     exon            1023..1195
                     /gene="Gxylt1"
                     /gene_synonym="Glt8d3"
                     /inference="alignment:Splign:2.1.0"
     exon            1196..6718
                     /gene="Gxylt1"
                     /gene_synonym="Glt8d3"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggcggcggcg gtgagggcgg cagcggcggt ggcggtagcg cgggccggga tgcggcgcta
       61 cctgcgggtc gtagggctgt gcctggcctg cggcttctgc tcgctgctgt acgccttcag
      121 ccagctcgca gtgtccttgg aggaaggagc ggccgtaggc cgcaggccgc aggccgcggt
      181 ggcttcctgg ctggcggacg gcggacgcgg caccgggaga ggcgcgggca gcgcgggccc
      241 gggccggacc ggcaggtgta aggaggtctc tctgtcttac tggaatccct actggatgct
      301 gccctctgat gtttgtggag tgaactgctt ttgggaagcg gcttttaggt atggtctgaa
      361 aacaaggccc actgagaaaa tgcaccttgc cgttgtcgcc tgtggtgaca gactggaaga
      421 aactgtgacc atgctgaagt cggctctgat tttcagcatc aagccactgc acgtccacat
      481 ttttgctgaa gaccaactac acgatagctt taaagacaga ctcgacagct ggtcatttct
      541 acagagattc aactatagcc tgtatcccat caccttccca agcgacagtg ccatggagtg
      601 gaagaagctc ttcaagccct gtgcttccca gaggctgttc ttgccattga tactgaaagg
      661 ggttgactcg ctgttgtacg tcgacacgga tgtcctcttc ctgcgacctg ttgatgacat
      721 ctggtcgctg ctggagagat tcaactccac acaaatcgcc gccatggcgc cggagcacga
      781 ggagcccagg gtcggatggt acaaccgctt cgcccggcac ccgtactacg ggcgcacagg
      841 cgtgaactcg ggagtgatgc tcatgaacat gacccggatg aggagaaagt acttcaagaa
      901 cgatatgacc actgcacggc tacaatgggg agacatactt atgccactgc ttaaaaagta
      961 caaactgaac atcacatggg gtgaccaaga tctgctaaat atcatgtttt atcataatcc
     1021 agaaagcctt tttgtcttcc cgtgtcagtg gaattaccgg ccagatcact gtatatatgg
     1081 aagcaattgc cgagaagcag aagaggaagg agtcttcatt cttcatggaa acagaggggt
     1141 ttaccatgac gacaagcagc cagctttcag agctatgtat gaagcactaa gaaattgttc
     1201 tcttgaggat gattccgtcc gttccttact caaaccttta gaactggaac tacagaagac
     1261 agttcacacg tattgtggaa aaacttacaa aatatttatc aagcagttgg cgaaaagcat
     1321 aagaaaccgt tacgacacac caccaaagga aaggtgattc ttcatgacga agtacactga
     1381 agaaacagta atgcctcagg agatatgaag gaatggtatt ggaaaaggat ttagggggcg
     1441 tttctgtctc cagaataatc ctcttcggaa gaattaaatg agcagtatat tcatgccatg
     1501 aagaataagt taaactctgg tgctgcagta agaagatggt ttgtaacatt acttggtgtc
     1561 tttccagcat tagtgaacgc attggacagt gtgggctgtg gggctgggtt ggctcgtgat
     1621 caagtaagta aggactggga ggatggggag aaagtgtacc tcggacatag tggagacatt
     1681 caagctgtga gtgtagcaat aatttatgtc agcactaacc tcactttaag tgtgagaaaa
     1741 gtttacagga gcagaaaggt tctgtttctt aagaaatgtg atgtaaccaa tgttaactgt
     1801 tgacaatcta tgtaccacat acatttcatc tctgctctat gacatttggt gacaatcatg
     1861 tttgagatta tttgtagatt ttacgtaagc tgcacattta aaaattagct gtatgaggaa
     1921 ggagaaaata gtaaaactta aaaggaggca gtgtgtgtgt gccagtgtgt gagtgtgagt
     1981 gagagtgtgt gagtgtgtat gtatgtgagt atgtgtgtgt gagtgtggtg ggtgtgtatg
     2041 tatgtgtgtg tgtgtgtatg agtgtggtgt gtgtatatgt atgtgtgtgt ttgtgcgtgt
     2101 gtgagtgtgg tgtgtgtata tgtatgtgtg tgtgtatgag tgtggtgtgt atatgtgtgt
     2161 gtgtgtgaga gtgctgtgtg tgcgtgtgca cgtgtgtgtt gacaaatgaa gtgtgttcat
     2221 tttgtatgta ttaaactgtc ttgccaaacc taagctctaa gatatttggg gacattttaa
     2281 aaatcacttt aagtgaaaaa tttcagcttt actgggcatt ctggaagcaa aatatattat
     2341 gctgagaata aagtaagaac ctagtcgcaa cactaccagg atggtggaaa atgcagcgga
     2401 ccaaatgcat aagcctgtga gattagcagt ggtcctttca gctttccttc tacctcaaag
     2461 tgcatttcca ggatccgtct gaagagggag gcagatgcag acagagcctt acttagagta
     2521 gattagacag ctgtggtgga tggtttggag gaagaagatt tttacatcta gctgtagaaa
     2581 aaggcgtttt ggtttgggta aatatgcgta ttttttactt tgaacaccat tgaagatagt
     2641 tcctttttaa tatctggacc ttcactcctt gtccatcttg ccttgacact tactgtattc
     2701 tgagtgggta gcgtgtgcca ttctggggca gtttcttcct accaggtgct tctgaggccc
     2761 gggctgtatt ctgtttctct tggaccttaa cgctcaccca gagaagggga agttaatgaa
     2821 ggagcagtat cagctgtgac ggtcccggat cctctgtagg aagcgatcag tgcagttgct
     2881 ccaacttcag tagttcagcc agagacagac caagagaagg tttaaaatgc catcaaagta
     2941 tctgcgccca ggagaggaat tgttattagc tcagtacgca gataggttga gggagcagca
     3001 gccatgattc cttggcagaa tgtcatcatg aagttagatt ctgtggcctg tgttcaagtt
     3061 tagcttgtta ggtggaaaca tgagaacctt agcctttgaa gtttggctta taatgtgaga
     3121 gagcttgcca aaaacaagtc ctacatatac tgtatctagg aaggagtctt taagaaattt
     3181 tttaaatgaa gagattaaaa attatatcaa agtagactag ggccatacct caatagtcag
     3241 agtgcttact tcatgtgctc aagaaccagc agtgcagaaa ataataggag atgagaagga
     3301 agtaagatct tagtgcagcg ctctcactgg tcatgtctgt taccagtcag gatcttgcca
     3361 catttacgtc atctgttcct tttttatatt aaagtctcag gcatcattct gtgtccctgc
     3421 agtaaatggt ttggtactta caggtaacca cggcaactac atcatcctta gcaacagcag
     3481 cagctgcctt tggtctgtct tacatacgct tggtgcacga tggttctgct ttgagtgagt
     3541 tcctcagaag gttccgatgt agctagttta ggaagcactg gaaattctta tgccatcctt
     3601 aaggttggag ttaggatgtc acagttattg gcacaattgc taacttataa gtgccatttt
     3661 cagatagagg aagcacttgg ggttattgac gagagaggga ctcatgagta cctttagatg
     3721 caattttctc agtagccgaa gcctcaaccc catgcgctcc actctgattg gttgaggccg
     3781 tttagagaaa gaatcttaaa atgcatcaaa cctctagaaa gtctgtttta agaaaatgca
     3841 gtttgccttt atgaggatga gctcatgagc tatgccatgc ttgccttgga cactgcttcc
     3901 tcatggctct catcggctta tgtcaagtgt cagtgtcatg acgagaacag atggggactg
     3961 gcctgctttc cctttgtggg cttgaggggt gtgctgacca caccgtgcta gagcggcgag
     4021 gaggtgtgga aggggtggct ggagggacgc atgtagctcc tcagccatgc cagtgttgat
     4081 ggcatccagt tttgccaggg gctgggctgc ctcctgaggc tgagagcttt ttgtctgtct
     4141 tctccagggt ggatttgttg atggtatgtg gaaggaacag attttaagga agagaggaag
     4201 agaagaaaag gatgaagcaa atgaatagtc aagaaaggag agagagagag gtaaaagaat
     4261 gacagaaggc taagtgagcg aaagatgaag gaagggggga gatgggtagg tgcagatgaa
     4321 gggaactgga aacatggggt cccctgccta ggtcagtgct tgccctacac tgcctggagc
     4381 ctgcggctgg ggatagcaga gccagtcttg ttggagtcat tgataacaga cacgtttttt
     4441 ggtcaccttg ttcattgagt ggtagttgtc cttttatttt ctttgcctgt ggaaacacac
     4501 atactttcca ttttaatgtc ctttagctta tccagggtaa gtctgtgaag gaaacagctt
     4561 tgtaatgtct aaatctctcc tatccgtttt tccctagcac tgctaattag aggccagtat
     4621 gaccattttg tttgtttgtt tgtttacttt taagtatagc tatttccaac ttatatataa
     4681 aaatctcctc agggagaact gaaatattat aaaataatcc ttagcttgcg gcgttgccta
     4741 gaatggtggc tagggcagtg gttacaccta cctgttcctc cccgtcccag tggggatact
     4801 ttcagtggaa ctggtgagtg actcaggaga cagatggtgg aaacattaaa agcaaacctt
     4861 taaagaatac tcattgtcag gacagagagt ttgctcaatg attctgagca cttggtccca
     4921 gcacccacat ggtggtccac aactacctat aactccaatt ccaagggatc caacaccctc
     4981 ttctaacctc tgggcaccag acccatatgt ggtgcacatg cacacacaca ggcaacacat
     5041 acatataatc taaaaacatt taaaaatact cactgtcctt tccagttgct tataataaat
     5101 agcacaagca cagttcgctc ctttgagatg ttcttattaa tgtggttgag ctgtcttttc
     5161 aaaaatgttt ctggtttgtt ttttgttttt gtttttgaat agagaagaaa aatagaatgt
     5221 gcaatatgtc cggcgtgggg ccagttatcc atttattaag tgtaatttca agtgtcttaa
     5281 agtaataacc accttactgc attttaatac ccggtggaag taaccgaggt ggccagtttt
     5341 gccgtggtca tcctttacac tgccaaagca gcccctttct tctagaatct acctaacttg
     5401 ttctgatagt tgtagttttt ttaattcatt gaagataaga ttaaaaaaaa aacaaaaccc
     5461 tgaggtatat agatttgaga ccgatgtcta aaagctgtta taaggatcac aactgggcgt
     5521 ggtggcacat gacctgttac ccagtacttg ggaaattgag gtgcatgcaa gggcagtatg
     5581 gcctttgttg agatttttgt ctcaagaagc aaaataaaaa caacaaaaaa acaaaacaaa
     5641 acaaaaaacc caaaacagaa aaacctctac aagtgtgtgc taatcagata tgtagtcctt
     5701 agagaatcgt gagacagtgt gtgcctgttg gcctggcaat ctacaccagg ttacatacca
     5761 gtgtcaggat tacttttcag aacttgtcac ctcatcctgg ccaataatta caagtatctc
     5821 ctgtgatttc cttagacttt tctataattt tatgtttcaa acagtcagga gttttgtagt
     5881 gaatttctct cagtaatgct gtgaatacca gatattttcc tatcaaactt gagaactgat
     5941 tgggacattt gacctgtgta gataaaacat gcagtcagac tattggagca tcttcacaca
     6001 cagcacacca tgaccgcacc ttctgaaagt tcatttagag atttcgacca cctatgccat
     6061 ttaaacagta aatcgttccc ctggggtaat acttctgtct gaactgttac aagtccaact
     6121 gttacaagtg gactttttaa aaacacaaaa ctaatagctg ttttcagctt ttgtattaaa
     6181 tctcttcagg gaatattgaa atgttataaa ataatccata gctgtggcgt tgttctagac
     6241 cgtgcctgtt ctgaatacag cagaacatgc ccttgtcgca cgattaccgt tatatgtgag
     6301 ggctgatcag agggatttga tgcgctctgt atcagaaggt gtctgagatg gaaatgagag
     6361 cctggaacca gctgcagggg ctcacgtctg ccaagcattt gcttgggtct gttactgtgc
     6421 tgagcacagt ggcctgcggc tgcgggaagg catcgtgatg aaccatgcta tgtagacatt
     6481 actgcctcga aactgctttt accttaaaaa tattttggtt tttataataa tgtgaatatt
     6541 ttaagtcatt tgtgtatctt gagaactctt aatggggagt ataaaagtat gaatttgggg
     6601 tctagcttac cagtattgga agatgccttg ctctgttctg gaaggttcag ctcaggtgtt
     6661 tcttgagaag ctgtatgctg ttactaaata tgtactcaat aaatgttgga tttcctca
//
