LOCUS       NM_001013171            2835 bp    mRNA    linear   ROD 01-JUN-2024
DEFINITION  Rattus norvegicus GULP PTB domain containing engulfment adaptor 1
            (Gulp1), mRNA.
ACCESSION   NM_001013171 XM_234765
VERSION     NM_001013171.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2835)
  AUTHORS   Martins-Silva,C., Ferreira,L.T., Cyr,M., Koenen,J., Fernandes,D.R.,
            Carvalho,N.R., Ribeiro,C.B., Marion,S., Chavez-Olortegui,C.,
            Prado,M.A. and Prado,V.F.
  TITLE     A rat homologue of CED-6 is expressed in neurons and interacts with
            clathrin
  JOURNAL   Brain Res 1119 (1), 1-12 (2006)
   PUBMED   17007823
  REMARK    GeneRIF: The present findings suggest that CED-6 may have a role in
            endocytic trafficking or signaling in neurons.
REFERENCE   2  (bases 1 to 2835)
  AUTHORS   Su,H.P., Nakada-Tsukui,K., Tosello-Trampont,A.C., Li,Y., Bu,G.,
            Henson,P.M. and Ravichandran,K.S.
  TITLE     Interaction of CED-6/GULP, an adapter protein involved in
            engulfment of apoptotic cells with CED-1 and CD91/low density
            lipoprotein receptor-related protein (LRP)
  JOURNAL   J Biol Chem 277 (14), 11772-11779 (2002)
   PUBMED   11729193
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC087053.1, CB738009.1 and BM390519.1.
            
            On Oct 19, 2007 this sequence version replaced NM_001013171.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC087053.1, SRR8487227.350737.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760384
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1296              BC087053.1         1-1296
            1297-1365           CB738009.1         82-150
            1366-2815           BC087053.1         1366-2815
            2816-2835           BM390519.1         1-20                c
FEATURES             Location/Qualifiers
     source          1..2835
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="Sprague-Dawley"
                     /db_xref="taxon:10116"
                     /chromosome="9"
                     /map="9q22"
     gene            1..2835
                     /gene="Gulp1"
                     /gene_synonym="CED-6"
                     /note="GULP PTB domain containing engulfment adaptor 1"
                     /db_xref="GeneID:314543"
                     /db_xref="RGD:1306380"
     exon            1..61
                     /gene="Gulp1"
                     /gene_synonym="CED-6"
                     /inference="alignment:Splign:2.1.0"
     exon            62..133
                     /gene="Gulp1"
                     /gene_synonym="CED-6"
                     /inference="alignment:Splign:2.1.0"
     CDS             106..1020
                     /gene="Gulp1"
                     /gene_synonym="CED-6"
                     /note="cell death protein 6 homolog; PTB domain adapter
                     protein CED-6; GULP, engulfment adaptor PTB domain
                     containing 1"
                     /codon_start=1
                     /product="PTB domain-containing engulfment adapter protein
                     1"
                     /protein_id="NP_001013189.1"
                     /db_xref="GeneID:314543"
                     /db_xref="RGD:1306380"
                     /translation="MNRAFSRKKDKTWMHMPEALSKHYVPYNAKFLGSTEVEQPKGTE
                     VVRDAVRKLKFARHIKKSEGQKIPKVELQISIYGVKILEPKTKEVQHNCQLHRISFCA
                     DDKTDKRIFTFICKDSESNKHLCFVFDSEKCAEEITLTIGQAFDLAYRKFLESGGKDV
                     ETRKQIAGMQKRIQDLETENMELKNKVQDLENRLRTTQVSSTPAGGVTVTSPSTDIFD
                     MIPFSPISHPSPTSAGNGTQLPPIPSRSSEIKRDLFGAEPFDPFNCGAGDFPPDIQSK
                     LDEMQEGFKMGLTLEGTVFCLDPLDSRC"
     exon            134..195
                     /gene="Gulp1"
                     /gene_synonym="CED-6"
                     /inference="alignment:Splign:2.1.0"
     exon            196..267
                     /gene="Gulp1"
                     /gene_synonym="CED-6"
                     /inference="alignment:Splign:2.1.0"
     exon            268..366
                     /gene="Gulp1"
                     /gene_synonym="CED-6"
                     /inference="alignment:Splign:2.1.0"
     exon            367..504
                     /gene="Gulp1"
                     /gene_synonym="CED-6"
                     /inference="alignment:Splign:2.1.0"
     exon            505..621
                     /gene="Gulp1"
                     /gene_synonym="CED-6"
                     /inference="alignment:Splign:2.1.0"
     exon            622..714
                     /gene="Gulp1"
                     /gene_synonym="CED-6"
                     /inference="alignment:Splign:2.1.0"
     exon            715..853
                     /gene="Gulp1"
                     /gene_synonym="CED-6"
                     /inference="alignment:Splign:2.1.0"
     exon            854..948
                     /gene="Gulp1"
                     /gene_synonym="CED-6"
                     /inference="alignment:Splign:2.1.0"
     exon            949..2820
                     /gene="Gulp1"
                     /gene_synonym="CED-6"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cgggtccccg gagctcctgt gctttaccca gcccagcgac cgcatccctc tacaaagcag
       61 gggtactggg cattactgag ctgagcagtt gggagtatca acatcatgaa ccgggctttc
      121 agcaggaaga aagacaaaac atggatgcat atgcctgaag ccttatcaaa acattacgtt
      181 ccctataatg caaagtttct tggcagtact gaagtggagc agccaaaggg aacagaagtt
      241 gtgagagatg ctgtcaggaa gctgaagttt gcaagacaca tcaagaaatc tgaaggccag
      301 aagattccta aagttgaatt gcaaatatca atttatggag tgaaaattct cgaaccaaaa
      361 acaaaggaag ttcaacacaa ctgccagctt catagaatat cattttgtgc agatgataaa
      421 accgacaaga ggattttcac cttcatatgc aaagattctg agtcaaacaa acatttgtgt
      481 tttgtgtttg acagcgaaaa gtgtgctgaa gaaattacat taacaattgg ccaagcattt
      541 gacttagcat acaggaaatt tctagaatct ggaggaaaag atgtggaaac aagaaaacag
      601 attgctggaa tgcagaaaag aatccaagac ttagaaacag aaaatatgga acttaaaaat
      661 aaagtacaag atttagaaaa ccggttgaga acaactcaag tgtcctcgac tccagctggt
      721 ggtgtgacag tgacttctcc ttccactgac atctttgaca tgattccatt ttccccaata
      781 tcacacccgt ctccaacctc tgctggcaat ggcacacagc taccacccat acctagcaga
      841 tcttcagaga tcaaacggga cctttttgga gctgaacctt ttgacccatt taactgtgga
      901 gcaggggact ttcctcctga tattcagtcc aaattggatg agatgcagga ggggttcaaa
      961 atgggactaa ctcttgaagg aacagtattt tgtctcgacc cattagacag caggtgctga
     1021 catcacaaat gagtgatcct gacatactta ttttgtttat atacatatat atcattcatt
     1081 attttaagac agctattata cttgtgccaa tatatttttg aatatataaa tgtttttaga
     1141 tttgttgaag taacattctc ctcaatttca ctgttgattt atcttttatt ttaaacagga
     1201 ctcagtataa tgtatattgg acttttatgt ttccttcttt gttattggta aatttgtaat
     1261 tgaaaggcaa gtttcataaa tgtctgcctt atttgcattt taaattatca ttaccttgac
     1321 atttaagctc atcctcagga tattagttca ttatcattgt cccaaaacgc catacctaga
     1381 tatcttccaa agacctgaag agacaggcca atatacatgc tctattttga caccaataaa
     1441 caggctacca gtttttagct gtatgctatt tgtgattaaa aagtttgcct cattatgaaa
     1501 gtctaaattt tagctattac gctaccagct tactaaattc tatctggtaa aataagaaaa
     1561 taggttttag tagtaatcac ataaacatat ttagaatatt ggtaaatata aaataatatc
     1621 agtcattcaa gttatattat gcaaatgttt aatttgtctc aaaagtaaca attgaaaaat
     1681 tgcttccttg gaaaacttaa aaattcattt ctaatatgca ctctgggtta gcctctgctc
     1741 cagtatttta agaaatgaag tttttgcttt ctgcagatgt aatgcctatt gcctgtgctt
     1801 atgtaaccaa tattctgcag ttatcatgtg acgtggcatt actctcaccc atcttatgca
     1861 tcaatgccac attagttttt atatcttaaa attttggtgg ggtattttac ttaaatttaa
     1921 gaaaattcaa caattttaat ttttatttgc tttaagtcag aatttcattt ttccacacaa
     1981 aacaaaactc atcatcttcg tcttgactat gagcaataaa actttccaga actcattctg
     2041 atgtactaat gaacctgtcc tttgaacgta tatgcttcca aaatatttcc ccacgatgta
     2101 aaatactacc agtgcagaaa aaaaatgact gtcgaaagtt ctaatttggt ttatcacaaa
     2161 gaaggaaaat aaagtaatga aaatctgggc ttagtttgtg agaattttac caaaactaag
     2221 tagatatgtt tactgccgga gacttatgga agtgttacag gtaccttttc agtagaagca
     2281 gaacagaaat caatgggctt acacaacttt ctgtttgaat gattatgctc tatgacatac
     2341 atgagccttc ctgctgacgt tctgttacac ctgctaagtt aaaccttaat tagcaggtac
     2401 tgtgtgtttc atcagaaact ctttgaagtt cttgattctc aactagtact ttggaatttg
     2461 tataatgagg atgtttagag gccatctata tggctttttt aacagataga atttgtattt
     2521 ttcttgtact tttaaaggct ttatgtaata gatatgtatt tagcaaacat ttagtatcaa
     2581 ttgtaacacg atagaatact aagatgatat ttgcacattt actgtatgtt acttacctgt
     2641 ttttaatggt gatctgttct gctactggca tgatcaaata atacataaaa ttggtcatta
     2701 atatgaacat ttacttcacc agtgaatttt taatgaagac atgattggaa atttaatttc
     2761 tatgtaaact caacgatatg tttgattttg ctgaaaataa aggattttaa ataaattaaa
     2821 aaaaaaaaaa aaaaa
//
