LOCUS       NM_133541               6905 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus general transcription factor IIIC subunit 1
            (Gtf3c1), mRNA.
ACCESSION   NM_133541 XM_006230205
VERSION     NM_133541.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 6905)
  AUTHORS   Vannini,A.
  TITLE     A structural perspective on RNA polymerase I and RNA polymerase III
            transcription machineries
  JOURNAL   Biochim Biophys Acta 1829 (3-4), 258-264 (2013)
   PUBMED   23031840
  REMARK    Review article
REFERENCE   2  (bases 1 to 6905)
  AUTHORS   Ghosh,D., Lippert,D., Krokhin,O., Cortens,J.P. and Wilkins,J.A.
  TITLE     Defining the membrane proteome of NK cells
  JOURNAL   J Mass Spectrom 45 (1), 1-25 (2010)
   PUBMED   19946888
REFERENCE   3  (bases 1 to 6905)
  AUTHORS   de Planell-Saguer,M., Schroeder,D.G., Rodicio,M.C., Cox,G.A. and
            Mourelatos,Z.
  TITLE     Biochemical and genetic evidence for a role of IGHMBP2 in the
            translational machinery
  JOURNAL   Hum Mol Genet 18 (12), 2115-2126 (2009)
   PUBMED   19299493
REFERENCE   4  (bases 1 to 6905)
  AUTHORS   Dumay-Odelot,H., Marck,C., Durrieu-Gaillard,S., Lefebvre,O.,
            Jourdain,S., Prochazkova,M., Pflieger,A. and Teichmann,M.
  TITLE     Identification, molecular cloning, and characterization of the
            sixth subunit of human transcription factor TFIIIC
  JOURNAL   J Biol Chem 282 (23), 17179-17189 (2007)
   PUBMED   17409385
REFERENCE   5  (bases 1 to 6905)
  AUTHORS   Lagna,G., Kovelman,R., Sukegawa,J. and Roeder,R.G.
  TITLE     Cloning and characterization of an evolutionarily divergent
            DNA-binding subunit of mammalian TFIIIC
  JOURNAL   Mol Cell Biol 14 (5), 3053-3064 (1994)
   PUBMED   8164661
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000001.1.
            
            On or before Sep 4, 2015 this sequence version replaced
            XM_006230205.2, NM_133541.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: L28801.1, SRR26360194.1989805.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760389 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-273               JAXUCZ010000001.1  189700576-189700848 c
            274-483             JAXUCZ010000001.1  189697237-189697446 c
            484-660             JAXUCZ010000001.1  189692890-189693066 c
            661-804             JAXUCZ010000001.1  189692492-189692635 c
            805-901             JAXUCZ010000001.1  189690320-189690416 c
            902-1025            JAXUCZ010000001.1  189686810-189686933 c
            1026-1187           JAXUCZ010000001.1  189673985-189674146 c
            1188-1303           JAXUCZ010000001.1  189671743-189671858 c
            1304-1616           JAXUCZ010000001.1  189670189-189670501 c
            1617-1819           JAXUCZ010000001.1  189669332-189669534 c
            1820-1956           JAXUCZ010000001.1  189666154-189666290 c
            1957-2110           JAXUCZ010000001.1  189664740-189664893 c
            2111-2214           JAXUCZ010000001.1  189662539-189662642 c
            2215-2399           JAXUCZ010000001.1  189661640-189661824 c
            2400-2669           JAXUCZ010000001.1  189661205-189661474 c
            2670-2815           JAXUCZ010000001.1  189660928-189661073 c
            2816-2913           JAXUCZ010000001.1  189660045-189660142 c
            2914-3010           JAXUCZ010000001.1  189659605-189659701 c
            3011-3188           JAXUCZ010000001.1  189659318-189659495 c
            3189-3327           JAXUCZ010000001.1  189656004-189656142 c
            3328-3463           JAXUCZ010000001.1  189655528-189655663 c
            3464-3542           JAXUCZ010000001.1  189655153-189655231 c
            3543-3731           JAXUCZ010000001.1  189654835-189655023 c
            3732-3889           JAXUCZ010000001.1  189651886-189652043 c
            3890-4032           JAXUCZ010000001.1  189650315-189650457 c
            4033-4114           JAXUCZ010000001.1  189648811-189648892 c
            4115-4227           JAXUCZ010000001.1  189647515-189647627 c
            4228-4290           JAXUCZ010000001.1  189645234-189645296 c
            4291-4384           JAXUCZ010000001.1  189644407-189644500 c
            4385-4557           JAXUCZ010000001.1  189642159-189642331 c
            4558-4845           JAXUCZ010000001.1  189641138-189641425 c
            4846-5105           JAXUCZ010000001.1  189640277-189640536 c
            5106-5395           JAXUCZ010000001.1  189639196-189639485 c
            5396-5900           JAXUCZ010000001.1  189637610-189638114 c
            5901-5940           JAXUCZ010000001.1  189636986-189637025 c
            5941-6133           JAXUCZ010000001.1  189636088-189636280 c
            6134-6905           JAXUCZ010000001.1  189634645-189635416 c
FEATURES             Location/Qualifiers
     source          1..6905
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q36"
     gene            1..6905
                     /gene="Gtf3c1"
                     /gene_synonym="TF3C-alpha; TFIIIC220"
                     /note="general transcription factor IIIC subunit 1"
                     /db_xref="GeneID:171063"
                     /db_xref="RGD:621048"
     exon            1..273
                     /gene="Gtf3c1"
                     /gene_synonym="TF3C-alpha; TFIIIC220"
                     /inference="alignment:Splign:2.1.0"
     CDS             53..6361
                     /gene="Gtf3c1"
                     /gene_synonym="TF3C-alpha; TFIIIC220"
                     /note="TFIIIC 220 kDa subunit; TFIIIC box B-binding
                     subunit; transcription factor IIIC subunit alpha;
                     transcription factor IIIC 220 kDa subunit; general
                     transcription factor III C 1; general transcription factor
                     IIIC, polypeptide 1, alpha"
                     /codon_start=1
                     /product="general transcription factor 3C polypeptide 1"
                     /protein_id="NP_598225.2"
                     /db_xref="GeneID:171063"
                     /db_xref="RGD:621048"
                     /translation="MDALESLLDEVALEGLDGLCLPALWSRLESRSPAFPLPLEPYTQ
                     EFLWRALVTHPGISFYEEPRERPDLQLQDRYEEIDLETGILESRRDPVTLEDVYPIHM
                     ILENKDGIQGSCRYFKERKDITSSIRSKCLQPRCTMVEAFSRWGKKLIIVASQDMRYR
                     ALIGLEGDPDLKLPDFSYCILERLGRSRWQGELQRDLHTTAFKVDAGKLHYHRKILNK
                     NGLITMQSHVIRLPTGAQQHSILLLLNRFHVDRRSKYDILMEKLSMMLSTRSNQIETL
                     GKLREELGLCERTFKRLYQYMLNAGLAKVVSLPLQEIHPECGPCKTKKGTDVMVRCLK
                     LLKEFRRKMEDDHDDDDDEEAISKAVPPVDIVFERDMLTQTYELIERRGTKGISQAEI
                     RVAMNVGKLEARMLCRLLQRFKVVKGFMEDEGRQRTTKYISCVFAEESDLSRQYAREK
                     ARGELLTTVSLASVQDESLMPEGEEAFLSDSESEEESSCSGKRRGRGSRGHSRASGDA
                     GPGSRPHHSTPAKGGWKVLNLHPLKKPKSAAVERSRRSSACRDGLDTSSSSELNIPFD
                     PHSMDSHSGDIAVIEEVRLDNPKEGGGSQKGGRHGSGQDKPHKTYRLLKRRNLIIEAV
                     TNLRLIESLFTIQKMIMDQEKQEGVSTKCCKKSIIRLVRNLSEEGLLRLYRTTVIQDG
                     IKKKVDLVVHPSMDQNDPLVRSAIEQVRFRISNSSTANRVKVPPAPAPQEEAEEGNQE
                     PEVPSRSADSEANTSSKPESTRVKKTDEKMGITPLKNYKPVIVPGLGRSIGFLPKMPR
                     LRVMHLFLWYLVYGHPASHTGEQPTFHSERKTGKQEPSRPGVQPSSGDDWDSSEAKNS
                     TESSSWEAEMELSTERVYVDEISWMRYVPPIPIHRDFGFGWALVSDILLCLPLSIFVQ
                     VVQVSYKVDNLEDFLNDPLKKHTLIRFLPRHIRQQLLYKRRYIFSVVENLQRLCYMGL
                     LQFGPTEKFQDKDQVFVFLKKNAVIVDTTICDPHYNLAHSSRPFERRLYVLDSMQDVE
                     SYWFDLQCICLNTPLGVVRCPCAQKICPDPGSDPEGSLRKEQESAMDKHNLERKCAML
                     EYTTGSREVVDEGLVPGDGLGAAGLDSSFYAHLKRNWVWTSYIINKARKNNTSENGLT
                     GRLQTFLSKRPMPLGSGGSGRLPLWSEGKADAELCADKEEHFELDREPTPGRNRKVRG
                     GKSQKRKRLKKEPIRKTKRRRRGEHPEAKSKKLRYQDEADQNALRMMTRLRVSWSMQE
                     DGLLMLCRIASNVLNTKVKGPFVTWQVVRDILHATFEESLDKTSHSVGRRARYIVKNP
                     QAFMNYKVCLAEVYQDKALVGDFMSRKDNYEDPKVCAKEFKEFVEKLKEKFSSGLRNP
                     NLEIPDTLQELFAKYRVLAIGDEKDRVRKEDELNSVEDIHFLVLQNLIQSTLSLSNSQ
                     SNSCQSFQIFRLYREFREPVLVRAFMECQKRSLVNRRRVSHSQGPKKNRAVPFVPMSY
                     QLSQSYYKLFTWRFPTTVCTESFQFYDRLRANGILDQPDHFSFKDMDSNDPSSDLVAF
                     SLDSPGGHCVTALALFSLGLLSVDVRIPEQIVVVDSSMVESEVMKSLGKDGGLDDDDE
                     EEDLDEGSGTKRQSVEVKAHQASHTKYLLMRGYYTVPGMVSTRNLNPNDSIVVNSCQV
                     KFRLRNTPAPTHLGPTGPTATPLEELQAGPSCLPASFTSLVDPQLHTRCPEEFAHQMA
                     QSGYSPEDVAASLEILQAVAAADCFGVDREKLSRQFSALEKIADKRTRTFLDYIQDLL
                     EQQQVMEVGGNTVRLVAMASAQPWLLPSVRLKDVEIDTKASGDDSQSRLPAGSSIEDH
                     TSEGAPIPPVSSNGTKKRPYCSIQSPETDAEEATRLPAKKPTLQDVCVAASPRPGTEE
                     QTEAQAQFAAPEDAGAEGPRQESQESVGVSGLEQLGCEFQLPENSEDPRGLTESNMAQ
                     VAWESGCERVCFVGRPWRGVDGRLNMPVCKGMMEAVLYHIMSRPGVPESCLLQYYQGV
                     LQPVAVLELLRGLESLGCIQKRMLKKPASVSLFSRPVVEGLGQASEAEALSCQGSTVT
                     FYEPTLDCTIRLGRVFPHDINWNKWIHL"
     exon            274..483
                     /gene="Gtf3c1"
                     /gene_synonym="TF3C-alpha; TFIIIC220"
                     /inference="alignment:Splign:2.1.0"
     exon            484..660
                     /gene="Gtf3c1"
                     /gene_synonym="TF3C-alpha; TFIIIC220"
                     /inference="alignment:Splign:2.1.0"
     exon            661..804
                     /gene="Gtf3c1"
                     /gene_synonym="TF3C-alpha; TFIIIC220"
                     /inference="alignment:Splign:2.1.0"
     exon            805..901
                     /gene="Gtf3c1"
                     /gene_synonym="TF3C-alpha; TFIIIC220"
                     /inference="alignment:Splign:2.1.0"
     exon            902..1025
                     /gene="Gtf3c1"
                     /gene_synonym="TF3C-alpha; TFIIIC220"
                     /inference="alignment:Splign:2.1.0"
     exon            1026..1187
                     /gene="Gtf3c1"
                     /gene_synonym="TF3C-alpha; TFIIIC220"
                     /inference="alignment:Splign:2.1.0"
     exon            1188..1303
                     /gene="Gtf3c1"
                     /gene_synonym="TF3C-alpha; TFIIIC220"
                     /inference="alignment:Splign:2.1.0"
     exon            1304..1616
                     /gene="Gtf3c1"
                     /gene_synonym="TF3C-alpha; TFIIIC220"
                     /inference="alignment:Splign:2.1.0"
     exon            1617..1819
                     /gene="Gtf3c1"
                     /gene_synonym="TF3C-alpha; TFIIIC220"
                     /inference="alignment:Splign:2.1.0"
     exon            1820..1956
                     /gene="Gtf3c1"
                     /gene_synonym="TF3C-alpha; TFIIIC220"
                     /inference="alignment:Splign:2.1.0"
     exon            1957..2110
                     /gene="Gtf3c1"
                     /gene_synonym="TF3C-alpha; TFIIIC220"
                     /inference="alignment:Splign:2.1.0"
     exon            2111..2214
                     /gene="Gtf3c1"
                     /gene_synonym="TF3C-alpha; TFIIIC220"
                     /inference="alignment:Splign:2.1.0"
     exon            2215..2399
                     /gene="Gtf3c1"
                     /gene_synonym="TF3C-alpha; TFIIIC220"
                     /inference="alignment:Splign:2.1.0"
     exon            2400..2669
                     /gene="Gtf3c1"
                     /gene_synonym="TF3C-alpha; TFIIIC220"
                     /inference="alignment:Splign:2.1.0"
     exon            2670..2815
                     /gene="Gtf3c1"
                     /gene_synonym="TF3C-alpha; TFIIIC220"
                     /inference="alignment:Splign:2.1.0"
     exon            2816..2913
                     /gene="Gtf3c1"
                     /gene_synonym="TF3C-alpha; TFIIIC220"
                     /inference="alignment:Splign:2.1.0"
     exon            2914..3010
                     /gene="Gtf3c1"
                     /gene_synonym="TF3C-alpha; TFIIIC220"
                     /inference="alignment:Splign:2.1.0"
     exon            3011..3188
                     /gene="Gtf3c1"
                     /gene_synonym="TF3C-alpha; TFIIIC220"
                     /inference="alignment:Splign:2.1.0"
     exon            3189..3327
                     /gene="Gtf3c1"
                     /gene_synonym="TF3C-alpha; TFIIIC220"
                     /inference="alignment:Splign:2.1.0"
     exon            3328..3463
                     /gene="Gtf3c1"
                     /gene_synonym="TF3C-alpha; TFIIIC220"
                     /inference="alignment:Splign:2.1.0"
     exon            3464..3542
                     /gene="Gtf3c1"
                     /gene_synonym="TF3C-alpha; TFIIIC220"
                     /inference="alignment:Splign:2.1.0"
     exon            3543..3731
                     /gene="Gtf3c1"
                     /gene_synonym="TF3C-alpha; TFIIIC220"
                     /inference="alignment:Splign:2.1.0"
     exon            3732..3889
                     /gene="Gtf3c1"
                     /gene_synonym="TF3C-alpha; TFIIIC220"
                     /inference="alignment:Splign:2.1.0"
     exon            3890..4032
                     /gene="Gtf3c1"
                     /gene_synonym="TF3C-alpha; TFIIIC220"
                     /inference="alignment:Splign:2.1.0"
     exon            4033..4114
                     /gene="Gtf3c1"
                     /gene_synonym="TF3C-alpha; TFIIIC220"
                     /inference="alignment:Splign:2.1.0"
     exon            4115..4227
                     /gene="Gtf3c1"
                     /gene_synonym="TF3C-alpha; TFIIIC220"
                     /inference="alignment:Splign:2.1.0"
     exon            4228..4290
                     /gene="Gtf3c1"
                     /gene_synonym="TF3C-alpha; TFIIIC220"
                     /inference="alignment:Splign:2.1.0"
     exon            4291..4384
                     /gene="Gtf3c1"
                     /gene_synonym="TF3C-alpha; TFIIIC220"
                     /inference="alignment:Splign:2.1.0"
     exon            4385..4557
                     /gene="Gtf3c1"
                     /gene_synonym="TF3C-alpha; TFIIIC220"
                     /inference="alignment:Splign:2.1.0"
     exon            4558..4845
                     /gene="Gtf3c1"
                     /gene_synonym="TF3C-alpha; TFIIIC220"
                     /inference="alignment:Splign:2.1.0"
     exon            4846..5105
                     /gene="Gtf3c1"
                     /gene_synonym="TF3C-alpha; TFIIIC220"
                     /inference="alignment:Splign:2.1.0"
     exon            5106..5395
                     /gene="Gtf3c1"
                     /gene_synonym="TF3C-alpha; TFIIIC220"
                     /inference="alignment:Splign:2.1.0"
     exon            5396..5900
                     /gene="Gtf3c1"
                     /gene_synonym="TF3C-alpha; TFIIIC220"
                     /inference="alignment:Splign:2.1.0"
     exon            5901..5940
                     /gene="Gtf3c1"
                     /gene_synonym="TF3C-alpha; TFIIIC220"
                     /inference="alignment:Splign:2.1.0"
     exon            5941..6133
                     /gene="Gtf3c1"
                     /gene_synonym="TF3C-alpha; TFIIIC220"
                     /inference="alignment:Splign:2.1.0"
     exon            6134..6905
                     /gene="Gtf3c1"
                     /gene_synonym="TF3C-alpha; TFIIIC220"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcctcggcgg cgaggtgcgc aggcgctccg ggcgctgcta actgaagagg ccatggacgc
       61 gctcgagtcg ttgttggacg aggtggccct ggaggggctc gacggcctgt gcctgcccgc
      121 gctgtggagc cgcctggaat cccgctcgcc tgccttccct ttgccgctgg aaccctacac
      181 gcaggagttt ctgtggcggg ccttagtcac gcacccgggc atcagtttct acgaggagcc
      241 gcgagagcga cctgacctgc agctccaaga ccgatatgaa gaaatcgact tggaaactgg
      301 aattttggag tccaggaggg acccagtcac tctggaagat gtctacccca ttcatatgat
      361 cttagagaat aaggatggca tccagggctc ctgccgatac tttaaggaga gaaaggacat
      421 caccagtagc atcaggagca agtgtttgca gcctcgttgt acaatggtag aagccttcag
      481 caggtggggt aagaagctca tcattgtggc ttcccaggac atgcgatacc gggccttgat
      541 aggcctagag ggggatcctg atctgaagct tcctgatttc tcctactgca ttttggagcg
      601 gttaggtcga tcgagatggc aaggggagct gcaacgagac cttcacacca ccgctttcaa
      661 ggtcgacgct gggaagcttc attatcacag gaaaattttg aacaagaatg ggctcattac
      721 aatgcagtca cacgtgatcc gactgcctac tggagcccag caacactcca tcctcctcct
      781 ccttaaccgg tttcatgtag acaggaggag caagtacgac atcctcatgg agaagctgtc
      841 tatgatgctg agcacacgga gcaaccagat cgagactctg ggcaagctga gggaggagct
      901 gggactgtgt gaaaggacgt tcaagcgtct gtaccagtac atgctgaatg ctgggctggc
      961 caaagtggtg tcccttccct tgcaggagat tcaccctgag tgtggtccct gtaagaccaa
     1021 gaaagggact gatgtcatgg ttcggtgcct taagctcctg aaggagttca ggcgaaagat
     1081 ggaagacgac catgacgacg atgacgatga agaggccatc tccaaggctg tacctcccgt
     1141 ggacatcgtg tttgagcggg acatgctcac gcagacctac gagctcattg agcgcagagg
     1201 aacgaaagga atttcccaag ctgagatccg agttgctatg aatgtgggaa aactggaagc
     1261 aagaatgctg tgtcggctcc ttcagaggtt caaggttgtc aagggattca tggaagatga
     1321 aggccggcag aggaccacca agtacatttc ctgtgtattt gcggaggaga gtgacttgag
     1381 ccgccaatat gcgcgtgaaa aggcccgagg agagctgcta accactgtga gcctcgcctc
     1441 agtgcaagat gaatccctca tgcctgaggg tgaagaggcc ttcctctctg actccgaaag
     1501 tgaggaagag agcagctgca gtggcaagcg taggggccga gggtcccggg ggcattcaag
     1561 agcctctggg gatgctgggc ctggctctcg gcctcatcac tccactccag ccaagggcgg
     1621 gtggaaagtc ctaaatctgc acccattaaa gaagcccaaa agtgccgctg tggaaagatc
     1681 ccgccgaagc tctgcttgta gggatggcct ggacaccagc agctcatccg agctcaatat
     1741 accctttgac cctcacagca tggacagtca cagtggtgac atcgctgtga ttgaggaggt
     1801 ccggcttgat aaccccaagg agggtggtgg ctcccagaag ggcggacggc atggctcagg
     1861 ccaggacaag cctcacaaaa cataccgact gctaaagcgc agaaatctga ttatagaagc
     1921 tgtcaccaac ctccgcctga ttgagagcct gttcacgatt cagaagatga tcatggacca
     1981 ggagaagcaa gagggtgtct ccaccaaatg ctgtaagaag tccattatcc gcttggtgcg
     2041 gaacctgtct gaggagggtc tcttgagatt gtataggact acagtcattc aagatggcat
     2101 caagaagaag gtagacctgg tcgtgcaccc ttccatggac cagaatgacc ctcttgtgag
     2161 aagtgctatt gagcaggttc gcttccggat ctccaactca agcacagcaa acagggttaa
     2221 agttccaccg gccccagcac cccaagagga agcagaagag ggaaaccaag aaccagaggt
     2281 cccaagtaga tcagcagact ctgaagcgaa cacatcctcg aagccagaaa gcacacgggt
     2341 gaaaaagaca gatgagaaaa tgggcataac cccactcaag aattacaaac ctgtcatagt
     2401 tcctggactt gggcgctcca tagggttcct tcccaagatg ccacgccttc gggtgatgca
     2461 cctgttcctg tggtacctgg tgtatgggca tcctgccagc cacactgggg aacagcctac
     2521 tttccacagt gagaggaaaa caggcaagca ggagcccagc agaccagggg tccagccctc
     2581 ctcaggagat gactgggact cctctgaagc caaaaacagc acagaaagca gctcctggga
     2641 ggcagaaatg gaactctcca cagagagagt gtatgtggat gagatctcat ggatgcgcta
     2701 cgtccctccc atccccatcc acagagactt cggctttggc tgggctcttg tcagtgacat
     2761 tcttctctgc cttcccctct ccatctttgt ccaagttgtt caagtcagct acaaggtgga
     2821 taacctggag gattttctga atgaccctct gaagaagcac acactgatcc gcttcctccc
     2881 taggcacatc cggcagcagc tactgtataa gaggcggtat attttctcgg tggtggagaa
     2941 cctgcaacgg ctgtgctaca tggggctgct acagtttgga cccacagaga agtttcagga
     3001 taaagaccag gtctttgttt tcctgaagaa gaatgcagtc attgtggaca ccaccatctg
     3061 tgacccacat tacaacctgg cccacagcag ccggcctttt gagagacgtc tctacgtctt
     3121 ggattccatg caggatgtgg aaagctactg gtttgacctg cagtgtatct gcctaaacac
     3181 cccactaggt gtggtgcgtt gtccatgtgc acagaagatc tgccctgatc cgggcagtga
     3241 cccagaaggc agcttgcgga aggagcaaga gagcgccatg gacaagcaca acctagagcg
     3301 caagtgtgcc atgctggagt ataccacggg gagccgagaa gttgtggatg aaggcttagt
     3361 ccctggggat ggactgggag ctgctgggct ggactctagc ttctatgcac acctgaagcg
     3421 caactgggtc tggaccagct atatcatcaa caaagccaga aagaacaaca cctccgaaaa
     3481 tgggctcaca ggaagactcc agactttcct gtctaagcgc ccaatgccac ttgggtctgg
     3541 aggcagtggc cgtctgcctc tctggtcaga ggggaaagct gatgctgagc tctgtgctga
     3601 caaagaggaa cactttgaac tggaccgaga acctacccct ggcaggaacc gaaaagtgcg
     3661 tgggggcaag agtcagaagc ggaagcggct gaagaaggag cccatcagga agaccaagcg
     3721 aaggagaaga ggagagcatc cagaagccaa aagcaaaaaa ctacgctacc aagatgaggc
     3781 tgaccagaac gccctccgga tgatgacccg gcttcgggtt tcttggtcca tgcaggagga
     3841 tgggttacta atgctctgcc gaattgccag caatgtcctc aacaccaagg tgaaaggacc
     3901 atttgtcacc tggcaggtcg tgcgtgacat tttgcatgct acctttgaag agtctttgga
     3961 taaaacatct cactcggttg gacgaagagc tcgctacata gtcaaaaatc cccaggcctt
     4021 tatgaactac aaagtctgcc tggcagaagt gtaccaagat aaggcactcg ttggagattt
     4081 catgagtcgg aaggataact acgaagaccc aaaggtctgt gccaaggagt ttaaagaatt
     4141 tgtggagaag ctgaaagaga agttcagctc tggcctgagg aaccccaacc ttgagatccc
     4201 agacacactg caggaactct ttgccaaata ccgggtgttg gcaatcggag atgaaaagga
     4261 ccgtgtcagg aaggaggatg aactgaatag tgtggaggac atccacttcc tggtgctaca
     4321 gaacctgatc cagagcacac tgtccctctc taacagccag tccaactctt gccagtcctt
     4381 ccagatcttc cgcctctacc gggagttccg ggagcctgtg ctggtgcggg ccttcatgga
     4441 gtgccaaaag aggagcctgg tcaaccgacg ccgtgtcagc cactcccagg gtcccaagaa
     4501 gaaccgtgct gtgccctttg tgcccatgtc ctaccagctc tcccagtcat actacaagct
     4561 tttcacctgg cgatttccca ccaccgtctg caccgaatcc ttccagttct atgacagact
     4621 acgggccaac ggcatactag accagcctga tcatttttct ttcaaggaca tggatagcaa
     4681 tgacccttca agtgacctgg tggcgttttc tttggacagc cctggaggac actgtgtgac
     4741 agccctggcc ctcttctcct tgggcctcct ctctgtggat gtccgaatcc cagagcagat
     4801 tgtggtggta gacagctcca tggtggagag tgaggtcatg aagagcttgg ggaaagatgg
     4861 cggcttggat gatgatgatg aggaggaaga cctggatgaa ggttcaggga ccaagcgtca
     4921 gagtgtggaa gtaaaggccc atcaggcctc acacaccaag tacctgctga tgagaggtta
     4981 ctacacagtg cctggcatgg tcagcacgcg caacctgaac cccaatgaca gcattgtggt
     5041 caattcctgc caggttaaat tccgactgcg caatacccct gcacccaccc atcttgggcc
     5101 cactgggccc acagccacac cgctagaaga gctccaggct ggcccttcct gcctccctgc
     5161 ctcctttacc agcctggtgg atccacagct gcacacccgc tgcccagaag agtttgccca
     5221 ccagatggca cagtctgggt acagccctga ggacgtggct gcgtccctag agatcctgca
     5281 ggctgtggca gctgctgact gcttcggggt tgacagggag aagctgagca gacagttctc
     5341 tgccttggag aagatagcgg acaagcgcac caggacgttc ctggactata tccaggacct
     5401 cttggaacag caacaagtca tggaagttgg aggcaacact gtgcgcctag tggccatggc
     5461 ctctgcccag ccctggctcc tgccttcagt gcgtctgaaa gatgtggaaa tagacaccaa
     5521 ggcctcaggg gatgacagcc aatctagact ccctgcgggg tcttccatcg aagaccacac
     5581 ctctgagggt gcaccaattc ctccagtcag ctccaatggc actaaaaagc gcccctactg
     5641 ctctattcag agccctgaaa ctgatgctga ggaagctaca aggctccctg ccaagaagcc
     5701 cacattacaa gatgtctgtg tggctgccag tcctaggcct ggaacagaag agcagacaga
     5761 ggcccaggct cagtttgcag ctcctgaaga tgcaggtgca gagggcccca ggcaggagag
     5821 ccaagagagt gttggtgtct caggcctaga gcagctgggc tgtgagttcc agcttccaga
     5881 aaattctgaa gaccccagag gacttacaga gagcaacatg gcccaggtag catgggagag
     5941 cggctgtgaa agagtatgtt ttgtcggtcg cccatggcgt ggtgtggacg ggcgcctgaa
     6001 catgcccgtg tgcaaaggca tgatggaagc cgtgctgtac cacatcatgt caaggcccgg
     6061 tgttcctgag agctgcctgc tacagtacta ccagggcgtc ctacagcctg ttgctgtgct
     6121 tgagctgctc cggggcttag agtctctcgg ctgtatccag aagcggatgc tgaagaagcc
     6181 agcgagtgtc tcactcttct ccaggcctgt ggtggagggc ctaggtcagg ccagtgaggc
     6241 cgaggcactc tcctgtcagg ggagcactgt caccttttat gaacctactc tggactgtac
     6301 catccgtctg ggccgtgtct tcccccatga catcaactgg aacaagtgga tccatttata
     6361 gatgcgtccc aggccagcag aggagcctct gcccgtgctt aattgttccg cctggactgt
     6421 cccaagagcc ccgtccttca cacagctgtt accagagctc ggcccagcct agcacaggtg
     6481 tagcaactag caggtgactt cagtcccctc tgctctcggc tgctcttggt cccaggtgcc
     6541 cagccttcct gcagccctgt gtcctgccct ggactcaggc tctagcatca gcagtatctg
     6601 caagggatgt tgtttaggga gcaggctgat gaccaagccc tgagtcacct cacacgcacc
     6661 acaccattca gactcagagg aagacacatc acaggtgtac ctggcagagt ctgctcctct
     6721 taaggtaggg catcccaact tggcctgaac tgagctcagg tctccagctc ccaaggggcc
     6781 cctcccgcca gaagcaaggc ctgtaggttt tgcttttgtt tttgttttat tttgcgctct
     6841 tttcactaga tacaagcccc tggcatgtat ttatttattt tttaattaaa gtaagatgaa
     6901 atgca
//
