LOCUS       NM_001001504            3110 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus GTF2I repeat domain containing 1 (Gtf2ird1),
            mRNA.
ACCESSION   NM_001001504 XM_341063 XM_347152
VERSION     NM_001001504.2
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3110)
  AUTHORS   Ganaie,I.A., Malik,M.Z., Naqvi,S.H., Jain,S.K. and Wajid,S.
  TITLE     Differential levels of Alpha-1-inhibitor III, Immunoglobulin heavy
            chain variable region, and Hypertrophied skeletal muscle protein
            GTF3 in rat mammary tumorigenesis
  JOURNAL   Biochimie 174, 57-68 (2020)
   PUBMED   32325114
  REMARK    GeneRIF: Differential levels of Alpha-1-inhibitor III,
            Immunoglobulin heavy chain variable region, and Hypertrophied
            skeletal muscle protein GTF3 in rat mammary tumorigenesis.
REFERENCE   2  (bases 1 to 3110)
  AUTHORS   Palmer,S.J., Taylor,K.M., Santucci,N., Widagdo,J., Chan,Y.K.,
            Yeo,J.L., Adams,M., Gunning,P.W. and Hardeman,E.C.
  TITLE     GTF2IRD2 from the Williams-Beuren critical region encodes a
            mobile-element-derived fusion protein that antagonizes the action
            of its related family members
  JOURNAL   J Cell Sci 125 (Pt 21), 5040-5050 (2012)
   PUBMED   22899722
REFERENCE   3  (bases 1 to 3110)
  AUTHORS   Enkhmandakh,B., Makeyev,A.V., Erdenechimeg,L., Ruddle,F.H.,
            Chimge,N.O., Tussie-Luna,M.I., Roy,A.L. and Bayarsaihan,D.
  TITLE     Essential functions of the Williams-Beuren syndrome-associated
            TFII-I genes in embryonic development
  JOURNAL   Proc Natl Acad Sci U S A 106 (1), 181-186 (2009)
   PUBMED   19109438
REFERENCE   4  (bases 1 to 3110)
  AUTHORS   Olofsson,P., Holmberg,J., Tordsson,J., Lu,S., Akerstrom,B. and
            Holmdahl,R.
  TITLE     Positional identification of Ncf1 as a gene that regulates
            arthritis severity in rats
  JOURNAL   Nat Genet 33 (1), 25-32 (2003)
   PUBMED   12461526
REFERENCE   5  (bases 1 to 3110)
  AUTHORS   Bayarsaihan,D. and Ruddle,F.H.
  TITLE     Isolation and characterization of BEN, a member of the TFII-I
            family of DNA-binding proteins containing distinct helix-loop-helix
            domains
  JOURNAL   Proc Natl Acad Sci U S A 97 (13), 7342-7347 (2000)
   PUBMED   10861001
REFERENCE   6  (bases 1 to 3110)
  AUTHORS   Franke,Y., Peoples,R.J. and Francke,U.
  TITLE     Identification of GTF2IRD1, a putative transcription factor within
            the Williams-Beuren syndrome deletion at 7q11.23
  JOURNAL   Cytogenet Cell Genet 86 (3-4), 296-304 (1999)
   PUBMED   10575229
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AF547389.1.
            
            [WARNING] On Mar 12, 2025 this sequence was replaced by
            NM_001001504.3.
            
            On Feb 21, 2013 this sequence version replaced NM_001001504.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AF547388.1, AF547389.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132262, SAMD00132264
                                           [ECO:0000348]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-3110              AF547389.1         1-3110
FEATURES             Location/Qualifiers
     source          1..3110
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="E3"
                     /db_xref="taxon:10116"
                     /chromosome="12"
                     /map="12q12"
     gene            1..3110
                     /gene="Gtf2ird1"
                     /gene_synonym="Gtf3"
                     /note="GTF2I repeat domain containing 1"
                     /db_xref="GeneID:246770"
                     /db_xref="RGD:620856"
     exon            1..141
                     /gene="Gtf2ird1"
                     /gene_synonym="Gtf3"
                     /inference="alignment:Splign:2.1.0"
     exon            142..270
                     /gene="Gtf2ird1"
                     /gene_synonym="Gtf3"
                     /inference="alignment:Splign:2.1.0"
     CDS             148..2979
                     /gene="Gtf2ird1"
                     /gene_synonym="Gtf3"
                     /note="general transcription factor II I repeat
                     domain-containing 1; general transcription factor II-I
                     repeat domain-containing protein 1-like"
                     /codon_start=1
                     /product="general transcription factor II-I repeat
                     domain-containing protein 1"
                     /protein_id="NP_001001504.1"
                     /db_xref="GeneID:246770"
                     /db_xref="RGD:620856"
                     /translation="MALLGKHCDIPTNGCGSERWNSTFARKDELINSLVSALDSMCSA
                     LSKLNTEVACVAVHNESVFVMGTEKGRVFLNTRKELQSDFLRFCRGPLWNDPEAGHPK
                     KVQRCEGGGRSIPRSSLEQCSDVYLLQKMVEEVFDVLYSEAMGRATVVPLPYERLLRE
                     PGLLAVQGLPEGLAFRRPAEYDPKALMAILEHSHRIRFKLRRPPDDGGQDTKALVEMN
                     GISLLPKGSRDCGLHGQASKVSPQDLTPTATPSSMANFLYSTSMPNHTIRELKQEVPT
                     CPLTPSDLGLGWPVPEPHVPSTQDFSDCCGQAPAGPAGPLIQNVHASKRILFSIVHDK
                     SEKWDPFIKEMEDINTLRECVQILFNSRYAEALGLDHMVPVPYRKIACDPEAVEIVGI
                     PDKIPFKRPCTYGVPKLKRILEERHSIHFIIKRMFDERIFTGNKFTKDPMKLEPASPP
                     EDTATEVCRDSMLDLAGTAWSDMSSVSEDCGPGTSGEIGMLRPIKIEPEELDIIQVTV
                     SDPSPTSEEMTDSLPGHLPSEDSGYGMEMPADKGPSEEPWQEERPAEESPGDVIRPLR
                     KQVEMLFNTKYAKAIGTSEPVKVPYSKFLMHPEELFVLGLPEGISLRRPNCFGIAKLR
                     KILEASNSIQFVIKRPELLTDGVKEPVMDTQERDSWDPLVDETPKRQGLQENYNTRLS
                     RIDIANTLREQVQDLFNKKYGEALGIKYPVQVPYKRIKSNPGSVIIEGLPPGIPFRKP
                     CTFGSQNLERILSVADKIKFTVTRPFQGLIPKPDEDDANRLGEKVILREQVKELFNEK
                     YGEALGLNRPVLVPYKLIRDSPDAVEVKGLPDDIPFRNPNTYDIHRLEKILKARDHVR
                     MVIINQLQPFGDVCNNAKVPAKDNIPKRKRKRVSEGNSVSSSSSSSSSSSSNPESVAS
                     TNQISLVQWPVYMVDYSGLNVQLPGPLDY"
     exon            271..412
                     /gene="Gtf2ird1"
                     /gene_synonym="Gtf3"
                     /inference="alignment:Splign:2.1.0"
     exon            413..568
                     /gene="Gtf2ird1"
                     /gene_synonym="Gtf3"
                     /inference="alignment:Splign:2.1.0"
     exon            569..752
                     /gene="Gtf2ird1"
                     /gene_synonym="Gtf3"
                     /inference="alignment:Splign:2.1.0"
     exon            753..1063
                     /gene="Gtf2ird1"
                     /gene_synonym="Gtf3"
                     /inference="alignment:Splign:2.1.0"
     exon            1064..1153
                     /gene="Gtf2ird1"
                     /gene_synonym="Gtf3"
                     /inference="alignment:Splign:2.1.0"
     exon            1154..1237
                     /gene="Gtf2ird1"
                     /gene_synonym="Gtf3"
                     /inference="alignment:Splign:2.1.0"
     exon            1238..1421
                     /gene="Gtf2ird1"
                     /gene_synonym="Gtf3"
                     /inference="alignment:Splign:2.1.0"
     exon            1422..1447
                     /gene="Gtf2ird1"
                     /gene_synonym="Gtf3"
                     /inference="alignment:Splign:2.1.0"
     exon            1448..1556
                     /gene="Gtf2ird1"
                     /gene_synonym="Gtf3"
                     /inference="alignment:Splign:2.1.0"
     exon            1557..1594
                     /gene="Gtf2ird1"
                     /gene_synonym="Gtf3"
                     /inference="alignment:Splign:2.1.0"
     exon            1595..1675
                     /gene="Gtf2ird1"
                     /gene_synonym="Gtf3"
                     /inference="alignment:Splign:2.1.0"
     exon            1676..1765
                     /gene="Gtf2ird1"
                     /gene_synonym="Gtf3"
                     /inference="alignment:Splign:2.1.0"
     exon            1766..1813
                     /gene="Gtf2ird1"
                     /gene_synonym="Gtf3"
                     /inference="alignment:Splign:2.1.0"
     exon            1814..1879
                     /gene="Gtf2ird1"
                     /gene_synonym="Gtf3"
                     /inference="alignment:Splign:2.1.0"
     exon            1880..2063
                     /gene="Gtf2ird1"
                     /gene_synonym="Gtf3"
                     /inference="alignment:Splign:2.1.0"
     exon            2064..2113
                     /gene="Gtf2ird1"
                     /gene_synonym="Gtf3"
                     /inference="alignment:Splign:2.1.0"
     exon            2114..2170
                     /gene="Gtf2ird1"
                     /gene_synonym="Gtf3"
                     /inference="alignment:Splign:2.1.0"
     exon            2171..2254
                     /gene="Gtf2ird1"
                     /gene_synonym="Gtf3"
                     /inference="alignment:Splign:2.1.0"
     exon            2255..2438
                     /gene="Gtf2ird1"
                     /gene_synonym="Gtf3"
                     /inference="alignment:Splign:2.1.0"
     exon            2439..2467
                     /gene="Gtf2ird1"
                     /gene_synonym="Gtf3"
                     /inference="alignment:Splign:2.1.0"
     exon            2468..2545
                     /gene="Gtf2ird1"
                     /gene_synonym="Gtf3"
                     /inference="alignment:Splign:2.1.0"
     exon            2546..2738
                     /gene="Gtf2ird1"
                     /gene_synonym="Gtf3"
                     /inference="alignment:Splign:2.1.0"
     exon            2739..2776
                     /gene="Gtf2ird1"
                     /gene_synonym="Gtf3"
                     /inference="alignment:Splign:2.1.0"
     exon            2777..2910
                     /gene="Gtf2ird1"
                     /gene_synonym="Gtf3"
                     /inference="alignment:Splign:2.1.0"
     exon            2911..3110
                     /gene="Gtf2ird1"
                     /gene_synonym="Gtf3"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gccctccttc cctccctccc tctactgatc ctgtccccca ctcccggatt attaactcag
       61 caaccagagg cgactggatc taccgagtcc tggccaccgg gcccgggccg gggcgcccgg
      121 agcgcttggg gatcctgcaa ggtgaccatg gccttgctgg ggaagcattg tgacatcccc
      181 accaacggct gtgggtctga gcgctggaac tccacctttg cccgcaagga cgagctcatc
      241 aacagtctgg tgtctgcctt agactccatg tgctcagcgc tctccaagct gaacacagag
      301 gtggcctgcg tggcggtaca caatgagagc gtcttcgtga tgggcaccga gaagggaagg
      361 gtgtttttga atactcggaa ggagctacag tcagacttcc tcaggttctg ccggggaccc
      421 ctgtggaacg atccagaagc aggacaccct aaaaaggtgc agcgctgcga aggtggtggc
      481 cggagcatcc cgcggtcctc tctggagcag tgctcggatg tgtacctgct gcagaagatg
      541 gtagaggaag tgtttgatgt tctttatagt gaggctatgg gcagggccac cgtggtacct
      601 ttgccctatg agaggctgct cagggagccg gggctactgg cggtgcaagg gctgcccgag
      661 ggcctggcct tccggagacc agcagaatat gaccccaagg cactcatggc cattttggag
      721 catagtcacc gaattcggtt taagctcagg aggcctcctg atgacggtgg gcaggacaca
      781 aaggcgctgg tggagatgaa cggtatctct ctgctaccca aggggtcccg agactgtggt
      841 ctgcatggcc aggcctccaa ggtctctccc caagacctga cccccaccgc caccccatcc
      901 tccatggcca acttcctgta cagcacttcg atgcccaacc acaccatccg ggaactcaag
      961 caggaggtgc caacctgccc gttgaccccc agcgacctgg gcttgggctg gcctgtgcct
     1021 gagccccatg tccccagcac ccaagatttc tctgattgct gtggacaggc gcctgcaggg
     1081 cctgctgggc ctctcatcca gaatgtccac gcttccaagc gtatcctctt ctccatcgtc
     1141 cacgacaagt cagagaagtg ggatcccttc atcaaggaaa tggaggacat caacaccctg
     1201 cgggagtgcg tgcagattct gtttaacagc agatacgcgg aagccctggg cctggaccat
     1261 atggttcctg tgccctacag gaagattgcc tgtgaccctg aggctgtgga gattgtgggt
     1321 atcccagaca agatcccctt caagcggccc tgcacttatg gagtgccgaa gctgaagaga
     1381 attctggagg agcggcacag cattcacttc attatcaaga ggatgttcga tgagcgcatt
     1441 ttcacaggga acaagtttac caaagacccc atgaagctgg agccagctag cccaccagaa
     1501 gacactgcca cagaagtctg tagggacagc atgctggacc tggctgggac tgcttggtca
     1561 gacatgagca gcgtctctga agactgtggg ccaggaacct caggagagat aggaatgttg
     1621 aggcctatca aaatcgagcc cgaggagctg gacattattc aggttactgt ctcagatcct
     1681 tcacctacct ctgaggagat gactgactca ctacctgggc atctaccctc agaagattcc
     1741 ggttatggga tggaaatgcc ggctgacaaa ggccccagtg aggaaccgtg gcaagaagag
     1801 aggccggcag aagagagccc tggtgatgtg atcaggcccc tccggaagca ggtggaaatg
     1861 ctgttcaaca caaaatatgc caaagccatt ggtacctcag agccagtcaa ggtgccctac
     1921 tccaagttcc tgatgcaccc ggaggagctc ttcgtactgg gactgcctga aggcatctct
     1981 cttcgaagac ccaactgctt tgggattgcc aagctgagga agattctgga agccagcaac
     2041 agtatccagt ttgtcattaa gagacccgaa ctactcactg acggtgtcaa agaacctgtt
     2101 atggacactc aagagaggga ctcctgggac cctcttgtgg acgagacccc gaagagacag
     2161 ggccttcaag aaaattacaa caccagactc tctcggatcg acatcgccaa cacgcttagg
     2221 gaacaagtcc aagacctgtt taacaagaaa tacggtgaag ctctgggcat caaataccca
     2281 gtgcaggtgc cctacaagcg aatcaaaagc aatccaggct cggtaatcat cgaaggcctg
     2341 ccccccggga tcccattccg caagccctgc acctttggct cccagaacct ggaaaggatc
     2401 ctctctgtgg ctgacaagat caagttcacc gtcaccaggc catttcaagg actcatccca
     2461 aagcctgatg aggatgatgc caacagactg ggggagaagg tgatcctccg agagcaggtg
     2521 aaggagctct tcaatgagaa atacggtgag gccctgggac tgaatcggcc tgtgctggtc
     2581 ccgtacaagc tgatccggga cagcccggat gccgtggagg tgaaaggcct cccagatgac
     2641 atccccttcc ggaaccccaa cacctacgac atccatcggc tggagaagat cctgaaggcc
     2701 agagaccacg tacggatggt tatcatcaac cagctccaac cttttgggga tgtctgcaac
     2761 aatgccaagg tgccagccaa agacaacatt cccaagcgca agagaaagcg ggtctctgaa
     2821 ggcaactcag tctcctcctc ttcctcttct tcatcctcct cgtcctctaa tccagagtct
     2881 gtggcgtcca ccaaccagat ctccctcgtg cagtggccag tgtacatggt ggactattcc
     2941 ggactaaacg tgcagcttcc aggccccctt gattattaga cctcagagcc gaatcaggac
     3001 ctcaactcaa aagactaaag gaaaatgtaa tttatgtaca aagtatattc ggatatgtat
     3061 cgatgccttt tagtttttcc aatgattttt acactatatt cctgccgcca
//
