LOCUS       NP_001019407             309 aa            linear   ROD 03-APR-2024
DEFINITION  general transcription factor IIH subunit 3 [Rattus norvegicus].
ACCESSION   NP_001019407 XP_213778
VERSION     NP_001019407.1
DBSOURCE    REFSEQ: accession NM_001024236.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (residues 1 to 309)
  AUTHORS   He,Y., Yan,C., Fang,J., Inouye,C., Tjian,R., Ivanov,I. and
            Nogales,E.
  TITLE     Near-atomic resolution visualization of human transcription
            promoter opening
  JOURNAL   Nature 533 (7603), 359-365 (2016)
   PUBMED   27193682
REFERENCE   2  (residues 1 to 309)
  AUTHORS   Egly,J.M. and Coin,F.
  TITLE     A history of TFIIH: two decades of molecular biology on a pivotal
            transcription/repair factor
  JOURNAL   DNA Repair (Amst) 10 (7), 714-721 (2011)
   PUBMED   21592869
  REMARK    Review article
REFERENCE   3  (residues 1 to 309)
  AUTHORS   Kershnar,E., Wu,S.Y. and Chiang,C.M.
  TITLE     Immunoaffinity purification and functional characterization of
            human transcription factor IIH and RNA polymerase II from clonal
            cell lines that conditionally express epitope-tagged subunits of
            the multiprotein complexes
  JOURNAL   J Biol Chem 273 (51), 34444-34453 (1998)
   PUBMED   9852112
REFERENCE   4  (residues 1 to 309)
  AUTHORS   Iyer,N., Reagan,M.S., Wu,K.J., Canagarajah,B. and Friedberg,E.C.
  TITLE     Interactions involving the human RNA polymerase II
            transcription/nucleotide excision repair complex TFIIH, the
            nucleotide excision repair protein XPG, and Cockayne syndrome group
            B (CSB) protein
  JOURNAL   Biochemistry 35 (7), 2157-2167 (1996)
   PUBMED   8652557
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC093380.1.
            
            On May 27, 2005 this sequence version replaced XP_213778.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC093380.1, SRR8487230.117016.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMD00132261,
                                           SAMD00132262 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..309
                     /organism="Rattus norvegicus"
                     /db_xref="taxon:10116"
                     /chromosome="12"
                     /map="12q15"
     Protein         1..309
                     /product="general transcription factor IIH subunit 3"
                     /note="general transcription factor IIH, polypeptide 3"
                     /calculated_mol_wt=34147
     Region          7..290
                     /region_name="tfb4"
                     /note="transcription factor tfb4; TIGR00627"
                     /db_xref="CDD:273181"
     CDS             1..309
                     /gene="Gtf2h3"
                     /coded_by="NM_001024236.1:25..954"
                     /db_xref="GeneID:288651"
                     /db_xref="RGD:1305494"
ORIGIN      
        1 maadedelnl lviivdtnpi wwgkqalkes qftlskcmda vmvlanahlf mnrsnqlavi
       61 ashiqesrfl ypgkngrlgd ffgdpgnalp dcnpsgskdg kyelltaane viaeeikdlm
      121 tksdikgqht etllagslak alcyihrask avkdnqemks rilvikaaed salqymnfmn
      181 vifaaqkqni lidacvldsd sgllqqacdi tgglylkvpq mpsllqyllw vflpdqdqrs
      241 qlilpppihv dyraacfchr slieigyvcs vclsifcnfs picttcetaf kislppvlka
      301 kkkkqkvsl
//
