LOCUS       NM_001077428            1394 bp    mRNA    linear   ROD 02-JUN-2024
DEFINITION  Rattus norvegicus general transcription factor IIH subunit 2
            (Gtf2h2), mRNA.
ACCESSION   NM_001077428 XM_001062050 XM_215466
VERSION     NM_001077428.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1394)
  AUTHORS   Melis,J.P., Luijten,M., Mullenders,L.H. and van Steeg,H.
  TITLE     The role of XPC: implications in cancer and oxidative DNA damage
  JOURNAL   Mutat Res 728 (3), 107-117 (2011)
   PUBMED   21763452
REFERENCE   2  (bases 1 to 1394)
  AUTHORS   Egly,J.M. and Coin,F.
  TITLE     A history of TFIIH: two decades of molecular biology on a pivotal
            transcription/repair factor
  JOURNAL   DNA Repair (Amst) 10 (7), 714-721 (2011)
   PUBMED   21592869
  REMARK    Review article
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC126097.1.
            
            On or before Oct 29, 2006 this sequence version replaced
            XM_215466.4, XM_001062050.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC126097.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMD00132261,
                                           SAMD00132262 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1394
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="2"
                     /map="2q12"
     gene            1..1394
                     /gene="Gtf2h2"
                     /gene_synonym="BTF2 p44"
                     /note="general transcription factor IIH subunit 2"
                     /db_xref="GeneID:294693"
                     /db_xref="RGD:1310499"
     exon            1..30
                     /gene="Gtf2h2"
                     /gene_synonym="BTF2 p44"
                     /inference="alignment:Splign:2.1.0"
     exon            31..119
                     /gene="Gtf2h2"
                     /gene_synonym="BTF2 p44"
                     /inference="alignment:Splign:2.1.0"
     CDS             64..1254
                     /gene="Gtf2h2"
                     /gene_synonym="BTF2 p44"
                     /note="BTF2-p44; basic transcription factor 2 44 kDa
                     subunit; TFIIH basal transcription factor complex p44
                     subunit; general transcription factor IIH, polypeptide 2"
                     /codon_start=1
                     /product="general transcription factor IIH subunit 2"
                     /protein_id="NP_001070896.1"
                     /db_xref="GeneID:294693"
                     /db_xref="RGD:1310499"
                     /translation="MDEEPERTKRWEGGYERTWEILKEDESGSLKATIEDILFKAKRK
                     RVFEHHGQVRLGMMRHLYVVVDGSRTMEDQDLKPNRLTCTLKLLEYFVEEYFDQNPIS
                     QIGIIVTKSKRAEKLTELSGNPRKHITSLKKAVDMTCHGEPSLYNSLSMAMQTLKHMP
                     GHTSREVLIIFSSLTTCDPSNIYDLIKTLKTAKIRVSVIGLSAEVRVCTVLARETGGT
                     YHVILDETHYKELLARHVSPPPASSGSECSLIRMGFPQHTIASLSDQDAKPSFSMAHL
                     DNNSTEPGLTLGGYFCPQCRAKYCELPVECKICGLTLVSAPHLARSYHHLFPLDAFQE
                     IPLEEYKGERFCYGCQGELKDQHVYVCTVCRNVFCVDCDVFVHDSLHCCPGCVHKIPT
                     QSGV"
     exon            120..197
                     /gene="Gtf2h2"
                     /gene_synonym="BTF2 p44"
                     /inference="alignment:Splign:2.1.0"
     exon            198..234
                     /gene="Gtf2h2"
                     /gene_synonym="BTF2 p44"
                     /inference="alignment:Splign:2.1.0"
     exon            235..321
                     /gene="Gtf2h2"
                     /gene_synonym="BTF2 p44"
                     /inference="alignment:Splign:2.1.0"
     exon            322..372
                     /gene="Gtf2h2"
                     /gene_synonym="BTF2 p44"
                     /inference="alignment:Splign:2.1.0"
     exon            373..427
                     /gene="Gtf2h2"
                     /gene_synonym="BTF2 p44"
                     /inference="alignment:Splign:2.1.0"
     exon            428..533
                     /gene="Gtf2h2"
                     /gene_synonym="BTF2 p44"
                     /inference="alignment:Splign:2.1.0"
     exon            534..624
                     /gene="Gtf2h2"
                     /gene_synonym="BTF2 p44"
                     /inference="alignment:Splign:2.1.0"
     exon            625..712
                     /gene="Gtf2h2"
                     /gene_synonym="BTF2 p44"
                     /inference="alignment:Splign:2.1.0"
     exon            713..820
                     /gene="Gtf2h2"
                     /gene_synonym="BTF2 p44"
                     /inference="alignment:Splign:2.1.0"
     exon            821..884
                     /gene="Gtf2h2"
                     /gene_synonym="BTF2 p44"
                     /inference="alignment:Splign:2.1.0"
     exon            885..991
                     /gene="Gtf2h2"
                     /gene_synonym="BTF2 p44"
                     /inference="alignment:Splign:2.1.0"
     exon            992..1094
                     /gene="Gtf2h2"
                     /gene_synonym="BTF2 p44"
                     /inference="alignment:Splign:2.1.0"
     exon            1095..1134
                     /gene="Gtf2h2"
                     /gene_synonym="BTF2 p44"
                     /inference="alignment:Splign:2.1.0"
     exon            1135..1371
                     /gene="Gtf2h2"
                     /gene_synonym="BTF2 p44"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cttccggtga gggtcttcta gtcgaggccg tgttgaataa gcatatatat aattataaaa
       61 accatggatg aagaacctga aagaactaag cggtgggaag gaggctatga gagaacctgg
      121 gaaattctta aagaagatga aagtggatca cttaaagcta caatagagga tattctcttc
      181 aaggcaaaga ggaaaagagt gtttgagcac catggacaag ttcgacttgg aatgatgcgc
      241 cacctgtacg tggtggtgga tgggtccaga acaatggaag atcaggattt aaagcccaac
      301 agactgacct gtactctaaa gttgttggaa tattttgtag aagaatattt tgatcaaaac
      361 cctatcagtc agattggcat aattgtaact aagagtaaaa gagctgaaaa actgactgaa
      421 ctctcaggaa acccaaggaa acacataaca tctttgaaga aagctgtaga tatgacctgc
      481 catggagaac catcactcta taattcctta agcatggcta tgcaaaccct aaaacacatg
      541 cccggacaca caagcagaga agtgctcatc atcttcagca gcctcacgac ctgtgacccc
      601 tctaatattt atgacctcat caagaccctg aagacagcta aaattagagt gtctgttatt
      661 gggttgtctg cggaggttcg agtttgtact gtacttgctc gagaaactgg tggcacatac
      721 cacgtcatcc tagatgagac ccattacaag gagctgttag cccgtcatgt gagccctcct
      781 cccgccagct ccggctccga gtgctccctt atccgcatgg gattccctca gcataccatt
      841 gcctctctgt ctgatcagga tgcaaaacca tccttcagca tggcgcattt ggataataat
      901 agcactgaac cagggcttac attgggaggc tatttctgcc cacagtgtcg agcaaagtac
      961 tgtgagcttc ctgtcgaatg taaaatatgt ggtcttactt tggtgtctgc acctcacttg
     1021 gcaagatctt atcatcattt atttcctttg gatgcttttc aagaaatccc cctggaagaa
     1081 tataaaggag agaggttttg ttatggatgt cagggtgaat tgaaagacca acatgtctat
     1141 gtttgcacag tgtgccggaa cgtcttctgt gtggactgcg atgtctttgt tcacgactct
     1201 ctccactgct gtcctggctg tgttcataag atcccaactc agtcaggtgt ttgatcccac
     1261 gaagaacaca cacattgagt aggttaaaaa cagaacaaag cttgtgactg taaataaaat
     1321 gactttgaat aaactgattc tctaattaaa gcatgaaaac atttgaaaga aaaaaaaaaa
     1381 aaaaaaaaaa aaaa
//
