LOCUS       NM_031042               1481 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus general transcription factor IIF subunit 2
            (Gtf2f2), mRNA.
ACCESSION   NM_031042
VERSION     NM_031042.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1481)
  AUTHORS   Grunberg,S. and Hahn,S.
  TITLE     Structural insights into transcription initiation by RNA polymerase
            II
  JOURNAL   Trends Biochem Sci 38 (12), 603-611 (2013)
   PUBMED   24120742
  REMARK    Review article
REFERENCE   2  (bases 1 to 1481)
  AUTHORS   Kwak,H. and Lis,J.T.
  TITLE     Control of transcriptional elongation
  JOURNAL   Annu Rev Genet 47, 483-508 (2013)
   PUBMED   24050178
  REMARK    Review article
REFERENCE   3  (bases 1 to 1481)
  AUTHORS   Sigal,A., Milo,R., Cohen,A., Geva-Zatorsky,N., Klein,Y., Alaluf,I.,
            Swerdlin,N., Perzov,N., Danon,T., Liron,Y., Raveh,T.,
            Carpenter,A.E., Lahav,G. and Alon,U.
  TITLE     Dynamic proteomics in individual human cells uncovers widespread
            cell-cycle dependence of nuclear proteins
  JOURNAL   Nat Methods 3 (7), 525-531 (2006)
   PUBMED   16791210
REFERENCE   4  (bases 1 to 1481)
  AUTHORS   Sabbah,M., Kang,K.I., Tora,L. and Redeuilh,G.
  TITLE     Oestrogen receptor facilitates the formation of preinitiation
            complex assembly: involvement of the general transcription factor
            TFIIB
  JOURNAL   Biochem J 336 (Pt 3) (Pt 3), 639-646 (1998)
   PUBMED   9841876
REFERENCE   5  (bases 1 to 1481)
  AUTHORS   Fang,S.M. and Burton,Z.F.
  TITLE     RNA polymerase II-associated protein (RAP) 74 binds transcription
            factor (TF) IIB and blocks TFIIB-RAP30 binding
  JOURNAL   J Biol Chem 271 (20), 11703-11709 (1996)
   PUBMED   8662660
REFERENCE   6  (bases 1 to 1481)
  AUTHORS   Ossipow,V., Tassan,J.P., Nigg,E.A. and Schibler,U.
  TITLE     A mammalian RNA polymerase II holoenzyme containing all components
            required for promoter-specific transcription initiation
  JOURNAL   Cell 83 (1), 137-146 (1995)
   PUBMED   7553866
REFERENCE   7  (bases 1 to 1481)
  AUTHORS   Tan,S., Aso,T., Conaway,R.C. and Conaway,J.W.
  TITLE     Roles for both the RAP30 and RAP74 subunits of transcription factor
            IIF in transcription initiation and elongation by RNA polymerase II
  JOURNAL   J Biol Chem 269 (41), 25684-25691 (1994)
   PUBMED   7929273
REFERENCE   8  (bases 1 to 1481)
  AUTHORS   Garrett,K.P., Serizawa,H., Hanley,J.P., Bradsher,J.N., Tsuboi,A.,
            Arai,N., Yokota,T., Arai,K., Conaway,R.C. and Conaway,J.W.
  TITLE     The carboxyl terminus of RAP30 is similar in sequence to region 4
            of bacterial sigma factors and is required for function
  JOURNAL   J Biol Chem 267 (33), 23942-23949 (1992)
   PUBMED   1429731
REFERENCE   9  (bases 1 to 1481)
  AUTHORS   Kobayashi,Y., Kitajima,S. and Yasukochi,Y.
  TITLE     Isolation and nucleotide sequence of a rat cDNA homologous to human
            RAP30
  JOURNAL   Nucleic Acids Res 20 (8), 1994 (1992)
   PUBMED   1579505
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC091112.1.
            
            On Mar 27, 2005 this sequence version replaced NM_031042.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC091112.1, FQ232071.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMD00132261,
                                           SAMD00132262 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1481
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="15"
                     /map="15q11"
     gene            1..1481
                     /gene="Gtf2f2"
                     /gene_synonym="Rap30"
                     /note="general transcription factor IIF subunit 2"
                     /db_xref="GeneID:81674"
                     /db_xref="RGD:620772"
     exon            1..178
                     /gene="Gtf2f2"
                     /gene_synonym="Rap30"
                     /inference="alignment:Splign:2.1.0"
     CDS             113..862
                     /gene="Gtf2f2"
                     /gene_synonym="Rap30"
                     /EC_number="3.6.4.12"
                     /note="TFIIF-beta; ATP-dependent helicase GTF2F2;
                     transcription initiation factor RAP30; transcription
                     initiation factor IIF subunit beta; general transcription
                     factor IIF, polypeptide 2 (30kD subunit); transcription
                     factor gamma"
                     /codon_start=1
                     /product="general transcription factor IIF subunit 2"
                     /protein_id="NP_112304.2"
                     /db_xref="GeneID:81674"
                     /db_xref="RGD:620772"
                     /translation="MAERGELDLTGAKQNTGVWLVKVPKYLSQQWAKAPGRGEVGKLR
                     IAKNQGRTEVSFTLNEDLANIHDIGGKPASVSAPREHPFVLQSVGGQTLTVFTESSSD
                     KLSLEGIVVQRAECRPAASENYMKLKRLQIEESSKPVRLSQQLDKVVTTNYKPVANHQ
                     YNIEYERKKKEDGKRARADKQHVLDMLFSAFEKHQYYNLKDLVDITKQPVGYLKEILK
                     EIGIQNVKGIHKNTWELKPEYRHYQTEEKSD"
     exon            179..252
                     /gene="Gtf2f2"
                     /gene_synonym="Rap30"
                     /inference="alignment:Splign:2.1.0"
     exon            253..271
                     /gene="Gtf2f2"
                     /gene_synonym="Rap30"
                     /inference="alignment:Splign:2.1.0"
     exon            272..416
                     /gene="Gtf2f2"
                     /gene_synonym="Rap30"
                     /inference="alignment:Splign:2.1.0"
     exon            417..498
                     /gene="Gtf2f2"
                     /gene_synonym="Rap30"
                     /inference="alignment:Splign:2.1.0"
     exon            499..598
                     /gene="Gtf2f2"
                     /gene_synonym="Rap30"
                     /inference="alignment:Splign:2.1.0"
     exon            599..742
                     /gene="Gtf2f2"
                     /gene_synonym="Rap30"
                     /inference="alignment:Splign:2.1.0"
     exon            743..1450
                     /gene="Gtf2f2"
                     /gene_synonym="Rap30"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggcttttcgc ggtctacttg tcccagcgtc cggctctgga ctgtctatcg ctctctgacg
       61 ttcagtcccg ggtcgctgct tgtgcgcgca cgccgcctca cacgacaaac ttatggcgga
      121 gcgcggggaa ctcgatctga cgggcgccaa acagaacacc ggcgtgtggc tggtgaaggt
      181 tcctaaatat ttgtcccagc aatgggcaaa agcccctgga agaggtgaag ttgggaaact
      241 gaggattgcc aagaatcaag gaaggactga ggtatcattt actttgaatg aggatcttgc
      301 gaatattcat gatatcggtg ggaaaccagc ttcagtcagt gctcctagag aacatccatt
      361 tgtcttgcaa agtgttggag gacagacatt aacagtgttc accgagagct cctcagataa
      421 actgtcattg gaaggaatag tggttcagag agcggaatgc cgacctgctg ccagtgaaaa
      481 ctacatgaaa ctaaagagat tgcaaataga agaatcttcc aaacctgtaa ggctctcaca
      541 acagctggac aaagttgtaa ccaccaatta caagcctgtc gctaaccatc agtacaatat
      601 tgaatatgaa aggaagaaga aagaagatgg aaagcgagct cgggcagaca aacaacacgt
      661 cctagacatg ctgttctcag cctttgagaa acatcagtac tataatctta aggacttggt
      721 ggacatcaca aagcaacctg tgggatacct gaaagaaatc ttgaaagaaa tcggcattca
      781 gaatgtaaaa ggaattcaca agaatacgtg ggagctgaag ccagagtaca ggcattacca
      841 aacagaggag aagagcgact gagagaagcg tgtgcaacag ttacaggcag atctctgcca
      901 ccacacgctg actgcctgcc caccctgaca ggacaaagac aactgagtct gtctgccatt
      961 cctcagtaaa ctgttaaagc tgggactcca aaaggtttct aagtgttttt tgaagagaaa
     1021 gatattattt atagactaga cttgtgttaa gccatagcat tcagcaggca tgctgacaac
     1081 acatacatgt gtctgacact caggagactg aggcaggcaa agggtgagtg actttgagac
     1141 cagtctggaa tacacagcaa gaccctctcc cataaaagga aaacattaca gtatgggtag
     1201 ggtctggggt tacaactgcc tctgttccca ctggttagct ttgcaagtgt aaatgggaca
     1261 tttcctaaat gaaattgtat ctctgaggaa ctaaggtaag aatggagaaa gtggggggag
     1321 ggaaactatt aaaggaacag agttgaagtt cctttttctg aaactgaaga gggaacttgt
     1381 ccctccctac agaggtaata ttttaccttc aaacatacgt aaataaagag atctgttccc
     1441 tttgtactaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa a
//
