LOCUS       NM_001007711            1706 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus general transcription factor IIF subunit 1
            (Gtf2f1), mRNA.
ACCESSION   NM_001007711 XM_236789
VERSION     NM_001007711.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1706)
  AUTHORS   He,Y., Yan,C., Fang,J., Inouye,C., Tjian,R., Ivanov,I. and
            Nogales,E.
  TITLE     Near-atomic resolution visualization of human transcription
            promoter opening
  JOURNAL   Nature 533 (7603), 359-365 (2016)
   PUBMED   27193682
REFERENCE   2  (bases 1 to 1706)
  AUTHORS   Gelev,V., Zabolotny,J.M., Lange,M., Hiromura,M., Yoo,S.W.,
            Orlando,J.S., Kushnir,A., Horikoshi,N., Paquet,E., Bachvarov,D.,
            Schaffer,P.A. and Usheva,A.
  TITLE     A new paradigm for transcription factor TFIIB functionality
  JOURNAL   Sci Rep 4, 3664 (2014)
   PUBMED   24441171
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1706)
  AUTHORS   Grunberg,S. and Hahn,S.
  TITLE     Structural insights into transcription initiation by RNA polymerase
            II
  JOURNAL   Trends Biochem Sci 38 (12), 603-611 (2013)
   PUBMED   24120742
  REMARK    Review article
REFERENCE   4  (bases 1 to 1706)
  AUTHORS   Kwak,H. and Lis,J.T.
  TITLE     Control of transcriptional elongation
  JOURNAL   Annu Rev Genet 47, 483-508 (2013)
   PUBMED   24050178
  REMARK    Review article
REFERENCE   5  (bases 1 to 1706)
  AUTHORS   Baltz,A.G., Munschauer,M., Schwanhausser,B., Vasile,A.,
            Murakawa,Y., Schueler,M., Youngs,N., Penfold-Brown,D., Drew,K.,
            Milek,M., Wyler,E., Bonneau,R., Selbach,M., Dieterich,C. and
            Landthaler,M.
  TITLE     The mRNA-bound proteome and its global occupancy profile on
            protein-coding transcripts
  JOURNAL   Mol Cell 46 (5), 674-690 (2012)
   PUBMED   22681889
REFERENCE   6  (bases 1 to 1706)
  AUTHORS   Newberry,E.P., Latifi,T., Battaile,J.T. and Towler,D.A.
  TITLE     Structure-function analysis of Msx2-mediated transcriptional
            suppression
  JOURNAL   Biochemistry 36 (34), 10451-10462 (1997)
   PUBMED   9265625
REFERENCE   7  (bases 1 to 1706)
  AUTHORS   Fang,S.M. and Burton,Z.F.
  TITLE     RNA polymerase II-associated protein (RAP) 74 binds transcription
            factor (TF) IIB and blocks TFIIB-RAP30 binding
  JOURNAL   J Biol Chem 271 (20), 11703-11709 (1996)
   PUBMED   8662660
REFERENCE   8  (bases 1 to 1706)
  AUTHORS   Dikstein,R., Ruppert,S. and Tjian,R.
  TITLE     TAFII250 is a bipartite protein kinase that phosphorylates the base
            transcription factor RAP74
  JOURNAL   Cell 84 (5), 781-790 (1996)
   PUBMED   8625415
REFERENCE   9  (bases 1 to 1706)
  AUTHORS   Garrett,K.P., Serizawa,H., Hanley,J.P., Bradsher,J.N., Tsuboi,A.,
            Arai,N., Yokota,T., Arai,K., Conaway,R.C. and Conaway,J.W.
  TITLE     The carboxyl terminus of RAP30 is similar in sequence to region 4
            of bacterial sigma factors and is required for function
  JOURNAL   J Biol Chem 267 (33), 23942-23949 (1992)
   PUBMED   1429731
REFERENCE   10 (bases 1 to 1706)
  AUTHORS   Finkelstein,A., Kostrub,C.F., Li,J., Chavez,D.P., Wang,B.Q.,
            Fang,S.M., Greenblatt,J. and Burton,Z.F.
  TITLE     A cDNA encoding RAP74, a general initiation factor for
            transcription by RNA polymerase II
  JOURNAL   Nature 355 (6359), 464-467 (1992)
   PUBMED   1734284
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC079136.1.
            
            On Nov 29, 2004 this sequence version replaced XM_236789.2.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC079136.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760389, SAMN06680448
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1706
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="9"
                     /map="9q11"
     gene            1..1706
                     /gene="Gtf2f1"
                     /note="general transcription factor IIF subunit 1"
                     /db_xref="GeneID:316123"
                     /db_xref="RGD:1359646"
     exon            1..138
                     /gene="Gtf2f1"
                     /inference="alignment:Splign:2.1.0"
     CDS             127..1653
                     /gene="Gtf2f1"
                     /note="TFIIF-alpha; transcription initiation factor IIF
                     subunit alpha; general transcription factor IIF,
                     polypeptide 1, 74kDa"
                     /codon_start=1
                     /product="general transcription factor IIF subunit 1"
                     /protein_id="NP_001007712.1"
                     /db_xref="GeneID:316123"
                     /db_xref="RGD:1359646"
                     /translation="MAALGSSSQNVTEYVVRVPKNTAKRYNIMAFNAADKVNFATWNQ
                     ARLERDLSNKKIYQEEEMPESGAGSEFNRKLREEARRKKYGIVLKEFRPEDQPWLLRV
                     NGKSGRKFKGIKKGGVTENTAYYIFTQCADGAFEAFPVQNWYNFTPLARHRTLTAEEA
                     EEEWERRNKVLNHFSIMQQRRLKDQDQDEDEEEKEKRSRKKPSELRIHDLEDDLEMSS
                     DASDASGEEGSRASKAKKKAPVTKAGRKKKKKKGSDDEAFEDSDDGDFEGQEVDYMSD
                     GSSSSPDEAEGKPKVPQQEDGPKGVDEQSESSEESEEEKPPEEDKEEEEEKKAPTPQE
                     KKRRKDSSDDSDSSEESDIDSETSSALFMAKKKTPPKRERKPSGGSSKGTSRPGTPSA
                     EAASTSSTLRAAASKLEQGKRTSETPAAKRLRMDTGPQSLSGKSTPSSGDVQVTEDAV
                     RRYLTRKPMTTKDLLKKFQTKKTGLSSEQTVNVLAQILKRLNPERKMIGDKMHFSLKE
                     "
     exon            139..185
                     /gene="Gtf2f1"
                     /inference="alignment:Splign:2.1.0"
     exon            186..258
                     /gene="Gtf2f1"
                     /inference="alignment:Splign:2.1.0"
     exon            259..452
                     /gene="Gtf2f1"
                     /inference="alignment:Splign:2.1.0"
     exon            453..623
                     /gene="Gtf2f1"
                     /inference="alignment:Splign:2.1.0"
     exon            624..808
                     /gene="Gtf2f1"
                     /inference="alignment:Splign:2.1.0"
     exon            809..962
                     /gene="Gtf2f1"
                     /inference="alignment:Splign:2.1.0"
     exon            963..1024
                     /gene="Gtf2f1"
                     /inference="alignment:Splign:2.1.0"
     exon            1025..1144
                     /gene="Gtf2f1"
                     /inference="alignment:Splign:2.1.0"
     exon            1145..1218
                     /gene="Gtf2f1"
                     /inference="alignment:Splign:2.1.0"
     exon            1219..1357
                     /gene="Gtf2f1"
                     /inference="alignment:Splign:2.1.0"
     exon            1358..1448
                     /gene="Gtf2f1"
                     /inference="alignment:Splign:2.1.0"
     exon            1449..1676
                     /gene="Gtf2f1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggtttggaaa tccaaagcac aggatcacac taacgtgaca accaggaaag gtgctttccc
       61 tgggtccgag ggacacaacc aagaccatcc aggtctggcc gacccggagc agcttgagca
      121 acggccatgg cggctctagg ctccagcagc cagaatgtca ctgagtacgt cgtccgagtc
      181 cccaagaaca cagccaaaag atacaacata atggctttta atgcagctga taaagtcaac
      241 tttgctacct ggaaccaggc acggctggag cgagatctga gcaacaagaa gatctaccag
      301 gaagaggaga tgccagagtc tggtgcagga agtgaattca accgcaagct cagggaggag
      361 gctcgccgga agaagtatgg catcgtcctg aaggagttcc ggcctgagga ccagccctgg
      421 ctactccgtg tcaatggcaa atcggggagg aagttcaagg gcatcaagaa aggcggggta
      481 acagagaaca cggcctacta catcttcaca cagtgtgcgg atggcgcctt cgaggccttc
      541 cctgtgcaga actggtacaa tttcacaccg ctggcccgac accgcacact gactgctgag
      601 gaagctgagg aggaatggga gaggaggaac aaggtcctga accacttcag catcatgcag
      661 cagcggcgac tcaaggacca ggaccaggat gaagatgagg aggagaagga gaagcgcagc
      721 cgtaagaagc ctagtgaact gcgcattcat gacctggaag atgacctgga aatgtcatcc
      781 gatgccagtg atgccagtgg agaagagggc agcagagcct ccaaggctaa gaaaaaggcc
      841 ccagtgacca aggcaggcag gaagaagaaa aagaagaagg gctcagatga tgaggccttt
      901 gaggacagtg atgacgggga ctttgagggc caggaggtag actacatgtc tgacggctcc
      961 agcagctcac cggatgaggc agagggcaag cccaaggtgc cccagcagga ggatggcccc
     1021 aagggtgtgg acgaacagag tgagagcagt gaggagagtg aggaggagaa gccccccgag
     1081 gaggacaagg aggaggagga agagaagaag gcccctaccc cacaagagaa gaaacgcagg
     1141 aaagacagca gtgatgactc agacagctca gaagagagcg acattgacag tgagacctcc
     1201 tctgcgctct tcatggcgaa gaagaagaca ccccccaaga gggagcggaa gccatccggg
     1261 ggaagttcaa agggcaccag ccggccagga actcccagtg cagaagcggc aagcacctct
     1321 tctaccctgc gggccgcggc cagcaagctg gaacagggga agcggacaag tgagactcca
     1381 gcagccaagc gccttcggat ggacacaggt ccccagagcc tgtctgggaa gtccacgccc
     1441 agcagcggtg atgtccaggt gacagaggat gctgtgcgcc gctacctgac ccggaagccc
     1501 atgaccacga aggacctgct gaagaagttc cagaccaaga agacggggct gagcagcgag
     1561 cagacagtga atgtgctggc gcagattctc aagcgcctca accctgagcg caagatgatt
     1621 ggggacaaga tgcacttctc cctcaaagag tgatgccaat aaagagagca ggcccaaaaa
     1681 aaaaaaaaaa aaaaaaaaaa aaaaaa
//
