LOCUS       NM_001107318            1527 bp    mRNA    linear   ROD 26-FEB-2024
DEFINITION  Rattus norvegicus general transcription factor IIE subunit 2
            (Gtf2e2), mRNA.
ACCESSION   NM_001107318 XM_001067878 XM_224929
VERSION     NM_001107318.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1527)
  AUTHORS   He Y, Yan C, Fang J, Inouye C, Tjian R, Ivanov I and Nogales E.
  TITLE     Near-atomic resolution visualization of human transcription
            promoter opening
  JOURNAL   Nature 533 (7603), 359-365 (2016)
   PUBMED   27193682
REFERENCE   2  (bases 1 to 1527)
  AUTHORS   Grunberg S and Hahn S.
  TITLE     Structural insights into transcription initiation by RNA polymerase
            II
  JOURNAL   Trends Biochem Sci 38 (12), 603-611 (2013)
   PUBMED   24120742
  REMARK    Review article
REFERENCE   3  (bases 1 to 1527)
  AUTHORS   Castello A, Fischer B, Eichelbaum K, Horos R, Beckmann BM, Strein
            C, Davey NE, Humphreys DT, Preiss T, Steinmetz LM, Krijgsveld J and
            Hentze MW.
  TITLE     Insights into RNA biology from an atlas of mammalian mRNA-binding
            proteins
  JOURNAL   Cell 149 (6), 1393-1406 (2012)
   PUBMED   22658674
REFERENCE   4  (bases 1 to 1527)
  AUTHORS   Shultz MA, Zhang L, Gu YZ, Baker GL, Fannuchi MV, Padua AM, Gurske
            WA, Morin D, Penn SG, Jovanovich SB, Plopper CG and Buckpitt AR.
  TITLE     Gene expression analysis in response to lung toxicants: I.
            Sequencing and microarray development
  JOURNAL   Am J Respir Cell Mol Biol 30 (3), 296-310 (2004)
   PUBMED   12947022
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CF110694.1 and BI293118.1.
            
            On Jan 9, 2008 this sequence version replaced NM_001107318.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: CF110694.1, SRR8487226.9822.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMD00132261,
                                           SAMD00132262 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1198              CF110694.1         17-1214
            1199-1527           BI293118.1         1-329               c
FEATURES             Location/Qualifiers
     source          1..1527
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="Sprague-Dawley"
                     /db_xref="taxon:10116"
                     /chromosome="16"
                     /map="16q12.3"
     gene            1..1527
                     /gene="Gtf2e2"
                     /note="general transcription factor IIE subunit 2"
                     /db_xref="GeneID:306516"
                     /db_xref="RGD:1310134"
     exon            1..38
                     /gene="Gtf2e2"
                     /inference="alignment:Splign:2.1.0"
     exon            39..208
                     /gene="Gtf2e2"
                     /inference="alignment:Splign:2.1.0"
     CDS             43..918
                     /gene="Gtf2e2"
                     /note="general transcription factor IIE, polypeptide 2
                     (beta subunit); general transcription factor IIE,
                     polypeptide 2, beta"
                     /codon_start=1
                     /product="transcription initiation factor IIE subunit
                     beta"
                     /protein_id="NP_001100788.2"
                     /db_xref="GeneID:306516"
                     /db_xref="RGD:1310134"
                     /translation="MDPSLLRDRELFKKRALSTPVVEKRAVPSESPSSSSKKKKAKVE
                     HGGSSGSKQNSDHNNGSFNLKALSGSSGYKFGVLAKIVNYMKTRHQRGDTHPLTLEEI
                     LDETQHLDIGLKQKQWLMTEALVNNPKIEVVDGKYAFKPKYNLKDKKALLRLLDNHDQ
                     RGLGGILLEDIEEGLPNSQKAVKALGDQILFVSRPDKKKILFFNDKSCQFSVDEEFQK
                     LWRSVTVDSMDEEKIEEYLKRQGISSMQESGPKKVASIQRRKKPASQKKRRFKTHNEH
                     LAGVLKDYSDITPGK"
     exon            209..300
                     /gene="Gtf2e2"
                     /inference="alignment:Splign:2.1.0"
     exon            301..408
                     /gene="Gtf2e2"
                     /inference="alignment:Splign:2.1.0"
     exon            409..591
                     /gene="Gtf2e2"
                     /inference="alignment:Splign:2.1.0"
     exon            592..685
                     /gene="Gtf2e2"
                     /inference="alignment:Splign:2.1.0"
     exon            686..801
                     /gene="Gtf2e2"
                     /inference="alignment:Splign:2.1.0"
     exon            802..1513
                     /gene="Gtf2e2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcggaggcca ggaggcggcg cgggttgcgg gtgctgagca ttatggaccc aagcctgttg
       61 agagatcgag aactgttcaa aaaacgagct ctttccactc ctgtggtaga gaaacgtgct
      121 gtgccttcag agtcaccctc ctcctcatcc aagaagaaga aggcaaaagt cgagcatggg
      181 ggatcatcag gctctaaaca aaattcagat cataacaatg gatcatttaa cttgaaagct
      241 ctgtctggaa gctctggata taagttcggt gttcttgcta agattgtgaa ttatatgaaa
      301 acacgacatc agcgaggaga tacgcatccc ttaactctgg aagagatttt ggatgaaaca
      361 cagcatttag acattggact caagcagaaa caatggctaa tgacagaggc tttagtcaac
      421 aatcccaaaa ttgaagtagt agatgggaaa tacgccttca aacctaagta caacttgaaa
      481 gataagaagg ccctgctcag gcttctagat aaccatgacc agcgaggact gggaggcatt
      541 ctcttagaag acatagaaga gggattgcct aattctcaga aagctgtcaa ggctttaggg
      601 gaccagattc tatttgtaag tcgtcctgat aagaagaaaa tactattctt caatgataaa
      661 agctgtcagt tttctgtgga tgaagagttc cagaaactgt ggaggagtgt tactgtggat
      721 tcaatggatg aggagaaaat tgaagagtat ctgaagcgac agggtatttc ttccatgcag
      781 gaatctggac caaagaaagt ggcctctatt cagagaagga aaaagcctgc ttcacagaaa
      841 aagcgacggt ttaagactca caatgaacac ttggctggag tgctgaagga ttactcggac
      901 attacccctg gcaaataggg aatattttta tccataaagt tacagacgca cagtcaagat
      961 ctttcttgat gctctcggga tctgaagact ttctgccttc ccgtctgctc ctcaggactg
     1021 aggagaggag caattcagtt tacagaacag gagcggatta ccaaactcat tattttcatc
     1081 cagcaggcta gtgggactgg gtgttcctgt ttaactttct gggtttgttt gttttatttt
     1141 actagaaaga cacttagcat ggcactcagg tgtctgctgt ttatcttgat ttctaaatgg
     1201 ttctggattc catgttttct cttctgcttt agaacaagtt ggaagatagt gctgaataca
     1261 gcctttgttt attccaagag aaatatttat aataaaatca tttgtaggaa gatctttaag
     1321 aagttaggaa tttcagtttg tctcttcttg aaaatggcag ggagcagctg cagtccctga
     1381 cttgtctgga tgggtgtttg ggatgtgaca gagactggag tcagtactgt tggcacgctt
     1441 gaggacttga tctttggaac acagggtatg cctctggtca ataagctgag caataaaagt
     1501 acactaaata taaaaaaaaa aaaaaaa
//
