LOCUS       NM_001100556            2897 bp    mRNA    linear   ROD 22-MAR-2023
DEFINITION  Rattus norvegicus general transcription factor IIE subunit 1
            (Gtf2e1), mRNA.
ACCESSION   NM_001100556 XM_001062046 XM_221426
VERSION     NM_001100556.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2897)
  AUTHORS   He Y, Yan C, Fang J, Inouye C, Tjian R, Ivanov I and Nogales E.
  TITLE     Near-atomic resolution visualization of human transcription
            promoter opening
  JOURNAL   Nature 533 (7603), 359-365 (2016)
   PUBMED   27193682
REFERENCE   2  (bases 1 to 2897)
  AUTHORS   Grunberg S and Hahn S.
  TITLE     Structural insights into transcription initiation by RNA polymerase
            II
  JOURNAL   Trends Biochem Sci 38 (12), 603-611 (2013)
   PUBMED   24120742
  REMARK    Review article
REFERENCE   3  (bases 1 to 2897)
  AUTHORS   Sabbah M, Kang KI, Tora L and Redeuilh G.
  TITLE     Oestrogen receptor facilitates the formation of preinitiation
            complex assembly: involvement of the general transcription factor
            TFIIB
  JOURNAL   Biochem J 336 (Pt 3) (Pt 3), 639-646 (1998)
   PUBMED   9841876
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            DY311373.1, BC099237.1 and CA509437.1.
            
            On or before Nov 22, 2008 this sequence version replaced
            XM_221426.3, XM_001062046.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC168718.1, SRR8487230.97270.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-626               DY311373.1         36-661
            627-2868            BC099237.1         166-2407
            2869-2897           CA509437.1         1-29                c
FEATURES             Location/Qualifiers
     source          1..2897
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="Sprague-Dawley"
                     /db_xref="taxon:10116"
                     /chromosome="11"
                     /map="11q21"
     gene            1..2897
                     /gene="Gtf2e1"
                     /note="general transcription factor IIE subunit 1"
                     /db_xref="GeneID:303918"
                     /db_xref="RGD:1306851"
     exon            1..96
                     /gene="Gtf2e1"
                     /inference="alignment:Splign:2.1.0"
     exon            97..569
                     /gene="Gtf2e1"
                     /inference="alignment:Splign:2.1.0"
     CDS             122..1438
                     /gene="Gtf2e1"
                     /note="general transcription factor IIE, polypeptide 1
                     (alpha subunit); general transcription factor IIE,
                     polypeptide 1, alpha"
                     /codon_start=1
                     /product="general transcription factor IIE subunit 1"
                     /protein_id="NP_001094026.1"
                     /db_xref="GeneID:303918"
                     /db_xref="RGD:1306851"
                     /translation="MADPDVLTEVPAALKRLAKYVIRGFYGIEHVLALDILIRNPCVK
                     EEDMLELLKFDRKQLRSVLNNLKGDKFIKCRMRVETAADGKTTRHNYYFINYRTLVNV
                     VKYKLDHMRRRIETDERNSTNRASFKCPVCCSTFTDLEANQLFEPMTGTFRCTFCQAE
                     VEEDESAMPKKDARTLLARFNEQIEPIYALLRETEDVNLAYEILEPEPTEIPALKQSK
                     DRAASAAGAAGLAGGHHREAWTNKGPSYEDLYTQNVVISMDDQDDVHRTSLEGKAAKE
                     RPIWLRESTVQGAYGSEEMKEGGIDMDTFQDREEARAGPDDNEEVMRALLIHEKKTSS
                     ATAGSVGAAAPVTAANGSDSESETSESDDDSPPRPAAAAPHHRDEDEEDDEFEEVADD
                     PVVMVAGCPFSYSEVSQRPELVAQMTPEEKEAYIAMGQRMFEDLFE"
     exon            570..771
                     /gene="Gtf2e1"
                     /inference="alignment:Splign:2.1.0"
     exon            772..1013
                     /gene="Gtf2e1"
                     /inference="alignment:Splign:2.1.0"
     exon            1014..2880
                     /gene="Gtf2e1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cgttcgtcct tgtctcgcaa gtggcgtggg ctggctgaag ccggtagttg aggtgctgag
       61 ggcggctgta gtgggagtgt tcgagcatcc atttggtgga agttgaaact taccgttgaa
      121 gatggcagac ccagatgttc tcactgaagt tccagcagca ttgaagcggt tagccaagta
      181 tgtcatccgg ggcttttatg gcattgagca tgtgttggcc ttggacatct tgatccggaa
      241 cccttgtgta aaagaagagg acatgctgga gctgctcaag tttgaccgga agcagcttcg
      301 atccgttttg aataatttaa agggagacaa gttcatcaaa tgcagaatga gggtagagac
      361 tgctgcagat gggaagacca cccgccataa ctactacttc atcaattacc gcactcttgt
      421 taatgtagtg aagtataagc tggaccacat gagaaggagg attgaaacgg atgagagaaa
      481 ctccaccaat cgggcttcct tcaaatgtcc tgtctgctgc agcactttca ctgacctgga
      541 agctaatcag ctgtttgaac ccatgacagg aactttccgc tgcacctttt gccaggcaga
      601 ggtagaagaa gatgaatcag caatgcccaa aaaagatgcg cgcacacttt tggcaaggtt
      661 taatgaacaa attgagccca tttatgcatt gcttcgagag acagaggatg taaacttggc
      721 ctacgaaata cttgaaccag aacccacgga aatcccagcc ctgaagcaga gcaaggaccg
      781 agcagcaagt gctgctggag cggctggcct ggcaggtggg caccaccggg aagcatggac
      841 caacaaaggc ccctcttatg aagacttgta tactcagaat gttgtcatca gcatggacga
      901 ccaagacgat gtgcatcgca cctcgctgga agggaaagcc gccaaagaga gacccatttg
      961 gttgagagag agcactgtcc agggggcgta cggttctgaa gagatgaagg aaggtggcat
     1021 cgacatggac acatttcagg atcgagagga agcccgtgcg gggcctgatg acaacgagga
     1081 ggtcatgcga gctctactca ttcatgagaa gaagacgtct tcggcgacag ctggctcagt
     1141 gggagcagcc gctccggtga ctgctgccaa cggcagtgac tctgagagtg agaccagtga
     1201 gtcggatgac gactctccac cccggccagc agctgcagct cctcatcacc gcgatgaaga
     1261 tgaggaagat gacgagtttg aggaagtagc agatgacccc gttgttatgg tggctggctg
     1321 cccattctcc tacagtgagg ttagccagcg gccagagttg gtagctcaga tgacaccaga
     1381 agaaaaggaa gcctacatag ccatgggcca gcggatgttt gaggatctct tcgagtgaac
     1441 ttccctgctt ttcctgtgtt agcttacttc agagagaaac ttcccggcca gggctgaggg
     1501 gcttttcttt atgtaaagca cccggtagtc tggtacagaa gtgtagtagg agagaaaatc
     1561 tgattttttt ttaatgtaag aaacttccca aaaaggtaga taggttgaaa gtattcagtt
     1621 ccctcatatt actaaagtat taatattttt ctctatttcc ttatctaatt tcttcctttc
     1681 cctcttaaga catatttttc tcactctgac taaaatgttc ctgtctacct tcagaaccct
     1741 gctagggata aacttaccct agtgttgtag ctgcattgtg gccgcttggc acgatttgag
     1801 acgatgcctt atattcctgt caaccaaagc ggcttaccaa gaagcagatc actgcgtagg
     1861 ggagcaccca cacatttcat cttcctcaga attgagtttg gggtgcgcct gtgaaatgag
     1921 tgagagagta caggagagag gggtacctga atcttggatc cacgtctgta gaaccaataa
     1981 agctggtaga ttgtttcgtt ttcatagacc ttttgggctg tacttcaggt gacagagtga
     2041 cagatgacaa agcaggttag ttctaccctc atggaggaat tccagcagca catgtgccaa
     2101 gggtaaggag tctgtgtcca gggttgaaga acagagagca ctgggaacca agccttatgc
     2161 tgcgtctggt cagtgtgatt tacttgggaa tctctgacgt aaagcgagac tggccccact
     2221 ccccagcgct tgctctacag gcctttgcca gggctctgca ttaaggagcc cattccagta
     2281 cagagcagtg ctgattcctc cactccccca actcttcaaa ggccaccaga gcctttatct
     2341 gtctctgagc ctcctctgac atcgtccttc agtgcctcag actacattgt tgagcattgt
     2401 aaccaaggaa cagagtcatc agcacggtgt tcttcttgaa ggcagaactt taaaaataaa
     2461 ggacttccat ataaggtcta caacaattaa agttttacag tatttctcct tgcattgtga
     2521 cttttagtta tcattctgta gtatatgtgt gaagctgggg acgttttagg gaatgtgagc
     2581 ctcatgtaga gagacgacag acatttacct ggttgttgga tgactgaaga ttgacagtct
     2641 gcgtactgca ggttagagct ggttagttta tcgctctaaa gatgttagag gcttctcatg
     2701 gtcgtcatct aatagcatag gtgcaatttg atttaaactt tttttggcac tgaattgtct
     2761 taaaaaacct ttttatgtat ttatcttaaa tacatgaact gttcaacttt aaaattttgt
     2821 tttttaaact ttcatggttg tagaaaaatt taatttttaa aacattaatt ttaaaatgta
     2881 aaaaaaaaaa aaaaaaa
//
