LOCUS       NM_001412186             940 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus general transcription factor 2A subunit 2
            (Gtf2a2), transcript variant 2, mRNA.
ACCESSION   NM_001412186
VERSION     NM_001412186.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 940)
  AUTHORS   He,Y., Yan,C., Fang,J., Inouye,C., Tjian,R., Ivanov,I. and
            Nogales,E.
  TITLE     Near-atomic resolution visualization of human transcription
            promoter opening
  JOURNAL   Nature 533 (7603), 359-365 (2016)
   PUBMED   27193682
REFERENCE   2  (bases 1 to 940)
  AUTHORS   Grunberg,S. and Hahn,S.
  TITLE     Structural insights into transcription initiation by RNA polymerase
            II
  JOURNAL   Trends Biochem Sci 38 (12), 603-611 (2013)
   PUBMED   24120742
  REMARK    Review article
REFERENCE   3  (bases 1 to 940)
  AUTHORS   Anderson,D.M., Beres,B.J., Wilson-Rawls,J. and Rawls,A.
  TITLE     The homeobox gene Mohawk represses transcription by recruiting the
            sin3A/HDAC co-repressor complex
  JOURNAL   Dev Dyn 238 (3), 572-580 (2009)
   PUBMED   19235719
REFERENCE   4  (bases 1 to 940)
  AUTHORS   Yu,S., Jiang,Y., Galson,D.L., Luo,M., Lai,Y., Lu,Y., Ouyang,H.J.,
            Zhang,J. and Xiao,G.
  TITLE     General transcription factor IIA-gamma increases
            osteoblast-specific osteocalcin gene expression via activating
            transcription factor 4 and runt-related transcription factor 2
  JOURNAL   J Biol Chem 283 (9), 5542-5553 (2008)
   PUBMED   18171674
REFERENCE   5  (bases 1 to 940)
  AUTHORS   Han,S.Y., Zhou,L., Upadhyaya,A., Lee,S.H., Parker,K.L. and
            DeJong,J.
  TITLE     TFIIAalpha/beta-like factor is encoded by a germ cell-specific gene
            whose expression is up-regulated with other general transcription
            factors during spermatogenesis in the mouse
  JOURNAL   Biol Reprod 64 (2), 507-517 (2001)
   PUBMED   11159353
REFERENCE   6  (bases 1 to 940)
  AUTHORS   Ozer,J., Bolden,A.H. and Lieberman,P.M.
  TITLE     Transcription factor IIA mutations show activator-specific defects
            and reveal a IIA function distinct from stimulation of TBP-DNA
            binding
  JOURNAL   J Biol Chem 271 (19), 11182-11190 (1996)
   PUBMED   8626665
REFERENCE   7  (bases 1 to 940)
  AUTHORS   DeJong,J., Bernstein,R. and Roeder,R.G.
  TITLE     Human general transcription factor TFIIA: characterization of a
            cDNA encoding the small subunit and requirement for basal and
            activated transcription
  JOURNAL   Proc Natl Acad Sci U S A 92 (8), 3313-3317 (1995)
   PUBMED   7724559
REFERENCE   8  (bases 1 to 940)
  AUTHORS   Sun,X., Ma,D., Sheldon,M., Yeung,K. and Reinberg,D.
  TITLE     Reconstitution of human TFIIA activity from recombinant
            polypeptides: a role in TFIID-mediated transcription
  JOURNAL   Genes Dev 8 (19), 2336-2348 (1994)
   PUBMED   7958900
REFERENCE   9  (bases 1 to 940)
  AUTHORS   Ozer,J., Moore,P.A., Bolden,A.H., Lee,A., Rosen,C.A. and
            Lieberman,P.M.
  TITLE     Molecular cloning of the small (gamma) subunit of human TFIIA
            reveals functions critical for activated transcription
  JOURNAL   Genes Dev 8 (19), 2324-2335 (1994)
   PUBMED   7958899
REFERENCE   10 (bases 1 to 940)
  AUTHORS   Dixon,R.A. and Backman,L.
  TITLE     The concept of compensation in cognitive aging: the case of prose
            processing in adulthood
  JOURNAL   Int J Aging Hum Dev 36 (3), 199-217 (1992)
   PUBMED   1302244
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000008.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643290.29858.1,
                                           SRR26360172.433692.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-94                JAXUCZ010000008.1  79543355-79543448
            95-285              JAXUCZ010000008.1  79546927-79547117
            286-404             JAXUCZ010000008.1  79547290-79547408
            405-509             JAXUCZ010000008.1  79548589-79548693
            510-636             JAXUCZ010000008.1  79553216-79553342
            637-940             JAXUCZ010000008.1  79556181-79556484
FEATURES             Location/Qualifiers
     source          1..940
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="8"
                     /map="8q24"
     gene            1..940
                     /gene="Gtf2a2"
                     /note="general transcription factor 2A subunit 2"
                     /db_xref="GeneID:83828"
                     /db_xref="RGD:620720"
     exon            1..94
                     /gene="Gtf2a2"
                     /inference="alignment:Splign:2.1.0"
     exon            95..285
                     /gene="Gtf2a2"
                     /inference="alignment:Splign:2.1.0"
     exon            286..404
                     /gene="Gtf2a2"
                     /inference="alignment:Splign:2.1.0"
     CDS             333..662
                     /gene="Gtf2a2"
                     /note="TFIIA-gamma; general transcription factor IIA
                     subunit 2; transcription initiation factor IIA gamma
                     chain; general transcription factor IIa, 2 (12kD subunit);
                     general transcription factor2A subunit 2; general
                     transcription factor IIa 2"
                     /codon_start=1
                     /product="transcription initiation factor IIA subunit 2"
                     /protein_id="NP_001399115.1"
                     /db_xref="GeneID:83828"
                     /db_xref="RGD:620720"
                     /translation="MAYQLYRNTTLGNSLQESLDELIQSQQITPQLALQVLLQFDKAI
                     NSALAQRVRNRVNFRGSLNTYRFCDNVWTFVLNDVEFREVTELIKVDKVKIVACDGKN
                     TGSNTTE"
     exon            405..509
                     /gene="Gtf2a2"
                     /inference="alignment:Splign:2.1.0"
     exon            510..636
                     /gene="Gtf2a2"
                     /inference="alignment:Splign:2.1.0"
     exon            637..940
                     /gene="Gtf2a2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 actggcacag ggctgcggtt tccgcggctg aggtggtcgc agcgggctcc ctacctggct
       61 ctgctaccgc cgcggcggaa gcgccttccc tcagtgccat ccttttggtg aaaactctaa
      121 tggaatttta agaaaacaga aaaataaagg tcccaattat agatgtcaag tcactatgtg
      181 actgcaggta gaatgtatgc tatgtggaaa attctacact aagagaaacc tgtgggaaaa
      241 taaagatgta cattttaatg aatatgtcag catactgaat taaaggacat caatgcaagc
      301 ctgaagaaaa agtaatcgct tccttttaag ccatggcata tcagttatac agaaatacaa
      361 ctttggggaa cagtcttcaa gagagccttg atgagctcat acagtctcaa cagatcaccc
      421 cccagcttgc ccttcaagtt ctacttcagt ttgataaagc tataaattca gcattggctc
      481 agagagtcag gaacagagtc aatttcaggg gctctctaaa tacatacaga ttctgcgata
      541 atgtttggac ttttgtattg aatgatgttg aattcagaga ggtgacagaa cttattaaag
      601 tggataaagt gaaaattgta gcctgtgatg gtaaaaatac cggttccaat accacggaat
      661 gagtagagaa attgggcttt tttatgccac cttctattat tttcatcact ttttgaagag
      721 aaacatagaa gagacttttt ttatttattc tcacggtgca gaaataacaa cactgtgcta
      781 tatataccta cccaagggtt ccacagagag aagcatgtga ctctgttctc ttaaatgacc
      841 tttagtacac agcataaaga aatgtaactt ttttttaatg acaaatcaaa agtggttgcc
      901 ttcctaagca tattcttcaa taaaacttgt tttaaaactt
//
