LOCUS       NM_001399042            1630 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus glutathione S-transferase, theta 3 (Gstt3), mRNA.
ACCESSION   NM_001399042 XM_039099012
VERSION     NM_001399042.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1630)
  AUTHORS   Yun,J.W., Kim,C.W., Bae,I.H., Park,Y.H., Chung,J.H., Lim,K.M. and
            Kang,K.S.
  TITLE     Expression levels of pituitary tumor transforming 1 and
            glutathione-S-transferase theta 3 are associated with the
            individual susceptibility to D-galactosamine-induced hepatotoxicity
  JOURNAL   Toxicol Appl Pharmacol 242 (1), 91-99 (2010)
   PUBMED   19800905
  REMARK    GeneRIF: Gstt3 could predict inter-individual susceptibility to
            D-galactosamine induced hepatotoxicity
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000020.1.
            
            On Dec 30, 2021 this sequence version replaced XM_039099012.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: FQ225600.1, SRR26643293.82075.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760389
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-238               JAXUCZ010000020.1  12874618-12874855
            239-326             JAXUCZ010000020.1  12878130-12878217
            327-477             JAXUCZ010000020.1  12879175-12879325
            478-654             JAXUCZ010000020.1  12880039-12880215
            655-1630            JAXUCZ010000020.1  12880999-12881974
FEATURES             Location/Qualifiers
     source          1..1630
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="20"
                     /map="20p12"
     gene            1..1630
                     /gene="Gstt3"
                     /gene_synonym="RGD1562732"
                     /note="glutathione S-transferase, theta 3"
                     /db_xref="GeneID:499422"
                     /db_xref="RGD:1562732"
     exon            1..238
                     /gene="Gstt3"
                     /gene_synonym="RGD1562732"
                     /inference="alignment:Splign:2.1.0"
     CDS             127..852
                     /gene="Gstt3"
                     /gene_synonym="RGD1562732"
                     /codon_start=1
                     /product="glutathione S-transferase, theta 3"
                     /protein_id="NP_001385971.1"
                     /db_xref="GeneID:499422"
                     /db_xref="RGD:1562732"
                     /translation="MGLELYLDLMSQPCRAVYIFAKKNGIPFQLRTIELLKGQHYTDA
                     FAQVNPLRKVPALKDGDFVLAESVAILLYLSRKYKAPDHWYPQDLQTRARVDEYLAWQ
                     HTALRSCCSRAMWQKMMFPVFLGQPVPPERLASTLAELDGCLQMLEDKFLQNKAFLTG
                     PHISVADLVAITELMHPVSAGCKIFESRPKLAAWRQRVEAAVGESLFQEAHEVVLKAK
                     DMPPLMDPTLKEKLKLSVQCLLH"
     exon            239..326
                     /gene="Gstt3"
                     /gene_synonym="RGD1562732"
                     /inference="alignment:Splign:2.1.0"
     exon            327..477
                     /gene="Gstt3"
                     /gene_synonym="RGD1562732"
                     /inference="alignment:Splign:2.1.0"
     exon            478..654
                     /gene="Gstt3"
                     /gene_synonym="RGD1562732"
                     /inference="alignment:Splign:2.1.0"
     exon            655..1630
                     /gene="Gstt3"
                     /gene_synonym="RGD1562732"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 actgaaggac taagacccag ccgttcctgc tcgccgttgc agctgcttct gcctctgtcc
       61 accgaggcag ttcacccgag gccgatctcc gaggtctgcc agcggctact tcccacagcc
      121 tccgccatgg gtctggagct ctacctggac ctgatgtccc agccctgccg tgccgtctac
      181 atcttcgcca agaagaacgg catccccttc cagctgcgta ccatcgagct gcttaaaggt
      241 cagcattaca ctgatgcctt tgcccaggtg aaccctttga ggaaggtgcc ggctttgaag
      301 gatggggact tcgtcttggc agagagtgtg gccatcttgc tgtatttgag tagaaagtac
      361 aaggcacctg accactggta ccctcaggac ctacagaccc gagctcgtgt ggatgagtac
      421 ctggcttggc agcacacagc cctgcggagc tgttgcagca gggccatgtg gcagaagatg
      481 atgttccctg tgttcctggg acagccggtt cctcctgaga ggttggcatc caccttggcc
      541 gaactggatg gatgcctgca gatgctggag gacaagttcc tgcagaacaa ggccttccta
      601 acaggacccc atatctccgt ggctgacttg gtggccatca cagaactgat gcatcctgtc
      661 agtgctggct gcaaaatctt cgagagccga cccaaactgg ctgcgtggcg tcagcgggtg
      721 gaagccgcag tgggggagag cctcttccag gaggcccatg aagtcgtcct gaaggccaaa
      781 gatatgcctc ccttgatgga cccgaccttg aaggagaaac tgaagctctc tgttcaatgc
      841 ctgctgcact gagggaacag cctgaagtca agggaaactt ggtgtgtgcg tgtgtgtgtg
      901 tgtgtacacg caagtgaaga ggtgaggctg tgtctttggc agtcactagg acacagagtc
      961 tctggtccag tttcctctcg gcatccccgg tgcttcctct gtgtccccac tcggtttgtg
     1021 ctgtgacgtc agctcttatc tgacttctgg agagagctgc aggaaaatac ttgggagaaa
     1081 cttacctggc catattcctt ttctttgaaa ctttacaaag caacctttcc ccaacctcca
     1141 agtcatacct ttctggttcc ctggttcctt ttctgacctc acactgaccc ccgtgccctt
     1201 cgtatatgta tgtgcacaca catacataca cacccacacc cacacacaca cacacacaca
     1261 caatttgata tctggcacca cgtggacctc tgtgctcctc aaccccagcg cctcccttcc
     1321 ttagttttga cagggagact ctatgatttt tgagttgaat acatatcaga gatggggatt
     1381 gactgactag tgaaaggcct ttgtcctcag ggtcttcgct ccctggtata ggtggggtgc
     1441 agggctggtt cgtgactgcc cttgcaggag tggaagtttc ctgatgttct gactttccaa
     1501 attcttgctc taagccttct aactctgact gttgccttct gcctgtctcc agctccaaac
     1561 tgtcacagga tgtctggtgc cattggacat ctcttatgcg ccttacctaa taaagacatc
     1621 attaacagca
//
