LOCUS       NM_001106464            1169 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus glutathione S-transferase, mu 5-like (Gstm5l),
            mRNA.
ACCESSION   NM_001106464 XM_215682
VERSION     NM_001106464.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1169)
  AUTHORS   Norrgard,M.A., Ivarsson,Y., Tars,K. and Mannervik,B.
  TITLE     Alternative mutations of a positively selected residue elicit gain
            or loss of functionalities in enzyme evolution
  JOURNAL   Proc Natl Acad Sci U S A 103 (13), 4876-4881 (2006)
   PUBMED   16549767
REFERENCE   2  (bases 1 to 1169)
  AUTHORS   Townsend,D.M. and Tew,K.D.
  TITLE     The role of glutathione-S-transferase in anti-cancer drug
            resistance
  JOURNAL   Oncogene 22 (47), 7369-7375 (2003)
   PUBMED   14576844
  REMARK    Review article
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473952.1.
            
            On Oct 4, 2007 this sequence version replaced XM_215682.4.
            
            ##Evidence-Data-START##
            CDS exon combination :: DN933830.1, DN933404.1 [ECO:0000331]
            RNAseq introns       :: mixed sample support SAMD00155331,
                                    SAMEA5760383 [ECO:0006172]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..1169
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="2"
                     /map="2q34"
     gene            1..1169
                     /gene="Gstm5l"
                     /gene_synonym="Gstm6l"
                     /note="glutathione S-transferase, mu 5-like"
                     /db_xref="GeneID:295362"
                     /db_xref="RGD:1311731"
     exon            1..82
                     /gene="Gstm5l"
                     /gene_synonym="Gstm6l"
                     /inference="alignment:Splign:2.1.0"
     CDS             73..627
                     /gene="Gstm5l"
                     /gene_synonym="Gstm6l"
                     /note="glutathione S-transferase M6-like; glutathione
                     S-transferase, mu 6-like"
                     /codon_start=1
                     /product="glutathione S-transferase, mu 5-like"
                     /protein_id="NP_001099934.1"
                     /db_xref="GeneID:295362"
                     /db_xref="RGD:1311731"
                     /translation="MGDAPDYDRSQWLSEKFKLGLDIPNLPYLIDGSHKITQSNAILR
                     YLGRKHNLCGETEEERLRVDILENQAVDTRRQLSMVCYSPEFEKRKPEYLEGLPDKMK
                     LYSEFLGKQLWFAGNKITYVDFLVYDVLDKHRMFELKCLDAFPNLKDFMARFETLEKI
                     SAYMKSSRFLSGPVYLKTALWGNK"
     exon            83..147
                     /gene="Gstm5l"
                     /gene_synonym="Gstm6l"
                     /inference="alignment:Splign:2.1.0"
     exon            148..229
                     /gene="Gstm5l"
                     /gene_synonym="Gstm6l"
                     /inference="alignment:Splign:2.1.0"
     exon            230..330
                     /gene="Gstm5l"
                     /gene_synonym="Gstm6l"
                     /inference="alignment:Splign:2.1.0"
     exon            331..426
                     /gene="Gstm5l"
                     /gene_synonym="Gstm6l"
                     /inference="alignment:Splign:2.1.0"
     exon            427..537
                     /gene="Gstm5l"
                     /gene_synonym="Gstm6l"
                     /inference="alignment:Splign:2.1.0"
     exon            538..1169
                     /gene="Gstm5l"
                     /gene_synonym="Gstm6l"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tcctagttgg gtcaagccat ccgtctgctc ctggaataca caggttcaag ctatgaggag
       61 aagagataca ccatggggga cgctcccgac tatgacagaa gccagtggct gagtgagaag
      121 ttcaaactgg gcctggacat tcctaatctg ccctacttaa tcgatgggtc acacaagatc
      181 acccagagca atgccatcct gcgctacctt ggccggaagc acaacctgtg tggagagaca
      241 gaagaagaga gactccgtgt ggacattttg gagaaccagg ccgtggacac tcgtaggcag
      301 ctttcaatgg tctgctacag ccctgagttt gagaaacgga agccagagta cttagagggt
      361 ctccctgaca agatgaagct ctactctgag ttcctgggca agcagctatg gtttgcaggg
      421 aacaagatta cctatgtgga tttccttgtt tatgatgtcc tcgataagca ccgtatgttt
      481 gagctcaagt gcctggacgc ctttccaaat ctgaaggact tcatggctcg atttgagacc
      541 cttgagaaga tctctgccta catgaagtcc agccgcttcc tttcaggccc tgtgtatttg
      601 aagacagcgc tgtggggtaa caagtagagc gcccgtaata ccagggccag gaggagattt
      661 acctctatgc ttgcggtcca tggtctgggg cccatctgcg tccccgggca tctctgtatc
      721 agtcttccca cctccgttct tctctgaaag gtgttagtga ctccgctttc tacccagcct
      781 ttctgtaagg ggaggttctc aaactcaggt ctagttccct aattggttct tgatgtgtca
      841 ataaagaagg ctgggagcca attgctgggc ggaaggtata ggtgggactt ccgggtccca
      901 agagaaaaag gagattcagg gaaagataga ggggcttttt ctgctgtgct tcggagtaag
      961 aaggtaacag tcatgtaagg tcttccggca gctagggcct gtggcctccg caacaggcgg
     1021 atagccaagg atgttggcag gggctggctg atacaagtca ctaagtttag ggcagaggga
     1081 gatggagata ataaactggt aagagcacgc ctttccaggc cgttgttatc tgagcccagc
     1141 aattgtgcct agcaggcaaa ttctaaagt
//
