LOCUS       NM_001024304            1583 bp    mRNA    linear   ROD 30-JUL-2024
DEFINITION  Rattus norvegicus glutathione S-transferase mu 4 (Gstm4), mRNA.
ACCESSION   NM_001024304 NM_001139485 XM_575013
VERSION     NM_001024304.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1583)
  AUTHORS   Dalli,J., Vlasakov,I., Riley,I.R., Rodriguez,A.R., Spur,B.W.,
            Petasis,N.A., Chiang,N. and Serhan,C.N.
  TITLE     Maresin conjugates in tissue regeneration biosynthesis enzymes in
            human macrophages
  JOURNAL   Proc Natl Acad Sci U S A 113 (43), 12232-12237 (2016)
   PUBMED   27791009
REFERENCE   2  (bases 1 to 1583)
  AUTHORS   Guo,J., Zimniak,L., Zimniak,P., Orchard,J.L. and Singh,S.V.
  TITLE     Cloning and expression of a novel Mu class murine glutathione
            transferase isoenzyme
  JOURNAL   Biochem J 366 (Pt 3), 817-824 (2002)
   PUBMED   12069689
REFERENCE   3  (bases 1 to 1583)
  AUTHORS   Comstock,K.E., Widersten,M., Hao,X.Y., Henner,W.D. and Mannervik,B.
  TITLE     A comparison of the enzymatic and physicochemical properties of
            human glutathione transferase M4-4 and three other human Mu class
            enzymes
  JOURNAL   Arch Biochem Biophys 311 (2), 487-495 (1994)
   PUBMED   8203914
REFERENCE   4  (bases 1 to 1583)
  AUTHORS   Ross,V.L. and Board,P.G.
  TITLE     Molecular cloning and heterologous expression of an alternatively
            spliced human Mu class glutathione S-transferase transcript
  JOURNAL   Biochem J 294 (Pt 2) (Pt 2), 373-380 (1993)
   PUBMED   8373352
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC091199.1.
            
            On or before Nov 24, 2010 this sequence version replaced
            NM_001139485.1, XM_575013.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC091199.1, FQ218403.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMD00132261,
                                           SAMD00132262 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1583
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="2"
                     /map="2q34"
     gene            1..1583
                     /gene="Gstm4"
                     /gene_synonym="GSTM4-4"
                     /note="glutathione S-transferase mu 4"
                     /db_xref="GeneID:499689"
                     /db_xref="RGD:1565825"
     exon            1..126
                     /gene="Gstm4"
                     /gene_synonym="GSTM4-4"
                     /inference="alignment:Splign:2.1.0"
     CDS             91..747
                     /gene="Gstm4"
                     /gene_synonym="GSTM4-4"
                     /EC_number="2.5.1.18"
                     /EC_number="4.4.1.20"
                     /note="glutathione S-transferase mu 3; glutathione
                     S-transferase M4; GST class-mu 4; leukotriene C4 synthase
                     GSTM4"
                     /codon_start=1
                     /product="glutathione S-transferase Mu 4"
                     /protein_id="NP_001019475.1"
                     /db_xref="GeneID:499689"
                     /db_xref="RGD:1565825"
                     /translation="MPMTLGYWDIRGLAHAIRLLLEYTDSSYEEKRYTMGDAPDYDRS
                     QWLSEKFKLGLDFPNLPYLIDGSHKITQSNAILRYIARKHNLCGETEEEKIRVDILEN
                     QAMDVSNQLARVCYSPDFENLKAEYLEQLPGMMELFSQFLGKQTWFVGEKITFVDFLA
                     YDILDLHLIFEPKCLDAFPNLKDFVARFEGLKKISVYMKTSRFLRTPLYTRVATWGNK
                     "
     exon            127..202
                     /gene="Gstm4"
                     /gene_synonym="GSTM4-4"
                     /inference="alignment:Splign:2.1.0"
     exon            203..267
                     /gene="Gstm4"
                     /gene_synonym="GSTM4-4"
                     /inference="alignment:Splign:2.1.0"
     exon            268..349
                     /gene="Gstm4"
                     /gene_synonym="GSTM4-4"
                     /inference="alignment:Splign:2.1.0"
     exon            350..450
                     /gene="Gstm4"
                     /gene_synonym="GSTM4-4"
                     /inference="alignment:Splign:2.1.0"
     exon            451..546
                     /gene="Gstm4"
                     /gene_synonym="GSTM4-4"
                     /inference="alignment:Splign:2.1.0"
     exon            547..657
                     /gene="Gstm4"
                     /gene_synonym="GSTM4-4"
                     /inference="alignment:Splign:2.1.0"
     exon            658..1558
                     /gene="Gstm4"
                     /gene_synonym="GSTM4-4"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ccagccccgc ccagctaccc gagggctcta ggataaagtc aaagctactc acaccggagg
       61 ctagtggact cagtctcagg caccagcatc atgcctatga cactgggtta ctgggacatc
      121 cgtgggctgg ctcatgctat tcgattactc ctggaataca cagactcaag ctatgaggag
      181 aagagataca ccatgggcga cgctcctgac tatgacagaa gccagtggct gagtgagaag
      241 ttcaaactgg gcctggactt ccccaatctg ccctacttaa tcgatgggtc acacaagatc
      301 acccagagca atgccatcct gcgctatatt gcccgaaagc acaacctgtg tggggagaca
      361 gaagaagaga agattcgtgt ggacattttg gagaaccagg ctatggatgt ctccaatcag
      421 ctggctagag tctgttacag cccagacttt gagaacctga aggcggaata tttggagcag
      481 ctccctggga tgatggagct cttctcacag ttcctgggga agcagacgtg gttcgttggt
      541 gaaaagatta cttttgtaga tttccttgct tatgatatcc tggacctgca ccttatattc
      601 gaacccaagt gcctggatgc cttcccaaac ctgaaggact ttgtggcccg cttcgaggga
      661 ctgaagaaga tctctgttta catgaagacc agccgcttcc tccggacacc cctatataca
      721 agggtggcta cttggggcaa taagtagggc tttgactcgg gcaggaagtg ggaacctggg
      781 gttctgggaa cagttgagat tcccgtatcc ctggcgctac cttctaccta tccccttcct
      841 gactgcagaa tgtcaagggt ctcctttcac ccagtccttg ccccttcaag ccctctacag
      901 cctaggcccc tggttttctt tagcaaagtg cccttctagc atgactgtgt cctgtgccca
      961 cttgatggct ttcctgtcag ttgctgtgct gctgtgaaga gttgagactt catcagcgct
     1021 cagcctggga ctccccatgc ttgtctggag actggagatg cctgatgtat ggaggtccct
     1081 gcacagctct tttggatctc tcctgtaaag ctcgaatcac actggctctg gcttctgcac
     1141 tgccagcttt tactgcgatc tccagtgcct gcctagtgac cctggcagac actgtgttca
     1201 cagggatttc agttggatag gcaggggttt gggacttcct ggcctcacct gagtttcaca
     1261 ggaggcagct gcagaaggct ctgtggagct caaagggagc ttggatctct tttatgctag
     1321 cagcactgag gtttgtcacc caggtctcag ggttggggat ccaggctggt gggagtcccc
     1381 aacagtaagc caggatcctc tctgccagct gtgctagggc tgccttatat ctgtgtctcc
     1441 aggatcctgt ctctgatgcc ttcagggtat cctgtcttgg ttacaaggga tggggaacat
     1501 cttggttaat cccttctctc tgtgagttcc cgtgaaataa atttcttcat gttcataaaa
     1561 aaaaaaaaaa aaaaaaaaaa aaa
//
