LOCUS       NM_001003978            2568 bp    mRNA    linear   ROD 26-FEB-2024
DEFINITION  Rattus norvegicus G1 to S phase transition 1 (Gspt1), mRNA.
ACCESSION   NM_001003978 XM_220151
VERSION     NM_001003978.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2568)
  AUTHORS   Wang X, Xuan Y, Han Y, Ding X, Ye K, Yang F, Gao P, Goff SP and Gao
            G.
  TITLE     Regulation of HIV-1 Gag-Pol Expression by Shiftless, an Inhibitor
            of Programmed -1 Ribosomal Frameshifting
  JOURNAL   Cell 176 (3), 625-635 (2019)
   PUBMED   30682371
REFERENCE   2  (bases 1 to 2568)
  AUTHORS   Castello A, Fischer B, Eichelbaum K, Horos R, Beckmann BM, Strein
            C, Davey NE, Humphreys DT, Preiss T, Steinmetz LM, Krijgsveld J and
            Hentze MW.
  TITLE     Insights into RNA biology from an atlas of mammalian mRNA-binding
            proteins
  JOURNAL   Cell 149 (6), 1393-1406 (2012)
   PUBMED   22658674
REFERENCE   3  (bases 1 to 2568)
  AUTHORS   Figaro S, Scrima N, Buckingham RH and Heurgue-Hamard V.
  TITLE     HemK2 protein, encoded on human chromosome 21, methylates
            translation termination factor eRF1
  JOURNAL   FEBS Lett 582 (16), 2352-2356 (2008)
   PUBMED   18539146
REFERENCE   4  (bases 1 to 2568)
  AUTHORS   Janzen DM and Geballe AP.
  TITLE     The effect of eukaryotic release factor depletion on translation
            termination in human cell lines
  JOURNAL   Nucleic Acids Res 32 (15), 4491-4502 (2004)
   PUBMED   15326224
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 2568)
  AUTHORS   Hegde R, Srinivasula SM, Datta P, Madesh M, Wassell R, Zhang Z,
            Cheong N, Nejmeh J, Fernandes-Alnemri T, Hoshino S and Alnemri ES.
  TITLE     The polypeptide chain-releasing factor GSPT1/eRF3 is
            proteolytically processed into an IAP-binding protein
  JOURNAL   J Biol Chem 278 (40), 38699-38706 (2003)
   PUBMED   12865429
REFERENCE   6  (bases 1 to 2568)
  AUTHORS   Hoshino S, Imai M, Mizutani M, Kikuchi Y, Hanaoka F, Ui M and
            Katada T.
  TITLE     Molecular cloning of a novel member of the eukaryotic polypeptide
            chain-releasing factors (eRF). Its identification as eRF3
            interacting with eRF1
  JOURNAL   J Biol Chem 273 (35), 22254-22259 (1998)
   PUBMED   9712840
REFERENCE   7  (bases 1 to 2568)
  AUTHORS   Dreux C, Laplanche JL and Chatelain J.
  TITLE     [Human transmissible dementia: prion diseases?]
  JOURNAL   Bull Acad Natl Med 176 (8), 1279-1291 (1992)
   PUBMED   1300226
  REMARK    Review article
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC079092.1.
            
            [WARNING] On May 2, 2024 this sequence was replaced by
            NM_001003978.2.
            
            On Aug 30, 2004 this sequence version replaced XM_220151.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC079092.1, SRR8487227.217594.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2568
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="10"
                     /map="10q11"
     gene            1..2568
                     /gene="Gspt1"
                     /note="G1 to S phase transition 1"
                     /db_xref="GeneID:24420"
                     /db_xref="RGD:2751"
     exon            1..543
                     /gene="Gspt1"
                     /inference="alignment:Splign:2.1.0"
     CDS             195..2105
                     /gene="Gspt1"
                     /note="G1 to S phase transition protein 1; eukaryotic
                     peptide chain release factor GTP-binding subunit
                     ERF3B-like; G1 to phase transition 1"
                     /codon_start=1
                     /product="eukaryotic peptide chain release factor
                     GTP-binding subunit ERF3A"
                     /protein_id="NP_001003978.1"
                     /db_xref="GeneID:24420"
                     /db_xref="RGD:2751"
                     /translation="MDPSSGGGGGGGGGGGGSSSSSSDSAPDCWDQTDMEAPGPGPCG
                     GGSMAAVAEAQRENLSAAFSRQLNVNAKPFVPNVHAAEFVPSFLRGPAQPPLSPAGAA
                     GGDHGAGSSAGGPSEPVESSQEQSLCEGSNSTVSMELSEPVVENGETEMSPEESWEHK
                     EEISEAEPAGGGSSGDGRPPEESTQEMMEEEEEIPKPKSVVAPPGAPKKEHVNVVFIG
                     HVDAGKSTIGGQIMYLTGMVDKRTLEKYEREAKEKNRETWYLSWALDTNQEERDKGKT
                     VEVGRAYFETEKKHFTILDAPGHKSFVPNMIGGASQADLAVLVISARKGEFETGFEKG
                     GQTREHAMLAKTAGVKHLIVLINKMDDPTVNWSNERYEECKEKLIPFLKKVGFNPKKD
                     IHFMPCSGLTGANLKEQSDFCPWYIGLPFIPYLDNLPNFNRSVDGPIRLPIVDKYKDM
                     GTVVLGKLESGSICKGQQLVMMPNKHNVEVLGILSDDVETDSVAPGENLKIRLKGIEE
                     EEILPGFILCDLNNLCHSGRTFDAQIVIIEHKSIICPGYNAVLHIHTCIEEVEITALI
                     CLVDKKSGEKSKTRPRFVKQDQVCIARLRTAGTICLETFKDFPQMGRFTLRDEGKTIA
                     IGKVLKLVPEKD"
     exon            544..582
                     /gene="Gspt1"
                     /inference="alignment:Splign:2.1.0"
     exon            583..624
                     /gene="Gspt1"
                     /inference="alignment:Splign:2.1.0"
     exon            625..855
                     /gene="Gspt1"
                     /inference="alignment:Splign:2.1.0"
     exon            856..889
                     /gene="Gspt1"
                     /inference="alignment:Splign:2.1.0"
     exon            890..967
                     /gene="Gspt1"
                     /inference="alignment:Splign:2.1.0"
     exon            968..1148
                     /gene="Gspt1"
                     /inference="alignment:Splign:2.1.0"
     exon            1149..1303
                     /gene="Gspt1"
                     /inference="alignment:Splign:2.1.0"
     exon            1304..1444
                     /gene="Gspt1"
                     /inference="alignment:Splign:2.1.0"
     exon            1445..1538
                     /gene="Gspt1"
                     /inference="alignment:Splign:2.1.0"
     exon            1539..1619
                     /gene="Gspt1"
                     /inference="alignment:Splign:2.1.0"
     exon            1620..1793
                     /gene="Gspt1"
                     /inference="alignment:Splign:2.1.0"
     exon            1794..1883
                     /gene="Gspt1"
                     /inference="alignment:Splign:2.1.0"
     exon            1884..2052
                     /gene="Gspt1"
                     /inference="alignment:Splign:2.1.0"
     exon            2053..2545
                     /gene="Gspt1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gccgctgtcg ccccggtcgc gagtgctcag tctggactgt agctgctgcc caggacgccg
       61 gcgagtgagt cgttggtctc cagctcccca gtcttgccac cttccctggg tcattgcggc
      121 ctgctcctcc ccggtcggcc gcccccgcct ccatttcccg ccctctcttc accacacaca
      181 cggccccccc gatcatggat cccagcagcg gaggtggtgg cggaggcggc ggcggcggcg
      241 gcgggagcag cagcagcagt agcgactctg cgcccgactg ctgggaccag accgatatgg
      301 aggctcccgg gccggggcct tgcggcggtg gctccatggc cgcggtggcc gaggcccagc
      361 gtgagaacct cagcgcggct ttcagccggc aactcaacgt caacgccaag cccttcgtcc
      421 ccaacgtcca cgccgcggaa ttcgtgccgt ctttcctgcg aggtccggcc cagccgccgc
      481 tatccccggc tggcgcggcc ggcggtgacc acggagcggg cagcagcgcg ggaggccctt
      541 cggaacctgt ggagtcctct caagagcagt cattgtgtga aggttcaaat tctactgtta
      601 gcatggaact ttcagaacct gttgtagaaa atggagagac agaaatgtcc ccagaagaat
      661 catgggagca caaagaagaa ataagtgaag ccgagccagc aggtggtggt tcctcaggag
      721 atggaaggcc accagaggaa agcacccaag aaatgatgga ggaggaagaa gaaataccaa
      781 aacctaagtc agtggtggca ccaccaggcg ctcctaagaa agagcatgta aatgtagtgt
      841 tcatcgggca tgtggatgct ggcaagtcaa ccattggagg acaaataatg tatttgactg
      901 gaatggtcga caaaagaaca cttgagaaat atgaacgaga agctaaagaa aaaaacagag
      961 aaacttggta cttgtcttgg gccttagaca caaatcagga agagcgagac aagggtaaaa
     1021 cagtagaggt gggccgtgcc tattttgaaa cggaaaaaaa gcattttaca atcctagatg
     1081 ctcctggcca taagagtttt gtcccaaata tgattggtgg tgcctctcaa gctgacttgg
     1141 ctgtactggt aatctcagcc cggaaaggag agtttgaaac tggatttgaa aaaggaggac
     1201 agacaagaga acatgcgatg ttggcaaaga cagcaggtgt caaacactta atcgtgctta
     1261 ttaataagat ggatgatcca acagtaaact ggagcaatga gagatatgaa gaatgcaaag
     1321 agaaattaat accattttta aagaaagttg gcttcaatcc caaaaaggac attcatttta
     1381 tgccctgctc aggactgaca ggagcaaatc ttaaagagca atcagatttc tgtccttggt
     1441 acattggctt accatttatt ccatatctgg ataatttgcc aaacttcaat agatcagttg
     1501 atggaccaat caggctgcca attgtggata agtacaagga tatggggact gtggtcctgg
     1561 gaaagctgga atctggatcc atctgtaaag gccagcagct cgtaatgatg cccaataagc
     1621 acaacgtgga ggtccttgga atactttctg atgatgtaga gacggactct gtagctccag
     1681 gtgaaaacct caaaatcaga ctgaaaggga ttgaagagga agagattctt ccaggattca
     1741 tcctctgtga tcttaataat ctttgtcatt ctggacgcac attcgatgcc cagatagtga
     1801 ttatagagca caagtccatc atctgcccag ggtataatgc ggtgctgcac attcacacct
     1861 gtatcgagga agtcgagata acggccttaa tctgcttggt agacaaaaaa tcaggagaaa
     1921 aaagtaagac tcgaccccgt tttgtaaagc aagatcaagt atgcattgct cgtttaagga
     1981 cagcaggaac catctgcctg gagaccttta aggacttccc tcagatggga cgttttacct
     2041 taagagatga aggtaagacc attgcaattg gaaaagttct gaaactggtt ccagagaaag
     2101 actaagcatt tccttgatga ccctgcacaa tactgtgagg aaaattgact gcaaaagcct
     2161 acttcacacc gccttctctt actttctgcc cattgacaaa cctctcccca tattttgcaa
     2221 agaaaattcc cagcaaaagt ccacatcatg tcagctttct catattgaga gcttggctat
     2281 gccagtttga cttccccaag agtttgcccc acaaactttg cttccttgga cacatttggc
     2341 aatagctttg taagtgatgt ggacatgatt gcctacaata aggaaaccta caggaagttt
     2401 tttatttttc attttcccct taggcatagt tagtcttttt ctccccaggc agatcattct
     2461 gagtgtgcaa gtgtgtgtgc acatgttaaa aagacaacta ccatgttaat aaaatattca
     2521 atttgaaacc ctttcggtat ttgaaaaaaa aaaaaaaaaa aaaaaaaa
//
