LOCUS       NM_001014198            1629 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus GSK3B interacting protein (Gskip), mRNA.
ACCESSION   NM_001014198 XM_343105
VERSION     NM_001014198.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1629)
  AUTHORS   Dema,A., Schroter,M.F., Perets,E., Skroblin,P., Moutty,M.C.,
            Deak,V.A., Birchmeier,W. and Klussmann,E.
  TITLE     The A-Kinase Anchoring Protein (AKAP) Glycogen Synthase Kinase
            3beta Interaction Protein (GSKIP) Regulates beta-Catenin through
            Its Interactions with Both Protein Kinase A (PKA) and GSK3beta
  JOURNAL   J Biol Chem 291 (37), 19618-19630 (2016)
   PUBMED   27484798
REFERENCE   2  (bases 1 to 1629)
  AUTHORS   Loh,J.K., Lin,C.C., Yang,M.C., Chou,C.H., Chen,W.S., Hong,M.C.,
            Cho,C.L., Hsu,C.M., Cheng,J.T., Chou,A.K., Chang,C.H., Tseng,C.N.,
            Wang,C.H., Lieu,A.S., Howng,S.L. and Hong,Y.R.
  TITLE     GSKIP- and GSK3-mediated anchoring strengthens cAMP/PKA/Drp1 axis
            signaling in the regulation of mitochondrial elongation
  JOURNAL   Biochim Biophys Acta 1853 (8), 1796-1807 (2015)
   PUBMED   25920809
REFERENCE   3  (bases 1 to 1629)
  AUTHORS   Hundsrucker,C., Skroblin,P., Christian,F., Zenn,H.M., Popara,V.,
            Joshi,M., Eichhorst,J., Wiesner,B., Herberg,F.W., Reif,B.,
            Rosenthal,W. and Klussmann,E.
  TITLE     Glycogen synthase kinase 3beta interaction protein functions as an
            A-kinase anchoring protein
  JOURNAL   J Biol Chem 285 (8), 5507-5521 (2010)
   PUBMED   20007971
REFERENCE   4  (bases 1 to 1629)
  AUTHORS   Lin,C.C., Chou,C.H., Howng,S.L., Hsu,C.Y., Hwang,C.C., Wang,C.,
            Hsu,C.M. and Hong,Y.R.
  TITLE     GSKIP, an inhibitor of GSK3beta, mediates the
            N-cadherin/beta-catenin pool in the differentiation of SH-SY5Y
            cells
  JOURNAL   J Cell Biochem 108 (6), 1325-1336 (2009)
   PUBMED   19830702
REFERENCE   5  (bases 1 to 1629)
  AUTHORS   Chou,H.Y., Howng,S.L., Cheng,T.S., Hsiao,Y.L., Lieu,A.S., Loh,J.K.,
            Hwang,S.L., Lin,C.C., Hsu,C.M., Wang,C., Lee,C.I., Lu,P.J.,
            Chou,C.K., Huang,C.Y. and Hong,Y.R.
  TITLE     GSKIP is homologous to the Axin GSK3beta interaction domain and
            functions as a negative regulator of GSK3beta
  JOURNAL   Biochemistry 45 (38), 11379-11389 (2006)
   PUBMED   16981698
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            FM111441.1, BC087681.1 and AA819750.1.
            
            On Oct 1, 2011 this sequence version replaced NM_001014198.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: CB568931.1, BC087681.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-23                FM111441.1         4-26
            24-1611             BC087681.1         1-1588
            1612-1629           AA819750.1         1-18                c
FEATURES             Location/Qualifiers
     source          1..1629
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="6"
                     /map="6q32"
     gene            1..1629
                     /gene="Gskip"
                     /gene_synonym="RGD1308470"
                     /note="GSK3B interacting protein"
                     /db_xref="GeneID:362778"
                     /db_xref="RGD:1308470"
     exon            1..82
                     /gene="Gskip"
                     /gene_synonym="RGD1308470"
                     /inference="alignment:Splign:2.1.0"
     CDS             69..503
                     /gene="Gskip"
                     /gene_synonym="RGD1308470"
                     /note="GSK3-beta interaction protein"
                     /codon_start=1
                     /product="GSK3B-interacting protein"
                     /protein_id="NP_001014220.2"
                     /db_xref="GeneID:362778"
                     /db_xref="RGD:1308470"
                     /translation="MGARRMETDCNPVDLSSMSGFEEGSELNGFEGTDMKDMQLEAEA
                     VVNDVLFAVNNMFVSKSLPCADDVAYINVETKERNRYCLELTEAGLRVVGYAFDQVED
                     HLQTPYHETVYSLLDTLSPAYREAFGNALLQRLEALKRDGQS"
     exon            83..341
                     /gene="Gskip"
                     /gene_synonym="RGD1308470"
                     /inference="alignment:Splign:2.1.0"
     exon            342..1615
                     /gene="Gskip"
                     /gene_synonym="RGD1308470"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gggggcgggg gtggtgccgg caccgcaagt ctggctccag acgcctcggg acgaggaaga
       61 agaggaacat gggagctcgc agaatggaaa cagactgtaa tcccgtggat ctaagcagta
      121 tgtctggatt cgaagaaggc tccgagctca acgggtttga aggaacagat atgaaggaca
      181 tgcagctgga ggctgaggcc gttgtcaatg acgttctctt tgctgtcaac aacatgtttg
      241 tctcaaaaag cctgccctgt gcagacgatg tggcttacat caatgtggag acaaaggaaa
      301 gaaacagata ctgcctggag ctcacagaag cagggctcag ggtggtgggc tatgcttttg
      361 accaggtgga ggaccatttg caaaccccct accatgagac agtctactcc ctgttggata
      421 cgctcagccc tgcctaccgg gaagcatttg gaaatgctct ccttcagaga ctggaagctt
      481 tgaaacgaga tggacagtcc tgactcagtc tcctgagggg ctgctgctgg tgtagagtct
      541 cacgtaagac ttgacgccct gcatatcatc actgtggaaa gtgcatcgct ggcttatgtg
      601 ctcaccatgc cttccatgta ggcttttgac tcagcataat tgactcataa actgtcttag
      661 tttcagattc gtttaagggg actgtgagcc cattgctctg acactgtcct tctgagtttt
      721 acagacacag tcactctgca tctccatacc taatcagtac tccattctct tatgacaggg
      781 cttcaacgct gccagcactc ttctttacat agaaaattct agatttgcac agtgatatag
      841 aaattagaat cgcctaactt gagacctgga ttcagcctgc taaatcaggg gtttactact
      901 agcttggact aatgttgtag tggttatttt gttactggcc ttattggaaa caaaccgtcg
      961 actgcacaaa ttttgagatt tactgctcta ctcaatctac ttaccaaaca gactgatgaa
     1021 gacaaactgc ttatctgtta cgtaactagg ataaaatgaa aggcagggca gaaataattc
     1081 tctattcctt gtttgcaaca gccagccaac ctagatggac agaccattag caaatgaatg
     1141 tatcagttac tcatctccac gctatctaag cacatgagca aatagaggac caggccccac
     1201 ctcagcctcc gctgtggaca aggaagagga tcctggtttc cccggaaacc gtatcttggc
     1261 ctgtgttggt tcttactccg aacgtttgtt tacaatgtac agtatatata tgcacatata
     1321 tattcagaaa gtatttttgc ttcaatgctt ccctttctat aaagccgtgc tttggtattc
     1381 ctacagcacc cttcctcccc agcagttggg cagagcactg tcccattgcc acatgaacag
     1441 tgtatcatga gtgcattgta tggtttgaaa ccaaaggacg aatgaagcat tcagaaactt
     1501 gatatttaaa aaaagagatg ctctgtattt tatattttat tacagttcct ggtgtttata
     1561 aacttaataa aagtcctcca tgctgctgca tgttttccag tatgtgacaa acagaaaaaa
     1621 aaaaaaaaa
//
