LOCUS       NM_001134495            1529 bp    mRNA    linear   ROD 24-MAY-2024
DEFINITION  Rattus norvegicus gasdermin C (Gsdmc), transcript variant 1, mRNA.
ACCESSION   NM_001134495 XM_001070766
VERSION     NM_001134495.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1529)
  AUTHORS   Watabe,K., Ito,A., Asada,H., Endo,Y., Kobayashi,T., Nakamoto,K.,
            Itami,S., Takao,S., Shinomura,Y., Aikou,T., Yoshikawa,K.,
            Matsuzawa,Y., Kitamura,Y. and Nojima,H.
  TITLE     Structure, expression and chromosome mapping of MLZE, a novel gene
            which is preferentially expressed in metastatic melanoma cells
  JOURNAL   Jpn J Cancer Res 92 (2), 140-151 (2001)
   PUBMED   11223543
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000007.1.
            
            On Aug 29, 2008 this sequence version replaced XM_001070766.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            RNAseq introns :: mixed sample support SAMEA5760389, SAMEA5760434
                              [ECO:0006172]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-211               JAXUCZ010000007.1  97495138-97495348   c
            212-398             JAXUCZ010000007.1  97494338-97494524   c
            399-561             JAXUCZ010000007.1  97492926-97493088   c
            562-673             JAXUCZ010000007.1  97489645-97489756   c
            674-763             JAXUCZ010000007.1  97487051-97487140   c
            764-793             JAXUCZ010000007.1  97486606-97486635   c
            794-820             JAXUCZ010000007.1  97486365-97486391   c
            821-960             JAXUCZ010000007.1  97485256-97485395   c
            961-1090            JAXUCZ010000007.1  97484653-97484782   c
            1091-1164           JAXUCZ010000007.1  97484148-97484221   c
            1165-1529           JAXUCZ010000007.1  97483257-97483621   c
FEATURES             Location/Qualifiers
     source          1..1529
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="7"
                     /map="7q33"
     gene            1..1529
                     /gene="Gsdmc"
                     /gene_synonym="Gsdmc1; Mlze"
                     /note="gasdermin C"
                     /db_xref="GeneID:299908"
                     /db_xref="RGD:1308989"
     CDS             1..1404
                     /gene="Gsdmc"
                     /gene_synonym="Gsdmc1; Mlze"
                     /note="isoform 1 is encoded by transcript variant 1;
                     gasdermin C1; melanoma-derived leucine zipper,
                     extra-nuclear factor; melanoma-derived leucine
                     zipper-containing extranuclear factor"
                     /codon_start=1
                     /product="gasdermin-C isoform 1"
                     /protein_id="NP_001127967.1"
                     /db_xref="GeneID:299908"
                     /db_xref="RGD:1308989"
                     /translation="MLYTFDQVSKDVVKKLQGKDLRPVRCLSDATKFRQFDILQKTPQ
                     SLFFKSEDTPVGYSLLQILEPNFPVPETEVSAPMPLKHITSQKWKADVDVKATIADGG
                     ASAEFVQSCGYDIEVQSRSIPDSKLESLQNRKLLDKKLSFVTDCQMGRNNLYVVTEVF
                     EVTKDTVVQGSSSIDLSGKALVSQLVKGEAQGQWQRETTDLVPIPKGAVLAYKKKQLV
                     IENNTCAILLSANAKKKTFPGIFNFGMSSRSQTMEIGSWIDYIPPIGRIEEPVHLDFK
                     YLEKEVFLRKEQLAMLSKDVQDVVFSNLLPMLSDSDVLFDLINMLELDQLGHMDGPAG
                     LILDELRKNSSTPWIDLKGLILYLLQALMVLSDTQLDLLAQSMEMRILLQQRELVRSI
                     LEPNFKYPWNIPFTLQPQLLAPLQGEGLAITYELLKGCGLKMEPNSPRSTWDLEAKMP
                     LSALYGILSCLQQLVEA"
     exon            1..211
                     /gene="Gsdmc"
                     /gene_synonym="Gsdmc1; Mlze"
                     /inference="alignment:Splign:2.1.0"
     exon            212..398
                     /gene="Gsdmc"
                     /gene_synonym="Gsdmc1; Mlze"
                     /inference="alignment:Splign:2.1.0"
     exon            399..561
                     /gene="Gsdmc"
                     /gene_synonym="Gsdmc1; Mlze"
                     /inference="alignment:Splign:2.1.0"
     exon            562..673
                     /gene="Gsdmc"
                     /gene_synonym="Gsdmc1; Mlze"
                     /inference="alignment:Splign:2.1.0"
     exon            674..763
                     /gene="Gsdmc"
                     /gene_synonym="Gsdmc1; Mlze"
                     /inference="alignment:Splign:2.1.0"
     exon            764..793
                     /gene="Gsdmc"
                     /gene_synonym="Gsdmc1; Mlze"
                     /inference="alignment:Splign:2.1.0"
     exon            794..820
                     /gene="Gsdmc"
                     /gene_synonym="Gsdmc1; Mlze"
                     /inference="alignment:Splign:2.1.0"
     exon            821..960
                     /gene="Gsdmc"
                     /gene_synonym="Gsdmc1; Mlze"
                     /inference="alignment:Splign:2.1.0"
     exon            961..1090
                     /gene="Gsdmc"
                     /gene_synonym="Gsdmc1; Mlze"
                     /inference="alignment:Splign:2.1.0"
     exon            1091..1164
                     /gene="Gsdmc"
                     /gene_synonym="Gsdmc1; Mlze"
                     /inference="alignment:Splign:2.1.0"
     exon            1165..1529
                     /gene="Gsdmc"
                     /gene_synonym="Gsdmc1; Mlze"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atgctctaca catttgacca ggttagcaag gatgtggtca aaaagcttca aggaaaagat
       61 ctgaggccag tcagatgcct gtcagatgca accaaattcc gccagtttga catacttcag
      121 aagactccgc agtcattgtt ctttaaatct gaagatactc cggtcggata ttcccttctg
      181 cagatcttgg agcccaattt tcccgtccca gagactgaag tgtcagctcc catgcccctc
      241 aaacacatca cgtcccagaa atggaaggct gatgtggacg tcaaagccac cattgcagac
      301 ggaggtgcat cggcagagtt tgttcagtcc tgtggatatg acatcgaggt tcagagtagg
      361 agcatcccgg attcgaaact ggaaagtctc caaaacagga aactcttgga taagaagctg
      421 tcatttgtga cagattgcca gatgggaagg aacaacttgt atgtggtgac agaggtcttt
      481 gaagtgacca aggataccgt ggtgcaaggc agcagcagta ttgacctttc aggcaaagcg
      541 ctcgtctccc agttggtcaa gggtgaagcc cagggacagt ggcaaaggga aacaacagat
      601 ttagtaccta tcccaaaggg tgcagtgttg gcctacaaga agaagcaatt ggtcattgag
      661 aataacactt gtgccattct cctttctgct aatgctaaga agaagacctt tccaggaata
      721 tttaatttcg gaatgtcgtc acgtagtcaa accatggaga taggctcgtg gatagattac
      781 atccctccaa ttggacgtat agaggagccc gtccatctag atttcaagta cctagaaaag
      841 gaagttttcc tacgcaaaga gcagctggct atgctctcaa aggatgttca agatgttgtg
      901 ttctccaatc tcctgcccat gctcagtgac agtgatgttc tgtttgacct gataaacatg
      961 ctggagttgg atcagttggg gcacatggat ggcccagctg gcttaatcct agatgagctg
     1021 agaaagaact caagcacccc atggattgac ctaaagggac tcattcttta tctccttcaa
     1081 gccctaatgg tgctgagtga tacccaactc gatctgctgg cccagtctat ggagatgcgg
     1141 atcctcctgc agcaaagaga gctggtaagg agcatcctag agccaaactt caagtatccc
     1201 tggaacattc ccttcacact ccagcctcag cttctcgccc cactccaggg tgagggcttg
     1261 gccattactt acgaattgct gaaggggtgt ggtctgaaga tggagccgaa tagtcccagg
     1321 tcaacttggg atttggaagc caagatgccc ctgtcggctc tttacgggat cctgtcatgt
     1381 ttacagcaac tggtggaagc ctaaatcttc ctccgagccc ggcctcagtc ctagatacat
     1441 tggagatact gcactatcag cattcacaag agtggtgatt tcagtgcatg ctttaggctg
     1501 gtgggaataa agatgcaatg ttttttttt
//
