LOCUS       NM_001108297            2910 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus gasdermin A (Gsdma), mRNA.
ACCESSION   NM_001108297 XM_001081404 XM_340894
VERSION     NM_001108297.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2910)
  AUTHORS   Saeki,N., Kim,D.H., Usui,T., Aoyagi,K., Tatsuta,T., Aoki,K.,
            Yanagihara,K., Tamura,M., Mizushima,H., Sakamoto,H., Ogawa,K.,
            Ohki,M., Shiroishi,T., Yoshida,T. and Sasaki,H.
  TITLE     GASDERMIN, suppressed frequently in gastric cancer, is a target of
            LMO1 in TGF-beta-dependent apoptotic signalling
  JOURNAL   Oncogene 26 (45), 6488-6498 (2007)
   PUBMED   17471240
REFERENCE   2  (bases 1 to 2910)
  AUTHORS   Saeki,N., Kuwahara,Y., Sasaki,H., Satoh,H. and Shiroishi,T.
  TITLE     Gasdermin (Gsdm) localizing to mouse Chromosome 11 is predominantly
            expressed in upper gastrointestinal tract but significantly
            suppressed in human gastric cancer cells
  JOURNAL   Mamm Genome 11 (9), 718-724 (2000)
   PUBMED   10967128
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473948.1.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_340894.3, XM_001081404.1.
FEATURES             Location/Qualifiers
     source          1..2910
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="10"
                     /map="10q31"
     gene            1..2910
                     /gene="Gsdma"
                     /gene_synonym="Gsdma1"
                     /note="gasdermin A"
                     /db_xref="GeneID:360619"
                     /db_xref="RGD:1592062"
     exon            1..91
                     /gene="Gsdma"
                     /gene_synonym="Gsdma1"
                     /inference="alignment:Splign:2.1.0"
     exon            92..310
                     /gene="Gsdma"
                     /gene_synonym="Gsdma1"
                     /inference="alignment:Splign:2.1.0"
     CDS             97..1437
                     /gene="Gsdma"
                     /gene_synonym="Gsdma1"
                     /note="gasdermin A1"
                     /codon_start=1
                     /product="gasdermin-A"
                     /protein_id="NP_001101767.1"
                     /db_xref="GeneID:360619"
                     /db_xref="RGD:1592062"
                     /translation="MTMFENVTRALARQLNPRGDLTPLDSLIDFKCFHPFCLVLRKRK
                     STLFWGARYVRTDYTLLDLLEPGNTPSDPTDGGNFSFKNMLDARVEGDVDVPKTVKVK
                     GTAGLSQSSTLEVQTLSVAPKALESLHKERKLSADHPFLKEMWERGENLYVVMEVVET
                     VQEVTLERAGKAEGCFSLPFFAPLGLQGSLNHKEAVTIPKGCVLAYRVRQLMVNGKDE
                     WDIPHVYNDSMQTFPPGEKPGEGKFILIQASDVGEMHDDFKTLKEEVRRETREIEKLS
                     QVGRSSLLTSLRHLLGKKKELQDLEHTLEGALDKGHEVTLEALPKDVLLSKDAMDAIL
                     YFLGALTVLSEAQQKLLVKSLEKEILPLQLKLVESTLEQNFLQDKEGVFPLRPDLLSS
                     LGEEELTLTEALVGLSGLEVQRSGPQYTWDPDTLPHLCALYAGLSLLQLLSMGS"
     exon            311..491
                     /gene="Gsdma"
                     /gene_synonym="Gsdma1"
                     /inference="alignment:Splign:2.1.0"
     exon            492..657
                     /gene="Gsdma"
                     /gene_synonym="Gsdma1"
                     /inference="alignment:Splign:2.1.0"
     exon            658..754
                     /gene="Gsdma"
                     /gene_synonym="Gsdma1"
                     /inference="alignment:Splign:2.1.0"
     exon            755..802
                     /gene="Gsdma"
                     /gene_synonym="Gsdma1"
                     /inference="alignment:Splign:2.1.0"
     exon            803..829
                     /gene="Gsdma"
                     /gene_synonym="Gsdma1"
                     /inference="alignment:Splign:2.1.0"
     exon            830..850
                     /gene="Gsdma"
                     /gene_synonym="Gsdma1"
                     /inference="alignment:Splign:2.1.0"
     exon            851..1005
                     /gene="Gsdma"
                     /gene_synonym="Gsdma1"
                     /inference="alignment:Splign:2.1.0"
     exon            1006..1120
                     /gene="Gsdma"
                     /gene_synonym="Gsdma1"
                     /inference="alignment:Splign:2.1.0"
     exon            1121..1194
                     /gene="Gsdma"
                     /gene_synonym="Gsdma1"
                     /inference="alignment:Splign:2.1.0"
     exon            1195..2910
                     /gene="Gsdma"
                     /gene_synonym="Gsdma1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cagtcgttct ctcaacctgt agaaagaaca agttctggtt cctcaccaca cacccagctg
       61 acggacagga cccagcatca ctccctccct gagacaatga ctatgttcga gaatgtcacc
      121 cgggcgctgg ctagacagct gaaccctcga ggggatctga cacccctaga cagcctcatt
      181 gacttcaaat gcttccatcc cttttgcctg gtgctgagga agaggaagag tacactgttc
      241 tggggggccc gctacgtccg caccgactac actctcctgg atctgctgga gcctggcaac
      301 accccctcag atccaacaga tggcgggaac ttcagcttta agaatatgct ggatgcccgg
      361 gtcgaggggg acgtggacgt gccgaagaca gtgaaggtaa aggggaccgc aggcctgtca
      421 caaagcagca cactggaggt gcagacactc agcgtagctc ccaaggctct ggagagcctg
      481 cacaaagaga ggaaactgtc agcagatcac ccatttctga aggagatgtg ggaacgcggg
      541 gagaacctgt atgtggtgat ggaggtggtg gaaaccgtgc aggaagtcac tctggagcga
      601 gctggcaagg cagagggctg cttctctctc cccttctttg ccccactggg actacaggga
      661 tccttaaacc acaaggaggc tgtaaccatt cccaagggct gtgtcctggc ttatcgagtg
      721 agacaactga tggtcaatgg gaaagatgag tgggacatcc cacacgttta caatgacagc
      781 atgcaaacct tccctcccgg agaaaagcca ggagaaggga agttcatact gatccaggca
      841 tctgatgtcg gggagatgca cgacgacttc aagacattaa aagaagaggt tcggcgtgag
      901 actcgagaaa tagagaagtt gagtcaagtg gggcgaagct ccctactcac ttccctcaga
      961 catctcctag gaaagaagaa agagctccag gaccttgagc atacgcttga aggggctcta
     1021 gacaagggac acgaagtgac cctggaagca ctccccaagg atgtcctgct gtcgaaggat
     1081 gctatggacg ccatcctata cttccttggg gctctgacag tgctaagtga agcccagcag
     1141 aagcttctag tgaaatcctt ggagaaagag atcctaccac tgcaactgaa actggttgaa
     1201 agcaccttgg agcagaactt cctgcaagat aaagaaggtg tcttccccct gcggcctgac
     1261 ctgctctcct ccctcgggga ggaggaactg accctaacag aagcactggt gggactaagc
     1321 ggcctggaag tccagaggtc cggcccccag tacacgtggg atccagacac cctcccccac
     1381 ctctgtgccc tctacgctgg tctctccctc cttcagctgc taagcatggg ttcctaatgc
     1441 accttcttgg cctgcttccc taacgcctcc cagcctcact gtgctctatc tgtaacactc
     1501 aagacactac agagcctcca ggctgaggat aactgaaatg ccagctcctc catggtcacc
     1561 aagttccccc tgcctcacca tctctctatc ccctgccctc cagctcagca ccccctaagc
     1621 ccatctcctg atgcttaaat cctgaagata cagaatcatt caaaccctta ttactttgag
     1681 ccacttcatt aaaggggggg gagggggctg gggtgggagt gtgtgtgggg tatacgactt
     1741 taatcccagc attcctgagg cagaggcagg taaatctctt aagttcgagg ccagcctggt
     1801 ctacagagtg agttccagga cagccagagt tacacaagac aaccctgtct caaaacaaca
     1861 acaacaacca caacaacaca acaaccacaa caaaaaccac attcacttcc catgcgtgtc
     1921 tccgaaaaaa tattagccat tcaagaatga atgaaaatat tatgtcaacc ctaggacaag
     1981 ctgtcttctg gtttttctgt aaagggaatg gttcatttgt gccaggtaaa gaaacagaca
     2041 ttatccataa gcacatgata ctgctcgcac tgtcctcagg ctggcgggaa aatgctccag
     2101 gaactcagag ggttagaatt cagagtgtct gctttacttg agaagatcat cgaagcagtg
     2161 tgacttcacc aaagagcccc tgttctccag ccatggttga gagcttggga gagggaaaga
     2221 gaggtctaga ggactatgat gcaagcacaa aacaacacat tctcatgttg attatgtaga
     2281 aaatgggggc tggagagatg gctcagtggt taagagcact gactgctctt ccagaggtcc
     2341 tgagttcaaa tcccagcaac cacatggtgg ctcacaacca tctgtaatgg gatctgatgc
     2401 cctcttctgg tgtgtctgaa gacagctaca gtgtacttat atataataaa taaataaatc
     2461 tttaaaaaaa aaagaattaa gtagaaaatg aaggtgagat cctatctcaa aaaaaaatta
     2521 aattagagga agaggaagga ggggcaccca agaataagac ctaaaccctt ttttttttct
     2581 ttttcttttt tttttttttt ggttcttttt ttccggagct gggaaccaaa cccagggcct
     2641 tgtgcttgct aggcaagcgc tctaccactg agccaaatcc ccaaccccag acctgaacct
     2701 tttaaacagt ggtttgacct gtgggtcttg accccttcgg gaggtcaaat gactcagagg
     2761 cgttacatac cagatatcct gcatatcaga tatttacctt acgactcaga acagttgcaa
     2821 aattgctatg aaggagcaac caaaataacc ctatggttgg gggtcaccac agcacgagga
     2881 actggattaa agggttgcgg tgttgggaag
//
