LOCUS       NM_001191935            1077 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus glutaredoxin and cysteine rich domain containing
            1 (Grxcr1), mRNA.
ACCESSION   NM_001191935 XM_573590
VERSION     NM_001191935.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1077)
  AUTHORS   Liu,C., Luo,N., Tung,C.Y., Perrin,B.J. and Zhao,B.
  TITLE     GRXCR2 Regulates Taperin Localization Critical for Stereocilia
            Morphology and Hearing
  JOURNAL   Cell Rep 25 (5), 1268-1280 (2018)
   PUBMED   30380417
REFERENCE   2  (bases 1 to 1077)
  AUTHORS   Odeh,H., Hunker,K.L., Belyantseva,I.A., Azaiez,H., Avenarius,M.R.,
            Zheng,L., Peters,L.M., Gagnon,L.H., Hagiwara,N., Skynner,M.J.,
            Brilliant,M.H., Allen,N.D., Riazuddin,S., Johnson,K.R., Raphael,Y.,
            Najmabadi,H., Friedman,T.B., Bartles,J.R., Smith,R.J. and
            Kohrman,D.C.
  TITLE     Mutations in Grxcr1 are the basis for inner ear dysfunction in the
            pirouette mouse
  JOURNAL   Am J Hum Genet 86 (2), 148-160 (2010)
   PUBMED   20137774
REFERENCE   3  (bases 1 to 1077)
  AUTHORS   Hendrickx,A., Beullens,M., Ceulemans,H., Den Abt,T., Van Eynde,A.,
            Nicolaescu,E., Lesage,B. and Bollen,M.
  TITLE     Docking motif-guided mapping of the interactome of protein
            phosphatase-1
  JOURNAL   Chem Biol 16 (4), 365-371 (2009)
   PUBMED   19389623
REFERENCE   4  (bases 1 to 1077)
  AUTHORS   Erven,A., Skynner,M.J., Okumura,K., Takebayashi,S., Brown,S.D.,
            Steel,K.P. and Allen,N.D.
  TITLE     A novel stereocilia defect in sensory hair cells of the deaf mouse
            mutant Tasmanian devil
  JOURNAL   Eur J Neurosci 16 (8), 1433-1441 (2002)
   PUBMED   12405956
REFERENCE   5  (bases 1 to 1077)
  AUTHORS   Beyer,L.A., Odeh,H., Probst,F.J., Lambert,E.H., Dolan,D.F.,
            Camper,S.A., Kohrman,D.C. and Raphael,Y.
  TITLE     Hair cells in the inner ear of the pirouette and shaker 2 mutant
            mice
  JOURNAL   J Neurocytol 29 (4), 227-240 (2000)
   PUBMED   11276175
REFERENCE   6  (bases 1 to 1077)
  AUTHORS   DEOL,M.S.
  TITLE     The anatomy and development of the mutants pirouette, shaker-1 and
            waltzer in the mouse
  JOURNAL   Proc R Soc Lond B Biol Sci 145 (919), 206-213 (1956)
   PUBMED   13336002
COMMENT     INFERRED REFSEQ: This record is predicted by genome sequence
            analysis and is not yet supported by experimental evidence. The
            reference sequence was derived from JAXUCZ010000014.1.
            
            On Jul 17, 2010 this sequence version replaced XM_573590.3.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26360172.1822475.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760393,
                                           SAMEA5760433 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-449               JAXUCZ010000014.1  40480045-40480493   c
            450-692             JAXUCZ010000014.1  40416506-40416748   c
            693-758             JAXUCZ010000014.1  40366193-40366258   c
            759-1077            JAXUCZ010000014.1  40358077-40358395   c
FEATURES             Location/Qualifiers
     source          1..1077
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="14"
                     /map="14p11"
     gene            1..1077
                     /gene="Grxcr1"
                     /gene_synonym="RGD1564635"
                     /note="glutaredoxin and cysteine rich domain containing 1"
                     /db_xref="GeneID:498355"
                     /db_xref="RGD:1564635"
     exon            1..449
                     /gene="Grxcr1"
                     /gene_synonym="RGD1564635"
                     /inference="alignment:Splign:2.1.0"
     CDS             66..938
                     /gene="Grxcr1"
                     /gene_synonym="RGD1564635"
                     /note="glutaredoxin, cysteine rich 1; glutaredoxin
                     domain-containing cysteine-rich protein 1-like"
                     /codon_start=1
                     /product="glutaredoxin domain-containing cysteine-rich
                     protein 1"
                     /protein_id="NP_001178864.1"
                     /db_xref="GeneID:498355"
                     /db_xref="RGD:1564635"
                     /translation="MLRRETKPESDRPRKVRFRIASSHSGRVLKEVYEDGQAPGSLDS
                     ECASVCAIDGLSDSEGHQNGHIGLEDNEQEKDQDNLLVLARTASEKAFGTRRVNILSK
                     NGTVRGVKYKVSAGQALFNNLTKVLQQPSADLEFDRVVIYTTCLRVVRTTFERCELVR
                     KIFQNHRVKFEEKNIALNGDYGKELDERCRRVSEAPSLPVVFIDGHYLGGAEKILSMN
                     ESGELQDLLTKIERVQHPHECPSCGGFGFLPCSVCHGSKMSVFRNCFTDAFKALKCTA
                     CNENGLQRCKNCAC"
     exon            450..692
                     /gene="Grxcr1"
                     /gene_synonym="RGD1564635"
                     /inference="alignment:Splign:2.1.0"
     exon            693..758
                     /gene="Grxcr1"
                     /gene_synonym="RGD1564635"
                     /inference="alignment:Splign:2.1.0"
     exon            759..1077
                     /gene="Grxcr1"
                     /gene_synonym="RGD1564635"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggcaaggaga tgaactgaca gcagatccat aatggtgtaa actgttcgtg tgggtggagg
       61 tgaccatgct aagaagggag acaaagccag aaagtgacag gccacggaaa gtccggtttc
      121 ggattgcctc atctcacagt gggagagttc tgaaagaggt ctatgaagat ggacaagcac
      181 caggctctct ggattctgaa tgtgctagtg tctgtgcaat agatgggcta agtgactctg
      241 agggacatca aaatggccac attggattgg aagataacga acaggagaaa gatcaggata
      301 acctgctggt attagccagg acagccagtg agaaggcttt tggtacgaga agagtcaaca
      361 ttttaagcaa aaatggtaca gtcagaggcg tcaaatacaa agtgagtgct ggccaggctc
      421 tgtttaacaa tttgaccaaa gtgttacagc aaccatcagc tgacctggaa tttgaccggg
      481 tagtgattta tacaacctgc cttcgtgtgg tgaggacgac ctttgagaga tgtgaactgg
      541 ttagaaagat cttccaaaac caccgagtaa aatttgaaga gaaaaacata gctctaaatg
      601 gtgactatgg gaaagagttg gatgaacgat gcaggagagt ctctgaagct ccttctctcc
      661 ctgttgtctt cattgatggc cattatcttg ggggtgctga gaaaattttg tcaatgaacg
      721 aatcaggaga actgcaagac cttttaacca aaattgagag agtccagcat ccacacgagt
      781 gtccctcctg tggaggcttc ggcttccttc catgctctgt gtgccacggg agcaagatgt
      841 cagtgtttcg caattgcttt acggacgctt tcaaagccct gaagtgtaca gcttgcaacg
      901 agaatggtct tcagcgctgt aagaactgcg cctgctaact ggatcttctg cctagagaaa
      961 gcctcatttc cttaaacaaa ggataacatt tggcttctgc cttttttaaa aaaaagaatg
     1021 tcatgttttt agattaaaca ataaagtttg tatattataa ttacctctgt tttaaaa
//
